ABSTRACTExperimental evidence indicates that multidimensional cyclic loading of soils causes larger accumulation of deformations than equivalent one‐dimensional loading. The response of sand to high‐cyclic loading with 10,000 cycles and up to four‐dimensional stress paths (i.e., four independent oscillating components) is examined in 120 triaxial and hollow cylinder tests in this work to extend these findings. With increasing number of oscillating stress components, the accumulation of permanent strains tends to increase. It is demonstrated that the definition of the multidimensional strain amplitude incorporated in the high‐cycle accumulation (HCA) model can account for this. The validation of the HCA model for complex cyclic loading is complemented by the simulation of model tests on monopile foundations of offshore wind turbines subjected to multidirectional cyclic loading, for which the consideration of spatially variable cyclic loading with nonconstant load amplitudes in the HCA model is discussed. For this purpose, an extension of the HCA model considering multiple strain amplitudes is presented.