This article discusses social determinants of health that influence quality of life (QOL) of older people in Botswana and suggests appropriate interventions. A cross-sectional study stratified by district was used to collect information on the elderly (N = 378). Data were collected from: demographics, individual factors (e.g., self-esteem), health-related factors (e.g., self-perceived health), clinical variables (e.g., social dysfunction), environmental assets (e.g., leisure) and the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF). The analyses showed that income earned, self-efficacy and self-esteem, access to health services, self-perceived health, and chronic disease condition were associated with QOL. Social dysfunction and environmental assets (leisure, secure and healthy physical environments) were also significantly associated with QOL The results confirm that QOL is compromised by specific key factors. Thus, eradicating poverty, provision of services and a comfortable environment, promoting positive emotions (e.g., self-efficacy), and changing perceptions about self-rated health and self-rated QOL may enhance QOL among older people. The study has implications for policy, practice and further research.
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