Atakpamé is made up of urban and peri-urban (slum) neighborhoods. For urban and peri-urban populations, opportunity costs are high, deprivation is enormous particularly among peri-urban communities, recent arrivals are likely to lack health services yet the technology and strategies to reach these populations are available and effective (Unicef, 2018). According to the same source, there are growing disparities in vaccination coverage between rich and poor in the city, with coverage lower among the poor. The city is also the outbreak point for outbreaks, especially in peri-urban areas where highly mobile, poor populations live (WHO, 2017). High population density and promiscuity increase the spread of epidemics. As the city of Atakpamé has a uniquely diverse internal population, specific strategies and targeted interventions were developed with stakeholders. In order to better understand the specific realities, the process included a situational analysis of immunization data, incorporated prioritization of areas and coordination by district and local representatives to ensure that the strategy put in place is operational. This operational research aims to show the effect of the reach-every-child strategy on vaccination coverage for the second dose of measles-rubella vaccine.