Function In Elderly People Research Articles

Oral Frailty as a Risk Factor for Malnutrition and Sarcopenia in Patients on Hemodialysis: A Prospective Cohort Study.

Oral frailty is a concept that encompasses various aspects of impaired oral function in elderly people, leading to reduced food intake and less dietary diversity, which can result in sarcopenia and physical frailty. However, there have been no studies on the relationship between oral frailty and malnutrition, sarcopenia, and physical frailty in patients on hemodialysis (HD). This prospective observational cohort study assessed the oral status of patients on HD. The patients were divided into an oral frailty group and non-oral frailty group using the Oral Frailty Index-8. Malnutrition was assessed using the Geriatric Nutritional Risk Index (GNRI), the Nutritional Risk Index for Japanese Hemodialysis Patients (NRI-JH), and the Short-Form Mini-Nutritional Assessment (MNA-SF). Sarcopenia was assessed using the Asian Working Group for Sarcopenia 2019's criteria. Physical frailty was assessed using the Japanese version of the Cardiovascular Health Study criteria. One year later, the changes in nutritional status, sarcopenia, and physical frailty risk categories were compared between the oral frailty and non-oral frailty groups. The study enrolled 201 patients (non-oral frailty group, 123; oral frailty group, 78). After 1 year, the oral frailty group had a significantly higher proportion of patients with worsening nutrition status (GNRI, p = 0.0011; NRI-JH, p = 0.0019; MNA-SF, p < 0.001) and sarcopenia (p = 0.0024). There was no significant between-group difference in the proportion of patients in a worse risk category for physical frailty after 1 year. Oral frailty predicts future malnutrition and the progression of sarcopenia in HD patients. In particular, our results strongly suggested that oral frailty was a strong determinant of worsening malnutrition and sarcopenia in HD patients aged ≥65 years.

Factors Associated With Cognitive And Functional Performance In Elderly People In Cali, Colombia. A Multifactorial Approach.

Factors Associated With Cognitive And Functional Performance In Elderly People In Cali, Colombia. A Multifactorial Approach.

Slow walking speed and health-related exit from employment among older workers over 5 years of follow-up: evidence from the Health and Employment After Fifty (HEAF) cohort study

IntroductionWith demographic changes, there is increasing demand for individuals and governments to lengthen working lives. Jobs that are very physically demanding are likely to be more difficult to sustain at...

Determining the relationship between oral health and physical function in elderly people.

Poor oral conditions in the elderly may have numerous effects on general health, including physical fitness and performance. This study aimed to determine the relationship between oral health and physical function in elderly people. Physical function and oral health parameters were compared using parametric comparison tests and Pearson correlation analyses. In addition, principal components analysis, hierarchical clustering and multidimensional scaling analysis clustered the patients' physical and oral health scores. The relationship between the groups was also determined using decision tree analysis. A total of 112 elderly patients participated in the study. Grip strength (GS) was higher in patients with high chewing ability, and Timed Up and Go (TUG) scores were lower in the high oral health group (p < .05). GS was correlated with Decay, Missing, and Filled Teeth Index (DMFT) and the number of remaining and functional teeth (p < .05). According to principal component analysis, it was seen that there were three components (oral, functional and quality of life (QoL) parameters), and the features that were related to each other were gathered together. TUG and GS showed the highest relative importance among physical function criteria in the classification based on chewing ability. They were GS and physical activity for oral health-related QoL. In the elderly, higher physical function parameters, especially GS may be an indicator of a better oral health and oral health-related QoL. Preventive physical rehabilitation practices, in addition to oral treatments, may be effective in improving oral health in the elderly.

The effect of Baduanjin exercise on cognitive function in elderly people: A systematic review based on near-infrared spectroscopy technology

To systematically evaluate the application of near-infrared spectroscopy technology in the study of the effect of Baduanjin exercise on cognitive function in elderly people. Relevant literature was retrieved from PubMed, Web of Science core database, ScienceDirect, Wanfang, VIP, and CNKI from 2014 to June 2023, and relevant data were extracted. A total of 1 valid literature was obtained, published in 2022, sourced from the medical journal FRONTIERS IN PUBLIC HEALTH, with an impact factor of 6.46. This journal belongs to JCR Q1 area, and the SCI basic version of the Chinese Academy of Sciences is in the Q3 area of medicine. The inclusion criteria for the subjects of this study were age 60 years, experience of Baduanjin exercise for 3 years, and MMSE score 24 points. This study, based on functional near-infrared spectroscopy technology, explores the effects of Baduanjin imagery and Baduanjin exercise on cognitive function in elderly people. Baduanjin exercise can increase brain connectivity, improve brain structural connections, and enhance brain function in elderly people. These three factors are also the main reasons for Baduanjin exercise to promote the improvement of cognitive function, including increasing brain gray matter volume, brain functional area connections, etc. Baduanjin exercise can improve specific cognitive functions by increasing gray matter volume. Baduanjin exercise can regulate the functional connections of the cognitive control network in elderly people and improve their memory.

707-P: Advanced Glycation End Products and Executive Functions in Elderly People with Type 2 Diabetes

707-P: Advanced Glycation End Products and Executive Functions in Elderly People with Type 2 Diabetes

Effectiveness of a Sustainable Training Program Combining Supervised Outdoor Exercise with Telecoaching on Physical Performance in Elderly People

The decrease in functional abilities can negatively influence quality of life and autonomy in elderly people, and physical exercise plays a crucial role regardless of the type. Among the latter, also due to the COVID-19 pandemic, outdoor exercise and telecoaching are settings that have been widely implemented. Hence, the aim of this study was to investigate the effectiveness of a sustainable training program combining supervised outdoor exercise with telecoaching on physical performance in elderly people. A total of 60 participants were recruited and divided into two groups: a trained group (TG) and an untrained group (UG), based on their participation in an 8-week sustainable training program consisted of five sessions/week, which included two sessions/week of supervised outdoor exercise and three sessions/week of telecoaching. Participants were evaluated before and at the end of the training program using the handgrip test, Timed Up and Go (TUG) test, short physical performance battery (SPPB), and Tinetti scale. In the TG, we found a significant improvement in the following tests: right handgrip (p &lt; 0.001); left handgrip (p &lt; 0.001); TUG (p &lt; 0.001); SPPB (p = 0.01); and Tinetti scale (p = 0.006). A detailed analysis of the SPPB and Tinetti scale showed the lack of significant changes in walking ability: gait speed (p &gt; 0.05) and walking parameters in the Tinetti scale (p &gt; 0.05). Based on our results, we suggest that a sustainable training program combining supervised outdoor exercise with telecoaching could be effective in the elderly population for improving balance capacity and strength.

Intervensi Terapi Musik dapat Meningkatkan Fungsi Kognitif pada Lansia

This study aims to identify the effect of music therapy interventions on cognitive function in elderly people in nursing homes. The method used in this research was a systematic review using a systematic search through the ProQuest, Clinical Key Nursing, PubMed, Sage journal, and Scopus databases with articles that met the inclusion criteria with publications between 2014 and 2023, as well as an article search technique using the PRISMA scheme stages. The results of this study show that the search results identified ten articles in which various types of music therapy interventions and durations of interventions stated that music therapy had a positive effect on the cognitive function of the elderly. The conclusion obtained is that music therapy interventions can be effective interventions to improve cognitive function in the elderly.

Role of alanine aminotransferase in the effects of urinary caffeine concentration and its primary metabolite concentration on cognitive function in older adults: Bayesian Kernel Machine regression analysis and mediation analysis.

This study aimed to explore the role of alanine aminotransferase (ALT) in the effects of urinary caffeine and its primary metabolites on cognitive function in elderly people. In this investigation, we meticulously curated a cohort from the 2011-2014 National Health and Nutrition Examination Survey (NHANES) database. Animal fluency emerged as the pivotal metric for assessing cognitive function within our study population. In order to navigate the intricacies of mixture analysis and circumvent potential complexities, we harnessed the power of Bayesian kernel machine regression (BKMR) models. This method allowed us to dissect the nuanced impacts of caffeine and its primary urinary metabolites on cognitive function. While accounting for caffeine and its metabolites, we analyzed the relationship between ALT and cognitive function through non-linear dynamics. Lastly, employing structural equation modeling, we probed the intriguing question of whether ALT mediates the influence of 3,7-dimethylxanthine on cognitive function. This comprehensive approach has unveiled a deeper understanding of the multifaceted interplay among these variables, offering invaluable insights into the determinants of cognitive function within our cohort. After meticulous adjustment for various covariates, our linear regression analysis unveiled a noteworthy finding: 3,7-dimethylxanthine demonstrated a significant positive correlation with cognitive function (p < 0.05). Importantly, within the BKMR model employed, 3,7-dimethylxanthine emerged as the most influential factor within the compound, with posterior inclusion probabilities of 0.995 and 0.939. Furthermore, our single-exposure effect model confirmed its presence at the 25th, 50th, and 75th percentile concentrations of other components within the compound. Interestingly, bivariate concentration curves indicated no interaction within the compound, underscoring the prominent impact of 3,7-dimethylxanthine on cognitive function. Subsequently, through a test of Restricted Cubic Splines (RCS), we revealed a non-linear relationship between ALT and cognitive function at the 10th, 50th, and 90th percentiles (p < 0.05), indicating a heightened risk of diminished cognitive function in the low ALT group. Employing structural equation modeling, we meticulously examined the mediating role of ALT in relation to 3,7-dimethylxanthine and cognitive function. However, our study results did not yield significant evidence of a mediating effect. This comprehensive analysis elucidates the intricate interplay between these variables, unveiling the subtle mechanisms governing cognitive function. In this study, a noteworthy positive correlation was observed between 3,7-dimethylxanthine and cognitive function. Additionally, a non-linear relationship was identified between ALT and cognitive function, with lower levels of ALT associated with a decline in cognitive function. The RCS trend suggested that higher levels of ALT may similarly lead to diminished cognitive performance. However, in our pursuit to ascertain potential mediation, we regrettably found no significant evidence supporting mediation among these factors involving ALT. This underscores the need for more comprehensive investigations and expanded clinical explorations into the intricate associations among these three pivotal elements.

Air particulate pollution exposure associated with impaired cognition via microbiota gut-brain axis: an evidence from rural elderly female in northwest China.

This study aimed to reveal harm of exposure to indoor air pollution to cognitive function through "gut-brain-axis" among rural elderly residents. There were 120 participants recruited in rural villages of northwest China from December 2021 to February 2022. The cognitive level was assessed by eight-item ascertain dementia (AD) questionnaire, and indoor air pollution exposure was measured by air quality sensor. Inflammatory cytokines and oxidative stress-related index were detected in blood serum. Fecal samples were collected for gut microbiota analysis. The 120 participants were divided into impaired cognition (AD8) (81/67.5%) and cognition normal (NG) (39/32.5%). And there had more female in AD8 (FAD) (55/67.9%) than NG (FNG) (18/46.2%) (P = 0.003). Exposure of air pollution in FAD was higher than FNG (PM1, PM2.5, PM10, P < 0.001; NO2, P < 0.001; CO, P = 0.014; O3, P = 0.002). The risk of cognitive impairment increases 6.8%, 3.6%, 2.6%, 11%, and 2.4% in female for every 1 μg/m3 increased in exposure of PM1, PM2.5, PM10, NO2, and O3, separately. And GSH-Px and T-SOD in FAD were significantly lower than the FNG group (P = 0.011, P = 0.019). Gut microbiota in FAD is disordered with lower richness and diversity. Relative abundance of core bacteria Faecalibacterium (top 1 genus) in FAD was reduced (13.65% vs 19.81%, P = 0.0235), while Escherichia_Shigella and Akkermansia was increased. Correlation analysis showed Faecalibacterium was negatively correlated with age, and exposure of O3, PM1, PM2.5, and PM10; Akkermansia and Monoglobus were positively correlated with exposure of PM1, PM2.5 and PM10; Escherichia_Shigella was significantly positively correlated with NO2. Indoor air pollution exposure impaired cognitive function in elderly people, especially female, which may cause systemic inflammation, dysbiosis of the gut microbiota, and ultimately leading to early cognitive impairment through the gut-brain axis.

PHYSICAL ACTIVITY ASSOCIATED TO LOWER PREVALENCE OFDEMENTIA IN BRAZILIAN OLDER ADULTS

AbstractBackgroundEvidences indicate that physically active older individuals maintain healthy functioning longer than do sedentary peers. Some lifestyle could impact the risk of dementia including Alzheimer’s. In spite of this, the effect of physical activity on the relationship between age and the risk of dementia is unknown. This is a two‐phase study that aims to investigate the association of physical exercise and age with the prevalence of dementia in community older adults, from Ribeirao Preto city, state of Sao Paulo, Brazil.MethodCross‐sectional study of a randomized community‐based sample of 928 elderly subjects aged 60 years or older was performed. Standardized instruments for screening dementia and a socio‐economic questionnaire were applied to the subjects at home in phase I. The dementia diagnose was made at hospital in phase II, according to DSM‐V criteria.ResultOveral Dementia was 6.0%. Alzheimer’s disease was the most frequent dementia (2.8%), followed by Vascular dementia (1.3%), and Mixed dementia (1.1%). Initial multivariate analysis showed sociodemographic factors associated to dementia. After adjusting for all the variables, multivariate analysis showed an association with age group ≥80 (OR = 6.7; p&lt;0.001); household chores (OR = 2.7; p = 0.004); no employment (OR = 4.3; p&lt;0.001); and stroke (OR = 4.5; p = 0.001). There was no association with gender, socioeconomic class, educational level, and alcohol use. Secondary analysis showed an inverse relationship between physical activity and age (OR = 0.4; p&lt;0.001). After deliberately exclude age, the final model showed a significant association between higher rates of dementia and lack of physical activity (OR = 2.0; p = 0.024).ConclusionAccording to previous studies, in our sample, lack of exercise was associated with two fold higher risk of dementia, only after exclude age of the analysis. This result could be due to decreasing level of physical activity found in the oldest subjects. We suggest that relatively simple lifestyle changes such as increasing the practice of exercise could enhance cognitive performance in elderly people. Future investigations are needed to clarify the real impact of physical activity on the relationship between dementia and age.

Evaluation of the rehabilitation potential of cochlear implantation on cognitive function in elderly people

Introduction. In the world there is an increase in the proportion of elder people in the demographic group of society. The problems of treatment and diagnosis of diseases associated with age due to this are considered more significant in clinical practice. Among of the most common age-related diseases: cognitive impairment, hearing loss and depression. Researchers have found that hearing loss is the most significant modifiable risk factor for cognitive impairment. Also, hearing impairment, according to several experts, is the cause of depression. Cochlear implantation is one of the main methods of rehabilitation in case of profound impairment of auditory function in elder people.Aim. Evaluate the rehabilitation potential of cochlear implantation on cognitive function in elder people.Materials and methods. A prospective study, were selected 35 patients (15 men, 20 women), candidates for cochlear implantation. Average age at the start of the study was 65 ± 9 years. Cognitive function was assessed using the RBANS-H, HI-MoCA, sound quality assessment using the HISQUI19, depression and anxiety level assessment using the HADS. Studies were conducted before surgery, 6 and 12 months after the activation of the cochlear implant.Results. There was an increase in cognitive function, assessed by the RBANS and HI-MoCA. In addition, the patients showed a decrease in the levels of depression and anxiety, assessed by the HADS test.Conclusions. Cochlear implantation, as a method of rehabilitation of deep hearing impairment in elder people, has shown high efficiency on cognitive function, and decrease of depression and anxiety in the postoperative period.

Clinical Features of Subjective Cognitive Decline in The Early Stages of Alzheimer’s Disease

Subclinical stage of the disease precedes the clinical stage of moderate cognitive decline in Alzheimer's disease (AD). Subjective cognitive decline (SCD) — a condition in which the level of cognitive function habitual for the subject gradually begins to decrease. In 2021, researchers from the National Institute on Aging and the Alzheimer's Association (NIA-AA) clinical criteria for the diagnosis of SCD have been proposed, as well as features that increase the probability of preclinical stage AD in patients with moderate cognitive impairment have been identified. Patients should be offered a complex of examinations — questionnaires regarding the impact of memory impairment on current cognitive activity (forgetfulness, searching for things, difficulty finding words, etc.), testable self-report of cognitive dynamics, neuropsychological testing and diagnosis of pathopsychological changes such as depression and anxiety. It would appear that counselling in the form of interviews and/or testing of persons able to provide relevant information about the patient should be included in the examination of patients with complaints of memory disorders, regardless of their degree of severity. It may be necessary to conduct a survey on the patient’s daily activity, ability to self-service (score, orientation, planning, control and so on), as well as to obtain information about any memory-related changes that have become visible to others, because it is the data from the partner/relative that increase the predictive value of the diagnostic. The modern approach to the study of cognitive functions in elderly people without dementia in the long-term is certainly able to help identify people with a high risk of developing AD.

Penerapan Aplikasi Mefuko (MMSE Untuk Fungsi Kognitif) Pada Lansia Dengan Demensia

An elderly person is someone who has reached the age of 60 years and over. One of the health problems that often occurs in the elderly is a decline in memory, learning and cognitive abilities in the elderly which causes them to have difficulty interacting and being difficult to understand. Conditions that affect cognitive abilities in the elderly are called dementia. Dementia is a chronic and progressive decline in memory and thinking function, causing disruption of functional activities. Nursing interventions that can be given to the elderly to improve cognitive function in the occurrence of dementia include brain gymnastics. The case study design used is descriptive research. The method used to collect data is using the Android-based MMSE (Mini Mental State Examination), namely MEFuKo (MMSE for Cognitive Function) to determine the level of dementia in the elderly. Brain exercise therapy (brain gym) is carried out for 7 consecutive days, 1 meeting per day with a duration of 15 minutes. Subject I's MMSE score before brain exercise therapy was 16 (presence of definite cognitive impairment) increased to 19 (presence of probable cognitive impairment) and there was an increase of 3 in total MMSE scores. The MMSE score in subject II before brain exercise therapy was 19 (possible cognitive impairment), after therapy the MMSE score became 23 (probable cognitive impairment) and there was an increase of 4 in total MMSE scores. The more activities you do, the less likely it is that seniors will experience a decline in cognitive function. The conclusion is that there was an increase in cognitive function in the two case study subjects which illustrate the application of brain gym therapy to cognitive function in elderly people with dementia. Brain exercise therapy is recommended to improve working memory function which can improve the quality of life of the elderly.

Exercise and Cognition in Elderly

In developed countries, the population is aging. The aging process brings forth a slew of physical and mental changes. There has been a progressive deterioration in the degree of cognitive processes closely tied to the aging process, which is most commonly associated with age-related disorders such as dementia, throughout time. Physical activity and exercise have been identified as a method for promoting older health, as well as encouraging the maintenance of functional ability and acting in the prevention and control of a variety of diseases. The benefits of physical activity in the preservation or even improvement of cognitive performance in both the old without cognitive impairment and the elderly with some degree of cognitive impairment or dementia have piqued researchers’ interest in recent years. The goal of this study was to examine the effects of various types of physical activity and exercise on cognitive function in elderly people with and without prior cognitive impairment, to identify potential mechanisms underlying these effects, and to make exercise prescription recommendations to improve cognitive performance.

System Development and Evaluation of Human–Computer Interaction Approach for Assessing Functional Impairment for People with Mild Cognitive Impairment: A Pilot Study

Non-pharmacological treatments have gained significant attention in the field of cognitive impairment. Among them, human–computer interaction-based (HCI) methods have emerged as a promising approach due to their broad applicability and convenience in assessing symptoms associated with this progressively debilitating condition. However, existing rehabilitation training systems for cognitive impairment lack effective assessment methods to meet the diverse rehabilitation needs of users. In this article, we surveyed existing HCI-based cognitive rehabilitation training systems and analyzed their advantages and shortcomings. Drawing from the insights gained from these systems, we propose a novel Leap Motion-based building block training system that incorporates system software capable of generating highly realistic virtual scenes, with the added capability of user behavior detection using Kinect. We conducted user testing of this new system, comparing the performance of a representative cohort with mild cognitive impairment (MCI) (n = 9) to that of disease-free participants (n = 10). Additionally, we conducted ergonomic experiments to assess the system’s performance in elderly people. The experimental results revealed significant differences between the MCI cohort and the control cohort. Specifically, the MCI cohort exhibited a reduced range of motion and longer task completion times compared to the control cohort. These findings have the potential to contribute to the differentiation of cognitive levels. In conclusion, our analysis of existing cognitive rehabilitation training systems provides valuable insights for researchers working on the development of future innovative cognitive rehabilitation training systems and enriches the non-pharmacological treatment models for cognitive impairment. Furthermore, the observed relationship between behavioral data, task completion times, and cognitive levels in older adults offers useful insights for the design of HCI-based approaches for diagnosing and assessing the treatment of MCI.

Enhancing Cognition in Older Adults with Mild Cognitive Impairment through High-Intensity Functional Training: A Single-Blind Randomized Controlled Trial.

Physical exercise is a very promising non-pharmacological approach to prevent or reduce the cognitive decline that occurs in people aged 60 years or older. The objective of this study was to determine the effect of a high-intensity intervallic functional training (HIFT) program on cognitive functions in an elderly Colombian population with mild cognitive impairment. A controlled clinical trial was developed with a sample of 132 men and women aged >65 years, linked to geriatric care institutions, which were systematically blind randomized. The intervention group (IG) received a 3-month HIFT program (n = 64) and the control group (CG) (n = 68) received general physical activity recommendations and practiced manual activities. The outcome variables addressed cognition (MoCA), attention (TMTA), executive functions (TMTB), verbal fluency (VFAT test), processing speed (Digit Symbol Substitution Test-DSST), selective attention and concentration (d2 test). After the analysis, improvement was found in the IG with significant differences with respect to the CG in the level of cognitive impairment (MoCA), attention (TMTA), verbal fluency and concentration (p < 0.001). Executive functions (TMTB) showed differences in both groups, being slightly higher in the IG (p = 0.037). However, no statistically significant results were found for selective attention (p = 0.55) or processing speed (p = 0.24). The multiple analysis of covariance (MANCOVA) showed the influence of the education level on all cognition assessments (p = 0.026); when adjusting for sociodemographic variables, the influence of the intervention remained significant (p < 0.001). This study empirically validates that the implementation of a HIFT program has a positive effect on cognitive functions in elderly people with mild cognitive impairment. Therefore, professionals specialized in the care of this population could consider including functional training programs as an essential part of their therapeutic approaches. The distinctive features of this program, such as its emphasis on functional training and high intensity, appear to be relevant for stimulating cognitive health in the geriatric population.

The effect of grape seed procyanidins extract on cognitive function in elderly people with mild cognitive impairment: A randomized, double-blind, placebo-controlled clinical trial

BackgroundProcyanidins have antioxidative properties that may protect against age-related brain oxidative stress. Previous studies indicated that procyanidin-rich foods could improve cognitive function and prevent neurodegenerative diseases. This study hypothesized that grape seed procyanidins extract (GSPE) would have a favorable effect on cognitive function in elderly people with mild cognitive impairment (MCI). MethodsA community-based, randomized, double-blind, placebo-controlled trial was conducted. Participants aged 60 years or older with MCI were randomly assigned into the GSPE group (n = 35, 320 mg/d) or placebo group (n = 36), and received capsules for 6 months. Cognitive function was assessed using the Montreal Cognitive Assessment Scale (MoCA). The change in MoCA scores between groups were tested by the time ✕ treatment interaction in mixed-design ANOVA. ResultsAfter 6 months of intervention, the MoCA score was higher than the baseline both in the intervention group and placebo control group, while the there was no significant difference for mean change in MoCA score from baseline between the intervention group and the placebo group (2.35 ± 3.20 vs. 1.28 ± 2.93, P = 0.192). ConclusionsPresent study showed that 6-month supplementation with GSPE did not significantly improve cognitive function in subjects with MCI. Further investigations regarding the longer-term intervention effect of procyanidins extract on mild or moderate cognitive disorders are needed.

Effects of multimodal physical activity program in the cognive functions and functional fitness test in elderly with and without Alzheimer Disease

AbstractBackgroundAlzheimer’s Disease (AD) is the most prevalent disease among all dementias, and is characterized by progressive deficits in cognitive function and activities of daily living.The aim of this study was compare effects of multimodal physical activity program in functional capacity, memory, and attention in elderly with and without AD.MethodEighteen elderly with AD were ramdomized into the control (AD‐C) or multimodal physical activity program (AD‐T) groups. Also twenty without AD were divided in the control (NAD‐C) or physical activity program (NAD‐T) groups. All participants performed the international physical activity questionnaire, neuropsicological evaluation using Mini Mental State Examination, Syndrom Kurztest (SKT), clinical dementia rating. The functional fitness test was evaluated by the muscular resistance (30‐second chair stand and arm curl), aerobic capacity (2‐minute step in the place), lower and upper body flexbility (chair sit‐and‐reach, and back scratch tests) and agility/dynamic balance (8‐foot up and go). The shoulder and ankle amplitude were measured using a Fleximeter. The multimodal physical activity program included warm up, aerobic exercises, strength, flexibility, and cool down for 3 months, twice a week, with 75 min each session for NAD‐T and AD‐T groups.ResultThe physical activity program significantly increased the leisure‐time physical activity level, upper body muscular strength, aerobic capacity, upper and lower body flexibility, shoulder and ankle extension range in the NAD‐T and AD‐T (P&lt;0.05). Also increased agility/dinamic balance compared to the AD‐C group (P&lt;0.05). Concerning the cognition, the multimodal training improved SKT‐memory in both groups NAD‐T and AD‐T (P&lt;0.05). SKT‐atention improved in the NAD‐T group (P&lt;0.05).ConclusionThe multimodal physical activity program was effective in increasing the level of leisure‐time physical activity, aerobic capacity, muscle strength, lower limb flexibility, shoulder extension, and memory, independent of the AD. Additionaly, the program attenuated the decline in agility/dinamic balance compared to the AD‐C group. Attentional function improved in the NAD‐T group. These benefits may contribute to a better performance in activities of daily living, reduction of falls and attenuation of the decline of cognitive functions in elderly people with and without AD.

FUNCTIONAL STATE OF THE AUTONOMIC NERVOUS SYSTEM IN ELDERLY PERSONS WITH POSTURAL INSTABILITY

Background. Preservation of postural balance allows the elderly people to remain mobile and lead an active lifestyle. There is evidence of the contribution of the ANS to the coordination of postural responses and the maintenance of postural stability in young adults. However, similar data for the elderly is not enough and this issue requires further study.&#x0D; Purpose. To reveal the peculiarities of ANS functioning in elderly people with postural instability.&#x0D; Materials and methods. In 120 women aged 60-74 years, a survey, anthropometry, assessment of the dynamic component of postural balance by stabilometry and heart rate variability by cardiointervalography were performed. The study group included elderly people with postural instability (60 people), the control group included 60 women who did not report such facts. Data analysis was performed using “SPSS 27.0”.&#x0D; Results. The state of postural balance in the study group was characterized by a decrease in walking speed (p = 0.008) and a rise index when moving from the right leg (p = 0.016), an increase in the speed of oscillations of the center of body mass in the lifting phase (p = 0.047), oscillations of the center of gravity during rotation when moving on the left (p=&lt;0.001) and right (p=0.003) legs, turn time when moving on the left (p=0.44) and right (p=0.36) legs.&#x0D; Conclusion. The results demonstrate a decrease in the quality and efficiency of postural balance regulation in elderly women with postural instability. We did not reveal any significant differences in the indicators characterizing the activity of different parts of the ANS depending on the facts of postural instability.