Peter Black Research Articles

CPD: Myopia management update part 2

Following on from their recent article Myopia management with spectacle lenses – an update (Optician July 28, 2023) – Peter Black and Tina Arbon Black explore myopia evidence, new management options and some of the standards of practice issues that surround myopia management

CPD: Myopia management with spectacle lenses - an update

Peter Black and Tina Arbon Black refresh our memories about the spectacle correction of myopia and bring us up to date with the latest developments in myopia management lens designs (C106065, suitable for logging as one provider-led distance learning CPD point for optometrists and dispensing opticians)

MP44-12 mpMRI-TARGETED BIOPSY COMPARED TO SYSTEMATIC TRUS BIOPSY FOR MEN AT RISK FOR PROSTATE CANCER: 2 YEAR FOLLOW UP DATA AND ECONOMIC ANALYSIS

You have accessJournal of UrologyCME1 Apr 2023MP44-12 mpMRI-TARGETED BIOPSY COMPARED TO SYSTEMATIC TRUS BIOPSY FOR MEN AT RISK FOR PROSTATE CANCER: 2 YEAR FOLLOW UP DATA AND ECONOMIC ANALYSIS Laurence Klotz, Joseph Chin, Peter Black, Antonio Finelli, Maurice Anidjar, Marlene Kebabdjian, Nicole Mittmann, and Soo Jin Seung Laurence KlotzLaurence Klotz More articles by this author , Joseph ChinJoseph Chin More articles by this author , Peter BlackPeter Black More articles by this author , Antonio FinelliAntonio Finelli More articles by this author , Maurice AnidjarMaurice Anidjar More articles by this author , Marlene KebabdjianMarlene Kebabdjian More articles by this author , Nicole MittmannNicole Mittmann More articles by this author , and Soo Jin SeungSoo Jin Seung More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003290.12AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The Precise study, a prospective randomized trial, demonstrated that MRI with only targeted biopsy was non-inferior to systematic TRUS guided biopsies in the detection of GG ≥2 PCa. An unanswered question is the outcome in those patients who avoided a biopsy due to a negative MRI.We addressed the outcome of patients on this trial who were unbiopsied, or had a negative or GG1 targeted biopsy, compared to those whose systematic biopsy was negative or GG1, with respect to the rate of subsequent prostate cancer diagnosis based on a 2 year MRI performed in all patients. In addition, we used administrative provincial data to compare the net costs of systematic biopsy vs MRI and targeted biopsy. METHODS: The study was carried out at 5 Canadian centres. The Precise trial accrued 453 biopsy-naïve men with a clinical suspicion of PCa advised to have a prostate biopsy. All those not initially diagnosed with GG≥2 PCa (unbiopsied due to a negative MRI, or a negative biopsy, or GG1 disease if biopsied) were entered in the follow up study. All Ontario patients were entered in the economic analysis. The intervention was an MRI at year 2 in all men in both MRI and systematic biopsy groups. Biopsy was performed for PiRads ≥ 3 or clinical suspicion. RESULTS: 73 patients in the MRI arm and 69 patients in the systematic biopsy arm had a 2 year evaluable MRI. In the MRI and syst bx arm, 70% and 72% had a negative 2 year MRI. Of the 16 patients in the systematic biopsy arm who had a 2 year biopsy, 8 were negative, 2 were GG1, and 6 were GG ≥2. In the MRI arm, 8 were biopsied; 4 were negative, and 4 were GG ≥2. At 2 years, in the Syst Bx and MRI groups, 27% and 30% either were diagnosed with GG≥2. disease; treated, died, or progressed. 15% from the TRUS biopsy group had a hospital visit after biopsy compared to less 6% from the MRI+ group. The mean per person per year (PPPY) costs for the TRUS and All MRI groups (MRI- and MRI+) were $7,828 and $8,525, respectively. CONCLUSIONS: After 2 years of follow up including an MRI in all patients, there was no difference in the rate of CS Pca diagnosis between the MRI with only targeted biopsy and systematic biopsy groups, despite 40% of men in the MRI group avoiding biopsy. These patients will be followed for an additional 6 years to confirm this finding. Economic analysis using a linked provincial databased demonstrated no significant difference in net cost between the 2 strategies. This data reinforces that an imaging first diagnostic strategy is safe and cost-effective. ClinicalTrials.gov Identifier: NCT02936258 Source of Funding: This study was co-funded by the OICR, and Prostate Cancer Canada © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e616 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Laurence Klotz More articles by this author Joseph Chin More articles by this author Peter Black More articles by this author Antonio Finelli More articles by this author Maurice Anidjar More articles by this author Marlene Kebabdjian More articles by this author Nicole Mittmann More articles by this author Soo Jin Seung More articles by this author Expand All Advertisement PDF downloadLoading ...

MP59-14 CROSS-SECTIONAL STUDY ASSESSING UTILIZATION PATTERNS OF COMBINATION INTRAVESICAL GEMCITABINE AND DOCETAXEL IN THE MANAGEMENT OF BLADDER CANCER

You have accessJournal of UrologyCME1 May 2022MP59-14 CROSS-SECTIONAL STUDY ASSESSING UTILIZATION PATTERNS OF COMBINATION INTRAVESICAL GEMCITABINE AND DOCETAXEL IN THE MANAGEMENT OF BLADDER CANCER Andrew Gabrielson, Sunil Patel, Noah Hahn, Angela Smith, Eugene Pietzak, Peter Black, Trinity Bivalacqua, and Max Kates Andrew GabrielsonAndrew Gabrielson More articles by this author , Sunil PatelSunil Patel More articles by this author , Noah HahnNoah Hahn More articles by this author , Angela SmithAngela Smith More articles by this author , Eugene PietzakEugene Pietzak More articles by this author , Peter BlackPeter Black More articles by this author , Trinity BivalacquaTrinity Bivalacqua More articles by this author , and Max KatesMax Kates More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002642.14AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Intravesical bacillus-calmette Guerin (BCG) is a mainstay treatment of non-muscle invasive bladder cancer (NMIBC), however BCG therapy is fraught with frequent drug shortages and its scarcity has prompted investigation into alternative agents. Intravesical gemcitabine and docetaxel (GemDoce) is a safe therapy for BCG-unresponsive NMIBC and BCG naïve NMIBC in times of BCG shortage with efficacy approaching BCG in retrospective series. We sought to assess utilization and barriers to administration of GemDoce to inform accrual for a phase 3 randomized trial. METHODS: A cross-sectional, web-based survey was distributed via the Society of Urologic Oncologists (SUO) and Canadian Urologic Oncology Group (CUOG) mailing lists using Google Forms. Provider prescribing patterns including the preferred setting of GemDoce use, annual prescribing rate, and description of barriers to administration of GemDoce were assessed. RESULTS: The survey was distributed to 982 addresses (661 report bladder cancer in their practice). A total of 198 participants completed the survey (30% response rate for target audience), of which 141 (71%) endorsed prescribing GemDoce over the last 12 months. The most common indication was BCG-unresponsive NMIBC +/- CIS (67%), followed by primary treatment of high-risk NMIBC (25%) and primary treatment of intermediate-risk NMIBC (15%). Based on conservative estimates of participant responses, at least 1,300 patients within the practices of the surveyed urologists are being prescribed GemDoce for NMIBC on an annual basis. Notably, 44% of participants endorsed at least one barrier to prescribing or administering GemDoce at their institution. Common barriers included problems with clinical workflow (i.e. clinic space to administer drug), challenges with hospital pharmacies supplying the drug, challenges with identifying who would benefit most from this regimen, and cost (Figure 1). CONCLUSIONS: Results from this cross-sectional web-based survey demonstrate that GemDoce is being widely utilized among urologic oncologists for several disease states of NMIBC. Several barriers exist that may hinder use of GemDoce and future clinical trial designs will need to account for these potential challenges in clinical workflow. Source of Funding: N/A © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e1007 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Andrew Gabrielson More articles by this author Sunil Patel More articles by this author Noah Hahn More articles by this author Angela Smith More articles by this author Eugene Pietzak More articles by this author Peter Black More articles by this author Trinity Bivalacqua More articles by this author Max Kates More articles by this author Expand All Advertisement PDF DownloadLoading ...

Fundamentals of ophthalmic dispensing 25: Presbyopia 3 – Progressive-power lenses

In this the third article in this series concentrating on correction of presbyopia Peter Black and Tina Arbon Black take a look at progressive-power lenses.

Dispensing interactive 1

In the first of a series of interactive exercises aimed at encouraging discussion about dispensing skills, Peter Black describes a case of intolerance to a recently dispensed pair of progressive power lenses.

Fundamentals of ophthalmic dispensing 23: Presbyopia 2

Modern presbyopes have a huge selection of vision correction options from which to choose. In this article Tina Arbon Black and Peter Black discuss the ‘old-fashioned’ options of two separate pairs and segmented lenses which still have an important place in the optician's armoury.

Fundamentals of ophthalmic dispensing 23: Presbyopia 1

In the first of two articles, Peter Black and Tina Arbon Black discuss explain the phenomenon of presbyopia and look at the challenges it presents when dispensing an appropriate correction.

Fundamentals of ophthalmic dispensing 22: Contact lens regulations

Tina Arbon Black and Peter Black discuss the basics of contact lenses and the regulations relating to their supply.

Fundamentals of ophthalmic dispensing 20: Personal eye protection 1

Eye injury remains a significant cause of monocular visual impairment, and blindness in monocular patients. This is the first of two articles in which Peter Black and Tina Arbon Black explore personal eye protection and prescription safety spectacles. (C78821 suitable as one distance learning CET point for optometrists and dispensing opticians)

Fundamentals of ophthalmic dispensing 19: Paediatric dispensing

Because of the potential to do harm, paediatric dispensing is a key skill and core competency for all dispensing opticians and optometrists – especially those that supervise others and ‘sign off’ children's spectacles dispensing. Here Tina Arbon Black and Peter Black cover the essentials of the art, science and legalities of dispensing to children.

Fundamentals of ophthalmic dispensing 18: Law and regulation – part 1

The sale of optical appliances is governed partly by ordinary consumer legislation and specifically through the Opticians Act and the various orders of the General Optical Council. Here Tina Arbon Black and Peter Black take a look at the legislation, regulations and standards that apply to ophthalmic dispensing.

Fundamentals of ophthalmic dispensing – part 17 Visual task analysis – part 3

In this third article on visual task analysis Peter Black and Tina Arbon Black look at dispensing solutions to the visual problems in the real world of work, home and leisure activities, concentrating principally on outdoor tasks including aspects of regulations and standards relating to sports, health and safety and driving.

Fundamentals of ophthalmic dispensing part 16: Visual task analysis – part 2

In this second article on visual task analysis Peter Black and Tina Arbon Black look at dispensing solutions to the visual problems in the real world of work, home and leisure activities including aspects of regulations and standards relating to health & safety, display screen equipment and driving.

Fundamentals of ophthalmic dispensing part 15: Visual task analysis – part 1

At its simplest level a visual task analysis can be considered an assessment of the interaction between a patient, their optical appliance and the visual elements of their environment – the things they are trying to see and do. In this, the first of two articles, Peter Black introduces the topic and tackles the often confusing subject of photometry bringing it up to date for a world illuminated by low energy light bulbs.

William Hogarth (1697–1764) and book illustration I: Hudibras, Quixote and the Littlecote House murals

This article progresses long-term researches on Hogarth and book history, the iconography of the skimmington and transnational receptions of Don Quixote, by introducing a substantial new group of images potentially illuminating Hogarth's lost activities as a young painter, before he turned 30 in 1727. Astoundingly, no previous research-based study of them exists. Unknown to Hogarth specialists and dismissed by art historians, they are in the painted room at Littlecote House. Within a complex decorative scheme broadly referencing themes of human folly and the cabinet of curiosities, two walls feature floor to ceiling composite murals uniting numerous episodes from the publications most significant for Hogarth's early career as a book illustrator: Cervantes' Don Quixote and its most successful English derivation, Samuel Butler's Hudibras. Butler's book-length poem is exceptionally significant: Book-historically for its key role in copyright legislation and eighteenth-century British book illustration; arthistorically for its central role in the early career of Hogarth, who published two sets of engravings illustrating Hudibras in 1726. Local historians attribute the Littlecote murals to unidentified amateur Dutch painters, working in the 1660s (when Hudibras was first published). Archive-based evidence first presented here confirms their dating not to the 1660s but the 1720s and supports Hogarth's presence at Littlecote House around 1724. This work is heavily indebted to the exemplary scholarship of two landmark publications of 2016, Elizabeth Einberg's authoritative catalogue of Hogarth's paintings (all post-1726) and Peter Black's ground- -breaking exploration of Hogarth and house decoration. I here re-visit Hogarth's early practice of book illustration and house decoration with reference to a canon of pre-1800 Hudibras images, newly enlarged by situating the substantial Littlecote Hudibras mural within this context and its associated visual, literary and book historical traditions. With reference to the new images and evidence first presented here, I ask: Is Littlecote's painted room a rightly neglected pastiche? Or does it deserve closer scholarly attention? Perhaps even as an exceptional unrecognized British art treasure? Should Hogarth specialists now evaluate an entirely new possibility: whether the challenging pre-1727 gap in Hogarth's early career as a painter can be addressed by identifying his earliest paintings at Littlecote House? I must confess, I have but little hopes of having a favourable attention given to my design in general, by those who have already had a more fashionable introduction into the mysteries of the arts of painting, and sculpture. Much less do I expect, or in truth desire, the countenance of that set of people, who have an interest in exploding any kind of doctrine, that may teach us to see with our own eyes.

Fundamentals of ophthalmic dispensing 14: Prismatic effects and binocular vision – part 3

The preceding two articles in this series have looked at the basics of prismatic effects, binocular vision and eye movements. Here Peter Black and Tina Arbon Black apply that knowledge to common dispensing problems as well as introducing aspects of binocular vision in near vision (C76988, one distance learning CET point suitable for optometrists and dispensing opticians).

Fundamentals of ophthalmic dispensing part 13: Eye movements

In the second article focusing on binocular vision as an influence upon spectacle correction, Peter Black and Tina Arbon explain the anatomical basis of eye movement and how each eye moves relative to the other (C76782, one distance learning CET point suitable for optometrists and dispensing opticians)

Prismatic effect and binocular vision basics – part 1

In the first of two articles looking at prisms, both prescribed and induced, Peter Black and Tina Arbon Black offer a revision of some core aspects of eye movements and binocular vision and the purpose and production of prescribed prism (C76568, one distance learning CET point suitable for optometrists and dispensing opticians)

Fundamentals of ophthalmic dispensing – part 11: Single vision lens design part 2

In the second of their discussions of single vision lens design, Peter Black and Tina Arbon Black take a look at single vision aspheric and reduced aperture lens forms and consider related practical dispensing issues including field of view (C 76149, one distance learning CET point suitable for optometrists and dispensing opticians)