Accurately and efficiently evaluating the influence of pile–soil interaction on the overall natural frequency of wind turbines is one of the difficulties in current offshore wind power design. To improve the structural safety and reliability of the offshore wind turbine (OWT) systems, a new closed-form solution method of the overall natural frequency of OWTs considering pile–soil interactions with highly effective calculations is established. In this method, Hamilton’s principle and the equivalent coupled spring model (ECS model) were firstly combined. In Hamilton’s theory, the Timoshenko beam assumption and continuum element theory considering the three-dimensional displacement field of soil were used to simulate the large-diameter monopile–soil interaction under lateral load in multilayer soil. Case studies were used to validate the proposed method’s correctness and efficiency. The results show that when compared with the data of 13 offshore wind projects reported in existing research papers, the difference between the overall natural frequency calculated by the proposed method and that reported in this study is within ±10%. This calculation method achieves the goal of convenient, fast and accurate prediction of the overall natural frequency of offshore wind systems.