Physicochemical Research Articles

Farm Waste Management and Recycling for Negative Carbon Sink in Agriculture: A Review

The increase in global agricultural production generates a considerable amount of agriculture wastes which constitutes nuisance of environment’s population health and contributing in the global greenhouse gas (GHG) emission. However, well-managed waste mitigates these countries GHGs emissions. This chapter provides an overview of the different types of waste from agricultural activities; their composition and their sustainable management for a reduction of greenhouse gas emissions. This review highlights the importance of sustainable management of agricultural waste for limiting greenhouse gas emissions by analyzing their contribution to improve the physicochemical properties; soil fertility and their role in order to enhance the capacity of soils to sequester organic carbon.

Chemically Crosslinked Alginate Hydrogel with Polyaziridine: Effects on Physicochemical Properties and Promising Applications.

Alginate biopolymer is widely employed in many industrial fields thanks to its pleasing features of biodegradability, biocompatibility, low toxicity, and relatively low cost. The gelling process of alginate with divalent cations is fairly simple and thus it is used as a versatile biomaterial to tailor the desired mechanical and moisture properties. This study focused on developing new gel formulations to enhance the properties of calcium-alginate hydrogel (CA). The newly synthesized hydrogels, referred to as CA-CHEM gels, were chemically cross-linked with different ratios of pentaerythritol tris[3-(1-aziridinyl)propionate] (PTAP) through the reaction between the carboxylic groups of alginate and aziridines of PTAP. The reaction was successfully monitored by NMR. The new CA-CHEM gels were chemically characterized using FTIR-ATR, while SEM analysis confirmed the changes in the porosity and homogeneity of the network. Additionally, thermogravimetric analyses and mechanical properties showed improvement in degradation stability and in structural strength, compared to plain CA, with an increasing PTAP content up to 1% w/w. Finally, the new CA-CHEM gels effectively controlled water absorption and release. In particular, CA-CHEM-1 performed as the most controlled system, making it promising for delivering aqueous cleaning solutions on water-sensitive surfaces such as a wooden historical musical instrument.

Autecology and determination of relationships between nutrients in soil and sage plant (Salvia eremophila Boiss.) in the south of Yazd province.

This study aims to investigate the autecology and determine the relationship between the nutritional elements in the soil and the Sage plant (Salvia eremophila Boiss.) in the south of Yazd province. The main habitats were determined, which contained various ecological characteristics. Total potassium (K), total nitrogen (N), total phosphorus (P), total sugar content (TSC), and proline content of the plants were determined. In addition, macro and microelement contents such as total N, extractable K, extractable magnesium (Mg), available P, available iron (Fe), and available manganese (Mn) of the study areas were determined. The highest concentrations of TSC (72.90mgkg-1 ± 3.87) and TN (0.265gkg-1 ± 0.021) of the plant, and also the highest extractable Mg (26.60mgkg-1 ± 1.70) and available Fe (0.44mgkg-1 ± 0.19), of soil were related to the Qavam Abad habitat. The highest concentrations of total K (17.495gkg-1 ± 4.91) and total P (1.206gkg-1 ± 0.257) of plants, and the highest extractable K (356.68gkg-1 ± 63.53) of soil belonged to the Tang Chenar Station. The highest TN content (6.3gkg-1 ± 1.21) of soil and the highest proline content (0.015gkg-1 ± 0.003) of plants was related to the Damgahan habitat. Also, the concentrations of soil available Mn and available P had the highest levels in the Damgahan (0.60gkg-1 ± 0.34) and Qavam Abad habitats (0.075gkg-1 ± 30.74), respectively. There was no significant difference between the amount of nutrients and soil elements in the studied stations (p < 0.05). There was a positive and significant correlation between the amount of soil TN and plant TN (Pvalues = 0.001, R2 = 0.87). An inverse and significant correlation was also observed between the amount of soil available P and plant total P (Pvalues = 0.014, R2 = - 0.72). This study highlights the various environmental controls over soil's physicochemical properties, which have significant implications for the management of soil nutrients.

Amphiphilic self-assembling peptides: formulation and elucidation of functional nanostructures for imaging and smart drug delivery.

The rational design of self-assembled peptide-based nanostructures for theranostics applications requires in-depth physicochemical characterization of the peptide nanostructures, to understand the mechanism and the interactions involved in the self-assembly, allowing a better control of the objects' physicochemical and functional properties for theranostic applications. In this work, several complementary characterization methods, such as dynamic light scattering, transmission electron microscopy, circular dichroism, Taylor dispersion analysis, and capillary electrophoresis, were used to study and optimize the self-assembly of pH-sensitive short synthetic amphiphilic peptides containing an RGD motif for active targeting of tumor cells and smart drug delivery. The combined methods evidenced the spontaneous formation of nanorods (L = 50nm, d = 10nm) at pH 11, stabilized by β-sheets. To complement with imaging properties for diagnosis, a new strategy was developed by designing an optimized peptide sequence to allow for efficient functionalization with a contrast agent, while preserving the self-assembling properties. Co-assemblies of the peptide and its derivatives, after peptide modification with a gadolinium complex, exhibited similar nanorod structures and required properties for drug delivery and imaging applications in vivo.

Regulated Li+ Solvation via Competitive Coordination Mechanism of Organic Cations for High Voltage and Fast Charging Lithium Metal Batteries.

Li+ solvation exerted a decisive effect on electrolyte physicochemical properties. Suitable tuning for Li+ solvation enabled batteries to achieve unexpected performance. Here, we introduced inert organic cations to compete with Li+ for combining electrolyte molecules to modulate Li+ coordination in the electrolyte. The relevance between the number of cationic sites in organic cations and the competitive solvation ability was explored. The organic cations with multiple cationic sites attracted solvent molecules and anions away from Li+ to form new solvated shell, improving the Li+ transport kinetics and desolvation process in electrolyte while enhancing electrolyte oxidation tolerance. Moreover, electrostatic shielding provided by organic cations and anion-derived robust SEI promoted uniform and rapid Li+ deposition on Li electrodes. With the positive effect of organic cations, Li||LiCoO2 (LCO) batteries showed high specific capacity (136.46 mAh g-1) at high charge/discharge rate (10 C). Furthermore, Li||LCO batteries exhibited good capacity retention (70% after 500 cycles) at 4.6 V charge cut-off voltage. This work provides fresh insights for the optimization of electrolytes and battery performance.

Isosteric 3D Bicyclo[1.1.1]Pentane (BCP) Core-Based Lipids for mRNA Delivery and CRISPR/Cas Gene Editing.

Lipid nanoparticles (LNPs) are an essential component of messenger RNA (mRNA) vaccines and genome editing therapeutics. Ionizable amino lipids, which play the most crucial role in enabling mRNA to overcome delivery barriers, have, to date, been restricted to two-dimensional (2D) architectures. Inspired by improved physicochemical properties resulting from the incorporation of three-dimensionality (3D) into small-molecule drugs, we report the creation of 3D ionizable lipid designs through the introduction of bicyclo[1.1.1]pentane (BCP) core motifs. BCP-based lipids enabled efficient in vivo mRNA delivery to the liver and spleen with significantly greater performance over 2D benzene- and cyclohexane-based analogues. Notably, lead BCP-NC2-C12 LNPs mediated ∼90% reduction in the PCSK9 serum protein level via CRISPR/Cas9 gene knockout, outperforming 2D controls and clinically used DLin-MC3-DMA LNPs at the same dose. Here, we introduce BCP-based designs with superior in vivo activity, thereby expanding the chemical scope of ionizable amino lipids from 2D to 3D and offering a promising avenue to improve mRNA and gene editing efficiency for the continued development of genetic medicines.

A Cheminformatics Workflow to Select Representative TSCA Chemicals for New Approach Methodology (NAM) Screening.

The Toxic Substances Control Act (TSCA) requires the US EPA to evaluate the hazard and exposure of new and existing chemicals. New chemical notifications are typically data-poor and EPA has historically relied upon approaches including chemical categories to fill data gaps. As part of a multi-year Research Program, opportunities are being explored to leverage New Approach Methods (NAMs) in hazard and exposure assessments. Data from a battery of in vitro NAMs will be generated to form a case study for an adaptable approach to inform new chemical assessments. Herein, a cheminformatics workflow was developed to identify a set of ∼300 representative candidate chemicals for in vitro screening from the TSCA non-confidential active inventory. The freely available web application ClassyFire was used to categorize all discrete organic structures from the TSCA inventory into one of 68 primary structural categories. Large primary categories were subcategorized into smaller categories using hierarchical agglomerative clustering, ultimately yielding 180 structural terminal categories. The inventory was filtered to substances that lacked previous ToxCast bioactivity screening, were associated with physicochemical property predictions indicating non-volatile solids or liquids, and had a higher chance of procurement. Amenability predictions for liquid chromatography-mass spectrometry were also generated to provide an indication of which chemicals lent themselves to aqueous-based screening and analytical verification in solvated samples. Structures associated with transformation in solvent, potentially explosive or highly reactive, were excluded. Potential candidate substances were selected on the basis of being structurally representative of the terminal category and meeting other screenability conditions. A final set of 318 candidate chemicals were proposed to undergo analytical quality control and screening in a range of broad and targeted biological technologies for human health-relevant end points. Finally, in silico tools were applied to explore predicted hazard profiles of these candidate substances relative to the full inventory.

Identification of novel tau positron emission tomography tracers for chronic traumatic encephalopathy by comprehensive in silico screening and molecular dynamics simulation.

Chronic traumatic encephalopathy (CTE), a neurodegenerative disease associated with repetitive mild traumatic brain injury, is characterized neuropathologically by abnormal hyperphosphorylated tau accumulation. Early detection of tau deposition in the brain is crucial for the prevention and evaluation of CTE. Positron emission tomography (PET) tracers can image specific proteins, while the optimal PET tracer for CTE tau fibrils remains unidentified. In this study, structure-based virtual screening and CNS PET MPO algorithms were utilized to identify candidates for novel tau PET tracers from 23 000 compounds in the ChemDiv CNS BBB library. A total of 8 μs molecular dynamics simulations were then employed to evaluate their binding affinity and atomic-level interaction with CTE tau protofibrils. The results indicate that V017-7820 (CNS-4), S776-0061 (CNS-12), S567-0465 (CNS-18), and T828-0465 (CNS-25) exhibit higher docking scores and binding free energies with CTE tau protofibrils while also satisfying the fundamental physicochemical properties of PET tracers. Further simulation analyses reveal that CNS-4 has the strongest binding affinity to tau protofibrils among the four compounds. Hydrophobic, π-π stacking, and hydrogen bonding interactions are the primary driving forces for the binding of these compounds to CTE tau protofibrils. In particular, CNS-12 and CNS-25 exhibit more intense hydrophobic and π-π stacking interactions, whereas CNS-4 and CNS-25 exhibit stronger hydrogen bonding interactions. This study identifies promising lead compounds for tau PET tracers and highlights their mechanism of binding to CTE tau protofibrils, which provides new insights for further screening and development of novel PET tracers for CTE diagnosis.

Nanoporous High Entropy Alloy Al-Pt-Pd-Ru as an Efficient Catalyst for One-Pot Reductive Amination of Nitroarenes.

High entropy alloys (HEAs) are promising heterocatalysts because of their unique physicochemical properties, but research on HEA-catalyzed tandem reactions is lacking. Moreover, limited research on HEAs for molecular transformation has hindered their development. Herein, an unsupported nanoporous HEA Al-Pt-Pd-Ru (HEANPore) prepared using a top-down dealloying method is reported. The Lewis acidity and electron redistribution of the noble metals Pt, Pd, and Ru are identified to be intrinsic of high activity and selectivity of HEANPore in the one-pot reductive amination of nitroarenes. The competitive adsorption of the reactant and corresponding reaction mechanism are investigated using DFT. This study demonstrates the exceptional performance of the HEANPore in tandem reactions, presenting new possibilities for the application of HEAs in the field of catalysis.

Nanoparticles with "K-edge" Metals Bring "Color" in Multiscale Spectral Photon Counting X-ray Imaging.

Preclinical and clinical diagnostics depend greatly on medical imaging, which enables the identification of physiological and pathological processes in living subjects. It is often necessary to use contrast agents to complement anatomical data with functional information or to describe the disease phenotypically. Nanomaterials are used as contrast agents in many advanced bioimaging techniques and applications because of their high payload, physicochemical properties, improved sensitivity, and multimodality. Metals with k-edge energy within the X-ray bandwidth respond to photon counting and spectral X-ray imaging. This Perspective examines the progress made in the emerging area of nanoparticle-based k-edge contrast agents. These nano "k-edge" particles have been explored with spectral photon counting CT (SPCCT) for multiplexed molecular imaging, pushing the boundaries of resolution and capabilities of CT imaging. Design considerations, contrast properties, and biological behavior are discussed in detail. The key applications are highlighted by categorizing these nanomaterials based on their X-ray, k-edge energy, and biological properties, as well as their synthesis, functionalization, and characterization processes. The article delves into the transformative impact of nano "k-edge" particles on early disease detection and other biomedical applications. The review provides further insights into how the "k-edge signatures" of these nanoparticles combined with photon counting technique can be leveraged for quantitative, multicontrast imaging of diseases. We also discuss the status quo of clinically approved nanoparticles for imaging and highlight the challenges such as toxicity and clearance as well as promising clinical perspectives, providing a balanced view of the potential and limitations of these nanomaterials. Furthermore, we discuss the necessary future research efforts required to clinically translate nano "k-edge" particles as SPCCT contrast agents for early disease diagnosis and tracking.

RECEIVING AND ADSORPTION CHARACTERISTICS OF BIOCARBON MATERIALS FROM HOUSEHOLD WASTE

The aim of this research is the development of new carbon materials based on agricultural waste and a detailed study of their physicochemical properties, which allows to evaluate the potential directions of use of these materials in industry and environmental technologies. Within the framework of the work, four types of waste were chosen, in particular, wood sawdust, apple cake, as well as wheat and corn husks, which are widely available and rarely used as raw materials for creating adsorbents. The selected materials were subjected to the process of pyrolysis at a temperature of 500°C for one hour, which effectively preserves the porous structure of the material and improves its adsorption properties. The obtained samples of biocarbon materials were analyzed using nitrogen porosimetry, which made it possible to determine their adsorption potential, porosity, and total surface area. The results of the study showed a significant difference in the adsorption capacity of the samples, depending on the type of raw material. The sample based on corn husk demonstrated the highest adsorption activity, which indicates its potential for water purification from various types of pollution, including organic and inorganic compounds, heavy metals and other toxic substances. In addition, an additional analysis of the samples was carried out in order to assess their potential in other industries. In particular, the revealed porosity and surface area of ​​the materials allow us to consider them as promising components for filtration systems, catalysts in chemical reactions, materials for energy storage, as well as means for environmental protection and environmental restoration. The results of the study confirm that the use of agricultural waste for the creation of functional carbon materials is not only economically beneficial, but also an ecologically appropriate approach, which contributes to reducing the amount of waste and creating new opportunities for sustainable development.

Effect of Opuntia ficus-indica Extract in Pro-Healthy Chicken Patties: Physicochemical Properties and Oxidative Stability

Opuntia ficus-indica is a subtropical fruit rich in dietary fibers, carotenoids, vitamins, minerals, and polyphenols. To substitute synthetic additives, its extracts could become an interesting proposal to preserve quality while adding desirable characteristics to meat products. This study aimed to develop healthier chicken patties (with a structured animal fat replacer) added with prickly pear extract (PPE). The extract was analyzed for total phenolic content and antioxidant activity (FRAP, ABTS, DPPH, and ORAC). Four chicken patty formulations were manufactured with total replacement of animal fat by sesame oil emulsion: control, erythorbate 500 ppm, PPE 500, and PPE 750 ppm. Proximate composition and fatty acid profile were analyzed on day 1, and pH, color, and lipid oxidation on days 1, 4, 8, 12, and 16. PPE treatments showed lower TBARSs (p &lt; 0.05) and greater pigment stability at the end of storage, corroborating its potential to delay oxidation reactions. No significant effects on chemical composition, pH, or fatty acid profile were observed (p &gt; 0.05). Unsaturated represented 76.2% of total fatty acids. Therefore, PPE is an effective antioxidant by improving oxidative stability without promoting changes in other properties, besides adding cleaner label approaches and the use of natural ingredients to develop meat products reformulated with unsaturated oils.

Current Advances in Viral Nanoparticles for Biomedicine.

Viral nanoparticles (VNPs) have emerged as crucial tools in the field of biomedicine. Leveraging their biological and physicochemical properties, VNPs exhibit significant advantages in the prevention, diagnosis, and treatment of human diseases. Through techniques such as chemical bioconjugation, infusion, genetic engineering, and encapsulation, these VNPs have been endowed with multifunctional capabilities, including the display of functional peptides or proteins, encapsulation of therapeutic drugs or inorganic particles, integration with imaging agents, and conjugation with bioactive molecules. This review provides an in-depth analysis of VNPs in biomedicine, elucidating their diverse types, distinctive features, production methods, and complex design principles behind multifunctional VNPs. It highlights recent innovative research and various applications, covering their roles in imaging, drug delivery, therapeutics, gene delivery, vaccines, immunotherapy, and tissue regeneration. Additionally, the review provides an assessment of their safety and biocompatibility and discusses challenges and future opportunities in the field, underscoring the vast potential and evolving nature of VNP research.

Propane dehydrogenation over silicalite‐1 supported PtMn catalyst with low Pt loading

Pt‐based catalysts have been widely studied for propane dehydrogenation (PDH) because of their high activity and environmental sustainability. However, as a precious metal, the development of catalysts with high stability and low Pt content is of great significance. In this study, a series of silicalite‐1‐supported PtMn (0.1PtxMn/S‐1) catalysts with low Pt loading amount (0.1 wt%) was prepared. The effects of different Mn loadings on the physicochemical properties and catalytic performance in the PDH reaction were studied. The addition of an appropriate amount of Mn regulated the dispersion of Pt particles and increased the number of active sites of the catalyst, enhancing the catalytic performance of PDH even at a low Pt loading. The initial propane conversion was 46.1% over 0.1Pt0.3Mn/S‐1 catalyst, and the deactivation rate constant was the lowest of 0.010 h‐1. This may be because an appropriate Mn loading was beneficial for enhancing the interaction between the metal and the support, forming MnOx attached to the S‐1 surface, while the surface of MnOx stabilized the PtMn alloy, thereby improving the catalytic performance for PDH.

Physico-chemical, textural, microbiological and sensory properties together with fatty acid profiles of presumptive probiotic yoghurts fortified with persimmon (Diospyros kaki) powder.

This research paper focuses on enrichment of yoghurt containing probiotic Lactobacillus casei with persimmon (Diospyros kaki) powder in concentrations of 0 (Control) and then 0.5, 1.0, 1.5 and 2.0% (A-D respectively) and determination of some characteristics of the product during refrigerated storage for 21 d. Powder addition affected the color characteristics, textural properties, titratable acidity and water-holding capacity values. The viability of both yoghurt bacteria (Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus) and L. casei increased proportionally to adding persimmon powder for all storage days. Furthermore, addition of fruit powder increased short-chain fatty acid and polyunsaturated fatty acid contents. According to sensory analysis results, sample D had the lowest scores from the panelists, whereas the Control together with samples B and C were the most liked yoghurts in terms of flavor characteristics. In terms of overall acceptability, all of the samples received scores over three points on a five-point scale throughout storage. This study indicates that persimmon powder enriched yoghurt is a good vehicle for L. casei and yoghurt bacteria with improved fatty acid profile and acceptable sensory characteristics.

Investigation of drying kinetics, nutrient profile, physicochemical and functional properties of purple yam (Dioscorea alata) under different drying conditions

Investigation of drying kinetics, nutrient profile, physicochemical and functional properties of purple yam (Dioscorea alata) under different drying conditions

New Insights into Red and White Quinoa Protein Isolates: Nutritional, Functional, Thermal Properties

Quinoa (Chenopodium quinoa Willd.) seeds, renowned for their nutritional richness and balanced amino acid profile, offer promising potential as food ingredients. This study focused on extracting and characterizing the protein isolates from red and white quinoa varieties to evaluate their physicochemical and functional properties. Protein isolation involved alkaline solubilization and isoelectric precipitation, followed by characterization through amino acid analysis, phenolic profiling, scanning electron microscopy (SEM), zeta potential measurement, particle size distribution analysis, Differential Scanning Calorimetry (DSC), and rheological studies. The results showed that both the red and white quinoa protein isolates exhibited high protein content and essential amino acids, with notable differences in their amino acid compositions. The phenolic and flavonoid content varied between the red and white quinoa seeds, highlighting their potential antioxidant properties. SEM revealed distinct microstructural differences between the red and white quinoa protein isolates. Zeta potential measurements indicated the negative surface charges, influencing the stability in the solution. A particle size distribution analysis showed the monomodal distributions with minor variations in the mean particle size. The DSC profiles demonstrated multiple denaturation peaks, reflecting the complex protein compositions. Rheological studies indicated diverse gelation behaviors and mechanical properties. Overall, this comprehensive characterization underscores the potential of quinoa protein isolates as functional food ingredients with diverse applications in the food industry.

High-throughput near-infrared spectroscopy for detection of major components and quality grading of peas

Pea (Pisum sativum L.) is a nutrient-dense legume whose nutritional indicators influence its functional qualities. Traditional methods to identify these components and examine the relationships between their contents could be more laborious, hindering the quality assessment of the varieties of peas. This study conducted a statistical analysis of data about the sensory and physicochemical nutritional attributes of peas acquired using traditional techniques. Additionally, 90 sets of spectral data were obtained using a portable near-infrared spectrometer, which were then integrated with chemical values to create a near-infrared model for the basic ingredient content of peas. The correlation analysis revealed significant findings: pea starch displayed a substantial negative correlation with moisture, crude fiber, and crude protein, while showing a highly significant positive correlation with pea seed thickness. Furthermore, pea protein exhibited a significant positive correlation with crude fiber and crude fat. Cluster analysis classified all pea varieties into three distinct groups, successfully distinguishing those with elevated protein content, high starch content, and low-fat content. The combined contribution of PC1 and PC2 in the principal component analysis (PCA) was 51.2%. Partial least squares regression (PLSR) and other spectral preprocessing methods improved the predictive model, which performed well with an external dataset, with calibration coefficients of 0.89–0.99 and prediction coefficients of 0.71–0.88. This method enables growers and processors to efficiently analyze the composition of peas and evaluate crop quality, thereby enhancing food industry development.

An Evaluation of the Effects of Pepper (Zanthoxylum bungeanum Maxim.) Leaf Extract on the Physiochemical Properties and Water Distribution of Chinese Cured Meat (Larou) During Storage

In this study, pepper (Zanthoxylum bungeanum Maxim.) leaf (ZL) extract was added to larou to investigate the improvement in the quality of physicochemical properties, texture, water distribution, and microorganism growth during storage for 20 days. Based on the results, the addition of ZL extract significantly retarded the increase in cooking loss, TBARS value, hardness, and microorganism growth. Moreover, the addition of ZL extract decreased the pH value, lightness, and microorganism counts, and increased the moisture content, total soluble protein content, a* value, b* value, and chewiness. The LF-NMR results showed that the addition of ZL extract shortened the T2 relaxation time and boosted the proportion of immobilized water, facilitating the validation of the improvement in water retention of larou during storage. The FT-IR results indicated that the addition of ZL extract influenced the protein secondary structure by inducing the conversion of α-helices to β-sheet structures. Accordingly, ZL extract has the potential to serve as a natural antioxidant, effectively helping to ameliorate the quality properties of cured meat products during storage.

Responses of Soil Infiltration and Erodibility to Vegetation Succession Stages at Erosion and Deposition Sites in Karst Trough Valleys

The topographies of soil erosion and deposition are critical factors that significantly influence soil quality, subsequently impacting the erodibility of soils in karst regions. However, the investigation into the effects of erosion and deposition topographies on soil erodibility across different stages of vegetation succession in karst trough valleys is still at a preliminary stage. Therefore, three distinct topographic features (dip slopes, anti-dip slopes, and valley depressions) were selected at erosion (dip/anti-dip slope) and deposition sites (valley) to investigate the spatial heterogeneity of soil physicochemical properties, infiltration capacity, aggregate stability, and erodibility in karst trough valleys. Additionally, five different stages of vegetation succession in karst forests were considered: Abandoned land stage (ALS), Herb stage (HS), Herb-Shrub stage (HES), Shrub stage (SHS), and Forest stage (FS). Additionally, the relationships among these factors were analyzed to identify the key driving factors influencing soil erodibility. The results revealed that soil physicochemical properties and soil aggregate stability at the deposition site were significantly superior to those at the erosion site. The FS resulted in the best soil physicochemical properties, whereas the HS resulted in the highest soil aggregate stability within the deposition site. However, the soil infiltration capacity at the erosion site was significantly greater than that at the deposition sites. The ALS had the strongest soil infiltration capacity at both the erosion and deposition sites. The soil erodibility at erosion sites (0.064) was significantly greater than that at deposition sites (0.051), with the highest soil erodibility observed on anti-dip slopes during the HES at erosion sites (0.142). The structural equation model reveals that erosion and deposition topographies, vegetation succession, soil physicochemical properties, soil aggregates, and soil infiltration characteristics collectively account for 88% of the variation in soil erodibility under different conditions. Specifically, both direct and indirect influences on soil erodibility are most significantly exerted by soil aggregate stability and vegetation succession. This study provides scientific evidence to support the management of soil erosion and ecological restoration in karst trough valleys while offering technical assistance for regional ecological improvement and poverty alleviation.