The urgency of caring for the planet and scientific visions of the world have highlighted the cosmos as an authentic otherness that cannot be reduced to the mediation of human beings or man as a “microcosm”. From a Christological interpretation based on the definition of Chalcedon, a reading of the link of the cosmos with Christ through human nature, the microcosm, has been popularized. For its part, a theological tradition, in Teilhard de Chardin and Raimon Panikkar, has taken fundamental steps to overcome such an interpretative scheme. It has been recognized that by associating the created cosmos solely with human mediation, there is a risk of turning the cosmos into an instrument of use and domination. It is therefore urgent to recognize the autonomy and otherness of the cosmos and to unite it with the divine and with the human in Christ, proceeding in fidelity to the spirit of Chalcedon.