AbstractIn the present study, a model for analyzing the performance of laser-based satellite uplinks that account for beam wander and atmospheric turbulence is presented. The developed scintillation index model is a continuation of the recent works considering the effects of non-Kolmogorov turbulence on the propagation of Gaussian beams across turbulent media. We specifically concentrate on the specific regime under the tilt-corrected beam wander. The on-axis scintillation index is developed assuming an isotropic non-Kolmogorov spectrum model where the power law exponent (PLE) effective value, $$\alpha$$ α , is taken to be 3 < $$\alpha$$ α < 4. Within that regime, effective irradiance models for tilt-corrected beam wander are presented, using the Gamma and Gamma-Gamma distributions. Closed-form expressions of the average bit error rate (BER) are derived to evaluate the performance of the optical communication system considering coherent detection of differential phase shift keying. The obtained numerical results show the impact of the Gaussian beam radius at the transmitter, the PLE effective value, and the zenith angle on the on-axis scintillation index and the average BER of the system under consideration. Due to beam wander, the link performance in terms of scintillation index and average BER depends on the beam radius at the transmitter. With tilt-corrected beam wander the link performance becomes best at an intermediate value of beam radius. With the non-Kolmogorov turbulent medium model, the PLE effective value has a major effect on the beam radius with the best performance. The obtained results guide the choice of the optimum beam radius for best performance for each PLE effective value.