The indispensable role that transnational corporations play as vehicles of foreign investment and economic development cannot be overemphasized. Developing countries, of which Nigeria is one, understand the impact of the activities of these corporations on their economic growth and development. However, weak institutions and poor regulatory framework on the part of the host country have resulted in grave violation of human rights (civil and environmental). This article examines the litigation of these human right abuses by transnational corporations from the perspective of the Nigerian victims. It does not attempt to be an exhaustive discussion of the hypothesis; however, it looks at some significant cases that define the quest for justice by these victims. It concludes with a verdict that the answer to the problem of abuse of human rights lies in the strengthening of relevant regulatory institutions in Nigeria.