Background: The background of the study is the incidence of Movement restriction among Periarthritis subjectswhich affects the Pressure pain threshold and Functional activity of the shoulder.Purpose: To compare the effectiveness of shoulder strengthening exercises in patients with Periarthritis Shoulder.To evaluate the effect of pain and functional activity by pressure algometer and SPADI.Materials and methods: The two groups; Group-A (Mulligan Mobilisation with Movement) and Group-B(Shoulder strengthening exercises) were randomly assigned. The pre-test assesses Pressure Pain Threshold byutilising a pressure algometer and Shoulder Pain and Disability Index (SPADI) Questionnaires to assess ShoulderFunctional Activity among periarthritis shoulder in both the groups. The Group-A(MWM) has received MulliganMobilisation with Movement for a period of 4 weeks. In contrast to Group-B,which has received shoulderstrengthening exercises for periarthritis shoulder.The same tests were measured after 4 weeks of treatment aspost-test values.Results: The pretest and post test values significant difference (p<0.0001)between groups A(MWM) and B(Shoulderstrengthening exercises).The study showed that MWM has a major impact on recovery of PPT and Functionalactivity affected in Periarthritis shoulder participants.Conclusion: The Mulligan mobilisation with movement was effective on improving the Functional activity andreduction in pressure pain threshold.