Peptic ulcers, commonly referred to as PUDs or peptic ulcer disease, are very painful ulcers that typically occur in an acidic portion of the gastrointestinal tract. Either increased aggression or decreased mucosal resistance might upset the natural equilibrium, leading to ulceration. It could be brought on by stress, erratic eating patterns, frequent drug use, and other factors. Peptic ulcers develop when there is a breakdown in the mucosal barrier along with acidity and peptic activity in the stomach liquid. Mucosal resistance to damage is significantly disrupted by two major factors: Helicobacter pylori (H. pylori) infection and nonsteroidal anti-inflammatory medications (NSAIDs). However, in comparison to traditional remedies, these pharmaceuticals are more costly and probably have more negative effects. Pain relief, ulcer healing, and delaying the recurrence of the ulcer are the optimal goals of peptic ulcer disease treatment. The traditional, ethnobotanical, and ethnopharmaceutical uses of Indian herbal plants are unique. A few plants that may be utilised to treat or prevent peptic ulcers have been the subject of informational attempts in this review. Pain relief, ulcer healing, and recurrence prevention are the main objectives of peptic ulcer disease treatment.