Peripheral Chorioretinal Lesions Research Articles

English

AIM: Study of peripheral retinal degeneration in relation to axial length of eyeball in myopic patient. METHOD: Study of 200 eyes of 100 patients who attended our hospital between 2010-2012.Detailed history was taken in every case. Inclusion criteria were patient with age group of 11years -70years, Patient with myopia. Exclusion criteria were patient with photopsia, history of trauma, diabetes hypertensive and undergone RD surgeries. Vision and refraction with Streak Retinoscopy was done. Axial length was recorded by A-scan biometry. Fundoscopy was done in all cases. RESULT: In our study number of males was 54 and females were 46. Peripheral chorioretinal lesions were noted to be associated with increased axial length of eye 1, 2 .Greater the antero-posterior ocular diameter the greater chance of peripheral chorioretinal degeneration 2 . CONCLUSION: Examination of periphery of retina is important in all myopic cases. Lattice degenerations are most common lesions1, 3. 60% of lesions are found in superotemporal quadrant. Tendency of bilaterality4 is noted in all degenerations except paving stone degeneration. Prevalence of lattice degeneration is maximum in axial length between 28-30mm 5 .

Multifocal choroiditis following simultaneous hepatitis A, typhoid, and yellow fever vaccination

The paper describes the first reported case of multifocal choroiditis following simultaneous hepatitis-A, typhoid, and yellow fever vaccinations. A 33-year-old male developed sudden onset of flashing lights and floaters in his right eye 3 weeks following hepatitis A, typhoid, and yellow fever vaccinations. Fundus examination and angiography confirmed the presence of multiple peripheral chorioretinal lesions. These lesions demonstrated characteristic morphologic changes over a period of 8 weeks which were consistent with a diagnosis of self-resolving multifocal choroiditis. Vaccine-induced intraocular inflammation has been described infrequently. We demonstrate the first case of self-resolving multifocal choroiditis following simultaneous administration of hepatitis A, yellow fever, and typhoid immunizations.

Chorioretinal lesions in mothers of children with congenital toxoplasmosis in the National Collaborative Chicago-based, Congenital Toxoplasmosis Study

AIMS: To determine whether mothers of children with congenital toxoplasmosis have chorioretinal lesions consistent with toxoplasmosis. METHODS: Prospective cohort study. Ophthalmologists in our study have examined 173 children with congenital toxoplasmosis in a hospital outpatient setting. These children were referred to us by their primary care physicians. One hundred and thirty mothers of these children had retina examinations of both eyes at least once. Main outcome measure was lesion(s) consistent with ocular toxoplasmosis. RESULTS: Of 130 mothers examined between 1991-2005, 10 (7.7%, 95% Confidence Interval 3.8%, 13.7%) had chorioretinal lesions which likely represent resolved toxoplasmic chorioretinitis. Most of these were small peripheral chorioretinal lesions. None reactivated between 1991-2005. CONCLUSIONS: Chorioretinal lesions consistent with quiescent ocular toxoplasmosis occur in mothers of children with congenital toxoplasmosis in the United States.

The Role of Chonoretinal Biopsy in the Management of Posterior Uveitis

The ideal management of intraocular inflammation may require a tissue diagnosis. Diagnostic vitrectomy is a well-established method for acquiring such tissue. However, in some patients, the diagnostic pathology is limited to the choroid and retina and vitrectomy may yield no useful information. In such cases, a more aggressive surgical approach to obtain tissue may be useful. The authors performed chorioretinal biopsies on seven patients with progressive chorioretinal lesions of unknown etiology. Indications for biopsy included: (1) macular-threatening lesions unresponsive to therapy, (2) suspicion of malignancy, or (3) suspicion of an infectious etiology. In all cases, it was expected that the results would alter therapy or other aspects of clinical care. Preoperative visual acuity was 20/200 or worse in each eye biopsied with one or more peripheral chorioretinal lesions present. Biopsy specimens were divided into three parts and submitted for light and electron microscopy, immunohistochemistry, and tissue culture. On the basis of the biopsy findings, a diagnosis of multifocal choroiditis and subretinal fibrosis was rendered in three eyes, sarcoidosis in two eyes, and viral retinitis in two eyes. Therapy was changed in five patients. Final visual acuity was unchanged or improved in five eyes. Complications included the progression of lens opacity in all eyes and the development of phthisis in one eye that was extensively diseased preoperatively. Chorioretinal biopsy may provide useful information for determining the diagnosis and guiding the subsequent management of patients with progressive chorioretinal lesions of unknown etiology.

Ophthalmia Nodosa Caused by Tarantula Hairs

A young woman presented with ocular discomfort after handling her pet tarantula; Multiple fine hairs were detected on the eyelids, in the palpebral and bulbar conjunctiva, and in the corneal epithelium and stroma. In addition, foreign body granulomas were found in the conjunctiva. Six months later, peripheral chorioretinal lesions were seen. The clinical and histologic findings in this case closely resemble the findings in ophthalmia nodosa caused by caterpillar hairs.

Electro-ophthalmological responses in inflammations of various sections of the orbital visual pathways (author's transl)

In a study of electro-ophthalmological responses of the EOG, the photopic and scotopic ERG, the OP and the VECP, in combination with fluorescein angiography and computerized perimetry, in 34 patients suffering from uveitis, chorioretinitis (lesions near the macula and at the periphery), papillitis or retrobulbar neuritis, the following results were obtained: Uveitis and chorioretinitis with lesions either near the macula or at the retinal periphery produce different responses; generally, pathologic responses of the EOG and ERG and normal VECP are obtained in cases of uveitis. Peripheral chorioretinal lesions lead to a diminution of the scotopic ERG, OP and EOG, in contrast to lesions near the macula, in which pathologically diminished amplitudes of the photopic ERG and VECP are found. In papillitis and retrobulbar neuritis, however, the most important peculiarity is the increase in latency and the decrease in amplitudes of the VECP, especially in retrobulbar neuritis.

Peripheral Chorioretinal Lesions and Axial Length of the Myopic Eye

A study of the retinal periphery of 1,437 predominantly myopic eyes revealed a statistically significant association of four types of peripheral chorioretinal degenerations with increased axial length of the eye. These were white without pressure, pigmentary degeneration, pavingstone degeneration, and lattice degeneration. There was a tendency for both white without pressure and lattice degeneration jointly to affect eyes of individuals 19 years of age and younger. Increasing age was a significant factor in the incidence of pigmentary and pavingstone degenerations, whereas aging significantly reduced the prevalence of white without pressure.