Perception Of Musculoskeletal Pain Research Articles

Impact of sensory neuropeptide deficiency on behavioral patterns and gait in a murine surgical osteoarthritis model.

Substance P (SP) and a calcitonin-related gene alpha (αCGRP-/-) are implicated in musculoskeletal pain perception and were shown to have different effects on the pathogenesis of osteoarthritis (OA). However, it has not been investigated, whether deficiency for SP or αCGRP impacts pain-related behavior and well-being as well as gait during development of experimental OA. We induced OA in the right knee of wild-type (WT) mice and mice either deficient for SP (tachykinin 1, Tac-1) or αCGRP (male, n = 8 per genotype) by destabilizing the medial meniscus (DMM). We monitored body weight and food and water intake as indicators of wellbeing, determined nest building and composite pain score, and performed CatWalk gait analysis over 12 weeks. Cartilage degeneration was determined by OARSI scoring. The 12-week post-DMM, cartilage degradation in the medial compartment was significantly reduced in Tac1-/- mice compared to the WT and to αCGRP-/- mice, coinciding with highest unloading of the operated limb in Tac1-/-. Behavioral and gait analysis revealed only minor differences between the genotypes. Paw print area was most prominently reduced in Tac1-/- over the observation period; at 12 weeks, we found a significant reduction in normalized print area in Tac1-/- compared to presurgery and to the WT at the same time-point. Calculated weight bearing was significantly reduced only in Tac1-/-. Overall, we observed minor impact of DMM on gait and behavior in the present study. The reduced cartilage damage in the absence of SP might be in part due to reduced loading, however, the mechanism is not clear yet.

Physical Demands of Walking Football in Patients With Cardiovascular Risk Factors and Diseases.

To compare the exercise intensity of walking football (WF) with walking (WA) and to describe specific movement characteristics of WF. Cross-sectional study. Sports facilities Saarland University, Germany. Eighteen patients with cardiovascular risk factors CVRFs and diseases (13 men and 5 women, age: 69 ± 10 years). Patients completed a WF match and WA session of 2 x 10 min each. Video analysis was used to characterize movements during WF. Rate of perceived exertion (RPE, Borg Scale 6-20), % maximum heart rate (HR max ), musculoskeletal pain on a visual analog scale (VAS, 1-100 mm) before and up to 72 hours after exercise, and movement patterns during WF. The mean RPE during WF (12.1 ± 2.7) and WA (11.9 ± 3.0) did not differ ( P = 0.63). The mean HR during WF (79 ± 12% of HR max ) was higher than during WA (71% ± 11%; P < 0.01). The HR variability coefficient of variation during WF (10.3% ± 5.8%) and WA (7.1 ± 5.5%) did not differ ( P = 0.13). There was no influence of exercise mode (WF vs WA) on musculoskeletal pain perception ( P = 0.96 for interaction). Injury-inciting activities such as lunges (median: 0.5 [interquartile range (IQR) 0-1.3]) and goal kicks (median: 4 [IQR: 1.8-5.3]) occurred rarely during WF. Walking football might represent an alternative to WA for health prevention programs in patients with CVRF and diseases as it is characterized by a manageable cardiocirculatory strain, moderate RPE, low pain induction, and a low number of injury-inciting activities.

Perception of musculoskeletal pain in the state of confinement: associated factors.

Objective:to describe the perception of musculoskeletal pain in the population and how the state of confinement (adopted as a measure to control contagion by COVID-19) has interfered with it, as well as identifying the sociodemographic, occupational, physical, and psychosocial factors involved.Method:an observational, cross-sectional and analytical study, with simple random probabilistic sampling, aimed at residents in Spain over 18 years old during the confinement period. An ad hoc survey was conducted, consisting in 59 items.Results:a total of 3,247 surveys were answered. Persistent musculoskeletal pain or significant episodes thereof increased 22.2% during confinement. The main location was the spine (49.5%). The related factors were decreased physical activity, increased seated position, and use of electronic devices. The psychological impact of confinement was also related to the perception of musculoskeletal pain.Conclusion:the state of confinement causes an increase in the perception of musculoskeletal pain. The identification of a particularly sensitive population profile, as well as that of the related factors, allows establishing multidisciplinary approaches in health promotion.

Serum dehydroepiandrosterone sulphate, psychosocial factors and musculoskeletal pain in workers.

The serum level of dehydroepiandrosterone sulphate (DHEA-S) has been suggested as a biological marker of stress. To assess the association between serum DHEA-S, psychosocial factors and musculoskeletal (MS) pain in university workers. The study population included voluntary workers at the scientific departments of the University of Trieste (Italy) who underwent periodical health surveillance from January 2011 to June 2012. DHEA-S level was analysed in serum. The assessment tools included the General Health Questionnaire (GHQ) and a modified Nordic musculoskeletal symptoms questionnaire. The relation between DHEA-S, individual characteristics, pain perception and psychological factors was assessed by means of multivariable linear regression analysis. There were 189 study participants. The study population was characterized by high reward and low effort. Pain perception in the neck, shoulder, upper limbs, upper back and lower back was reported by 42, 32, 19, 29 and 43% of people, respectively. In multivariable regression analysis, gender, age and pain perception in the shoulder and upper limbs were significantly related to serum DHEA-S. Effort and overcommitment were related to shoulder and neck pain but not to DHEA-S. The GHQ score was associated with pain perception in different body sites and inversely to DHEA-S but significance was lost in multivariable regression analysis. DHEA-S was associated with age, gender and perception of MS pain, while effort-reward imbalance dimensions and GHQ score failed to reach the statistical significance in multivariable regression analysis.

Quality of life, perception and knowledge of dentists on noise

ABSTRACT Purpose: to analyze the perception and knowledge of dentists on occupational noise, its prevention, and effects on their health and quality of life. Methods: a cross-sectional study carried out with 54 dentists of both genders. Two questionnaires were applied: one addressing issues of perception and knowledge on noise and its effects, and another on Quality of Life (SF 36). Results: the workplace noise was considered within medium intensity, and a health risk. Some professionals (59.2%) reported knowing noise prevention methods, although they do not use them. Complaints and the most frequently reported symptoms were irritability, difficulty in understanding speech and tinnitus. The perception of the Quality of Life was worse among men. There was association between pain and perception of noise intensity. Conclusion: noise was considered, regardless of gender, harmful to health and associated with perception of musculoskeletal pain. Symptoms and complaints caused by noise have been reported to negatively impact the professional activity of dentists, however, most of them do not adopt preventive measures.

PERCEPÇÃO DE DOR E ALTERAÇÕES MUSCULOESQUELÉTICAS EM ATLETAS DE BASQUETE NA PREPARAÇÃO PARA OS JOGOS UNIVERSITÁRIOS DE 2014

Objetivo: Avaliar a percepção de dor e alterações musculoesqueléticas em jogadores de basquete na preparação para o 62° jogos Universitários Brasileiros. Métodos: Foi realizado um estudo analítico de caráter retrospectivo com atletas de basquete, de ambos os sexos registrados no 62° jogos Universitários Brasileiros de 2014. Os atletas foram avaliados antes do início dos jogos, os atletas responderam perguntas sobre a percepção de dor musculoesquelética e ocorrência de alguma lesão durante a preparação para os jogos universitários. Resultados: Foi realizada estatística descritiva e inferencial utilizando o software SPSS versão 20.0.Foram entrevistados 296 jogadores de basquete distribuídos em 34 equipes, sendo 19 masculinas e 15 femininas. A idade média foi de 22,08 ± 3,62 anos e 170 (57,4%) foram do sexo masculino. Dos 296 atletas, 185 (62,5%) relataram sentir alguma dor e 213 (72%) relataram a presença de alguma lesão durante a preparação para a competição. 73 (39,5%) relataram sentir dor no joelho, seguido da coluna 45 (24,3%), 24(13%) membro superior, 18 (9,7%) tornozelo e pé. Quando comparada a amostra em relação ao sexo não houve diferença estatisticamente significativa em relação à idade, percepção de dor e regiões corporais afetadas. Já em relação à ocorrência de lesões na preparação, foi observada uma diferença estatisticamente significativa, com maior prevalência nas equipes do sexo masculino. Conclusão: Existe uma alta prevalência de dor e alterações musculoesqueléticas em atletas de basquete durante preparação para competição. Estudos que avaliem fatores associados a dor são necessários.

Potential Nociceptive Regulatory Effect of Probiotic Lactobacillus rhamnosus PB01 (DSM 14870) on Mechanical Sensitivity in Diet-Induced Obesity Model.

Treatments for obesity have been shown to reduce pain secondary to weight loss. Intestinal microbiota, as an endogenous factor, influences obesity and pain sensitivity but the effect of oral probiotic supplementation on musculoskeletal pain perception has not been studied systematically. The present study examined the effect of a single daily oral dose (1 × 109 CFU) of probiotics (Lactobacillus rhamnosus PB01, DSM14870) supplement on mechanical pain thresholds in behaving diet-induced obese (DIO) mice and their normal weight (NW) controls. The mice (N = 24, 6-week-old male) were randomly divided into four groups on either standard or high fat diet with and without probiotic supplementation. Both DIO and NW groups with probiotic supplementation maintained an insignificant weight gain while the control groups gained significant weight (P < 0.05). Similarly, both DIO and NW probiotics supplemented groups demonstrated a significantly (P < 0.05) lower sensitivity to mechanical stimulation compared to their corresponding control. The results of this study suggest a protective effect of probiotics on nociception circuits, which propose a direct result of the weight reduction or an indirect result of anti-inflammatory properties of the probiotics. Deciphering the exact underlying mechanism of the weight loss and lowering nociception effect of the probiotic applied in this study require further investigation.

Physical activity level and self-reported musculoskeletal pain perception among older males

BACKGROUND AND OBJECTIVES: In light of the social and economic impact caused by pain and the evidences of benefits provided by physical activity to individuals affected by this unpleasant sensation, this study aimed at evaluating the prevalence of selfreported musculoskeletal pain and at determining its association with the level of physical activity of males aged 40 years or above, dwellers of the urban zone of the city of Pelotas-RS. METHODS: This is an observational, cross-sectional and population-based study. The level of physical activity was measured by means of leisure and commuting sections of the International Physical Activities Questionnaire, being classified as insufficiently active those with scores below 150 minutes/week. To evaluate pain self-perception, a question of the Aging Male's Symptoms Scale was used. Those reporting moderate, severe and intense pain were classified as having pain. RESULTS: The prevalence of pain self-perception was 27.0% (CI95% 22.7 - 31.3) and was significantly associated to the level of physical activity (p<0.001). Males performing 150 minutes/ week or more of physical activity had 60% protection against pain report as compared to those not reaching this cutoff point, being that this result was maintained significant even after adjustment for confounding factors (p=0.02). CONCLUSION: This study has shown that reaching physical activity recommendations may be a protection against musculoskeletal pain perception among studied males.

Validity of self-reported physical work load in epidemiologic studies on musculoskeletal disorders.

This study assessed the validity of self-reported physical work load by questionnaire and logbook against task analysis and observation. It also investigated factors (job type and low-back or neck pain) affecting the self-assessment of physical work load and compared the assessments between the questionnaire and the logbook. A self-administered questionnaire including 10 questions (ordinal scales) on physical work load and musculoskeletal symptoms was filled out by 2756 men in the forest industry. From this population, 36 men were selected for task analysis and observation. Logbooks including 10 continuous variables were analyzed for 386 men. The Spearman rank correlation coefficients between the self-assessments and observations for the frequency of manual handling, duration of trunk flexion, neck rotation, hand above shoulder level, and squatting or kneeling ranged between 0.42 and 0.55. The correlation coefficients for the questionnaire items were higher in general, and the accuracy better, for those with no low-back pain than for those with pain. The duration of trunk flexion, neck flexion and hand above shoulder level was overestimated in the questionnaires and less so in the logbooks. Self-administered questionnaires may help to classify groups with heterogeneous occupational tasks according to some work-load factors. The accuracy of the assessments is not good for studying quantitative exposure-effect relationships, however. The logbook method might give more valid information. The perception of musculoskeletal pain may bias the self-assessment of work load.

The influence of psychological variables on the development and perception of musculoskeletal pain

The development and perception of pain is influenced by cognitive, affective and behavioural factors. It is dependent, for example, on selective attention and the filtering of potentially relevant messages. People who are vigilant and aware of bodily cues are more likely to respond by reporting pain. Labelling of the pain and its meaning to the individual also influences the pain response. Social modelling and social reinforcement help to explain individual differences in pain response. A person's future behaviour may be influenced by role models such as a parental figure. Pain responses may also be shaped by reinforcement from the current social environment. Finally, anxiety levels and mood state may be important moderators of pain responses.

The Perception of Musculoskeletal Pain and Incapacity for Work: Prevention and Early Treatment

Summary As normal life becomes easier from one generation to another, work and daily activities can be managed with fewer demands on the mobility and strength of the musculoskeletal system. But if the system is not regularly taxed by other means, symptoms from unaccustomed activity become more likely. Acute musculoskeletal pain, for the time being, makes a further reduction in the normal levels of exertion and movement; so increasing susceptibility to further trouble if it is not rapidly relieved. If rest is therapeutically prolonged, then rehabilitation becomes increasingly difficult. Immobilisation, moreover, is now recognised as a potential cause for osteoarthritis. The need for active management of acute musculoskeletal symptoms at the earliest possible stage is therefore clear. The difficulty lies in recognising where the need is greatest. Taking the population as a whole, capacity for work is reduced not only by current but also by previous symptoms. The experience of pain and the fear it engenders seem permanently to reduce the capacity for exertion and it is in such people that we may look for recurrent and chronic musculoskeletal symptoms. If fear of pain and the signs of pain-avoidance or illness-behaviour are ignored, omitted from the diagnosis and remain untreated, musculoskeletal morbidity may positively be encouraged instead of prevented.