Lung cancer remains a leading cause of cancer-related mortality worldwide, significantly impacting public health. Concurrently, anxiety is a prevalent psychological disorder known to influence the development and progression of various cancers. This research paper aims to examine the combined influence of various factors, including demographic characteristics, environmental exposures, and physical conditioning data, on the incidence of lung cancer and anxiety. Given the binary nature of both lung cancer and anxiety outcomes, the analyses will first employ separate binary probit regression models to identify significant predictors for each condition independently. Then, joint modeling techniques will be implemented with dual purposes. First, by comparing the results of the individual and joint models, the reliability and robustness of the findings will be enhanced through cross-validation. Second, joint models will enable an investigation into potential endogeneity between lung cancer and anxiety. Addressing this endogeneity is crucial as it can potentially improve model robustness and provide deeper insights into the interrelationship between these two health outcomes. For the study purpose, the demographic factors considered include age and gender. Environmental factors encompass smoking history, alcohol consumption, and peer pressure. Physical conditioning data includes pre-existing health conditions such as yellow fingers, anxiety, chronic disease, fatigue, allergy, wheezing, coughing, shortness of breath, swallowing difficulty, and chest pain. By leveraging advanced statistical modeling techniques, this research seeks to uncover nuanced relationships and potential causal pathways that may exist between lung cancer and anxiety. The findings from this study will contribute to the existing body of knowledge by providing additional case study showing the relationship among a multitude of factors on lung cancer and anxiety, respectively. Also, the endogeneity checking among lung cancer and anxiety may enhance the efficiency of models done by others in the future. The research paper's analysis on lung cancer incidences reveals that age and wheezing are significant predictors. In examining anxiety levels, smoking emerged as a significant predictor, indicating a higher likelihood of anxiety among smokers. In addition, the joint probit models confirmed these findings, with age and wheezing significantly predicting lung cancer incidence, and smoking significantly predicting anxiety levels. No significant endogeneity was observed between lung cancer and anxiety, suggesting that these health outcomes are influenced by different sets of factors. These findings underscore the importance of considering demographic, environmental, and physical conditioning data in understanding and addressing lung cancer and anxiety, and checking their potential endogeneity
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