Scale effects, which can influence the reliability and effectiveness of experimental results, are often unavoidable but seldom explored, particularly in the context of plunging waves. To investigate the scale effects of plunging wave impacts on a vertical cylinder, experiments were conducted in a wave flume at model scales of 1:20, 1:30 and 1:40. The wavemaker movements were scaled based on the Froude-similarity law and the pressures on the front surface of the cylinder were analyzed. The results indicated that plunging waves were generated across these three scales, with fine agreement in overall wave elevations and a local waveform similarity of 80–90%. The analysis of pressures showed that the distribution of peak pressures on the cylinders remained consistent across different scales; however, scale effects were closely related to the intensity of wave impacts. Specifically, in cases of relatively weak impact, such as when the wavefront struck the cylinder before breaking or even after an intense wave breaking with intense gas-liquid mixtures, the pressure discrepancies were less than 20% among these different scales. This discrepancy can exceed 50% near the wave peaks during the vertical wave front or early jet formation stages with strong impacts.