Long-term use of desktop displays may increase the burden of the visual system and users can use low blue light mode for eye protection in terms of circadian effect. In this work, we investigated its influence from two aspects of brightness-visual effect, namely efficacy and circadian effect, and color quality, namely color difference Δu’v’ (chromaticity coordinate offset of two colors), and Duv (deviation from blackbody locus). The decrease of brightness is accompanied by the increase of efficacy while diminishing circadian effect. The blue, cyan, and magenta have the largest Δu’v’, and the lower the saturation, the greater the Δu’v’. The lower the correlated color temperature (CCT), the greater the Duv and the farther it deviates from the Planckian locus. We summarize three low blue light mode adjustment strategies based on red, green, and blue three-channel ratio of spectrum, and propose an optimized mode using genetic algorithm, which has two optional CCT ranges of 3500–5000 K and 2700–3000 K. Furthermore, we establish the relationship between brightness and gamut coverage to refine the screen brightness range for low blue light mode. This research provides valuable insights into low blue light mode application and their implications for human-centric healthy displays.
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