Personality Inventory For DSM-5 Brief Form Research Articles

The Personality Inventory for DSM-5-Brief Form (PID-5-BF): Psychometric indicators in a Brazilian community sample

Objective: To investigate psychometric properties (internal structure, convergent/discriminant validity, internal consistency, and test-retest) of the Personality Inventory for DSM-5-Brief Form (PID-5-BF) in a Brazilian community sample. Method: This is a study with a psychometric design. A sample of 527 adults from the general population (69.9% women; 33.5 ± 14.0 years; 74.0% ≥ 12 years education) responded to the instrument online after the study was disseminated on social networks and to the researchers’ contacts. The NEO-PI-R and sociodemographic questionnaire were applied besides the PID-5-BF, and a retest was applied 15-30 days after the initial assessment for reliability assessment. Data were analyzed using statistical techniques (IBM SPSS19 and Factor20); the significance level was set at p ≤ 0.05 for all the analyses. Results: Internal consistency was verified using Cronbach’s alpha and was adequate (domains α ≥ 0.69; total α = 0.87), in addition to test-retest reliability (domains ICC ≥ 0.82; total ICC = 0.95). Divergences were found between the PID-5-BF different domains despite them being significantly correlated with each other. Convergent validity with the NEO-PI-R was adequate, with moderate/strong correlations between the domains theoretically associated (r > 0.38). The internal structure (Exploratory Factor Analysis) indicated that the original five-factor model (CFI = 0.991; TLI = 0.986; RMSEA = 0.033) and one-factor model were adequate (CFI = 0.908; TLI = 0.899; RMSEA = 0.089. Conclusions: The findings support using the PID-5-BF Brazilian version, which presented adequate psychometric properties comparable to the original version. This instrument can be helpful in the clinical and research fields to screen general and specific traits of personality pathology. Future studies are suggested to expand the psychometric findings among clinical samples, confirming the instrument’s scope of reach.

Gender Differences in the Relationship between Lifetime Exposure to Trauma and the Development of Pathological Personality Traits

ABSTRACT Gender differences in the prevalence, types and outcomes of traumas have consistently been reported in the literature. Other research has documented that exposure to trauma is associated with the development and maintenance of pathological personality traits. In the current study, we examined the moderating role of gender in the association between lifetime exposure to trauma and pathological personality traits. The sample included 148 clients who sought treatment at a community mental health clinic. All participants completed online questionnaires including demographic information, the Trauma History Questionnaire (THQ), and the Personality Inventory for DSM-5-Brief Form (PID-5-BF) at the entry to treatment. Our findings documented a significant association between exposure to trauma and pathological personality traits in men, but not in women. Furthermore, this pattern of results was specifically evident within two personality domains: antagonism and detachment. These findings contribute to the theoretical understanding of the interplay between trauma, gender, and the development of pathological personality traits. They expand upon the growing knowledge about the mental health crisis among boys and men by shedding light on the unique vulnerabilities that men face in response to traumatic experiences and how these experiences can have a lasting impact on their adaptive functioning. Consequently, at the clinical level, the current study emphasizes the importance of paying particular attention to men’s trauma histories and explicitly exploring these during the intake session.

Associating Internalizing and Externalizing Symptom Features With the Personality Inventory for DSM-5 Brief Form (PID-5-BF) in a Large Community Sample.

The Personality Inventory for DSM-5-Brief Form (PID-5-BF) is a relatively novel measure assessing maladaptive personality traits. We examined whether PID-5-BF traits are associated with non-personality measures of wellbeing in N = 661 Canadian adults in the community. Depression, anxiety, and perceived stress measures were obtained, as were indices of alcohol and cannabis use. Symptoms of depression and perceived stress were associated with all PID-5-BF dimensions, except for antagonism. Anxiety symptoms were associated with negative affectivity (NA) and, to a lesser extent, psychoticism. A younger age and female sex were related to higher depression and stress scores. In contrast to the models assessing depressive, anxiety and stress symptoms, in which NA was the strongest contributor, no significant contribution of internalizing traits (i.e., PID-5-BF NA) on substance use outcomes was found when externalizing traits were included in the models. Specifically, binge drinking and cannabis use were associated with higher disinhibition scores and lower psychoticism scores. Regression models were substantially weaker for substance use than for the mood and stress symptoms. Younger individuals used more cannabis and males engaged in more binge drinking. These findings largely confirm PID-5-BF's construct validity, and indicate that various indices of wellbeing (not necessarily personality-associated measures) are associated with personality traits, as measured with the brief from of PID-5-BF.

Gender and maladaptive personality correlates in problem gambling and over-indebtedness: Novel findings from a cross-sectional study in Sweden

Although most individuals consider gambling to be an innocent and fun activity, when it develops into problem gambling, it can have detrimental outcomes to one's life, such as over-indebtedness. This cross-sectional study explores the role of maladaptive personality traits and gender in both problem gambling and over-indebtedness, in an online sample of 1479 adult gamblers (65% males) in Sweden. Participants were administered the Problem Gambling Severity Index (PGSI), the Personality Inventory for DSM-5-Brief Form (PID-5-BF), and questions addressing subjective over-indebtedness and other risk factors. Quasi-Poisson loglinear models and logistic regression analyses demonstrated that Disinhibition (OR = 1.38, 95% CI [1.24, 1.53]), and Antagonism (OR = 1.23, 95% CI [1.14, 1.34]) showed the strongest associations to problem gambling, and that only Disinhibition (OR = 1.72, 95% CI [1.22, 1.43]) and Antagonism (OR = 2.00, 95% CI [1.52, 2.66]) were significantly related to over-indebtedness. The prevalence of problem gambling and over-indebtedness was more common among women, and gender moderated the univariate relationships of Negative Affectivity, Disinhibition and Psychoticism to problem gambling. These findings call for future research addressing maladaptive personality traits, problem gambling and over-indebtedness, and highlight the need for tailored interventions and prevention strategies, particularly for women who may be at higher risk.

Personality inventory for DSM–5-Brief Form (PID-5-BF): Measurement invariance across men and women.

The study examined the measurement invariance (configural, metric, scalar, and residual) of the Personality Inventory for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) Brief Form (PID-5-BF; Krueger et al., 2013) across gender for the theorized Five-Factor oblique model. A large group of adults (N = 502), with ages ranging from 18 to 67 years, from the Australian general community completed the PID-5-BF. When the Δχ² test was applied, multiple-group confirmatory factor analysis supported configural invariance and full metric and residual invariance. For scalar invariance, at least seven items (constituting 13 thresholds) across the different dimensions lacked invariance for one or more of its thresholds. In addition, controlling all these noninvariance thresholds, women had higher latent mean scores for Negative Affect, and men had higher scores for Antagonism and Disinhibition. When the Δcomparative fit index (ΔCFI) test was applied, the findings also supported the configural invariance model and the full metric and residual invariance models. With the exception of one threshold, all the other thresholds were also invariant. The psychometric and practical implications of the findings are discussed. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

Is there a bias in the diagnosis of borderline personality disorder among racially minoritized patients?

Empirical evidence documents disparities in the diagnosis of severe forms of psychopathology among racial/ethnic minority persons. However, research on diagnostic differences in personality disorders is equivocal: Some suggest higher prevalence of personality disorders among racial/ethnic minority persons, whereas other results suggest the opposite. The goal of the current study was to investigate (a) differences in the diagnosis of borderline personality disorder (BPD) in a mostly cisgender, heterosexual sample among racial/ethnic minority patients compared with non-Hispanic White patients and (b) whether any observed differences were attributable to differences in underlying maladaptive personality domains. Using data from partial hospital patients (N = 2,657), we found few differences in the diagnosis of BPD based on racial/ethnic group membership. We also conducted measurement invariance analyses of the Personality Inventory for DSM-5-Brief Form (PID-5-BF), finding evidence of invariance across White and non-White participants in these data. Any instances of diagnostic disparity were explained by group differences in maladaptive personality domains. These results provide context to the extant literature documenting mixed results about racial/ethnic differences in prevalence of personality disorders. In addition, they suggest relative specificity in BPD diagnostic bias related to sexual minority populations. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Associations between physical health and the alternative model of personality disorders: A cross-sectional age study.

The Alternative Model of Personality Disorders (AMPD) is a relatively new dimensional model of personality disorders (PDs) that assesses two diagnostic constructs: personality functioning and pathological personality traits. Thus far, research on the AMPD among older adults has been limited, but the research that does exist suggests limited generalizability to the unique biopsychosocial context of later life. To further examine the applicability of the AMPD to older adults, the purpose of this study was to examine relationships between the AMPD's two constructs with perceived physical health status among younger and older adult samples. Older adults (n = 222) and younger adults (n = 215) completed the Short Form-36 (SF-36), Levels of Personality Functioning Scale-Self-Report (LPFS-SR), and Personality Inventory for DSM-5-Brief Form (PID-5-BF). Correlations and Fisher's z-tests revealed significantly stronger relationships between the SF-36 with the LPFS-SR and PID-5-BF domains for older adults than younger adults. Additionally, age group significantly moderated the relationships between personality functioning and pathological personality traits and health. The stronger relationships between health and the AMPD's constructs for older adults suggest meaningful overlap between negative health outcomes and PD pathology. Future research should further investigate specific mechanisms in which personality pathology negatively impacts health in older adults.

Incidence of Orthodontic Bracket Detachment and Associated Factors among Individuals Undergoing Orthodontic Treatment

Objective: The objective of this study is to evaluate the incidence of orthodontic bracket detachment (OBD) and associated factors among individuals undergoing orthodontic treatment. Materials and Methods: We conducted a cross-sectional study among the individuals undergoing orthodontic treatment at our center. We included participants aged 18 and above who underwent orthodontic treatment for at least 6 months or more and those willing to participate. We excluded participants whose orthodontic treatment started elsewhere and participants with syndromes. A specially designed self-administered questionnaire in English was developed, which included information on age, sex, education, duration of orthodontic treatment, number of orthodontic brackets detached, frequency, and reasons. Personality Inventory for DSM-5 Brief Form (PID-5-BF) for adults was used to evaluate the personality traits of the participant. Results: One hundred and thirty-four individuals completed this study, of which 43.3% were males (mean age: 21.29 ± 3.23). The incidence of OBD was 32.1%. The mean duration of the treatment was significantly higher among those with OBD than those without OBD (P = 0.007). However, there were no significant differences in the mean domain scores and total scores of PID-5-BF between the individuals with or without OBD. It was seen that the duration of orthodontic treatment was significantly associated with OBD (odds ratio = 1.07; 95% confidence interval = 1.02–1.12). Conclusion: Our study showed that the treatment duration was higher among individuals with OBD.

Validation of the Personality Inventory for DSM-5–Brief Form (PID-5-BF) with Iranian University Students and Clinical Samples: Factor Structure, Measurement Invariance, and Convergent, Discriminant, and Known-Groups Validity

The Personality Inventory for DSM–5, Brief Form (PID-5-BF) was developed to assess DSM-5's Alternative Trait Model for Diagnosing Personality Disorders (AMPD). This study aimed to examine the factor structure, internal consistency, measurement invariance, and convergent, discriminant, and known-group validity of the Persian PID-5-BF with 941 university students (aged 18–67, M age= 28.36, SD = 9.09, 39.1% males) and 178 male from a clinical (aged 18–60, M age= 33.77, SD = 10.60) sample in Iran. Confirmatory factor analyses supported the five-factor model in both groups, being fully and partially invariant across gender and study groups, respectively. PID-5-BF subscales were internally consistent, yielded expected associations with other personality variables, and differentiated the student sample from the clinical group, supporting the measure’s convergent, discriminant, and known-group validity. Our results indicated that the PID-5-BF holds promise as a screening measure of dimensional maladaptive personality traits in Iranian students and clinical samples.

Reliability and factorial validity of long and brief versions of the inventory of personality organization in a Latvian sample.

The aim of this study was to examine the construct validity and reliability of long and brief versions (57 and 16 items) of the inventory of personality organization (IPO) in a Latvian nonclinical sample. The actuality of this study is dictated by the number of persons suffering from personality disorders, and the excessive need for reliable constructs for the assessment of personality in the normality-abnormality range. The total number of participants of the study was 1118, recruited in several subsamples, which were employed for the investigation of the factor structure, psychometric properties, test-retest, and convergent validity of the IPO-57 and IPO-16 scales. The 3-factor structure, obtained by confirmatory factor analysis, was replicated in the Latvian-speaking sample for long and brief IPO versions. Both constructs achieved adequate model fit psychometric indices and sufficient internal consistency, and the test-retest reliability was also approved. The convergent validity of IPO with aggressivity, negative affectivity, and non-adaptive personality measures was established. In the current study, we adapted a very fundamental psychodynamic/psychoanalytic construct in the Latvian language and replicated the previously empirically established IPO three-dimensional model, whereas the novelty in IPO construct convergent validity research was the establishment of convergent validity with non-adaptive personality traits measured by the Personality Inventory for DSM-5 Brief Form (PID-5-BF). Both versions of IPO are recommended for further use in the research in Latvian language samples, for clinical purposes to assess the level of psychic functioning, and for treatment planning and evaluation purposes.

Evaluation of the factor structure of the Russian version of PID-5-BF

IntroductionTraditional categorical classifications of personality disorders (PD) have been criticized for insufficient structural and cross-cultural validity. In the DSM-5 Section III, alternative model of the PDs (AMPD), the maladaptive personality traits are divided into five domains: negative affect, detachment, antagonism, disinhibition and psychoticism. The Personality Inventory for DSM-5 Brief Form (PID-5-BF) is a 25-item self-report questionnaire that measures the severity of each of these five domains. To date, no questionnaires assessing pathological personality traits following the AMPD have been validated in Russia.ObjectivesThis study aimed to investigate the factor structure of the Russian version of PID-5-BF.MethodsFive hundred and 86 (female - 505 (86,2%), age - 18–77 years (M - 28.2, SD - 11.5)) consecutive inpatients with non-psychotic mental disorders were assessed with the Russian language version of the PID-5-BF. Exploratory structural equation modelling (ESEM) with Robust Diagonally Weighted Least Squares method of extraction and Robust Equamax rotation was performed in Factor v 11.04.02.ResultsThe results of the ESEM analysis showed good fit of the five-factor model (CFI - 0.982; TLI - 0.971; RMSEA (95% CI) - 0.036 (0.01-0.05). Most of the items had the highest factor loadings on their mother domains. However, two items showed weak loadings on their designated factors (<0.4), and attention seeking item had a primary load to (low) detachment instead of antagonism.ConclusionsThe PID-5-BF was found to be a valid and reliable tool for the evaluation of the AMPD trait domainDisclosureNo significant relationships.

Functional Impairment in Borderline Personality Disorder: The Mediating Role of Perceived Social Support.

Borderline personality disorder (BPD) is characterized by instability in relationships, mood fluctuations, and erratic behavior. This study investigates the relationship between pathological personality traits and functional disability, the status of perceived social support in BPD, as well as its mediating role in this relationship. In this cross-sectional study, 192 Spanish women (BPD group, N = 97; healthy control group, N = 95) completed, through two online platforms, a battery of tests including: the Personality Inventory for DSM-5 Brief Form (PID-5-BF), the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) and the Perceived Social Support subscale of the Quality of Life Questionnaire (QLQ). The results show that perceived social support was significantly lower in the BPD group, which also presented a significantly higher disability score than the control group. Pathological personality traits affected functionality both directly and indirectly through perceived social support, as this variable was a significant mediator in both groups. We conclude that perceived social support is impaired in BPD patients, and enhancing it as a complementary therapy to evidence-based treatments could help preserve the functionality of patients while pathological traits are regulated. This study also encourages future research to delve into the relevance of other psychosocial variables on the functionality of subjects with BPD, and the need of enhancing them in therapy.

Supplemental Material for Personality Inventory for DSM–5-Brief Form (PID-5-BF): Measurement Invariance Across Men and Women

Supplemental Material for Personality Inventory for DSM–5-Brief Form (PID-5-BF): Measurement Invariance Across Men and Women

Gaming and gambling in adolescence: the role of personality, reflective functioning, time perspective and dissociation

ABSTRACT The 11th Revision of the International Classification of Diseases (ICD-11) formally recognized gaming disorder as an addictive health disorder like gambling disorder. The ICD-11 assumes that excessive online gaming can lead to functional/clinical impairments and psychological distress among a minority of individuals. The present study investigated similarities and commonalities between internet gaming disorder (IGD) and gambling disorder among adolescents (N = 366 students, 13–19 years). Participants completed the South Oaks Gambling Screen Revised for Adolescents (SOGS-RA), the Internet Gaming Disorder Scale-Short Form (IGDS9-SF), the Personality Inventory for DSM-5 Brief Form (PID-5-BF), the Reflective Functioning Questionnaire (RFQ-8), the Consideration of Future Consequences Scale (CFC-14), and the Adolescent Dissociative Experiences Scale (A-DES). Regression analyses showed that the significant predictors of (i) gambling severity were being male, high scores on the PID-5-BF Disinhibition and Antagonism domains, and low scores on RFQ-Certainty and CFC-Future subscales, and (ii) gaming severity were being male, high scores on the PID-5-BF Detachment scale and the A-DES, and low scores on the RFQ-Certainty. Risk factors shared by both disorders were male gender and impaired mentalization. Specific interventions on mentalization abilities may be useful in reducing and preventing problematic involvement in both gaming and gambling among adolescents.

Screening for borderline personality pathology on college campuses.

Although borderline symptoms show a normative decline throughout adulthood, severe psychosocial impairment often remains. Identifying personality pathology in college-age students may help prevent "adaptive failure" that can occur during the critical period of development from puberty through the late 20s and thus reduce impairment later in life. The aims of the current study were to estimate the prevalence of borderline personality disorder (BPD) in a diverse college sample, determine which symptoms confer the greatest relative risk of screening positive for BPD and examine the utility of the Personality Inventory for DSM-5 brief form (PID-5-BF) in identifying BPD. Participants were 1456 undergraduate students, and 312 individuals (21.4% of the sample) screened positive for BPD. Chronic feelings of emptiness conferred the greatest relative risk of any symptom; students who endorsed this symptom were 15 times more likely to screen positive for BPD than those who did not. Scales and composite scores of the PID-5-BF demonstrated diagnostic accuracy ranging from sufficient to excellent. The current study contributes to literature concerning best practices in screening for personality pathology in young adults. Results suggest that chronic feelings of emptiness are significant for detecting at-risk students and implications for the use of the PID-5-BF are discussed.

Understanding the relationship between personality pathology and attachment style in the context of the DSM‐5 Alternative Model of Personality Disorders

This study utilizes the two different criteria of the DSM-5 Alternative Model of Personality Disorder Assessment to evaluate the relationship between attachment style and personality pathology. One-hundred forty patients from a combined sample of psychiatric and internal medicine clinics were given a survey composed of the DSM-5 Levels of Personality Functioning Questionnaire (DLOPFQ), the Personality Inventory for DSM-5-Brief Form (PID-5-BF), and the Relationship Questionnaire (RQ). Analysis of variance indicated that attachment styles were differentiated across all four the DLOPFQ scales and the Detachment trait domain. Elastic net regression modeling with bootstrap was used to assess the strength of the level of personality functioning dimensions and trait domains in the prediction of attachment style, both independently and interactively while accounting for multicollinearity. This study offers readers insight to a novel statistical approach to model building that addresses two issues among psychiatric data: high correlation and small sample size.

Borderline Personality Traits: The Roles of Childhood Teasing and Traumatic Experiences

Background and Objective: The relationship of borderline personality traits with childhood teasing and traumatic experiences is a major risk factor in the development of borderline personality disorder (BPD) symptoms; nonetheless, this relationship is not fully understood. The present study aimed to provide further evidence on the role of childhood teasing, traumatic experiences, and other pathological personality traits, such as negative affectivity, antagonism, psychoticism, disinhibition, detachment, depression, anxiety, and stress symptom, in the development of borderline personality disorder, especially in Iranian non-clinical populations. Materials and Methods: A total of 385 college students were assessed by teasing questionnaire-revised (TQ-R), childhood trauma questionnaire (CTQ), Personality Inventory for DSM-5 Brief Form (PID-5-BF), the borderline personality scale (SIB), and the depression, anxiety, and stress scale (DASS-21). Results: Descriptive statistics, Pearson Correlations, and stepwise regression analysis statistics were conducted to examine the relationship of borderline personality traits with childhood teasing and traumatic experiences. The current study supported the significant positive correlation of borderline personality disorder with PID-5-BF, such as negative affectivity, antagonism, psychoticism, disinhibition, detachment, depression, anxiety, and stress symptoms, as well as teasing and traumatic experiences in non-clinical individuals. Conclusions: As evidenced by the results of this study, childhood traumatic experiences have a prominent role to play in the development of borderline personality psychopathology.

Personality inventory for DSM-5 brief form(PID-5-BF) in Chinese students and patients: evaluating the five-factor model and a culturally informed six-factor model

BackgroundThe Personality Inventory for DSM-5 Brief Form (PID-5-BF) is a 25-item measuring tool evaluating maladaptive personality traits for the diagnosis of personality disorders(PDs). As a promising scale, its impressive psychometric properties have been verified in some countries, however, there have been no studies about the utility of the PID-5-BF in Chinese settings. The current study aimed to explore the maladaptive personality factor model which was culturally adapted to China and to examine psychometric properties of the PID-5-BF among Chinese undergraduate students and clinical patients.MethodsSeven thousand one hundred fifty-five undergraduate students and 451 clinical patients completed the Chinese version of the PID-5-BF. Two hundered twenty-eight students were chosen randomly for test-retest reliability at a 4-week interval. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted to discover the most suitable factor structure in China, measurement invariance(MI), internal consistency, and external validity were also calculated.ResultsThe theoretical five-factor model was acceptable, but the exploratory six-factor model was more applicable in both samples (Undergraduate sample: CFI = 0.905, TLI = 0.888, RMSEA = 0.044, SRMR = 0.039; Clinical sample: CFI = 0.904, TLI = 0.886, RMSEA = 0.047, SRMR = 0.060). In the Chinese six-factor model, the Negative Affect domain was divided into two factors and the new factor was named “Interpersonal Relationships”, which was in line with the Big-Six Personality model in Chinese. Measurement invariance across non-clinical and clinical sample was established (configural, weak, strong MI, and partial strict MI). Aside from acceptable internal consistency (Undergraduate sample: alpha = 0.84, MIC = 0.21; Clinical sample: alpha = 0.86, MIC = 0.19) and test-retest reliability(0.73), the correlation between the 25-item PID-5-BF and the 220-item PID-5 was significant(p < 0.01). The six PDs measured by Personality diagnostic questionnaire-4+ (PDQ-4+) were associated with and predicted by expected domains of PID-5-BF.ConclusionsBoth the theoretical five-factor model and the exploratory six-factor model of the PID-5-BF were acceptable to the Chinese population. The five-factor model could allow for comparison and integration with other work on the original theoretical model. However, the Chinese six-factor structure may be more culturally informed in East Asian settings. In sum, the PID-5-BF is a convenient and useful screening tool for personality disorders.

The Personality Inventory for DSM-5-Brief Form: An Examination of Internal Consistency, Factor Structure, and Relationship to Aggression in an Incarcerated Offender Sample.

This study evaluated the internal consistency and factor structure of the Personality Inventory for DSM-5-Brief Form (PID-5-BF), and its relationship to aggression in 438 incarcerated Australian male offenders. Results provide support for the internal consistency and five-factor and bifactor structure of the PID-5-BF. The PID-5-BF total score, as well as the domains of Antagonism, Disinhibition, and Negative Affect (low), demonstrated significant relationships with aggression. These results provide preliminary support for the psychometric properties of the PID-5-BF within prison settings, and suggest that a PID-5-BF assessment may be useful within forensic settings to screen for broad maladaptive personality characteristics that are indicative of a greater propensity for aggressive behavior.

Reduction of Gender Identity Stigma and Improvements in Mental Health Among Transgender Women Initiating HIV Treatment in a Trans-Sensitive Clinic in Argentina.

Purpose: Stigma toward transgender women (TGW) increases psychosocial vulnerability, leading to poor mental health and affecting access and retention in HIV care. Trans-sensitive health care (TSHC) has the potential to mitigate this adverse impact. This study aimed to describe baseline characteristics in gender identity stigma (GIS), mental health, and substance use among TGW living with HIV initiating antiretroviral treatment and to analyze changes after 6 months in HIV care in a TSHC clinic in Argentina. Methods: Sixty-one TGW living with HIV responded to the following questionnaires at baseline and after 6 months in TSHC: sociodemographic, experiences of GIS (in health care, police, etc.), Center for Epidemiologic Studies Depression Scale (CES-D) (depression), State Trait Anxiety Inventory (STAI) (anxiety), Drug Abuse Screening Test (DAST-10) (drug use), Alcohol Use Disorders Identification Test (AUDIT) (alcohol use), 8-item Personal Wellbeing Index-Adults (PWI-A) (quality of life [QOL]), Personality Inventory for DSM-5-Brief Form (PID-5-BF) (maladaptive personality traits), and Duke Index (social support). Analyses included Pearson correlations to analyze associations between variables; and paired sample t-tests, to explore changes between baseline and 6 months. Results: A significant proportion experienced episodes of GIS the last year in any context. At baseline, 50.8% showed significant depressive symptoms and 65.6% reported any drug use in the last year. At 6 months, participants experienced a significant reduction of GIS, both enacted and internalized, anxiety, drug, and alcohol use, and improvement in QOL. The remaining mental health indicators were not significantly modified. Conclusion: A TSHC service may have a gender-affirmative impact on TGW initiating HIV care that contributes to reduce GIS and substance use and improve mental health. This highlights the importance that HIV care programs for TGW comply with trans-sensitive essential components to enhance retention.