Exercise Period Research Articles

Biofeedback system in remotely monitored exercise program in pregnant women with obesity: a pre-experimental research

Objectives: E-health programs may be an excellent strategy to overcome some barriers related to the non-practice of exercise among pregnant women with obesity. This study aims to present a monitored exercise program for pregnant women with obesity using the Sword Phoenix® biofeedback system; and to evaluate pregnant women's perception of the biofeedback system and the exercise program protocol. Methods: A pre-experimental research was done through a One-shot case study design. Twelve pregnant women with Body Mass Index ≥ 30 kg/m2, were invited to perform for two weeks a home-based structured exercise program protocol with a digital biofeedback system, during exercise the women used an accelerometer to measure the intensity of the exercises. At the end of the two-week exercise period, the pregnant women filled in a questionnaire to assess their perception of usability, satisfaction, safety and motivation regarding exercise program and biofeedback system. Results: The accelerometry results indicate that, during the exercise program protocol, the pregnant women spent 79.3% of the time in moderate activities. The adherence to the program had an average performance of 40%. The results of the questionnaire demonstrated that 100% (n=12) of the participants enjoyed the system and recognized it as a safe instrument with the potential to increase physical activity during pregnancy. Discussion: The biofeedback system can be a useful tool for implementing an exercise program for pregnant women with obesity. The proposed exercise program complies with international recommendations for physical exercise during pregnancy, ensuring safety. Additionally, it reduces the team intervention, increases participant motivation, and has the potential to reduce sedentary behavior in pregnant women with obesity.

Profiling the lncRNA–miRNA–mRNA interaction network in the cold-resistant exercise period of grape (Vitis amurensis Rupr.)

BackgroundGrape is a plant that is sensitive to low temperature and vulnerable to low-temperature damage. However, little is known about the roles of lncRNAs, miRNAs and mRNAs in regulating the hypothermia response mechanism in Vitis amurensis Rupr.MethodsIn this study, the expression and regulatory network of low-temperature response genes were studied in the phloem of grape under different low-temperature stress.ResultsHere, we performed analyses related to RNA-seq and miRNA-seq on grape phloem tissues from five periods of cold resistance campaigns. Three RNAs (lncRNAs, miRNAs and mRNAs) obtained by KEGG and GO analyses were used to identify starch and sucrose metabolism associated with cold resistance, and specific changes in BP, CC, and MF were identified in four comparisons. Venn diagrams, thermograms and pathway maps were used to analyze the differentially expressed genes (DEGs), and their specific gene expression during the cold exercise were obtained. The six DEGs finally selected were used for qRT-PCR to verify the RNA-seq data. In addition, we found that the regulatory networks of miRNAs and lncRNAs correspond to the six DEGs. This study will contribute to further experimental studies to elucidate the cold resistance mechanism of Vitis amurensis Rupr.ConclusionsThe low-temperature response genes of grape are mainly enriched in the starch and sucrose metabolism, and they are regulated by miRNAs and lncRNAs. The conclusions will provide basic information for further understanding of the cold resistance mechanism of grape in the future.Graphical

A personalized clinical assessment: multi-sensor approach for understanding musculoskeletal health in the frail population

BackgroundSarcopenia is a muscle disorder causing a progressive reduction of muscle mass and strength, but the mechanism of its manifestation is still partially unknown. The three main parameters to assess are: muscle strength, muscle volume or quality and low physical performance. There is not a definitive approach to assess the musculoskeletal condition of frail population and often the available tests to be performed in those clinical bedridden patients is reduced because of physical impairments. In this paper, we propose a novel instrumental multi-domain and non-invasive approach during a well-defined protocol of measurements for overcoming these limitations. A group of 28 bedridden elder people, subjected to surgery after hip fracture, was asked to perform voluntary isometric contractions at the 80% of their maximum voluntary contraction with the non-injured leg. The sensor employed before and/or during the exercise were: ultrasound to determine the muscle architecture (vastus lateralis); force acquisition with a load cell placed on the chair, giving an indication of the muscle strength; surface electromyography (EMG) for monitoring muscular electrical activity; time-domain (TD) near-infrared spectroscopy (NIRS) for evaluating muscle oxidative metabolism.ResultsA personalized “report card” for each subject was created. It includes: the force diagram (both instantaneous and cumulative, expected and measured); the EMG–force diagram for a comparison between EMG derived median frequency and measured force; two graphs related to the hemodynamic parameters for muscle oxidative metabolism evaluation, i.e., oxy-, deoxy-, total-hemoglobin and tissue oxygen saturation for the whole exercise period. A table with the absolute values of the previous hemodynamic parameters during the rest and the ultrasound related parameters are also included.ConclusionsIn this work, we present the union of protocols, multi-domain sensors and parameters for the evaluation of the musculoskeletal condition. The novelties are the use of sensors of different nature, i.e., force, electrical and optical, together with a new way to visualize and combine the results, by means of a concise, exhaustive and personalized medical report card for each patient. This assessment, totally non-invasive, is focused on a bedridden population, but can be extended to the monitoring of rehabilitation progresses or of the training of athletes.

The Effect of Dynamic Warm-Up Exercise Durations on Different Jump Types in Young Male Boxers

This study was conducted to determine the effects of various durations of dynamic warm-up exercise on different jump types in young male boxers. Fourteen young male athletes (mean age: 16.86±1.03 years, height: 172.57±11.34 cm, body weight: 65.21±16.42 kg) voluntarily participated in the study, which employed a pretest-posttest experimental research model, a quantitative method, without a control group. The athletes were instructed to run for 5 minutes at an average heart rate of 120 beats/min, followed by dynamic stretching consisting of 10 different exercises for durations of 5, 10, and 15 minutes on different days. After each period of different dynamic exercises, the participants performed drop jump, countermovement jump, and squat jump tests. The SPSS package program was used to analyze the data obtained from the research. Repeated Measures ANOVA and the Bonferroni test, a post-hoc test, were applied to normally distributed data. Examining the drop jump test results, a significant difference was detected between the various dynamic warm-up times (p < .05), with the distance measured after the 10-minute exercise period higher than those following the 5- and 15-minute warm-up periods. There were no significant differences between the dynamic warm-up times (p ˃ .05) for the countermovement jump and squat jump tests. As a result, dynamic warm-up exercises were determined to improve the drop jump performance of young male boxers, with the 10-minute exercise duration more positively affecting drop jump performance than either the 5- or 15-minute warm-up periods.

Impact of low-to moderate-intensity exercise training on the mRNA expression of purine receptors across various vessels in SHR.

In this study, we developed an exercise training protocol for assessing both blood pressure dynamics and mRNA expression levels of purine receptors in various vascular tissues during physical activity. The objective is to assess the impact of exercise training on blood pressure regulation in spontaneously hypertensive rats (SHR) and purine receptors in vascular tissues. Wistar Kyoto (WKY) and SHR rats were randomly allocated into sedentary (Sed) and exercise training (ExT) groups. Rats in the Sed groups were allowed unrestricted movement, whereas those in the ExT groups underwent a 16-week regimen of low- to moderate-intensity treadmill exercise. Throughout the intervention period, blood pressure measurements and body weight recordings were conducted. Additionally, mRNA expressions of purine receptors P2X1, P2Y1, and P2Y2 in renal artery (RA), internal carotid artery (Int), thoracic aorta (Aor), and caudal artery (Cau) tissues were assessed. In the Sed group, body weight of SHR rats was observed to be lower compared to the three other groups. Over the course of the exercise regimen, blood pressure in the ExT group of SHR rats reduced gradually, converging towards levels similar to those observed in WKY rats by the conclusion of the exercise period. Regarding mRNA expression patterns of P2X1 receptors across the four blood vessels, WKY and SHR rats demonstrated similar sequences, consistently displaying the highest expression levels in the Cau. Conversely, mRNA expressions of P2Y1 and P2Y2 receptors exhibited distinct sequences across the four blood vessels in both WKY and SHR rats. Notably, compared to the Sed group of WKY rats, mRNA expression of P2X1 receptor in the Int of SHR rats revealed an increase, while expressions in the Aor of WKY rats and the Cau of SHR rats decreased following exercise. Expression of P2Y1 receptor mRNA decreased across all four types of blood vessels in SHR rats. Post-exercise, P2Y1 receptor mRNA expression increased in the Aor, decreased in the Cau of WKY rats, and increased in the Int and renal artery (RA) of SHR rats. Conversely, expressions of P2Y2 receptor mRNA decreased in the Int and Aor of SHR rats. Except for the Aor of WKY rats, expressions of P2Y2 receptor mRNA increased in the other arteries of both rat types following exercise. Differences in the distribution of purine receptor subtypes among distinct arterial segments in both WKY and SHR rats were observed. Exercise training was found to enhance mRNA expression levels of P2Y receptors in these rat models. This finding implies that exercise training might reduce hypertension in SHR rats by bolstering the purinergic relaxation response.

Genome-wide association study of exercise-induced skeletal muscle hypertrophy and the construction of predictive model.

The aim of the current study was to investigate interindividual differences in muscle thickness of the rectus femoris (MTRF) following 12 wk of resistance training (RT) or high-intensity interval training (HIIT) to explore the genetic architecture underlying skeletal muscle hypertrophy and to construct predictive models. We conducted musculoskeletal ultrasound assessments of the MTRF response in 440 physically inactive adults after the 12-wk exercise period. A genome-wide association study was used to identify variants associated with the MTRF response, separately for RT and HIIT. Using the polygenic predictor score (PPS), we estimated the genetic contribution to exercise-induced hypertrophy. Predictive models for the MTRF response were constructed using random forest (RF), support vector mac (SVM), and generalized linear model (GLM) in 10 cross-validated approaches. MTRF increased significantly after both RT (8.8%, P < 0.05) and HIIT (5.3%, P < 0.05), but with considerable interindividual differences (RT: -13.5 to 38.4%, HIIT: -14.2 to 30.7%). Eleven lead single-nucleotide polymorphisms in RT and eight lead single-nucleotide polymorphisms in HIIT were identified at a significance level of P < 1 × 10-5. The PPS was associated with the MTRF response, explaining 47.2% of the variation in response to RT and 38.3% of the variation in response to HIIT. Notably, the GLM and SVM predictive models exhibited superior performance compared with RF models (P < 0.05), and the GLM demonstrated optimal performance with an area under curve of 0.809 (95% confidence interval: 0.669-0.949). Factors such as PPS, baseline MTRF, and exercise protocol exerted influence on the MTRF response to exercise, with PPS being the primary contributor. The GLM and SVM predictive model, incorporating both genetic and phenotypic factors, emerged as promising tools for predicting exercise-induced skeletal muscle hypertrophy.NEW & NOTEWORTHY The interindividual variability induced muscle hypertrophy by resistance training (RT) or high-intensity interval training (HIIT) and the associated genetic architecture remain uncertain. We identified genetic variants that underlie RT- or HIIT-induced muscle hypertrophy and established them as pivotal factors influencing the response regardless of the training type. The genetic-phenotype predictive model developed has the potential to identify nonresponders or individuals with low responsiveness before engaging in exercise training.

The effects of an 8-week dynamic neuromuscular stabilization exercise on pain, functional disability, and quality of life in individuals with non-specific chronic low back pain: a randomized clinical trial with a two-month follow-up study

BackgroundLow back pain (LBP) is a common disorder and is considered one of the leading causes of disability worldwide, resulting in adverse health, social, and economic outcomes. This study aimed to investigate the effects and durability of 8-week Dynamic Neuromuscular Stabilization (DNS) exercises on pain, functional disability, and quality of life in individuals aged 30 to 50 years with non-specific chronic low back pain (NSCLBP).MethodsThis research employed a pre- and post-test design with a follow-up period, in which 29 participants (16 in the control group and 13 in the exercise group) remained until the end of the study. Pain intensity, functional disability, and quality of life were assessed using the visual analog scale (VAS), the Oswestry Disability Index, and the SF-36 questionnaire, respectively, before intervention, immediately after, and two months post-intervention. The control group continued their routine daily activities, while the exercise group performed DNS exercises three times a week for 8 weeks. The data was analyzed using a mixed-design ANOVA (P ≤ 0.05).ResultsThe results showed improvements in pain (F (2,24) = 5.31, P = 0.01, η2 = 0.31), functional disability (F (2,24) = 4.17, P = 0.03, η2 = 0.26), and quality of life (F (2,24) = 4.70, P = 0.02, η2 = 0.28) in the exercise group at the Post-test compared to the Pre-test. However, the durability of the exercise effects at the follow-up assessment was not sustainable compared to the Post-test and Pre-test (P > 0.05).ConclusionAn 8-week period of DNS exercises can improve pain, functional disability, and quality of life in individuals with NSCLBP. However, a 2-month period of detraining can reduce the positive outcomes of these exercises.Trial registrationThe researchers retrospectively registered this trial on 21/04/2024, with the identifier IRCT20240107060646N1 in the Iranian Registry of Clinical Trials (IRCT) at the following address: https://irct.behdasht.gov.ir.

Attenuation of Delayed Onset Muscle Soreness with Acute Consumption of Essential Amino Acids

Introduction: Prior studies of the acute benefits of protein supplementation have determined a benefit in improving post-exercise muscle anabolism and aiding the recovery of muscle function and performance. Previous acute protein supplement studies in post-exercise protein synthesis and anabolic intracellular signaling reported no attenuation in muscle damage or elevated muscle function. The aim of this study is to implement a specific content of essential amino acids with resistance and aerobic exercises to quantify the difference in strength, endurance, and flexibility during the delayed onset muscle soreness common with a new exercise protocol. Methods: We enrolled 42 participants (22 EAA and 20 Controls) completed an hour-long aerobic and resistance exercise protocol including flexibility, resistance, and aerobic exercises for three consecutive days. The study participants were randomly assigned to the EAA (6.6g) per day (EAA + Gatorade) group or the control (Gatorade) group. The data was analyzed in a double-blinded format. Results: Both groups improved the initial flexibility respectively throughout the three exercise days but were not significantly different (p=0.32) in the sit and reach. For the resistance/power activities, the EAA group improved in the repetitions for push-ups (p=0.014 vs 0.21) and dips (0.0002 vs 0.59) compared to the controls. The EAA group was faster although not statistically significant in the 20-meter sprint and improved in the 1.5-mile run during the third day (P=0.002 vs 0.48) compared to the control group. Conclusions: The data in the results supports that acute ingestion of the essential amino acid supplements provides increased physical performance and decreases the DOMS symptoms in sedentary participants over the three-day trial period of exercise.

Exploring the Acute Effects of Immersive Virtual Reality Biking on Self-Efficacy and Attention of Individuals in the Treatment of Substance Use Disorders: A Feasibility Study.

The role of exercise programs during substance use disorder (SUD) treatment is considered particularly supportive in fostering positive psychological and behavioral changes. The treatment of SUD is a challenging and demanding process. Therefore, it is crucial to discover innovative methods to enhance and facilitate it. Integrating exercise into a virtual environment is an innovative approach for drug rehabilitation, offering multiple benefits to individuals undergoing treatment. The aim of this feasibility study was to explore the acute effects of cycling exercise in an immersive virtual reality (VR) environment on attentional control and self-efficacy expectations of individuals undergoing SUD treatment. A total of 20 individuals (mean age of 37.75 years) enrolled in a SUD treatment program participated in the study. They were instructed to complete a single session of cycling with a self-selected duration within the VR system. Following the cycling session, pre-post measures indicated a statistically significant improvement in self-efficacy expectations and attentional control measured with the Stroop test. The results revealed that participants expressed high levels of intention for future use, interest/enjoyment, and positive attitudes toward the VR exercise system. Qualitative data indicated that participants found the VR exercise system enjoyable, expressed a strong intention to use it, and did not encounter technical difficulties or negative emotions. In conclusion, it seems that engaging in a brief period of self-selected exercise within a virtual environment can result in temporary activation of cognitive changes, heightened self-efficacy expectations, and a motivating approach to increasing physical activity participation among individuals with SUD, thus suggesting the feasibility of this approach.

Preconception Physical Exercise Is Associated with Phenotype-Specific Cardiovascular Alterations in Women at Risk for Gestational Hypertensive Disorders.

Background/Objectives: Gestational hypertensive disorders (GHD) pose significant maternal and fetal health risks during pregnancy. Preconception physical exercise has been associated with a lower incidence of GHD, but insights into the cardiovascular mechanisms remain limited. This study aimed to evaluate the effect of preconception physical exercise on the complete cardiovascular functions of women at risk for GHD in a subsequent pregnancy. Methods: A non-invasive hemodynamics assessment of arteries, veins, and the heart was performed on 40 non-pregnant women at risk for developing GHD in a subsequent pregnancy. Measurements of an electrocardiogram Doppler ultrasound, impedance cardiography and bio-impedance spectrum analysis were taken before and after they engaged in physical exercise (30-50 min, 3×/week, 4-6 months). Results: After a mean physical exercise period of 29.80 weeks, the total peripheral resistance (TPR), diastolic blood pressure and mean arterial pressure decreased in the total study population, without changing cardiac output (CO). However, in 42% (9/21) of women categorized with high or low baseline CO (>P75 or <P25 resp.), a shift in CO was observed towards the normal reference interquartile range (P25-P75). This was associated with improved hepatic venous and central arterial hemodynamic functions. Similar changes in TPR occurred in 38% (11/29) of women classified as having low or high baseline TPR. Conclusions: As in pregnancy, output- or resistance-dominant cardiovascular profiles already exist prior to conception. This study illustrates that preconception physical exercise shifts high or low CO and/or TPR towards the normal midrange, allowing women at risk for GHD to start a subsequent pregnancy with a more gestation-adaptable cardiovascular system.

Interval training and cardiometabolic health in reproductive-aged females.

Physical activity and exercise training are especially important for reproductive-aged females as exercise-induced health benefits can also affect their infants. However, levels of physical inactivity remain high among females in this age group, before, during, and after pregnancy. There is a great need for practical and feasible exercise modes to increase adherence to exercise in this population, and interval training may be a time-efficient training modality. Interval training is a form of exercise involving intermittent bouts of intense effort interspersed with recovery periods of rest or lower-intensity exercise. A substantial amount of research indicates that interval training induces superior cardiometabolic health benefits compared with iso-energetic moderate-intensity continuous exercise. This review provides a comprehensive overview of research on interval training interventions in reproductive-aged females across various life stages, focusing on the cardiometabolic health benefits. We discuss the potential role of interval training in premenopausal females with overweight/obesity, polycystic ovary syndrome, and subfertility, as well as the potential influence of oral contraceptives on cardiometabolic adaptations to interval training. Furthermore, this review also highlights recent findings supporting the beneficial role of high-intensity interval training for cardiometabolic health outcomes during pregnancy. In summary, the existing evidence suggests that interval training can improve several cardiometabolic and reproductive outcomes in females spanning different life stages. However, more research is needed to further strengthen the evidence-base for physical activity recommendations for females in their reproductive years of life.

The Effects of High-Intensity Interval Training (HIIT) on Ovarian Function and Fertility Potential in Women

Background: High-Intensity Interval Training (HIIT) has recently been recognized as one of the regimens encompassing various benefits for maintaining health across diverse populations. It is based on intense exercise with brief periods of rest or low-intensity activity, offering a time-efficient approach that appeals to individuals seeking maximal benefits with minimal time commitment. Methodology: Women aged 18-40 years with regular menstrual cycles and sedentary or moderately active lifestyles attending outpatient physiotherapy clinics in Lahore were divided into HIIT groups which engaged in supervised sessions for 4 days/week for 12 weeks, performed alternating periods of high-intensity exercise on a stationary bike for 1 minute with periods of active recovery for 30 seconds at 80-90% THR. Participants in the control group performed supervised aerobic exercise sessions 5 days/week for 12 weeks and performed moderate-intensity continuous exercises on a stationary cycle at 70-75% THR for 30 minutes. The hormonal markers and the regularity of menstruation were assessed at baseline and post-intervention. Results: Within-group analysis showed a notable increment in the level of estradiol and progesterone in both groups (p&lt;0.05). Between-group analysis also exposed the HIIT group as being superior to the aerobic. (p&lt;0.001). Conclusion: The findings of the study demonstrated the effectiveness of HIIT and aerobic exercise in impacting the hormonal markers and the regularity of menstruation among obese women. Although, the HIIT showed greater efficacy in improvising estradiol and progesterone levels and reducing menstrual cycle length. Keywords: Aerobic Exercise, Fertility, Interval Training, Obesity.

An Analysis of the Effectiveness of Strengthening or Stretching Exercises in Patients Performing Prolonged Sedentary Work with Non-Specific Lower Back Pain.

Non-specific LBP refers to back pain which arises from the spine, intervertebral discs and surrounding soft tissues in the absence of pathologic lesions. Most cases of non-specific LBP are not the result of a single injury from a high load, but the result of repetitive, cumulative micro-injuries. The aim of the study was to assess the effectiveness of strengthening, stretching and mixed exercises in patients with non-specific LBP and their impact on pain intensity. We analysed 90 patients with non-specific LBP who performed prolonged sedentary work. Patients were qualified following history-taking, a physical examination and radiological evaluation if no pathology had been revealed on examination or on the available diagnostic imaging scans. The participants were randomly divided into 3 groups of 30 individuals each. The patients in each group performed one type of exercise (strengthening, stretching, mixed) for a period of 3 months. Both before starting and on completion of the exercise period, the patients were assessed with an original questionnaire as well as the Rolland-Morris, Oswestry and SF-12 scoring systems. Strengthening exercises were the most effective in reducing pain; on completion of the exercise period, pain assessed with the NRS scale was 2 points in the strengthening exercise group, 3 points, in the mixed group, and 4 points in the stretching group. The SF-12 questionnaire showed an improvement in the patients' health (increase in "excellent" and "very good" scores from 7% to 60%). According to the Oswestry disability questionnaire, strengthening exercises were the most effective (mean disability score of 4). 1. The use of strengthening exercises in patients with non-specific LBP most effectively improves function and reduces back pain. 2. The use of stretching and mixed exercises in patients with non-specific LBP improves function and reduces back pain, but to a lesser extent than strengthening exercises.

직장인의 운동 참여에 따른 감성지능, 회복탄력성, 정신적 웰빙, 지각된 스트레스, 직장 생활 만족도 차이 검증

Objectives This study examined the differences in emotional intelligence, resilience, mental well-being, perceived stress, and job satisfaction depending on the exercise participation of office workers. Methods This study targeted subjects who worked as office workers in 2022, distributed and collected 1024 copies of the questionnaire, and used a total of 881 of them after excluding 143 copies with incomplete responses and problems. This study used SPSS 26 and AMOS 26 for frequency analysis, reliability analysis, confirmatory factor analysis, independent t-test, one-way ANOVA, and multivariate analysis (MANOVA). Results According to analysis on gender differences, men showed higher self-emotion awareness, emotion control, emotion utilization, resilience, social well-being, and positive perception than women. Meanwhile, women showed higher awareness of other's emotion and negative perception than men. The analysis on exercise participation status, exercise degree, and exercise intensity showed that the groups of exercise participation, groups of moderate and frequent exercise, and groups of moderate to intense exercise demonstrated higher scores in psychological factors. In the analysis on exercise participation period, the groups of exercise periods less than 10 years showed higher emotional control, while groups of exercise periods longer than 10 years exhibited higher psychological well-being and resilience than other groups. For differences in type of exercise, the groups of skill sports showed a higher positive perception than the groups of conquest sports. Conclusions The analysis results showed that exercise participation relieved the factors that negatively affect the mental health of office workers, while improving the positive factors. Thus, it is necessary to actively encourage exercise participation at the individual, corporate, and national levels to improve the mental health and job performance of office workers.

Multilayer Perceptron-Based Wearable Exercise-Related Heart Rate Variability Predicts Anxiety and Depression in College Students.

(1) Background: This study aims to investigate the correlation between heart rate variability (HRV) during exercise and recovery periods and the levels of anxiety and depression among college students. Additionally, the study assesses the accuracy of a multilayer perceptron-based HRV analysis in predicting these emotional states. (2) Methods: A total of 845 healthy college students, aged between 18 and 22, participated in the study. Participants completed self-assessment scales for anxiety and depression (SAS and PHQ-9). HRV data were collected during exercise and for a 5-min period post-exercise. The multilayer perceptron neural network model, which included several branches with identical configurations, was employed for data processing. (3) Results: Through a 5-fold cross-validation approach, the average accuracy of HRV in predicting anxiety levels was 89.3% for no anxiety, 83.6% for mild anxiety, and 74.9% for moderate to severe anxiety. For depression levels, the average accuracy was 90.1% for no depression, 84.2% for mild depression, and 82.1% for moderate to severe depression. The predictive R-squared values for anxiety and depression scores were 0.62 and 0.41, respectively. (4) Conclusions: The study demonstrated that HRV during exercise and recovery in college students can effectively predict levels of anxiety and depression. However, the accuracy of score prediction requires further improvement. HRV related to exercise can serve as a non-invasive biomarker for assessing psychological health.

Ten-Minute Physical Activity Breaks Improve Attention and Executive Functions in Healthcare Workers.

Occupational health is a major problem in modern work environments. Physical activity breaks (PABs), short exercise periods delivered during working hours, incorporating exergames or outdoor activities, have emerged as a novel approach that could be used to improve work efficiency and workplace wellbeing. Therefore, this study aimed to investigate the impact of PABs on attention levels and executive functions in healthcare workers. A total of 27 healthcare workers (M = 14, W = 13; 49.55 ± 12.46 years), after 4 h of work, randomly performed one of three 10 min conditions weekly in a counterbalanced order: No Physical Activity Break (NPAB); Outdoor Physical Activity Break (OPAB); Physical Activity Break with Exergame (PABEx). After the conditions, executive functions and selective attention were assessed by the Stroop Color and Word Test (SCWT), and the Trail Making A,B test (TMT A,B), respectively. Significant differences between OPAB and NPAB as well as between PABEx and NPAB in the TMT-A test χ2(2) = 44.66 (p < 0.001) and TMT-B test χ2(2) = 48.67 (p < 0.001) were found, respectively. TMT-A and SCWT interference/time scores of the PABEx and OPAB conditions were significantly lower than those of NPAB (p < 0.001). In the SCWT interference/error score, no significant difference was found between the PABEx and NPAB (p > 0.05), but the score was statistically lower in the OPAB condition than PABEx (p = 0.001) and PABEx condition compared to OPAB for TMT-A (p = 0.001). Findings showed that the OPAB and PABEx conditions are effective in improving selective attention and executive functions in healthcare workers. Employers can foster a healthier and more productive workforce by promoting a culture of movement and prioritizing employee health, which in turn can enhance patient care outcomes.

Executive equity incentives and corporate digital transformation

Based on a sample of Chinese A-share listed companies from 2005 to 2021, we explore the impact of executive equity incentives on corporate digital transformation. We find that executive equity incentives promote corporate digital transformation, and this effect is more salient for equity incentives granted in the form of stock options than restricted stocks, with a longer exercise period, and more lenient exercise performance conditions. Our findings enrich the research on the economic consequences of executive equity incentives and provide insights for promoting corporate digital transformation.

Detraining after short-term exercise induces hyperphagia and obesity with fatty liver and brown adipose tissue whitening in young male OLETF rats.

This study examined the effects of exercise and detraining at a young age on fat accumulation in various organs. Four-week-old male Otsuka Long-Evans Tokushima Fatty (OLETF) rats were assigned to either the non-exercise sedentary (OLETF Sed) or exercise groups. The exercise group was subdivided into two groups: exercise between 4 and 12 weeks of age (OLETF Ex) and exercise between 4 and 6 weeks of age followed by non-exercise between 6 and 12 weeks of age (OLETF DT). Body weight was significantly lower in the OLETF Ex group than in the OLETF Sed group at 12 weeks of age. Fat accumulation in the epididymal white adipose tissue, liver, and brown adipose tissue was suppressed in the OLETF Ex group. During the exercise period, body weight and food intake in the OLETF DT group were significantly lower than those in the OLETF Sed group. However, food intake was significantly higher in the OLETF DT group than in the OLETF Sed group after exercise cessation, resulting in extreme obesity with fatty liver and brown adipose tissue whitening. Detraining after early-onset exercise promotes hyperphagia, causing extreme obesity. Overeating should be avoided during detraining periods in cases of exercise cessation at a young age.

Effects of different exercise modes and intensities on cognitive performance, adult hippocampal neurogenesis, and synaptic plasticity in mice.

Exercise can induce beneficial improvements in cognition. However, the effects of different modes and intensities of exercise have yet to be explored in detail. This study aimed to identify the effects of different exercise modes (aerobic and resistance) and intensities (low and high) on cognitive performance, adult hippocampal neurogenesis and synaptic plasticity in mice. A total of 40 C57BL/6J mice were randomised into 5 groups (n = 8 mice per group): control, low-intensity aerobic exercise, high-intensity aerobic exercise, low-intensity resistance exercise, and high-intensity resistance exercise. The aerobic exercise groups underwent treadmill training, while the resistance exercise groups underwent ladder climbing training. At the end of the exercise period, cognitive performance was assessed by the Y-maze and Barnes maze. In addition, adult hippocampal neurogenesis was evaluated immunohistochemically by 5-bromo-2'-deoxyuridine (BrdU)/ neuronal nuclei (NeuN) co-labeling. The levels of synaptic plasticity-related proteins in the hippocampus, including synaptophysin (SYP) and postsynaptic density protein 95 (PSD-95), were analyzed by western blotting. Our results showed no significant differences in cognitive performance among the groups. However, high-intensity aerobic exercise significantly increased hippocampal adult neurogenesis relative to the control. A trend towards increased adult neurogenesis was observed in the low-intensity aerobic group compared to the control group. No significant changes in synaptic plasticity were observed among all groups. Our results indicate that high-intensity aerobic exercise may be the most potent stimulator of adult hippocampal neurogenesis.

Impact of squat set configuration on mechanical performance in paired sets of upper-body exercises.

Paired sets and alternative set configurations (e.g., cluster sets) are frequently employed by strength and conditioning practitioners; however, their synergistic impact remains underexplored in research. This study aimed to elucidate whether the set configuration used in a lower-body exercise affects mechanical performance during paired sets of upper-body exercises. Twenty-one resistance-trained individuals (14 men and 7 women) randomly completed three experimental sessions that involved four sets of five repetitions at 75%1RM during both the bench press and bench pull exercises. The three experimental sessions varied solely in the activity conducted during the inter-set rest periods of each upper-body exercise: (i) Traditional squat - six squat repetitions without intra-set rest at 65%1RM; (ii) Rest redistribution squat - two clusters of three repetitions of the squat exercise at 65%1RM with 30s of intra-set rest; and (iii) Passive rest - no exercise. The rest redistribution set configuration allowed the sets of the squat exercise to be performed at a faster velocity than the traditional set configuration (p = 0.037). However, none of the mechanical variables differed between the exercise protocols neither in the bench press (p ranged from 0.279 to 0.875) nor in the bench pull (p ranged from 0.166 to 0.478). Although rest redistribution is an effective strategy to alleviate fatigue during the sets in which it is implemented, it does not allow subjects to perform better in subsequent sets of the training session.