Permanent First Molars Research Articles

To Treat or to Extract Necrotic First Permanent Molars Between 8 and 12 Years of Age: A Retrospective Cohort Study.

Background: First permanent molars (FPM) are highly susceptible to decay before the age of 15. When they are severely affected, the decision between conservation and extraction arises, particularly considering the potential for the second permanent molar (SPM) to replace the FPM. This cohort study aimed to evaluate clinical practices regarding FPM pulp necrosis treatment in children aged eight to twelve in two hospital departments in the Paris region. A second objective was to evaluate the one-year outcomes of the two therapies. Methods: A retrospective analysis was conducted using computerized billing software to identify patients aged eight to twelve who underwent either extraction or root canal treatment (RCT). Data collected included sex, age, arch involved, number of decayed surfaces, presence of Molar Incisor Hypomineralization (MIH), presence of infection, and treatment type. Results: A total of 66 patients were included, representing 61 extracted teeth and 23 RCT. Three main decision criteria were identified: presence of MIH (p < 0.005), extent of decay (p < 0.05), and SPM Nolla's stage. A total of 48% of the patients were seen at one year. A total of 16 of the 32 extractions and five of the nine RCTs had favorable evolution (p = 1). Conclusions: The question of whether to perform RCT or extraction of necrotic FPM in children aged eight to twelve is difficult to assess. It appears that five criteria need to be considered before the decision: possibility of long-term sealed coronal reconstruction, SPM Nolla's stage, follow-up possibilities, arch concerned, and presence of third permanent molar.

Spontaneous space closure after extraction of young first permanent molar. Retrospective cohort study.

Early compromised first-permanent-molar (FPM) extraction can adversely affect occlusion. However, the current literature does not provide sufficient support for definitive early extraction outcome. This cohort study aimed to evaluate the pattern of post-FPM extraction spontaneous space closure and its pre-extraction indicators. Patients of 7-13 years, with compromised FPM at three-tertiary-centers between 2015 and 2019 were retrospectively screened. Pre-extraction indicators were evaluated (extraction location, direction of the second permanent molar (SPM) long-axis, and SPM Demirjian development stage). Spontaneous space closure pattern was evaluated clinically and radiographically using the American Board of Orthodontics (ABO) grading system. In total, 112 FPMs (73-patients) were identified and five (4.5%) of the extraction sites showed favorable combined-ABO-scores. Distal direction of the SPM long-axis in the maxillary arch significantly decreased the relative risk (RR) of having a SPM rotation/alignment ABO score-1 (P = 0.002; RR = 0.64). For the mandibular arch, Demirjian stage D and E significantly decreased the RR of having ABO score-1 for spacing between the SPMs and second premolars (P = 0.029; RR:0.57, P = 0.004; RR:0.53, respectively) and vertical dimension (P = 0.02; RR = 0.53). The direction of the SPM long-axis and its developmental stage are key indicators of the favorable outcome pattern of spontaneous space closure after FPM early extraction.

Eruption and caries status of first permanent molars in children aged 6–7 years in Shijingshan District, Beijing, China

BackgroundDental caries is still a major disease that affect the oral health of people in China. First permanent molars (FPMs) are the most caries-susceptible teeth among school-aged children. The aim of this study was to investigate the eruption and caries status of first permanent molars in children aged 6–7 years in Shijingshan District, Beijing, China, to provide information for oral health promotion.Methods The study was a cross-sectional survey conducted in 6-7-year-old first grade children from public elementary schools in Shijingshan District, Beijing. Participants were invited to receive a clinical oral examination. The eruption status and caries experience of FPMs were recorded. Questionnaires assessing children’s sociodemographic information and oral health-related behaviors were completed by the children’s parents or guardians.ResultsA total of 3,176 children, including 1,644 boys (51.8%) and 1,532 girls (48.2%) were included in the oral examination and questionnaire. Eruption status of FPMs was as follows: 37.5% fully erupted, 28.3% partially erupted, 34.2% not erupted. Girls had more erupted FPMs than boys (70.1% VS 61.8%, P < 0.001). The prevalence of dental caries in FPMs was 5.5% (174/3,176) in studied children. The mean decayed missing filled teeth score of FPMs was 0.11 and the mean decayed missing filled surface score of FPMs was 0.19. Binary Logistic regression analysis demonstrated that girls had more tooth decay than boys and father’s educational background also associated with the caries experience of the studied children (P < 0.05).ConclusionsAround two-thirds of FPMs were fully erupted or partially erupted among children aged 6–7 years old in Shijingshan District, Beijing. Approximately 5% of the newly erupted FPM established dental caries. Effective intervention should be applied in this age group for oral health promotion.

Perceptions, attitudes, and clinical experiences of Brazilian dental practitioners towards molar incisor hypomineralisation: a cross-sectional study.

To evaluate perceptions, attitudes, and clinical experience of Brazilian dental practitioners regarding molar incisor hypomineralisation (MIH). An online survey with 27 questions, covering professional profile data, perceptions, and knowledge on clinical management of MIH, was employed. Descriptive analyses, chi-square, Fisher's exact, and Cramer's V tests were used. Sample comprised 100 participants, equally distributed between those working in private or public sectors. Most private sector practitioners had 21-30years of clinical experience (28%) and master's degree (50%), while most public sector practitioners had 11-20years of clinical experience (32%) and a PhD degree (32%). Most participants (86%) recognized MIH in their practice. Statistically significant differences were observed in frequency (p = 0.001), incidence (p = 0.039), and lesion type (p = 0.043) between practitioners from both sectors. Uncertainly in management was reported by 49%, mainly in public sector. For mild MIH in incisors, no treatment was chosen (43%), and the treatment longevity was the only significant factor reported (p = 0.012). In cases of mild MIH in first permanent molars (FPMs), 51% of respondents opted to keep the affected tissue and apply fissure sealant. Glass ionomer (GI) restoration was commonly indicated for FPMs with severe MIH with moderate loss of structure and sensitivity (38%). In cases with substantial structural loss and pulpal involvement, the most chosen treatment was endodontic intervention combined with preformed crowns. Brazilian dental practitioners face MIH in clinical practice. Although, public sector professionals are less confident in diagnosis and treatment, no significant differences in treatment preferences between public and private sector dental practitioners were identified.

Computerised assessment-a novel approach for calculation of percentage of hypomineralized lesion on incisors and its correlation with aesthetic concern

IntroductionMolar-incisor hypomineralization (MIH) is a localized, qualitative, demarcated enamel defect that affects first permanent molars (FPMs) and/or permanent incisors. The aim of present study was to introduce a novel computerised assessment process to detect and quantify the percentage opacity associated with MIH affected maxillary central incisors. MethodologyChildren (8–16 years) enrolled in the primary study having mild (white/cream or yellow/brown) MIH lesion on fully erupted maxillary permanent central incisor. 50 standardised images of MIH lesions were captured in an artificially lit room with fixed parameters and were anonymized and securely stored. Images were analysed by AI-driven computerised software and generates output classifications via a sophisticated algorithm crafted using a meticulously annotated image dataset as reference through supervised machine learning (SML). For the validation of computerised assessment of MIH lesions, the percentage of demarked opacity was calculated using ADOBE PHOTOSHOP CS7. ResultsThe percentage of MIH lesion was calculated through histogram plotting with the maxima ranging from 7.29 % to 71.21 % with the mean value of 34.51 %. The validation score ranged from 10.29 % to 67.27 % with the mean value of 35.32 %. The difference between the two was statistically not significant. Out of 50 patients; 11 patients had 1–30 % of surface affected with MIH and 2 had aesthetic concern; 24 had 30–60 % of surface affected and 13 had aesthetic concern; 15 had >60 % of surface affected and 12 had aesthetic concerns. ConclusionsThe proposed approach exhibit sufficient quality to be integrated into a dental software addressing practical challenges encountered in daily clinical settings.

SPATIAL DISTRIBUTION OF MOLAR INCISOR HYPOMINERALIZATION (MIH) OPACITIES IN FIRST PERMANENT MOLARS

Aim: To evaluate the spatial distribution of MIH opacities in first permanent molars (FPM). Materials and methods: an analysis of intraoral photographs of FPM with demarcated MIH opacities was conducted. The presence of opacity was computed in a digital matrix, discriminating the anatomical regions of the FPM surfaces. The frequencies of distribution of the opacities were descriptively analyzed through 227 FPM digital images of 89 children built in GIMP and Python and by Spearman correlation (= 0,05). Results: the occlusal surface was the most affected one (94% to 100%). In the upper FPM, the palatine surface was the second most affected one (84%-91%). In the lower FPM, the vestibular surface was the second most affected one (85%-80%). A similar pattern of opacity distribution was observed in the contralateral teeth. On smooth surfaces, opacities were more frequent in the regions closer to the occlusal surface than to the cervical one. Conclusion: MIH opacities were mostly present on occlusal, vestibular, and lingual/palatine surfaces, respectively. There is a possibility that the occurrences are in accordance with the chronology of dental formation. Keywords: Molar Incisor Hypomineralization, First Permanent Molars, Dental photography, intraoral photography

Cost-effectiveness and cost–benefit analyses of fluoride varnish for caries prevention in Guangxi, China

ObjectivesThe objectives of this study were to evaluate the cost-effectiveness and cost-benefit of fluoride varnish (FV) interventions for preventing caries in the first permanent molars (FPMs) among children in rural areas in Guangxi, China.MethodsThis study constituted a secondary analysis of data from a randomised controlled trial, analysed from a social perspective. A total of 1,335 children aged 6–8 years in remote rural areas of Guangxi were enrolled in this three-year follow-up controlled study. Children in the experimental group (EG) and the control group (CG) received oral health education and were provided with a toothbrush and toothpaste once every six months. Additionally, FV was applied in the EG. A decision tree model was developed, and single-factor and probabilistic sensitivity analyses were conducted.ResultsAfter three years of intervention, the prevalence of caries in the EG was 50.85%, with an average decayed, missing, and filled teeth (DMFT) index score of 1.12, and that in the CG was 59.04%, with a DMFT index score of 1.36. The total cost of caries intervention and postcaries treatment was 42,719.55 USD for the EG and 46,622.13 USD for the CG. The incremental cost-effectiveness ratio (ICER) of the EG was 25.36 USD per caries prevented, and the cost–benefit ratio (CBR) was 1.74 USD benefits per 1 USD cost. The results of the sensitivity analyses showed that the increase in the average DMFT index score was the largest variable affecting the ICER and CBR.ConclusionsCompared to oral health education alone, a comprehensive intervention combining FV application with oral health education is more cost-effective and beneficial for preventing caries in the FPMs of children living in economically disadvantaged rural areas. These findings could provide a basis for policy-making and clinical choices to improve children’s oral health.

Fissure Sealants or Fluoride Varnish? A Randomized Pragmatic Split-Mouth Trial

This study aimed to compare the clinical effectiveness of resin-based fissure sealants (FS) and fluoride varnish (FV) in children at high caries risk. A practice-based split-mouth randomized clinical trial was conducted at 9 Public Dental Service (PDS) clinics in Norway. In total, 409 children age 6 to 10 y at high caries risk (d3mft > 0) meeting inclusion criteria were recruited by dentists and dental hygienists during routine examination. Eligibility criteria were 2 fully erupted first permanent molars (FPMs) in the same jaw, with sound occlusal surfaces or with initial caries. Participation was voluntary, caregivers and eligible children were informed about the study, and written parental consent was obtained. FS and FV were randomly applied on contralateral FPMs in the same jaw, with each participant serving as their own control. FS was applied at baseline and thereafter maintained according to clinicians’ conventional procedures, whereas FV was applied at baseline, 6 mo, and 12 mo. The study outcome was success, with no need for invasive treatment (caries control), while failure was defined as dentin carious lesion or restoration. Two-level mixed-effects logistic regression analysis was used to compare FS and FV groups. Of 409 recruited children, 369 (90%) children/tooth pairs were examined after 36 mo. Intention-to-treat analysis showed 94.1% adjusted predicted probability (aPP) of success (95% confidence interval [CI] 91.7 to 96.4) in the FS group and 89.6% aPP (95% CI 86.5 to 92.7) in the FV group. In the adjusted analysis, the FV group had a lower OR for success compared with the FS group (OR 0.54, 95% CI 0.24 to 0.87). In the population studied, the clinical effectiveness of FS was statistically significantly higher compared with FV but below the estimated minimal clinically important difference of 10%.

Oral Health-Related Quality of Life Following Root Canal Treatment of First Permanent Molars Among Children. A Cross-Sectional Study.

This study aimed to assess the Oral Health-Related Quality of Life (OHRQoL) of pediatric patients (9-18 years old) who underwent root canal treatment (RCT) on first permanent molars (FPMs). A cross-sectional study was conducted at three healthcare centers in Jeddah, Saudi Arabia. Participants (n = 482) completed the validated OHIP5-Ar questionnaire to assess OHRQoL. Responses were classified as "optimal" (no problems) or "less than optimal" (any reported problems). Logistic regression analyzed the relationship between OHRQoL and sociodemographic factors. There were 66.8% children reported optimal OHRQoL after RCT. Logistic regression showed no significant association between optimal OHRQoL and gender, family income, or location of treated tooth. However, although not statistically significant. Treating only one FPM with RCT (compared to multiple teeth) and lower family income (compared to higher income) were more likely to have decreased or increased odds of optimal OHRQoL (AOR = 0.684 or 1.424; respectively). RCT on FPMs can be a successful treatment option for pediatric patients, offering optimal oral health-related quality of life.

Clinical efficacy of the Invisalign mandibular advancement appliance: A retrospective investigation

This retrospective investigation aimed to determine whether the achieved changes in the treatment of Class II malocclusion were the same as those planned after the prescribed wear of an initial phase of Invisalign treatment with the mandibular advancement appliance (MAA) (Align Technology, Santa Jose, Calif). All patients treated with the MAA and who satisfied inclusion/exclusion criteria were selected from a database of 16,500 patients treated with clear aligners by 16 orthodontists. The pretreatment, planned, and achieved overjet measurements were documented from data provided in Align Technology's software facility, ClinCheck. Changes in intermaxillary anteroposterior (AP) first permanent molar (FPM) relationships were evaluated using Geomagic Control X (3D systems, Rock Hill, SC) metrology software. Most of the 195 patients who satisfied the inclusion criteria were females (n= 104; 53.3%). The mean age was 12.62 ± 2.20 years. The pretreatment overjet was reduced from 6.49 ± 2.86 mm to 4.61 ± 2.22 mm after prescribed MAA wear, which was 42.5% of the planned outcome. The pretreatment AP FPM reduced from 3.14 ± 1.95 mm to 2.24 ± 2.51 mm, which was 31.3% of that planned. Thirty-eight (19.5%) patients experienced an increase in overjet where a reduction was planned. Less than half of the planned overjet reduction and less than a third of the planned AP FPM correction were achieved with the MAA. Almost 20% of patients completed the MAA phase of treatment with an increased overjet despite a reduction being planned.

Assessment of caries diagnostic threshold of DMFT, and ICDAS II in the estimation of caries prevalence rate in first permanent molars among students of College of Dentistry-Hawler Medical University.

Background: Dental caries is a common chronic infectious disease resulting from tooth-adherent cariogenic bacteria primarily S. Mutans, which metabolize sugars to produce acid, demineralizing the tooth structure over time. First permanent molars (FPMs) have a key role in establishing dental occlusion. They are very prone to caries because of their anatomical structure and early eruption. Hence, the estimation of dental caries in FPMs at individual and community levels could help understand the pattern and severity of dental caries. Aim: The current study aimed to evaluate the caries prevalence of FPMs amongst the students of collage of dentistry/HMU. The rate of decay between male and female, maxillary and mandibular FPM teeth. Method: This study was carried out among the students of Hawler medical university/college of dentistry. The total number of samples was (100) samples. The age of the students ranged from (18-24 years) of age. Clinical examinations were carried out under artificial light using dental mirrors and dental probe/explorers. Dental caries was diagnosed on teeth number (3, 14, 19, and 30), according to the criteria of DMFT index looking for missing, filling, decayed teeth. then ICDAS to further classify the amount of dental caries later the collected data was analyzed by using SPSS. Results: in this study the difference in decay between maxillary and mandibular teeth was significant with the P value being (0.27). Between genders the P value was (0.38) and between age groups was (0.30) their result being insignificant, according to chi-square test. Conclusion: this study indicates that; the rate of decay is more in mandibular FPMs in comparison to maxillary FPMs. While the difference between the male, female and different age group in caries prevalence are non-significant, hence, more education about the aforementioned problems is necessary. Keywords: Caries Diagnostic Threshold, Prevalence Rate.

Hall Technique for the management of hypomineralized first permanent molars: A protocol of a randomized controlled trial with 3-year follow-up

The aim of this clinical protocol is to describe the methodology for the evaluation of the clinical performance of Hall Technique (HT) in comparison with glass ionomer cement (GIC) restorations in first permanent molars (FPM) severely affected by molar incisor hypomineralization (MIH). This protocol is related to a two-arm, parallel group, controlled and randomized superiority trial. It will be included 92 participants, 6 to 12 years-old, presenting at least one FPM with post-eruptive enamel breakdown and/or atypical caries and/or unsatisfactory atypical restoration involving cusp and extending to at least two tooth surfaces. Two trained and calibrated dentists will select the participants and assess the outcomes. Eight experienced clinicians who work as dentists at the public oral health system will be trained to perform the interventions. The participants will be randomized into the test (HT) or the control group (GIC). The outcomes will be assessed every 6 months up to 3 years. The primary outcome is the survival rate of the restorations. Secondary outcomes include satisfaction of the participants, parents, and dentists; impact on oral heath related quality of life; self-reported discomfort during treatment; signs/symptoms of temporomandibular joint dysfunction; and cost-effectiveness. Kaplan-Meier and Cox regression analysis will be used to analyze the primary outcome. Mann-Whitney or t-test will be used to compare the secondary outcomes between groups. We expect to provide scientific evidence about the treatment approach that maximizes success rates and minimizes retreatments in severe HMI.

The Prevalence, Severity and Pattern of First Permanent Molars’ Dental Caries in Children Attending A Postgraduate Dental Hospital: A Retrospective Study

Introduction: First permanent molars (FPMs) erupt early and their anatomy and location leave them susceptible to dental caries. This study aimed to retrospectively determine the prevalence, severity and pattern of dental caries of FPMs and investigate their relationship if any with demographics and medical health status of the partcipants. Methods: This was a retrospective cross-sectional study. A sample of the digital case notes and radiographs of children aged 5 to 12 years who attended the only postgraduate dental hospital in Dubai were accessed. The recorded data included the children’s demographic variables and the carious status of each FPM as recorded in the notes on the initial assessment. Descriptive and statistical analyses were conducted (P&lt;0.05). Results: A total of 2984 FPMs were obtained from the digital records of 774 children. Their mean age was 8.07 (±2.23) years and only those that met the inclusion criteria were included in the study. The prevalence of dental caries and mean Decayed Missing Filled Surfaces of FPMs, were 42% and 0.3 (±0.04), respectively. The most prevalent decayed surface was the occlusal (29.2%), followed by mesial, buccal, palatal/ lingual, distal surfaces (24.2 %; 6.6 %; 3.1 %; 2.3 %) respectively. Children with medical problems and/or special needs had a significantly higher level of caries in the buccal surfaces (12.3%) (P=0.042). Conclusion: Caries of FPMs in a sample of Dubai children studied was prevalent, especially in those with special healthcare needs, thus indicating a necessity for targeted prevention and treatment focused on these keystone teeth.

Clinical Characteristics and Differential Diagnosis of Hypomineralised Second Primary Molars and Molar Incisor Hypomineralisation.

Molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPMs) are commonly seen dental developmental problems with a mean prevalence of around 14% and 9%, respectively, but with a large variability in the reported prevalences. From the dental development, we know that the enamel mineralisation of the second primary molar is taking place between the 19th week of pregnancy until 1 year of age. For the first permanent molars (FPMs) and incisors, the enamel mineralisation is taking place between birth until the age of 3-5. When there is a disturbance during this period, HSPM and/or MIH can occur. There is an overlap in the development of the second primary molars and the FPMs and incisors; the period between birth and the first birthday of the child. A disturbance in this period could cause both HSPM and MIH. There is a relation found in the occurrence of HSPM and MIH. Diagnosing HSPM and MIH can be challenging. All teeth present in the mouth need to be examined. The use of the European Association of Paediatric Dentistry scoring criteria is a good help. In these criteria also, the most common differential diagnoses are included.

Spontaneous space closure in patients treated with early extraction of the first permanent molar: a retrospective cohort study using radiographs.

To assess the success rate of spontaneous space closure after extraction of the first permanent molar (FPM) in the maxilla and the mandible, and to identify the factors that make spontaneous space closure most favorable in each. A retrospective records-based cohort study was conducted through a search of the database of the Public Dental Service, Stockholm County Council, Stockholm, for young adults born between 2000 and 2001, who underwent extraction of one or more FPM between 2006 and 2016. A total of 995 extracted teeth were identified, of which 203 teeth in 155 patients met the inclusion criteria. Of the 203 extracted teeth, 166 (81.8%) did not receive any orthodontic treatment. The success rate for space closure in orthodontically treated patients was 91.9%. The success rate for spontaneous space closure was 84.3%. All unsuccessful spontaneous space closure in the maxilla occurred in patients older than 12 years. The dental developmental stage of the second permanent molar (SPM) had a statistically significant association with spontaneous space closure in the mandible (P < .001). The success rate of spontaneous space closure was high (84.3%) and was higher in the maxilla (94.1%) than the mandible (74.1%). Age at time of extraction and dental developmental stage of the SPM were significant factors for successful spontaneous space closure in the maxilla and mandible, respectively.

Ectopic eruption of maxillary first permanent molars: Risk factors and association with alveolar and maxillary characteristics on children

Background/purposeThe etiology of the ectopic eruption (EE) of the maxillary first permanent molars (FPM) remains unclear and controversial. This study was designed to explore the dental and skeletal factors for EE of the FPM in children. Materials and methodsChildren aged 6–10 years were recruited to this study. Subjects were assigned to the ectopic eruption group (EEG) and the normal eruption group (NEG). Lateral cephalometric radiographs and panoramic radiographs were measured by angular and linear indices. ResultsThe prevalence of EE of maxillary FPM was higher in males and at younger ages. Subjects with skeletal class III malocclusion were more likely to be diagnosed with EE of maxillary FPM. The SNA, ANB, FMIA, Wits, Ptm-A, ANS-PNS, overbite, and overjet were significantly different between the EEG and the NEG. The length of the posterior region of the maxillary alveolar bone, U6-OP, and eruptive angulation of the maxillary FPM were statistically different between the two groups. ConclusionMale sex, skeletal class III malocclusion, mesial inclination of the maxillary FPM, hypoplasia of the maxilla, and insufficient length of the posterior region of the maxillary alveolar bone were related to EE of the maxillary FPM.

Investigation of the causes and pattern of early first permanent molar extraction in children in the western Mediterranean region of Türkiye

Aim: This study aims to investigate the causes and pattern of extraction of first permanent molars (FPMs) in children aged 6-15 years in the western Mediterranean region of Türkiye. Methods: The data from the patients who applied to Department of Pediatric Dentistry, Faculty of Dentistry, Akdeniz University, between the years 2016–2020, were scanned; patients, who had at least one FPM extracted between the ages of 6–15, and who had pre-extraction panoramic radiographs were selected. Information about age, gender, reason for extraction, extracted tooth, and previous treatment status of a total of 562 patients (263 males and 299 females) were recorded. The data were statistically analyzed using chi-square tests. Results: The mean age was 11.87±1.89, and there was no difference between female and male patients (p=0.828). 727 FPMs were evaluated, and the main reason for extraction was detected to be “Excessive substance loss” (55.8%) for both genders in all age groups. The 2nd, 3rd, 4th, and 5th reasons were early FPM extraction, infection, parents’ request, and others respectively. The total number of extracted teeth of female patients was higher (53.6%) than that of males (46.4%) but there was no significant difference. It was observed that mandibular teeth were more frequently extracted than maxillary ones. Most children (75.8%) had one tooth extracted, 19.9% had two teeth, and 3.3% had three teeth. It was determined that the FPMs were not previously treated in the majority of children (90.7%). Conclusions: The most important finding from this study is that most of the extracted FPMs have not been treated previously. This indicates that individuals in our society do not have enough information about and are late in accessing oral health services. Therefore, further steps should be taken to improve public oral health. Keywords: Child; First Permanent Molar; Tooth Extraction

Caries prevalence and molar incisor hypomineralisation (MIH) in children. Is there an association? A systematic review.

Molar incisor hypomeralisation (MIH) is a dental condition clinically characterised by the presence of morphological and qualitative enamel defects involving the occlusal and/or incisal third of one or more permanent molars or incisors. Its worldwide prevalence ranges between 2.4 and 40%. Several harmful conditions, such as genetic or medical problems during pregnancy, may act together and increase the risk of MIH. The main objective of this systematic review is to assess whether there is a correlation between MIH and dental caries in mixed or permanent dentition. An electronic search was performed on PubMed (Medline), Scopus and Cochrane Library for articles published from August 2022 to April 2023. Cohort, cross-sectional, retrospective and prospective studies were included. In vitro and animal studies, as well as clinical cases and systematic reviews, were excluded. Studies not differentiating between mixed and permanent dentition were excluded. The observed variables were DMFT (Decayed Missed Filled Teeth) score, DMFS (Decayed Missed Filled Surface) and DMF scores related to FPM (First Permanent Molar) and the clinical prevalence of MIH. DMFT, DMFS and DMFT on FPM scores are significantly different between the group of patients with MIH and the control group. The available evidence supports a correlation between MIH lesions and caries. Caries indexes scores increase proportionally to the severity of MIH.

Prevalence and Severity of Ectopic Eruption of First Permanent Molars in Pediatric Patients in Makkah, Saudi Arabia.

Background Early detection and management of ectopic eruption (EE) of first permanent molars (FPMs) are crucial to avoid complicated treatments later. Aim This study aimed to assess the prevalence and severity of EE of FPMs among children in Makkah, Saudi Arabia. Methods This retrospective study was based on a radiographic evaluation of 1,008 dental panoramic radiographs performed for children attending the Dental Educational Hospital at Umm Al-Qura University and the Security Forces Hospital in Makkah. Patients' age, sex, tooth location, and severity of EE were assessed. The study adhered to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guideline for cross-sectional studies. Results Of the 1,008 reviewed cases, 18 (1.79%) were diagnosed with EE of FPMs. Among the 11 male patients, 81.82% showed severe EE, while 57.14% exhibited moderately severe EE among the seven female patients. The prevalences of EE in the maxilla and mandible were 1.59% and 0.20%, respectively. In contrast, the occurrence of EE of FPMs was similar between the right and left sides. Conclusion In this study, the prevalence of EE of FPMs among children in Makkah was 1.79%. The frequency and severity were both greater in male patients compared to female patients. While significantly more EE of FPMs was observed in the maxilla than in the mandible, there was no significant difference between the right and left sides.

Outcomes of coronal pulpotomy on permanent first molars in children: a retrospective cohort study.

To investigate the survival probability of permanent first molars (PFMs) after coronal pulpotomy (CP) using two outcome definitions: success-focused and functional survival-focused, and to identify factors influencing tooth survival. A retrospective cohort study reviewing records of children undergoing CP with calcium silicate-based cements (CSCs) on PFMs. Each CP-treated PFM was classified as success, uncertain, failure, or censored. Survival probability was analyzed using Kaplan-Meier estimators. Success-focused definition considered failures and uncertain outcomes as events, while functional survival-focused definition considered only failures as events. Prognostic factors were analyzed using Cox regression analysis. Seventy-seven CP-treated PFMs with a follow-up period of 6-111months. Using the success-focused definition (two failures and 12 uncertain outcomes as events), survival probabilities were 93.1% (95% CI 84.3-97.1%) at 12months, 78.7% (95% CI 65.6-87.3%) at 36months, and 74.9% (95% CI 59.5-89.0%) at 60-111months. However, with the functional survival-focused definition, survival probabilities were 100% at 12months and 96.6% (95% CI 86.9-99.1%) at 24-111months. In multivariable analysis, proximal lesions increased failure risk compared to occlusal lesions (HR 17.17, 95% CI 2.18-135.31, p < 0.01), and resin composite restorations had higher failure risk than stainless steel crowns (HR 13.97, 95% CI 1.49-130.69, p < 0.05). CP using CSCs shows long-term survival potential as an alternative treatment for cariously exposed PFMs in children. Proximal lesions and resin composite restoration could contribute to the lower survival, indicating the need for careful consideration of restoration options and lesion location during treatment planning.