Pittsburgh Sleep Quality Index Scale Research Articles

Effect of Third Molar Surgery on Sleep Health Parameters of Young Adults: An Observational Study

Background and Objectives: The role of surgical extraction of the third molar in patients’ sleep quality remains unclear, although it is one of the most common oral surgical procedures. The aim of this study is to assess the changes in patient-reported sleep health outcomes after third molar surgery and to investigate any associations between sleep parameters and post-extraction pain. Materials and Methods: Young adults without known comorbidities who were in need of mandibular third molar surgical extraction were included. All participants completed a sleep diary, the Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI) and Athens Insomnia Scale (AIS) questionnaires, which were used to assess sleep habits, daytime sleepiness, sleep quality and insomnia severity one week before and after extraction. In addition, a visual analog scale was completed postoperatively to assess the perception of pain. Results: Out of 75 patients who completed the study protocol, 32 (42.7%) were males and 43 (57.3%) were females, with a mean age of 24.01 (±3.43) years. Postoperatively, statistically significant higher scores were observed for PSQI [4.85 (±2.32) before vs. 5.39 (±2.75) after, p = 0.041], AIS [5.56 (±3.23) before vs. 6.91 (±4.06) after, p < 0.001] and average weekly number of nocturnal awakenings [2.01 (±3.72) before vs. 4.19 (±5.20) after, p < 0.001] but not for ESS, average weekly sleep duration and average weekly sleep onset latency. Pain perception was increased in patients who slept worse on almost all seven postoperative days, although this did not reach statistical significance. Conclusions: Third molar surgery impacts sleep quality and insomnia severity in the first week after extraction, while there is no effect on daytime sleepiness. The worsening of subjective sleep symptoms after extraction may be associated with an increased perception of pain.

Modular multimodal hospital-home chain physical activity rehabilitation programme (3M2H-PARP) in liver cancer: a protocol for a randomised controlled trial

IntroductionPatients with liver cancer are susceptible to experiencing a decline in muscle mass and function, which can lead to physical frailty and have a negative impact on prognosis. However, there...

Influence of sleep quality and other associated factors on glycemic control among diabetic patients: A hospital-based study

The glycemic control of diabetes patients is influenced by a variety of risk factors, some of which are adjustable and others of which are not. Diabetes and sleep quality are most frequently correlated in both directions. To evaluate the quality of sleep and pinpoint the risk factors for inadequate glycemic control in individuals with diabetes. : This cross-sectional study included seventy consecutive patients who met the inclusion criteria. The Pittsburgh Sleep Quality Index (PSQI) scale was used to evaluate the quality of sleep. Siemens- ID 29984, dimension RxL Max, Architect plus ABBOT (ci 4100), completely automatic seven-part cell-counter by Horiba Pentra Dx and Siemens ADVIA Centaur XPT (Immonoassay system) were utilized for the biochemical tests.: Of the 70 participants in the study, 22 patients [31.4%] reported having good sleep quality, while 15 patients [21.4%] had average sleep quality and 33 patients [47.1%] had poor sleep quality. Patients with managed and uncontrolled blood sugar showed varying degrees of sleep quality; 48.4% and 17.9% showed good sleep quality, 29% and 15.4% showed moderate sleep quality, and 22.6% and 66.7% showed poor sleep quality. A statistically significant difference (p<0.001) was seen in the sleep quality of the two groups. : In summary, the results of our study suggested that diabetics with poor sleep quality are more likely to have poor glycemic control. A significant modifiable risk factor for improved glycemic management in diabetic patients is sleep quality.

Parental and Child Sleep: Children with Vision Impairment, Autistic Children, and Children with Comorbid Vision Impairment and Autism.

Parents report associations between children's sleep disturbances and behaviors. Children with neurodevelopmental conditions (e.g., Williams Syndrome and autism) are consistently reported to experience increased sleeping problems. Sleep in children with vision impairment and children with a dual diagnosis of vision impairment and autism remains understudied. Our exploratory study compared sleep profiles in 52 children (aged 4-12 years) and their parents (n = 37), across four groups: children with vision impairment (VI; n = 9), autism (n = 10), comorbid vision impairment + autism (n = 6), and typically developing children (n = 27). Childhood sleep was measured using the parental report Childhood Sleep Habits Questionnaire and sleep diaries. Children's cognitive functioning was measured using digit span, semantic, and phonemic verbal fluency measures. Parental sleep was measured via the Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale. Clinically disordered sleep was reported in all child groups (p ≤ 0.001), particularly children with VI + autism. Age, not sleep quality/quantity, predicted cognitive task performance in TD and autistic groups, but not in VI and VI + autism groups. The child's diagnosis affected parental sleep, particularly in children with a dual diagnosis of VI + autism. All participants experienced problematic sleep to varying degrees. Those most affected were children and parents in the VI + autism group, suggesting that autism may be the main driver of sleep problems in our sample.

Effort–reward imbalance and sleep quality in railway locomotive stewards: a cross-sectional study

ObjectiveTo assess the correlation between the effort–reward imbalance (ERI) and sleep quality among railway locomotive stewards.DesignCross-sectional study.SettingLanzhou Bureau Group, China Railway, between July and August 2022.ParticipantsRailway locomotive stewards.Primary and secondary...

Xiao-Yao-San improves sleep quality in insomnia patients with and without moderate-to-severe obstructive sleep apnea-A pilot polysomnography study

IntroductionThis single-arm pilot study aimed to investigate the effects of a 1-month Xiao-Yao-San (XYS) treatment with on objective and subjective sleep parameters among insomnia patients with and without moderate-to-severe obstructive sleep apnea (OSA). MethodsThis single-arm pre-post study included fourteen participants (average age, 48.2±15.5 years). All participants received XYS (3 g × 3 times/day, after meals) for 28 days. Among them, 7 participants had an apnea-hypopnea index (AHI) ≥15 events/hour and were classified as having moderate-to-severe OSA, while 7 patients had an AHI <15 events/hour. Polysomnography was performed to evaluate the AHI, sleep stage, sleep efficiency, and sleep latency at the beginning and after 28 days of usage. Subjective questionnaires were also administered, including the Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS-A and HADS-D), and Epworth Sleepiness Scale (ESS). The Wilcoxon test was used to compare the pre-treatment and post-treatment differences. ResultsOur 14 insomnia participants, with an average AHI of 21.2 events/hour at baseline, who were taking XYS, exhibited a statistically significant reduction in PSQI scores (reduction of -3.0; p=0.002) compared to the corresponding baseline values. The objective sleep evaluations did not show differences between participants with or without moderate-to-severe OSA after receiving XYS treatment. For subjective sleep parameters, only participants without moderate-to-severe OSA exhibited statistically significant improvements in sleep quality (PSQI score pretest/posttest: 10.0±3.5/7.0±3.5; p=0.012). ConclusionsXYS treatment may significantly improve sleep quality in participants without moderate-to-severe OSA. Further studies with larger sample sizes and longer durations are needed.

Progressive muscle relaxation alleviates anxiety and improves sleep quality among healthcare practitioners in a mobile cabin hospital: a pre-post comparative study in China.

To investigate the anxiety levels, sleep quality and potential risk factors of healthcare practitioners involved in the management of COVID-19 patients in a mobile cabin hospital, and further to assess the impact of progressive muscle relaxation (PMR) on their anxiety levels and sleep quality. We conducted a pre-post self-controlled trial. Healthcare practitioners meeting the inclusion criteria underwent daily 30-min PMR sessions for seven consecutive days. The Pittsburgh Sleep Quality Index (PSQI) and Hamilton Anxiety Scale (HAMA) were used to assess the anxiety and sleep quality of subjects pre- and post-intervention. Statistical analysis was performed using the Wilcoxon test, Mann-Whitney U test, Kruskal-Wallis H test, and Spearman rank correlation. A total of 94 participants completed the study. No statistically significant differences in HAMA or PSQI total scores were observed between groups categorized based on demographic variables such as age, sex, and years of education (p > 0.05). The PSQI total score and its components (excluding sleep medication usage) exhibited a positive correlation with the HAMA total score and its psychological anxiety component (p < 0.05), and a correlation was observed between somatic anxiety manifestations and several components of the PSQI. The PSQI total scores before and after intervention were 10.0 (8.0, 13.0) and 8.0 (6.0, 9.0) respectively (p < 0.001); the HAMA total scores were 8.0 (5.0, 13.0) and 6.0 (4.0, 9.5) respectively (p < 0.001). The detection rates of poor sleep and anxiety states, along with their severity, significantly decreased post-intervention (p < 0.001). Healthcare practitioners experience prominent anxiety and sleep issues in the mobile cabin hospital. PMR can be an effective intervention for improving the anxiety and sleep quality of healthcare professionals during support periods in the mobile cabin hospital. However, trials with larger samples are necessitated to further affirm these preliminary findings.

The Role of Anxiety and Depression in the Relationship Among Emotional Eating, Sleep Quality, and Impulsivity.

The aim of this study was to investigate the relationship among sleep quality, impulsivity, anxiety, and depression in individuals with emotional eating behavior. The study was designed as a cross-sectional study. The study included 92 individuals (age 31.29 ± 9.17; female, 67.4% [n = 62]; male, 32.6% [n = 30]) with symptoms of emotional eating but no previous psychiatric diagnosis or treatment. Participants were administered a Structured Clinical Interview for DSM-5 Disorders interview form, a sociodemographic data form, the Emotional Eating Scale, the Beck Depression Scale, the Barratt Impulsivity Scale, the Beck Anxiety Scale, and the Pittsburgh Sleep Quality Index Scale. Emotional eating is positively correlated with anxiety (r = 0.377, p = 0.001), depression (r = 0.375, p = 0.001), impulsivity (r = 0.250, p = 0.016), and poor sleep quality (r = 0.478, p = 0.001). Obese individuals (defined as having a body mass index of 30 or higher) showed higher emotional eating (z = -2.552, p = 0.016) and poorer sleep quality (z = -2.089, p = 0.044) than nonobese individuals, and women showed higher emotional eating (t = 2116, p = 0.037) and poorer sleep quality (z = -2537, p = 0.010) than men. Poor sleep quality was associated with emotional eating. In this relationship, poor sleep quality influenced emotional eating through all mediators, including anxiety and depression (B = 3.491; standardized effect, 0.485; p = 0.001). Poor sleep quality directly influenced emotional eating (B = 2.806; standardized effect, 0.390; p = 0.001). The findings of the study suggest that emotional eating is associated with higher levels of anxiety, depression, impulsivity, and sleep problems, especially in women. It suggests that the interrelationships of psychological factors associated with emotional eating should be investigated.

Monitoring adrenal insufficiency through salivary steroids: a pilot study.

Various glucocorticoid replacement therapies (GRTs) are available for adrenal insufficiency (AI). However, their effectiveness in restoring glucocorticoid rhythm and exposure lacks adequate biochemical markers. We described the diurnal salivary cortisol (SalF) and cortisone (SalE) rhythm among different GRTs and analysed the associations between saliva-derived parameters and life quality questionnaires. Control subjects (CSs, n = 28) and AI patients receiving hydrocortisone (HC, n = 9), cortisone acetate (CA, n = 23), and dual-release hydrocortisone once (DRHC-od, n = 10) and twice a day (DRHC-td, n = 6) collected 9 saliva samples from 07:00 to 23:00. Patients compiled Pittsburgh Sleep Quality Index, Hospital Anxiety and Depression Scale, and Addison disease-specific quality-of-life questionnaires. SalE and SalF were measured by liquid chromatography-mass spectrometry. Exposure was monitored using SalE for HC and DRHC and SalF for CA. Area under the curve (AUC) was computed. Different GRTs were compared by Z-scores calculated from saliva-derived parameters. Questionnaire results predictors were evaluated with multiple regression analysis. Compared with controls, all GRTs resulted in glucocorticoid overexposure in the morning. Hydrocortisone, CA, and DRHC-td caused overexposure also in afternoon and evening. Compared with other treatments, CA determined increased Z-score-07:00 (P < .001), DRHC-td determined increased Z-score-AUC07:00→14:00 (P = .007), and DRHC-od induced lower Z-score-AUC14:00→23:00 (P = .015). Z-scores-AUC14:00→16:00 ≥ .619 best predicted questionnaire scores. None of the GRTs mimics normal glucocorticoid rhythmicity and exposure. SalE, SalF, and Z-score may be useful markers for monitoring and comparing different GRTs. Excess glucocorticoid in early afternoon best associated with depressive symptoms and worse life and sleep quality.

Demographic correlates, lifestyle habits, and health effects of poor sleep quality in Indian adolescent girls living in a second-tier city

Background: Insufficient sleep, poor sleep quality, and sleepiness are common problems related to learning, memory, and school performance. During puberty, sleep habits change earlier among girls in parallel to their earlier pubertal maturity. The changes occur during adolescence in response to maturational changes and increased autonomy and independence. Aims and Objectives: This study aims to estimate the prevalence of poor sleep quality among adolescent girls in a second-tier city. Materials and Methods: Cross-sectional observational study conducted in 150 school-going adolescent girls from three different schools in a second-tier city. The study was conducted using the Pittsburgh Sleep Quality Index scale for assessment of the quality of sleep and an investigator designed pro forma to analyze various lifestyle habits. Kutcher Adolescent Depression Scale 6 was used to address the depressive symptoms. Results: Prevalence of poor sleep quality was 9.2%. Pre-bed screen time of &gt;30 min was found in 53% of girls with poor sleep quality. Overweight girls also have poor sleep quality. Good grades (&gt;90% marks in examinations) were associated with poor sleep quality. About 8.3% of girls with poor sleep quality have one or more symptoms pertaining to depression. Conclusion: The pre-bed screen time of more than 30 min in the form of any electronic screens leads to poor sleep quality and poor sleep quality is significantly associated with being overweight. Poor sleep quality is also associated with some symptoms of depression. These all are observed in the girls living in a tier two city, awareness among adolescent girls must be spread to decrease the screen time and they should also be encouraged for better sleep hygiene.

IJCM_402A: Assessment of sleep quality and risk factors associated with poor sleep quality among medical students- A cross sectional study

Background: Sleep is a periodic resting state of natural arousable unconsciousness of body and mind, which leads to the returning of body and mind. A good sleep has been shown to be essential component of health, and its deprivation linked to various diseases. Sleep deprivation is defined as getting inadequate sleep, less than 7-9 hours per day. Although, sleep deprivation is generally a disorder of elderly and sick, it has increasingly been reported among college students and is considered a global health problem Objective: To evaluate sleep quality among medical students and identify risk factors associated with poor sleep quality among them. Methodology: Study design: Cross sectional study, Study setting: GITAM Institute of medical sciences and research, Study population :Medical students from MBBS first year to final year, Study period:2 months, Inclusion criteria :Medical students of 1st,2nd,3rd,4th year Exclusion criteria: Students who has not given consent Sampling method: Convenient sampling method Sample size: prevalence=68.6%==176, Pittsburgh Sleep Quality Index (PSQI) scale was used to measure sleep quality. SPSS software is used for analysis. Results: The mean age of study participants is 20±4. PSQI score is Good sleep in 24.4%, Fairly good sleep in 49.4%,Fairly bad sleep in 10.8%,Poor sleep in 15.3%. Conclusion: Poor sleep quality among medical students is 26.1%,factors associated are mobile use and presence of chronic illness.

Vietnamese Version of Pittsburgh Sleep Quality Index: Reliability, Cut-Off Point, and Association With Depression Among Health Science Students

Background and Objective Sleep disturbances among medical students, including insufficient sleep duration and poor sleep quality, are prevalent issues with potential repercussions on mental health.Methods The study evaluated the Vietnamese version of the Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality and investigated the correlation between the results of the PSQI and Beck Depression Inventory-II (BDI-II) scales in health sciences students.Results We conducted this cross-sectional study at the School of Medicine, Vietnam National University Ho Chi Minh City, involving 906 medical, pharmaceutical, and dental students. Data were collected through a self-reporting questionnaire.Conclusions The Vietnamese version of the PSQI scale demonstrates acceptable reliability. Furthermore, positive correlations were observed between the total PSQI score and components of the BDI-II. A recommended cut-off point above 5 is proposed for identifying sleep disturbances among health sciences students using the Vietnamese PSQI. Conclusions The study affirms the reliability of the Vietnamese PSQI scale, suggesting its suitability for screening sleep disturbances among health sciences students in Vietnam. PSQI component scores significantly correlated with total BDI-II score.

A Comparative Study of Architecture and Quality of Sleep among Juvenile Myoclonic Epilepsy Patients and Healthy Individuals Attending Tertiary Care Hospital in Central India

&#x0D; &#x0D; &#x0D; &#x0D; Background and Objective: Primary sleep disorders are common in patients with epilepsy. Seizures, epileptiform discharges, and antiepileptic drugs alter the sleep architecture of patients with juvenile myoclonic epilepsy (JME). We evaluated sleep architecture and its quality in these patients.&#x0D; Materials and Methods: Thirty patients with JME (11 men and 19 women with mean age of 21.10 ± 4.55 years) and 30 healthy controls underwent overnight polysomnography (PSG). Sleep quality and daytime sleepiness were assessed using Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS), respectively.&#x0D; Results: Myoclonus and generalized tonic-clonic seizures (GTCS) were present in all patients with JME, while absence seizures were in 13.3%. Sleep deprivation was the most frequent precipitating factor for seizures (56.6%) followed by fatigue, sound, and photic stimulation. Patients with JME reported a statistically significant drop in sleep efficiency (P&lt;0.001) with prolonged sleep onset latency (P&lt;0.001). There was prolongation in the N1 stage of non-rapid eye movement (NREM) sleep (P=0.002), and reduction in the N2 stage of NREM (P&lt;0.001) and rapid eye movement (REM) sleep (P&lt;0.001). The median PSQI score was higher in patients with JME, suggesting poor sleep quality (P&lt;0.001), and the daytime sleepiness was not different as indicated by the similar median ESS score (P=0.033).&#x0D; Conclusion: Our results suggest a significant alteration in the sleep architecture of patients with JME with reduced sleep efficiency and poor sleep quality. The possible role of the disease itself is suggested for these alterations as a simi- lar trend was also observed in drug naïve patients.&#x0D; &#x0D; &#x0D; &#x0D;

Prevalence of obstructive sleep apnoea risk and its association with anthropometric indices of cardiometabolic risks and cognition in young and middle-aged adults

Objectives: Obstructive sleep apnoea (OSA), an often underdiagnosed and undertreated sleep-related breathing disorder, is associated with an increased risk of cardiovascular morbidity and mortality. Hence, this study aimed to assess the prevalence of OSA risk and its association with anthropometric indices (AI) of cardiometabolic risks, domain-specific cognitive functions and quality of sleep in apparently healthy young and middle-aged adults. Materials and Methods: One hundred and eighty-nine apparently healthy individuals (123 males and 66 females) aged 19–45 years were included in this cross-sectional study. The participant’s current risk of OSA was assessed using the STOP-Bang questionnaire, and AI indicative of cardiometabolic risk (body mass index, waist-hip ratio [W/H ratio], waist-height ratio [WHtR], conicity index and a body shape index) was assessed using standard techniques. Domain-specific cognitive tests were performed to assess the cognitive status of the individual. Quality of sleep was assessed using the Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale. The correlation between the OSA risk score and the study parameters was assessed using the Pearson or Spearman correlation coefficient test. Results: The prevalence of high current risk of moderate to severe OSA was found to be 12.7%. Significant positive correlations were observed between OSA risk score and W/H, WHtR and sleep quality scores. While a significant positive correlation was observed between OSA risk score and executive functioning, significant negative correlations were observed with the other cognitive tests (short-term memory, verbal fluency, visuospatial memory and sustained attention and response speed). Conclusion: A high risk of moderate to severe OSA is associated with obesity, cognitive decline and poor sleep quality in apparently healthy young and middle-aged adults.

Sleep habits and its associated factors among medical students of a medical college in Telangana, India

Abstract Background: Sleep is vital for cognitive function and physical and mental well-being. Medical students are prone to reduced sleep because of extensive curriculum, competitive exam, tireless night duties, fear of failure, and countless other responsibilities. Objective: This study aims to assess the sleep quality and daytime sleepiness and to determine their associated factors related to poor sleep quality among medical students. Materials and Methods: A cross-sectional study was done among 435 students among undergraduates and postgraduates in Kakatiya Medical College, Warangal, Telangana, from January 2023 to April 2023. After obtaining informed consent, the data were collected using a self-administered questionnaire, in which sleep quality and excessive daytime sleepiness was assessed using Pittsburgh Sleep Quality Index and Epworth Daytime Sleepiness Scale, respectively. The collected data were entered into Excel sheet and exported to SPSS V 20. Data analysis was done using Chi-square test, Fisher’s exact test, and Pearson’s correlation coefficient. P &lt; 0.05 was considered statistically significant. Results: Poor sleep quality and excessive daytime sleepiness were present in 297 (68.3%) and 105 (24.1%) students, respectively. Department of postgraduates, smoking, mobile phone use, academic performance, tea, coffee intake, and excessive daytime sleepiness had a significant association with poor sleep quality. Excessive daytime sleep and sleep quality had strong positive correlation (r = 0.823). Conclusion: Poor sleep quality was quite high among medical students. Daytime sleepiness was predominant among students with poor sleep.

Translating and establishing the psychometric properties of the Jenkins Sleep Scale for Arabic-speaking individuals

BackgroundThe Jenkins Sleep Scale is a widely used self-report questionnaire that assesses sleep quality and disturbances. This study aimed to translate the scale into Arabic and evaluate its psychometric properties in an Arabic-speaking population.MethodsThe Jenkins Sleep Scale was translated into Arabic using forward and backward translation procedures. The Arabic version was administered to a convenience sample of 420 adults along with the Pittsburgh Sleep Quality Index (PSQI) and Athens Insomnia Scale (AIS) for validation purposes. Reliability was examined using Cronbach’s alpha and McDonald’s omega coefficients. Confirmatory factor analysis (CFA) was also conducted to test the unidimensional factor structure. Convergent validity was assessed using correlations with PSQI and AIS scores.ResultsThe Cronbach’s alpha and McDonald’s omega values for the Arabic Jenkins Sleep Scale were 0.74 and 0.75, respectively, indicating good internal consistency. The 2-week and 4-week test-retest intraclass correlation coefficients were both 0.94 (p < 0.001), indicating excellent test-retest reliability. The CFA results confirmed the unidimensional factor structure (CFI = 0.99, TLI = 0.96, RMSEA = 0.08). The measurement model had an equivalent factor structure, loadings, intercepts, and residuals across sex, age, and marital status. Significant positive correlations were found between the Arabic Jenkins scale score and the PSQI (r = 0.80, p < 0.001) and AIS (r = 0.74, p < 0.001), supporting convergent validity.ConclusionThe Arabic version of the Jenkins Sleep Scale demonstrated good psychometric properties. The findings support its use as a valid and reliable measure for evaluating sleep quality and disturbances among Arabic-speaking populations.

ASSESSING SLEEP QUALITY AMONG MEDICAL AND DENTAL STUDENTS IN KHYBER PAKHTUNKHWA PROVINCE OF PAKISTAN: A CROSS-SECTIONAL SURVEY

Objectives: To determine the prevalence of poor sleep and factors associated with it among medical and dental students in Khyber Pakhtunkhwa province of Pakistan.Materials and Methods: A population-based analytical cross-sectional study was carried out from May to September 2022, consisting of 385 undergraduate students from 21 medical and dental colleges. A non-probability convenience sampling technique was employed to assess sleep quality with the help of Pittsburgh Sleep Quality Index (PSQI). Factors associated with poor sleep were determined using binary logistic regression.Results: Among the total, 263 (68.3%) students had poor sleep quality on the PSQI scale. Poor sleep was more likely (OR [95%CI]) among females (2.3 [1.3-3.9]), age≥21years (2.5 [1.1-5.8]), pre-clinical phase (3.1 [1.4-6.5]), BDS students (2.0 [1.1-3.5]), disrupted circadian rhythm (4.2 [2.0-8.6]), and hostelites (1.7 [1.0-2.9]) at signifi cance of P&lt;0.05. Participants’ per day sleep was 5.9hrs (SD=1.2hrs). Regarding PSQI components, the worst performance was noticed in sleep duration (M=1.60, SD=0.95). Of the total, 47 (12.2%) were taking sleep medications, 377 (97.9%) had bedtime phone usage and 242 (62.8%) had no familiarity with “Sleep hygiene”.Conclusion: Findings revealed that poor sleep was prevalent in more than half of the participants. Average sleep duration was suggestive of sleep deprivation indicating for immediate interventions to prevent its potential consequences.

The Influence of Wound Closure Techniques after Surgical Decompression in Patients with Carpal Tunnel Syndrome on Sleep Disturbance and Life Quality: A Prospective Comparison of Surgical Techniques.

The compression of the median nerve within the carpal tunnel is the cause of carpal tunnel syndrome (CTS). Surgical decompression is successful in improving sleep and quality of life, but the effect of tissue adhesives as a material for wound closure has not been investigated. The objective of the study was to evaluate sleep disorders and health-related life quality by comparing two methods for wound closure after carpal surgery in participants who were randomized to receive tissue adhesives or transcutaneous sutures. The subjects, aged 61.56 ± 12.03 years, were randomized to receive either tissue adhesives (n = 50) or suture-based wound closure (n = 50) using the Glubran Tiss 2® skin adhesive after subcutaneous running sutures. The outcomes were assessed during the 12-month postoperative follow-up. The Pittsburgh Sleep Quality Index (PQSI) and Insomnia Severity Scale (ISI) were used for the sleep disturbance assessment, and for the health-related quality of life assessment, the total SF-36 (36-Item Short Form Survey) was used. The PQSI, ISI, and SF-36 were not statistically different between groups during the follow-up, except in the ISI score two weeks after surgery (9.40 ± 1.18 in the tissue adhesive group vs. 9.96 ± 1.09 in the suture-based group, p = 0.008). The PQSI, ISI, and SF-36 scores for all the subjects and groups were persistently improved at all the follow-up intervals after surgery. The total SF-36 score increased 12 months after surgery (49.84 ± 5.85 vs. 82.46 ± 5.68, p < 0.001). Cyanoacrylate-based adhesion material can be used for wound closure after open CTS decompression as a standard transcutaneous suture, and both techniques equally lead to improved sleep and life quality. The possible advantages of tissue adhesives include a faster reduction in the ISI.

Effects of prophylactic drug therapies and anti-calcitonin peptide-related monoclonal antibodies on subjective sleep quality: An Italian multicenter study

Objective/backgroundsleep alterations strongly influence migraine severity. Prophylactic therapies have a major impact on migraine frequency and associated symptoms. The study purpose was to compare the impact of oral drug therapies or gene-related anti-calcitonin monoclonal antibodies (anti-CGRP mAbs) on sleep alterations. We also evaluated which drug therapies are more effective on sleep quality and the different impact on migraine frequency and life quality. Patients/methodsthis is a multicenter, prospective study conducted in three specialized headache centers (Marche Polytechnic University, Ancona; University of Palermo, Palermo; Fondazione Policlinico Campus Bio-Medico, Rome). At baseline, we assigned migraine patients to preventive therapy with first-line drugs or anti-CGRP mAbs. The Pittsburgh Sleep Quality Index (PSQI) and Migraine Disability Assessment (MIDAS) scales were administered. After three months, we re-evaluated the patients with the same scales. Results214 patients were enrolled. Any prophylaxis was significantly associated with a reduction in PSQI score (mean difference 1.841; 95%CI:1.413–2.269; p < 0.0001), most significantly in the anti-CGRP mAb group (mean difference 1.49; 95%CI:2.617-0.366; p = 0.010). Anti-CGRP mAbs resulted in significant improvement in migraine severity and MIDAS scores. Among oral therapies, calcium antagonists and antidepressants were the most effective in reducing PSQI score between T0 and T1 (p = 0.042; p = 0.049; p < 0.0001, respectively). Conclusionsanti-CGRP mAbs revitalized the management of migraine with stable and well-documented efficacy. Our data also suggest that anti-CGRP mAbs result in a positive effect on sleep quality, with a significant improvement in PSQI scores. Knowing the relevant impact of sleep disruption on migraine severity, these data could help for the management of migraine patients.

An investigative study of anxiety, depression and sleep quality in college students after the COVID-19 pandemic - the moderating effect of physical activity

To explore the current situation of anxiety, depression and sleep quality among college students after the COVID-19 pandemic, as well as the moderating effect of physical activity on negative emotions, and to provide a theoretical basis for colleges and universities to formulate corresponding interventions. An online cross-sectional questionnaire survey was carried out by convenience sampling method on 801 college students from China through the General Information Questionnaire (GIQ), Anxiety Self-Rating Scale (ASRS), Depression Self-Rating Scale (DSRS), Pittsburgh Sleep Quality Index Scale (PQIS), and Physical Activity Rating Scale (PARS). Data were analysed using SPSS 25.0 software and Pearson correlation was used to explore the correlations between variables. The scores of anxiety, depression, sleep quality, and physical activity level of the 801 college students included in the study after the Covid-19 pandemic were 37.15, 40.93, 2.9, and 14.44, respectively; and the detection rates of anxiety symptoms, depressive symptoms, and sleep disorders were 41.09%, 42.89%, and 30.82%, respectively. The detection rate of negative emotions was significantly higher in females than in males, and the senior group was significantly higher than the junior group in terms of depression and anxiety symptoms. The amount of physical activity of college students was significantly negatively correlated with anxiety (r=-0.691, P&lt;0.001), depression (r=-0.767, P&lt;0.001), and sleep quality (r=-0.814, P&lt;0.001); anxiety was positively correlated with depression (r=0.622, P&lt;0.001) and sleep quality (r=0.598, P&lt;0.05); and positive correlation between depression and sleep quality (r=0.512, P&lt;0.05). After the Covid-19 pandemic, college students showed different degrees of anxiety, depression and sleep disorders, the appropriate frequency of exercise can effectively improve the negative emotions of college students, and colleges and universities should pay attention to guiding the students and give them enough care and support to improve their mental health status.