English Peer-reviewed Publications Research Articles

EXPLORING ARTS-BASED METHODS IN UNPAID CAREGIVING CONTEXTS: A SCOPING REVIEW

Introduction:Unpaid caregiving plays a crucial role in supporting older adults, requiring innovative approaches to understand and enhance caregivers' experiences. Research Objectives: As a response, this scoping review investigates the application of arts-based methods in understanding the caregiving experience, as well as the advantages and limitations of these methods in providing care to diverse populations. Methodology: Building on Arksey and O’Malley's framework, our methodology draws from the Joanna Briggs Institute approach. Eligibility criteria encompassed peer-reviewed publications in English from 2007 to 2022, focusing on unpaid caregivers, arts-based methods, and caregiving experiences. Six comprehensive databases were queried, with the initial searches yielding 761 articles. Full text screening of 66 papers resulted in 19 papers for inclusion in the scoping review. Results: Analysis of the literature revealed the multifaceted applications of arts-based methods in understanding and supporting unpaid caregivers. These encompassed a wide range of creative techniques, such as visual arts, photo elicitation, storytelling, and performance – which provided insights into the emotional, psychological, and social dimensions of caregiving. Findings highlighted the potential for arts-based methods to enhance caregiver well-being, foster self-reflection and self-care, and promote dialogue. Nonetheless, there were notable gaps. Racial and ethnic diversity was often neglected in the studies (addressed in 3 of 19), underscoring the necessity for tailored interventions and methodological considerations for diverse populations. Importantly, dementia caregiving received substantial attention (12 of 19). Final Considerations: This scoping review highlights the growing interest in integrating arts-based methods into caregiving research and interventions amongst qualitative and mixed methods approaches. By mapping out the landscape of existing literature, this review underscores the need for further exploration and methodological refinement to harness the full potential of creative techniques in advancing our understanding of unpaid caregivers' lived experiences. Arts-based approaches hold promise in providing a nuanced and holistic perspective on unpaid caregiving experiences.

Narrative review of immediate salvage for penile prosthesis infection.

Implantation of a penile prosthesis is a reliable option for men with erectile dysfunction (ED) refractory to less invasive therapies. While the frequency of penile prosthesis infections have decreased, they remain a devastating complication. Herein we discuss why immediate salvage surgery is an essential technique for the management of implant infections. We will also describe the relevant advancements to this technique. We conducted a narrative review via computer based search of PubMed for all relevant articles on penile prosthesis infection management, including guidelines, case series, reviews, and expert opinions. Search terms used included: "inflatable penile prosthesis", "IPP", "penile prosthesis", "salvage", "treatment", "delayed", "immediate". Only English peer-reviewed publications were included. Historically, patients who presented with penile prosthesis infections were exclusively managed with complete removal of the prosthesis without replacement. Although this strategy is safe, it hastens immediate ED and corporal fibrosis, resulting in loss of penile length and increased difficulty with subsequent prosthesis replacement. Previous case series have reported successful treatment of localized penile prosthesis infections with nonsurgical treatment, but the role of conservative treatment remains limited. The current standard of immediate salvage entails removal of the infected prosthesis and washout followed by immediate replacement with a new penile prosthesis. This technique has been demonstrated to be safe and effective, thus allowing patients to resume intercourse and maintain penile length. Immediate salvage surgery is safe and effective, and has emerged as the preferred strategy for the management of most patients with a penile prosthesis infection.

Bibliometric Insights into Olympic Weightlifting Research Trends

Prologue: This research paper employs a rigorous bibliometric analysis to illuminate the evolving landscape of Olympic weightlifting research. The dynamic nature of weightlifting movements and their multifaceted impact on athletes form the backdrop of this study. The research identified key themes such as biomechanics, injury prevention, and the psychological aspects of weightlifting. Leveraging the extensive Web of Science database. Methodology: In conducting this bibliometric analysis of Olympic weightlifting research, the database of Web of Science was selected as the primary source of data. A comprehensive search until January 8, 2024, yielded 10,103 articles, focusing on weightlifting, snatch, and clean and jerk. The first method involved utilizing specific keywords related to the subject, while the second method entailed identifying articles in selected journals. For inclusion the criteria were fixed to ensure relevance, including peer-reviewed publications in English. Data cleaning procedures addressed errors such as misspelled author names and variations in author affiliations. The VOSviewer 1.6.19 software facilitated bibliometric analysis, with a specific focus on keyword occurrences and co-occurrence mapping to unveil the intellectual structure of weightlifting research. This methodological approach ensures a systematic and comprehensive examination of the extensive body of literature in the field. Results and Conclusions: The bibliometric analysis presents a vivid snapshot of Olympic weightlifting research trends, showcasing a steady increase in interest over the years. Visualization tools unveil the centrality of "Power" and its robust connections with key concepts like strength and performance. The co-occurrence analysis provides a nuanced understanding of the intellectual structure, emphasizing the multidimensionality of weightlifting studies. These findings underscore the growing role of bibliometric analysis in sports sciences. In conclusion, this research contributes invaluable insights into the evolving landscape of Olympic weightlifting, encapsulating biomechanics, injury prevention, and psychological aspects. The paper serves as a comprehensive resource for researchers, aligning with contemporary discourse and shaping the trajectory of future studies in the field.

Importance of Selected Nutrients and Additives in the Feed of Pregnant Sows for the Survival of Newborn Piglets

This systematic review analyzed the effect of selected nutrients and additives in the feed of pregnant sows on the survival of newborn piglets. We analyzed 720 peer-reviewed publications in English in PubMed® and Web of Science®, dated July 2023 to January 2024, related to the effect of dietary supplementation with fatty acids and various percentages of protein, amino acids, and/or sources of dietary fiber on the offspring of gestating sows. While several papers evaluated the effect of nutrition on gestating sows, only a few delved into the distinct feeding strategies required at each stage of gestation to meet the NRC’s nutritional requirements for maternal tissue gain and postnatal neonatal survival and growth. This body of research suggests that as gestation progresses the sow’s nutritional requirements increase, as the NRC established, to satisfy their own metabolic needs and those of their fetuses. Additional research is needed to determine an optimal feeding strategy.

Climate Change and Violent Conflict in the Middle East and North Africa

Abstract Previous research has demonstrated that climate change can escalate the risks for violent conflict through various pathways. Existing evidence suggests that contextual factors, such as migration and livelihood options, governance arrangements, and existing conflict dynamics, can influence the pathways through which climate change leads to conflict. This important insight leads to an inquiry to identify sets of conditions and processes that make climate-related violent conflict more likely. In this analytic essay, we conduct a systematic review of scholarly literature published during the period 1989–2022 and explore the climate-conflict pathways in the Middle East and North Africa (MENA) region. Through the systematic review of forty-one peer-reviewed publications in English, we identify that society’s ability to cope with the changing climate and extreme weather events is influenced by a range of factors, including preceding government policies that led to the mismanagement of land and water and existing conflict dynamics in the MENA region. Empirical research to unpack the complex and diverse relationship between the climate shocks and violent conflict in the MENA region needs advancing. Several avenues for future research are highlighted such as more studies on North Africa and the Gulf region, with focus on the implications of floods and heatwaves, and exploring climate implications on non-agriculture sectors including the critical oil sector.

Content Focus and Effectiveness of Climate Change and Human Health Education in Schools: A Scoping Review

The creation of standardized, impactful, evidence-based curricula and resources addressing climate change and health issues in schools is seen as vital in combating the impending risks of climate change on human health. A scoping review of the literature was conducted to identify peer-reviewed studies related to climate change and health education in schools and to examine their content focus and evaluation. The search covered five electronic databases and considered English peer-reviewed publications from 2000 to May 2022. Nine studies met the inclusion criteria, representing various countries and employing different study designs. Climate change and health adaptation content dominated the included studies with varying foci, including heatwaves, disaster preparation, flood education, vector-borne diseases, and general climate change and health adaptation. Other studies utilized climate change and health topics to develop skills, employ the use of information and communication technologies within curricula, and highlight the interconnectedness between the environment and health. Although heterogenous in their methodology, the intervention studies and evaluations included (five out of nine) found that interventions impacted knowledge, awareness or perception. Two studies also highlighted the intergenerational learning potential of the interventions. While there is a growing body of research in the field, more research is necessary to measure their effectiveness and thereby develop suitable educational strategies.

P82 Validation of the dermatology life quality index (DLQI): a systematic review of the literature

Abstract The Dermatology Life Quality Index (DLQI) was first published in 1994, and, since that time, it has become the most widely used patient-reported outcome measure worldwide in dermatological studies, owing to its robustness, simplicity and ease of use. This study is the first to review systematically evidence of DLQI validation. MEDLINE, Cochrane Library, Embase, Web of Science, SCOPUS, CINAHL (EBSCO) and PsycINFO were searched for relevant peer-reviewed publications in English, combined into EndNote and filtered for inclusion and exclusion criteria. The study followed PRISMA guidelines, and the study protocol was prospectively published in PROSPERO. A bespoke REDCap database was created, and data from included studies were independently extracted into this by two reviewers. COSMIN guidelines were used to determine bias in studies, and only those studies that reported COSMIN-accepted methods of validation were included. A total of 1262 articles were found from online searches; on screening, 69 met the eligibility criteria, describing 19 216 patients. Studies were conducted in at least 26 different countries, with 13 in the USA, 8 in China, and 5 each in the UK, Brazil and Hungary. Most patients were recruited in hospitals (30.4%), clinics (21.7%) and outpatient departments (10.1%), and 22.5% in other settings; 13.0% was not specified. Twenty-nine studies were multicentred. Most studies (n = 38) collected data specifically for validation, five used data from randomized controlled trials, seven were case–control studies and one was an open-label study. One study was validation of a translation, and five were of cross-cultural adaptation. Psoriasis was the most common disease studied (n = 19; 27%), along with 19 other diseases. The UK English version of the DLQI was used in 18 studies, and 20 other language versions were also used in the other studies. Factor analysis was done in 21 studies, Rasch/item response theory (n = 5), test–retest (n = 14), Cronbach’s alpha (n = 33), known group (n = 19), convergent (n = 10), concurrent (n = 3), divergent (n = 2), content (n = 7), criterion (n = 2) and face (n = 2) validation and responsiveness (n = 15). COSMIN risk of bias showed that few studies met the current rigorous requirements of the guidelines. Extensive evidence of validation of the DLQI is provided to inform researchers’ decisions concerning its use. Recommendations for improving the research methodology and reporting of DLQI validation are also given.

The Use of Telehealth Among People Living With Dementia-Caregiver Dyads During the COVID-19 Pandemic: Scoping Review.

Telehealth has gained substantial attention during the COVID-19 pandemic, and reimbursement policies in health care settings have increased access to remote modes of care delivery. Telehealth has the potential to mitigate care concerns for people living with dementia and their family caregivers. There is a paucity of knowledge on the performance of telehealth services and user experiences, especially among caregiving dyads during the pandemic. This study aims to describe the implementation, effectiveness, user experience, and barriers to accessing and using telehealth services for people living with dementia and their caregivers during the COVID-19 pandemic. Following the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist, we searched 7 databases (PubMed, PsycINFO, AgeLine, CINAHL, Social Services Abstracts, Web of Science, and Scopus) and a web-based search engine (Google Scholar). The inclusion criteria for peer-reviewed English publications from March 2020 to August 2022 consisted of studies related to telehealth services for people living with dementia and their family caregivers and studies conducted during the COVID-19 pandemic. A total of 24 articles (10 quantitative and 14 qualitative studies) from 10 different countries were included. The major findings of the reviewed articles were extracted and organized into the following 4 themes: study design characteristics-strategies were adopted to improve the accessibility and experience of people living with dementia-caregiver dyads; efficacy outcomes of telehealth services-robust evidence is lacking on the comparative effectiveness of in-person services; perceived experiences of people living with dementia and caregivers-most reviewed studies reported positive experiences of using telehealth services and perceived personal and social benefits from their participants; and barriers to accessing and using telehealth services-several barriers related to individuals, infrastructure, and telehealth environments were identified. Although evidence of its effectiveness is still limited, telehealth is widely accepted as a viable alternative to in-person care for high-risk groups, such as people living with dementia and their caregivers. Future research should include expanding digital access for those with limited resources and low technology literacy, adopting randomized controlled trial designs to establish the comparative effectiveness of different modes of service delivery, and increasing the sample diversity.

Living with HIV and Getting Vaccinated: A Narrative Review.

After 40 years of its appearance, human immunodeficiency virus (HIV) infection remains a leading public health challenge worldwide. Since the introduction of antiretroviral treatment (ART), HIV infection has become a chronic condition, and people living with HIV could have life expectancies close to those of the general population. People with HIV often have an increased risk of infection or experience more severe morbidity following exposure to vaccine-preventable diseases. Nowadays, several vaccines are available against bacteria and viruses. However, national and international vaccination guidelines for people with HIV are heterogeneous, and not every vaccine is included. For these reasons, we aimed to perform a narrative review about the vaccinations available for adults living with HIV, reporting the most updated studies performed for each vaccine among this population. We performed a comprehensive literature search through electronic databases (Pubmed-MEDLINE and Embase) and search engines (Google Scholar). We included English peer-reviewed publications (articles and reviews) on HIV and vaccination. Despite widespread use and guideline recommendations, few vaccine trials have been conducted in people with HIV. In addition, not all vaccines are recommended for people with HIV, especially for those with low CD4 cells count. Clinicians should carefully collect the history of vaccinations and patients' acceptance and preferences and regularly check the presence of antibodies for vaccine-preventable pathogens.

Tobacco Cessation and Prevention Interventions for Sexual and/or Gender Minority-Identified People and the Theories That Underpin Them: A Scoping Review.

This scoping review takes stock of the social and behavior change theories that have underpinned tobacco interventions tailored to sexual and/or gender minority (SGM) people and reflects on the need to target contextually based drivers of SGM tobacco use inequities. Data sources were Medline (Ovid), Scopus, PubMed, and Google Scholar (January 01, 1946 to October 27, 2022). Peer-reviewed publications in English from anywhere in the world describing SGM-tailored tobacco cessation and/or prevention interventions were independently identified by a librarian and screened by the first and third authors. Three hundred and sixty-seven articles were extracted; an additional two were found by hand searching. A total of 369 articles were assessed for eligibility. Exclusion criteria were: Not an intervention, review article, not SGM-tailored, or tobacco-focused. We documented the intervention name, intervention components, theoretical frameworks cited in reference to intervention design and/or implementation, and evaluation outcomes. All authors provided input on theoretical framework categorization. We identified 22 publications corresponding to 15 unique interventions. Individual-level behavior change theories (ie, those focusing on within-person behavior change processes) were the most prominent. Among these, the Transtheoretical Model was the most frequently utilized, while Social Inoculation Theory, Theory of Reasoned Action, and Theory of Psychological Reactance were also employed. A minority of interventions referenced frameworks that more explicitly engaged with SGM people's social contexts, namely, Theory of Diffusion of Innovations and Minority Stress Model. Future SGM-tailored tobacco interventions should leverage both the strengths of individual-level behavior change theories and those of frameworks that understand tobacco use inequities as indivisible from place, context, and policy. This scoping review describes the theoretical underpinnings of sexual and/or gender minority (SGM)-tailored tobacco interventions published in the peer-review literature in English. It reflects on the need for greater utilization of social and behavior change theoretical frameworks that can engage with unique drivers of SGM tobacco use and barriers to cessation.

Suicide Risk Help-Seeking Among Middle- to Old-Age Adults: A Systematic Review.

Suicide has become a major public health concern worldwide and in the United States. Rates of suicide increase during the life course and are highest among middle- to old-age adults. Help-seeking represents a crucial coping mechanism that can mitigate suicide risk. Yet, less is known about suicide risk help-seeking, especially among these age groups. To address this knowledge gap, a systematic review of existing literature was performed to obtain a refined understanding of help-seeking for suicide risk among middle- to old-age adults. Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, electronic databases and key journals with suicide and/or gerontology focuses were searched to identify peer-reviewed publications in English between 2010 and 2020. A total of 4 732 unduplicated publications were screened for relevance based on titles and abstracts, of which 52 were reviewed in full text. Twenty-four articles met inclusion criteria and were included in the qualitative synthesis. These articles discussed a range of topics, including the prevalence of service utilization, service use prior to a suicide death, and correlates of help-seeking. In general, the prevalence of service utilization was low and varied by suicidal history (eg, higher prevalence among individuals with a history of suicide attempts than those with suicide ideation only). Key facilitators (eg, current or history of suicidal thoughts, plans, or attempts) and barriers (eg, stigma) for service use and help-seeking were also identified. Findings highlight the need for future studies and tailored services to improve age-appropriate and culturally responsive suicide prevention and intervention strategies for middle- to old-age adults.

Using health information technology to support the needs of Children with Medical Complexity: Mapping review of consumer informatics applications.

Children with medical complexity (CMC) are fragile populations that require continuous care and supervision. CMC family caregivers experience many challenges trying to address CMC patients' needs which puts these caregivers in a stressful situation that may negatively impact the care of CMC patients. Consumer informatics might help these caregivers in coordinating care. However, few consumer informatics applications explicitly focus on supporting CMC caregivers' needs. This systematic mapping literature review aims to provide an overview and a structured understanding of the consumer informatics designed for CMC and their caregivers. We followed a systematic mapping literature review process to provide an overview of the existing Consumer Informatics literature for CMC, which is the scope of our study. We screened IEEE Xplore, Web of Science, and PubMed databases using a preset list of mesh terms that cover the use of medical informatics by children with medical complexities and their caregivers. The selected articles are peer-reviewed English publications that were empirically validated from January 2002 to January 2022. After selecting and filtering the articles, we analyzed them based on the preset mapping questions using the following criteria: publication year, publication source, research type, contribution type, empirical type, the need addressed, target audience, technology users, and consumer informatics' type. The initial search resulted in a number of (N = 2,275) articles, and 17 selected publications were included. The results showed an increasing interest in CMC consumer informatics publications over time. Most of the studies were published in 2021, and feasibility research is the dominant research type. The most used technology was telehealth and telemedicine, followed by mobile health. The technologies addressed various needs, including; coordination & follow-up, medical safety, education & social support, daily living activities, shared decision making, information seeking, and emotional support. Most of the efforts were focused on ensuring good coordination and follow-up. CMC consumer informatics is a promising research field to present novel initiatives and approaches to manage the caregivers' workload. Future research should be shifted toward providing more evidence-based studies to examine the effectiveness of CMC consumer informatics solutions and identify the related challenges and limitations.

HELP-SEEKING FOR SUICIDE RISK AMONG MIDDLE- TO OLD-AGE ADULTS

Abstract Suicide is a major public health concern. Suicide rates have increased steadily in the U.S. and are highest among middle-aged (ages 45-64) and older (age 75+) adults. Help-seeking represents an important coping behavior that can mitigate suicide risk. However, research on this topic is sparse, especially among older adults. To address this gap, a systematic review of the existing literature describing help-seeking for suicide risk among middle- to old-age adults was conducted. Using PRISMA guidelines, we searched electronic databases (e.g., ProQuest, EBSCOhost, PsycINFO, PubMed, Medline) and key journals with suicide and/or gerontology focuses for peer-reviewed publications in English between 2010-2020. The search yielded 4,732 unduplicated publications. After screening articles for relevance based on titles and abstracts, 52 articles were reviewed in full text. A total of 24 articles met inclusion criteria and were included in this review. The articles reviewed included a range of topics, including prevalence of service utilization, service use prior to suicide-related behaviors, and correlates of help-seeking. Overall, prevalence of service utilization was generally low and varied by suicidal history (e.g., greater prevalence among those with a history of suicide attempt, as compared to those with suicide ideation but no attempts). The systematic review also identified key service use facilitators (e.g., higher suicide literacy, previous or current suicidality) and barriers (e.g., stigma). Results of this systematic review highlight the need for future research and tailored services to improve suicide prevention and intervention strategies for middle-aged and older adults.

Nurse-Led Telehealth Interventions During COVID-19: A Scoping Review.

Since the outbreak of COVID-19, telehealth expanded rapidly and was adopted as a substitute for in-person patient and nurse visits. However, no studies have mapped nurse-led telehealth interventions during the pandemic. This study aimed to identify and summarize the strengths and weaknesses of nurse-led telehealth interventions for community-dwelling outpatients during the COVID-19 pandemic. This study used a scoping review methodology and was guided by the Preferred Reporting Items for Systematic Reviews and Meta-analyses Scoping Review Extension. Five electronic databases were searched to find studies published in English peer-reviewed publications between January 2020 and February 2022. A total of 490 articles were retrieved, of which 23 empirical studies were selected based on the inclusion/exclusion criteria. Primary studies from nine countries with a variety of research designs were included. Four strengths and three weaknesses of nurse-led telehealth interventions for patients during COVID-19 were identified. For telehealth services to provide effective, efficient, and quality patient care, future research and nursing practice need to overcome the identified weaknesses of current nurse-led telehealth interventions. More rigorous evidence-based research and updated and standardized guidelines for nurses' telehealth services will help improve the quality of patient care. Nurse managers, leaders, and policymakers can use the findings of this scoping review to refine the current telehealth services system.

Linkages of organizational commitment and leadership styles: a systematic review

PurposeThis paper aims to examine how the linkages between organizational commitment (OC) and five leadership styles, namely, authentic leadership, benevolent leadership, ethical leadership, moral leadership and spiritual leadership, have been investigated in the literature.Design/methodology/approachThis systematic literature review applies a matrix method to examine the significant literature in leadership and OC, specifically considering themes of self-development, self-awareness, self-regulation, self-discipline and self-motivation necessary for individuals and organizations. The papers from Australian Business Deans Council, Scopus and Web of Science listed journals were reviewed. Forty-three peer-reviewed English publications from 20 journals were selected and analysed.FindingsThe synthesis of these empirical studies revealed that the relationship between OC and these leadership styles had primarily been mostly quantitatively investigated in many countries and sectors. Additionally, ethical leadership remains the most commonly researched style. Furthermore, there are mediating mechanisms and boundary conditions in the relationship between these styles and OC.Research limitations/implicationsThe literature search in this study was mainly focused on English articles only; therefore, some papers in other languages may not have been included. Additional qualitative studies based on these linkage themes need to be conducted in human resource development (HRD) contexts.Practical implicationsThis review offers an overall picture of the existing knowledge of OC and leadership that will be fruitful for HRD practitioners to understand and replicate these concepts.Originality/valueThere are few systematic literature reviews on the relationship between OC and leadership styles. This paper is among the first systematic reviews to analyse how leadership has been associated with OC and provides potential research directions. HRD practitioners and academia should find the results of this study helpful.

Rapid molecular testing for antimicrobial stewardship and solid organ transplantation.

Several molecular platforms now exist for early detection of infectious pathogens. In this review, we present the currently available literature summarizing clinical outcomes using rapid diagnostic tests (RDTs) in the solid organ transplant (SOT) population. We also present potential benefits and drawbacks of these technologies for SOT patients. We completed a PubMed search querying for 31 specific RDTs AND ("SOT"). We also queried PubMed for studies on RDT outcomes in the general population. References of the resulting relevant studies were reviewed and incorporated if the study population included at least one SOT patient. All culture specimen types were included. Only full-text peer-reviewed publications in English were examined. Our search yielded eleven studies. Across these studies, integrating RDTs with ASP intervention led to faster species identification and susceptibility results, faster time-to-optimal therapy, decreased hospital length-of-stay and costs, and decreased mortality. Potential drawbacks of RDTs in the SOT population included: overdiagnosis due to increased sensitivity (i.e., Clostridium difficile), decreased yield of tests for respiratory pathogens, and lack of identification of important pathogens in this population such as, Aspergillus species. Although there is a scarcity of studies involving SOT patients, current available data suggests that the use of RDTs helps improve patient outcomes and minimizes inappropriate antimicrobial use when coupled with proactive ASPs. Future studies should focus on clinical outcomes in SOT patients specifically, as well as how to optimize the use of RDTs in conjunction with traditional microbiology methods.

Effect of Visiting Restrictions in the NICU during the Pandemic: A Literature Review

Background: Parents of infants in the neonatal intensive care unit (NICU) experienced a tremendous amount of stress with the changing policies which added to the trauma of having an infant in the NICU. While family-centered and developmental care are the norms in the NICU, the ‘visiting’ policy that involved complete lockdown, one parent at a time, restrictions on partners and extended families including grandparents, no kangaroo care, no breastfeeding, … etc. affected women emotionally, impacting breast milk production, breastfeeding and increased incidence of postpartum depression. Purpose: The purpose of this literature review is to explore the consequences of visiting restrictions in NICUs during the pandemic. Methods: Search terms, such as NICU, neonatal intensive care unit, parents, COVID-19 and visit, were used to search databases, such as CINAHL, PubMed and EBSCOhost, to identify peer-reviewed publications in English. The publications were after March 2020 by nature of the topic. Results: Visiting restrictions have a ripple effect on the infant and the family, where breastfeeding, milk production and parental mental health were affected. The changing policies have affected nurses too. Conclusion: Families are affected by the rapidly changing visiting policies during the COVID-19 pandemic. This has a ripple effect on mental health, bonding, breast milk production and family dynamics. Implications for Nursing: Babies born during these challenging times must be followed-up for their developmental milestones and social and educational achievement. Keywords: Neonatal intensive care unit: NICU, Parents, Visit, Pandemic, COVID-19.

Upadacitinib for the Treatment of Rheumatoid Arthritis: An Extensive Review.

To review the characteristics, efficacy, safety, pharmacoeconomics, and place in therapy of upadacitinib, a Janus kinase (JAK) inhibitor, in the treatment of rheumatoid arthritis (RA). PubMed (January 2003-May 2022) was searched using upadacitinib and ABT-494. Human studies published in peer-reviewed publications in English were the primary sources for efficacy and safety data. In randomized, double-blind, controlled clinical studies, upadacitinib demonstrated statistically significant improvement in RA symptoms as monotherapy and in combination with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) when compared with csDMARD monotherapy or to adalimumab or abatacept in combination with csDMARD therapy in patients with RA. American College of Rheumatology 20% response rates were 68% to 79% for upadacitinib monotherapy and 64% to 84% for upadacitinib plus csDMARD therapy, compared with 28% to 59% for csDMARD-only therapy and 63% to 74% for biologic DMARD (bDMARD) plus csDMARD therapy. Long-term extension studies demonstrated similar findings. Upadacitinib had similar rates of serious infections, herpes zoster, major cardiovascular events, and venous thromboembolic events as other JAK inhibitors. Upadacitinib was similar in cost to tofacitinib and twice as high as baricitinib based on current estimated costs to patients, but actual costs may vary. Upadacitinib is an alternative therapy to other JAK inhibitors and bDMARDs in patients with moderate to severe RA who have had an inadequate response to a tumor necrosis factor inhibitor alone or in combination with a csDMARD. Upadacitinib is an effective JAK inhibitor for use in RA.

Urban Interventions and Participation Tools in Urban Design Processes: A Systematic Review and Thematic Analysis (1995 – 2021)

All cities need to change and transform to become more livable. Urban interventions are effective for observing the changes and participation tools are in use for collecting data from urban contexts. Nevertheless, the two research fields remain thematically disintegrated within themselves and between each other in the literature that spread across disciplines. This article aims to contribute to and advance the academic conceptualization of urban interventions and participation tools within urban design processes. In order to establish a solid basis and provide conceptual clarity, the research domains of two study fields are explored from 1995 through 2021. We conducted a thematic analysis covering 176 peer-reviewed publications in English. The studies on urban interventions are synthesized and categorized into five main thematic areas: urbanism, community, sustainability, building types, and participation; while the studies on participation tools are investigated within four thematic areas: participation, digital tools, representations, and responsive cities. We conclude that the two research fields are highly interrelated and need to be studied together. This systematic review would trigger new perspectives and directions in the future, and provide a well-conceptualized base that combines urban interventions and digital participatory designs for both theory-based and practical studies.

Pulmonary Post-Acute Sequelae of COVID-19

Introduction: Persistent symptoms have been observed in a substantial proportion of survivors of COVID-19 since relatively early in the pandemic. Among these post-acute sequelae of COVID-19 (PASC), respiratory symptoms appear to be the most prevalent. Methods: We conducted a literature review of peer-reviewed publications in English on the clinical and epidemiological features of respiratory PASC in cohorts of 100 or more patients with a follow-up of four weeks or more after acute infection. Included studies reported the prevalence of persistent respiratory symptoms and/or the results of follow-up pulmonary function tests. Results: On our review included 14 studies across eight countries with a total of 2,380 patients. Subacute PASC was reported in 876 patients, and chronic PASC in 1,504 patients. The median age ranged from 44 to 67 years. The most common symptoms observed were fatigue (44%), dyspnea (40%), and cough (22%). Lung disease as a comorbidity was found in 13% of patients on average. Predominance of males was seen in all studies of subacute PASC and six out of eight studies of chronic PASC. The rates of comorbidities for subacute vs. chronic PASC were: hypertension 32% vs. 31%, cardiovascular disease 10% vs. 7%, diabetes mellitus 15% vs. 12%, kidney disease 7% vs. 4%, and lung disease 19% vs. 10%. Conclusion: Respiratory PASC seems to be more predominant as a chronic presentation, more common in male adults, and less common in older persons. Respiratory PASC is most often associated with fatigue, dyspnea, and cough. There was no strong correlation of severity of illness, acute respiratory distress syndrome, or intensive care unit admission with respiratory PASC.