Performance Of Recognition Memory Task Research Articles

6- to 10-year-old children do not show race-based orienting biases to faces during an online attention capture task

Research has established that frequency of exposure to own- and other-race faces shapes the development of face processing biases characterized by enhanced attention to and recognition of more familiar own-race faces, that is, the other-race effect (ORE). The ORE is first evident during infancy based on differences in looking to own- versus other-race faces and is later assessed based on recognition memory task performance during childhood and adulthood. Using these measures, researchers have found that race-based face processing biases initially develop during infancy but remain sensitive to experiences with own- and other-race faces through childhood. In contrast, limited work suggests that infants’ attention orienting may be less affected by frequency of exposure to own- and other-race faces. However, the plasticity of race-based face processing biases during childhood suggests that biased orienting to own-race faces may develop at later ages following continued exposure to these faces. We addressed this question by examining 6- to 10-year-old children’s attention capture by own- and other-race faces during an online task. Children searched for a target among multiple distractors. During some trials, either an own- or other-race face appeared as one of the distractors. Children showed similar target detection performance (omission errors, accuracy, and response times) regardless of whether an own- or other-race face appeared as a distractor. These results differ from research demonstrating race-based biases in attention holding and recognition memory but converge with previous infant research suggesting that attention orienting might not be as strongly affected by frequency of exposure to race-based information during development.

Mapping Pitch Accents to Memory Representations in Spoken Discourse Among Chinese Learners of English: Effects of L2 Proficiency and Working Memory.

We examined L2 learners’ interpretation of pitch accent cues in discourse memory and how these effects vary with proficiency and working memory (WM). One hundred sixty-eight L1-Chinese participants learning L2-English listened to recorded discourses containing pairs of contrastive alternatives and then took a later recognition memory test. Their language proficiency and WM were measured through standard tests and the participants were categorized into low, medium, advanced, and high advanced language proficiency groups. We analyzed recognition memory task performance using signal detection theory to tease apart response bias (an overall tendency to affirm memory probes) from sensitivity (the ability to discern whether a specific probe statement is true). The results showed a benefit of contrastive L + H* pitch accents in rejecting probes referring to items unmentioned in a discourse, but not contrastive alternatives themselves. More proficient participants also showed more accurate memory for the discourses overall, as well as a reduced overall bias to affirm the presented statements as true. Meanwhile, that the benefit of L + H* accents in rejecting either contrast probes or unmentioned probes was modulated for people with greater working memory. Participants with higher WM were quite sure that it did not exist in the memory trace as this part of discourse wasn’t mentioned. The results support a contrast-uncertainty hypothesis, in which comprehenders recall the contrast set but fail to distinguish which is the correct item. Further, these effects were influenced by proficiency and by working memory, suggesting they reflect incomplete mapping between pitch accent and discourse representation.

ROC Modelling Data of the Word Frequency Effect: A Formal Model of Visual Word Recognition

This article presents a formal statistical model for assessing the word frequency effect in recognition memory. This topic is relevant because word frequency is the best predictor of performance in recognition memory tasks. Signal Detection Theory was applied using high-frequency and low-frequency words as item-signals. Signal Detection Theory test assumes orthogonality of responses: hits, false alarms, correct rejections, and incorrect rejections. Ninety-six adult male and female students participated in two experiments: one conducted in the laboratory and the other in the class-room. The selected words for memory contained 3 to 5 letters and 1 or 2 syllables to control for length. Significant differences were found between high-frequency and low-frequency words in the number of false alarms for the two experiments. The differences were statistically significant in two experiments. The Cohen effect size was 0.6 and 0.45 respectively. The word frequency effect in first- and second-experiments was F (1, 46) = 4.13, MCE. = 2.34, p = 0.003 and F (1, 46) = 3.71, MCE. = 12.36, p = 0. 01 respectively. A formal model is presented based on the Receiver Operating Characteristic data to assess data trends for high- and low frequency words. Two differentiated models were obtained: a continuous model based on high frequency stimuli and a threshold model based on low frequency stimuli.

A multimodal imaging study of recognition memory in very preterm born adults.

Very preterm (<32 weeks of gestation) birth is associated with structural brain alterations and memory impairments throughout childhood and adolescence. Here, we used functional MRI (fMRI) to study the neuroanatomy of recognition memory in 49 very preterm‐born adults and 50 controls (mean age: 30 years) during completion of a task involving visual encoding and recognition of abstract pictures. T1‐weighted and diffusion‐weighted images were also collected. Bilateral hippocampal volumes were calculated and tractography of the fornix and cingulum was performed and assessed in terms of volume and hindrance modulated orientational anisotropy (HMOA). Online recognition memory task performance, assessed with A scores, was poorer in the very preterm compared with the control group. Analysis of fMRI data focused on differences in neural activity between the recognition and encoding trials. Very preterm born adults showed decreased activation in the right middle frontal gyrus and posterior cingulate cortex/precuneus and increased activation in the left inferior frontal gyrus and bilateral lateral occipital cortex (LOC) compared with controls. Hippocampi, fornix and cingulum volume was significantly smaller and fornix HMOA was lower in very preterm adults. Among all the structural and functional brain metrics that showed statistically significant group differences, LOC activation was the best predictor of online task performance (P = 0.020). In terms of association between brain function and structure, LOC activation was predicted by fornix HMOA in the preterm group only (P = 0.020). These results suggest that neuroanatomical alterations in very preterm born individuals may be underlying their poorer recognition memory performance. Hum Brain Mapp 38:644–655, 2017. © 2016 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

PM535. The effect of bilateral saccadic eye movements on the performance of recognition memory task in patients with schizophrenia

PM535. The effect of bilateral saccadic eye movements on the performance of recognition memory task in patients with schizophrenia

Optogenetic Stimulation of Prefrontal Glutamatergic Neurons Enhances Recognition Memory.

Finding effective cognitive enhancers is a major health challenge; however, modulating glutamatergic neurotransmission has the potential to enhance performance in recognition memory tasks. Previous studies using glutamate receptor antagonists have revealed that the medial prefrontal cortex (mPFC) plays a central role in associative recognition memory. The present study investigates short-term recognition memory using optogenetics to target glutamatergic neurons within the rodent mPFC specifically. Selective stimulation of glutamatergic neurons during the online maintenance of information enhanced associative recognition memory in normal animals. This cognitive enhancing effect was replicated by local infusions of the AMPAkine CX516, but not CX546, which differ in their effects on EPSPs. This suggests that enhancing the amplitude, but not the duration, of excitatory synaptic currents improves memory performance. Increasing glutamate release through infusions of the mGluR7 presynaptic receptor antagonist MMPIP had no effect on performance.SIGNIFICANCE STATEMENT These results provide new mechanistic information that could guide the targeting of future cognitive enhancers. Our work suggests that improved associative-recognition memory can be achieved by enhancing endogenous glutamatergic neuronal activity selectively using an optogenetic approach. We build on these observations to recapitulate this effect using drug treatments that enhance the amplitude of EPSPs; however, drugs that alter the duration of the EPSP or increase glutamate release lack efficacy. This suggests that both neural and temporal specificity are needed to achieve cognitive enhancement.

Effect of general anesthesia in infancy on long-term recognition memory in humans and rats.

Anesthesia in infancy impairs performance in recognition memory tasks in mammalian animals, but it is unknown if this occurs in humans. Successful recognition can be based on stimulus familiarity or recollection of event details. Several brain structures involved in recollection are affected by anesthesia-induced neurodegeneration in animals. Therefore, we hypothesized that anesthesia in infancy impairs recollection later in life in humans and rats. Twenty eight children ages 6-11 who had undergone a procedure requiring general anesthesia before age 1 were compared with 28 age- and gender-matched children who had not undergone anesthesia. Recollection and familiarity were assessed in an object recognition memory test using receiver operator characteristic analysis. In addition, IQ and Child Behavior Checklist scores were assessed. In parallel, thirty three 7-day-old rats were randomized to receive anesthesia or sham anesthesia. Over 10 months, recollection and familiarity were assessed using an odor recognition test. We found that anesthetized children had significantly lower recollection scores and were impaired at recollecting associative information compared with controls. Familiarity, IQ, and Child Behavior Checklist scores were not different between groups. In rats, anesthetized subjects had significantly lower recollection scores than controls while familiarity was unaffected. Rats that had undergone tissue injury during anesthesia had similar recollection indices as rats that had been anesthetized without tissue injury. These findings suggest that general anesthesia in infancy impairs recollection later in life in humans and rats. In rats, this effect is independent of underlying disease or tissue injury.

Déjà vu experiences in healthy subjects are unrelated to laboratory tests of recollection and familiarity for word stimuli

Recent neuropsychological and neuroscientific research suggests that people who experience more déjà vu display characteristic patterns in normal recognition memory. We conducted a large individual differences study (n = 206) to test these predictions using recollection and familiarity parameters recovered from a standard memory task. Participants reported déjà vu frequency and a number of its correlates, and completed a recognition memory task analogous to a Remember-Know procedure. The individual difference measures replicated an established correlation between déjà vu frequency and frequency of travel, and recognition performance showed well-established word frequency and accuracy effects. Contrary to predictions, no relationships were found between déjà vu frequency and recollection or familiarity memory parameters from the recognition test. We suggest that déjà vu in the healthy population reflects a mismatch between errant memory signaling and memory monitoring processes not easily characterized by standard recognition memory task performance.

Dysfunctional and compensatory duality in mild cognitive impairment during a continuous recognition memory task

One of the current issues of debate in the study of mild cognitive impairment (MCI) is deviations of oscillatory brain responses from normal brain states and its dynamics. This work aims to characterize the differences of power in brain oscillations during the execution of a recognition memory task in MCI subjects in comparison with elderly controls. Magnetoencephalographic (MEG) signals were recorded during a continuous recognition memory task performance. Oscillatory brain activity during the recognition phase of the task was analyzed by wavelet transform in the source space by means of minimum norm algorithm. Both groups obtained a 77% hit ratio. In comparison with healthy controls, MCI subjects showed increased theta (p<0.001), lower beta reduction (p<0.001) and decreased alpha and gamma power (p<0.002 and p<0.001 respectively) in frontal, temporal and parietal areas during early and late latencies. Our results point towards a dual pattern of activity (increase and decrease) which is indicative of MCI and specific to certain time windows, frequency bands and brain regions. These results could represent two neurophysiological sides of MCI. Characterizing these opposing processes may contribute to the understanding of the disorder.

The Influence of Bilateral Eye Movement on Recognition Memory Task Performance

Bo-Ra Lee, MD, Ji-Woong Kim, MD, PhD, Suk-Won Kwon, PhD, Hyuk-Chan Kwon, PhD, Ki-Woong Kim, PhD, Min-Young Kim, PhD, Ji-Eun Kim, MS, Kwon-Kyu Yu, MS, Yong-Ho Lee, PhD and Sang-Hyun Lim, MS 1 Department of Psychiatry, Konyang University College of Medicine, Konyang University Hospital, Daejeon, Korea 2 Brain and Cognition Measurement Laboratory, Division of Convergence Technology, Korea Research Institute of Standards and Science, Daejeon, Korea Department of Medical Physics, University of Science and Technology, Daejeon, Korea

A novel delayed non-match to sample object recognition task that allows simultaneous in vivo microdialysis

We present a modification of the widely used delayed non-match to sample (DNMS) paradigm for assessment of object recognition memory that can be combined with simultaneous in vivo microdialysis. The present study provides evidence that hippocampal ACh release increases from baseline during active exploration of the test environment and an empty test board, but a specific further increase is seen during the recognition memory task performance. This novel experimental model offers a good tool to study the impact of selective lesions or pharmacological manipulation simultaneously on neurotransmitter levels and memory task performance.

Recollection and familiarity through the looking glass: when old does not mirror new.

The authors use the qualitative differences logic to demonstrate that 2 separate memory influences underlie performance in recognition memory tasks, familiarity and recollection. The experiments focus on the mirror effect, the finding that more memorable stimulus classes produce higher hit rates but lower false-alarm rates than less memorable stimulus classes. The authors demonstrate across a number of experiments that manipulations assumed to decrease recollection eliminate or even reverse the hit-rate portion of the mirror effect while leaving the false-alarm portion intact. This occurs whether the critical distinction between conditions is created during the test phase or manipulated during the study phase. Thus, when recollection is present, it dominates familiarity so that the hit-rate portion of the mirror effect primarily reflects recollection; when recollection is largely absent, the opposite pattern associated with the familiarity process emerges.

Neuronal activity related to visual recognition memory: long-term memory and the encoding of recency and familiarity information in the primate anterior and medial inferior temporal and rhinal cortex.

Recordings of the activity of 2705 single neurones were made in entorhinal and perirhinal cortex, area TG of the temporal lobe, and the inferior temporal cortex both during monkeys' performance of a serial recognition memory task using complex pictures and when monkeys were shown objects. Responses of 120 (9.7%) of the visually responsive neurons recorded were significantly smaller to the second than to the first presentations of unfamiliar stimuli. The incidence of such responses was highest in perirhinal cortex plus areas TE1 and TE2 of the temporal lobe, intermediate in lateral entorhinal cortex and areas TE3 and TG, and lowest in other parts of entorhinal and inferior temporal cortex. Response decrements were maintained across 20 or more intervening presentations of other stimuli for the majority of the neurones tested. Responses of 43 (14.4%) of the visually responsive neurones tested were significantly greater to unfamiliar than to highly familiar stimuli. Such differential responses were found only in lateral entorhinal and perirhinal cortex plus areas TG, TE1, TE2 and TE3. For 6 neurones the response difference was significant even when the familiar stimuli had not been seen for more than 24 h: such neurones demonstrate access to information stored in long-term memory for more than 24 h. Seven familiarity neurones signalled information concerning the relative familiarity of stimuli but not information concerning how recently they were last seen; 58 recency neurones signalled information concerning the recency of presentation of stimuli, but not their relative familiarity. Thus certain neurones demonstrate the separable encoding of recency and familiarity information. Neurones signalling information of use for recognition memory are found in cortex close to the rhinal sulcus where lesions result in major deficits in the performance of recognition memory tasks. The conjunction of these findings provides strong evidence for the importance of these neurones and this cortex for processes (recency and familiarity discrimination) necessary for recognition and working memory. The possible relation of the neuronal responses to priming memory is also discussed.

Chapter 33 Neuronal signals of importance to the performance of visual recognition memory tasks: evidence from recordings of single neurones in the medial thalamus of primates

Publisher Summary The chapter discusses the activity of single neurones recorded within the medial thalamus of monkeys during their performance of recognition memory tasks with the objective of discovering what information relating to recognition memory neurones of the MD and MID nuclei might signal. A further objective is to compare the responses of such thalamic neurones with those found in the medial temporal lobes. The experiments performed demonstrated the presence of neuronal activity that encodes information about the previous occurrence of stimuli in the magnocellular division of the mediodorsal nucleus and the caudal part of the paraventricular midline nucleus of the medial thalamus. The conjunction of these results with the findings of lesion studies demonstrates the importance of these parts of the medial thalamus for processes necessary for recognition memory. The findings for the medial thalamus are considered in relation to those in other areas, particularly the medial temporal lobe and basal forebrain, areas that lesion experiments indicate is necessary for performance of recognition memory tasks. It is concluded that these interconnected areas form part of the system allowing the discrimination of the recency of occurrence and familiarity of stimuli.

The effects of attention-directing training on recognition memory task performance of three-year-old children

Thirty-eight 3-year-old children served as subjects in an investigation of recognition memory in which schematic faces differing only in the orientation of the eyes were employed as stimuli. A pretest was administered to all children, after which the two experimental groups received training in either attention to the distinctive feature of the training stimuli (also schematic faces) by means of a matching task, or in labeling the faces according to how they looked (sleepy, happy, sad, mad) and in using the labels to perform a matching task. After the training session all children were given a posttest on recognition memory of the faces. The verbally trained group obtained significantly higher scores on the posttest than either the feature or control groups. These results indicate that although the children were able to discriminate the faces, evidenced in their ease of performance on the training tasks, they were not able to use this knowledge unless given training in attaching labels to the stimuli, which enabled them to store the information for later use. Results are discussed in light of Gibson's (1969) theory of the developmental interrelations of cognitive processes.

Pictorial memory processes

When pictures are compared to words as stimuli in experimental learning tasks, significant differences are usually found. Pictures result in better performance in recognition memory tasks (e.g., Snodgrass, Volvovitz, & Walfish, 1972; Standing, 1973), in free recall tasks (e.g., Dallett & Wilcox, 1968; Sampson, 1970), and as stimulus items in paired associate learning tasks (e.g., Kopstein & Roshal, 1954; Jenkins, 1968). On the other hand, under some conditions involving sequential memory, words result in better performance (e.g., Paivio & Csapo, 1969, 1971). Such research has led to conflicting speculations concerning the memory mechanisms by which pictures and words are processed. One general approach has been to maintain that the processing of pictorial stimuli can be satisfactorily accounted for by the same memory mechanisms that are used to describe the processing of verbal information. A second approach has been to emphasize the differences in processing words and pictures and to argue for the utility of memory