Patients Undergoing Open Heart Surgery Research Articles

Effect of Cross Clamp Duration on GFR and Creatinine Values Due to Renal Flow in Valve Patients Undergoing Open Heart Surgery

Effect of Cross Clamp Duration on GFR and Creatinine Values Due to Renal Flow in Valve Patients Undergoing Open Heart Surgery

Effect of a Nurse-Led Cognitive-Behavioral Therapy on Sleep Quality in Patients Undergoing Open Heart Surgery: A Prospective Randomized Clinical Trial

Background: Sleep disorders are one of the most common complications in patients undergoing open-heart surgery. Cognitive-behavioral therapy (CBT-I) is used as a way to improve sleep quality. Objectives: This study aimed to determine the effect of a nurse-led CBT-I on sleep quality among patients undergoing open-heart surgery. Methods: This prospective randomized clinical trial was conducted on 90 patients undergoing open-heart surgery in both intervention and control groups (N = 45). The control group received routine care. The intervention group received 10-12 sessions of nurse-led CBT-I. The demographic questionnaire and the Pittsburgh Sleep Quality Index (PSQI) were used to collect data. The data was analyzed in SPSS v. 22 software using X2, independent sample t -test, analysis of covariance (ANCOVA), and paired t-test. Results: The majority of samples were in the age range of 31 - 40 years (33.33%) and male (53.33%). The results of the independent t-test showed that the mean total PSQI score in the 2 groups before the intervention was not significantly different (P = 0.245). Also, the results of ANCOVA showed that the mean total PSQI score after the intervention has a significant difference in the 2 groups (P = 0.0001). Conclusions: Nurse-led CBT-I intervention helps to improve the sleep quality of patients after open-heart surgery by reducing their automatic thoughts that affect behavior. Thus, it is recommended that training in nurse-led CBT-I be included in the nurses' academic training program, as well as in continuing education programs for nurses working in heart surgery wards.

Effect of Age on Estimated Glomerular Filtration Rate and the Relationship between eGFR and Extubation Time in Patients Undergoing Open Heart Surgery

Effect of Age on Estimated Glomerular Filtration Rate and the Relationship between eGFR and Extubation Time in Patients Undergoing Open Heart Surgery

Practices of Physical Therapist Regarding Chest Physiotherapy for Patients Undergoing Open Heart Surgery in Karachi

Background: Despite the critical role of chest physiotherapy in the recovery process post open-heart surgery, there is a paucity of data on the practices of physical therapists in Karachi. With the high incidence of cardiovascular surgeries and the significant burden of postoperative complications, understanding current physiotherapy practices is essential for improving patient outcomes. Objective: The objective of this study was to evaluate the current practices of physical therapists regarding chest physiotherapy for patients undergoing open-heart surgery in Karachi and to identify potential areas for standardization and improvement. Methods: A cross-sectional study was conducted using a questionnaire survey among 40 physiotherapists working in cardiothoracic units across six major hospitals in Karachi. Participants were selected through non-probability convenient sampling, and data on preoperative and postoperative physiotherapy practices were collected. The survey included both open-ended and close-ended questions, with an emphasis on the types of treatments administered during the first five postoperative days. Statistical analysis was performed using SPSS version 25. Results: The mean age of the physiotherapists was 31.20 (SD = 6.8) years with an average working experience of 7.592 (SD = 6.7) years. On the day of surgery, physiotherapy was provided routinely by 7.5%, as needed by 62.5%, and was never provided by 30% of the respondents. From the first to the fifth postoperative day, routine physiotherapy was administered by an increasing majority, peaking at 100% on the second day. Written guidelines for the management of extubated and intubated patients were accessible to 35% and 10% of participants, respectively. Conclusion: There is a substantial engagement in chest physiotherapy post open-heart surgery among physiotherapists in Karachi. However, the variability in practice and the lack of standardized guidelines point towards a need for the development and implementation of standardized protocols to ensure consistent and evidence-based care.

Factors Affecting Death Anxiety in Patients Undergoing Open Heart Surgery: A Cross-Sectional Study.

After the operation, death anxiety of patients is affected by many factors. This study aims to investigate the factors affecting death anxiety of patients undergoing open heart surgery. A descriptive, cross-sectional study. Data were collected using the 'Introductory Information Form,' the 'Templer's Death Anxiety Scale,' and the 'Spiritual Well-being Scale.' This study was conducted with 313 intensive care patients. The mean scores of the patients on the "Death Anxiety Scale" were moderate (7.96 (4.28)). According to the study findings, age, gender, length of stay in the intensive care unit, and spiritual well-being were found to be important predictors of death anxiety (F (4,308) = 16.149, p < .001). Considering gender differences in nursing care, it is thought that the intensive care period will be shortened, the level of spiritual well-being will increase and death anxiety will decrease.

Factors Affecting the Mortality of Patients Undergoing Open Heart Surgery with Cardiopulmonary Bypass at Dr. M. Djamil General Hospital, Padang, Indonesia

Background: Morbidity and mortality of patients after cardiac surgery can be influenced in the preoperative, intraoperative, and postoperative periods. This study aimed to explore factors that affect the mortality of patients undergoing open heart surgery with cardiopulmonary bypass at Dr. M. Djamil General Hospital, Padang, Indonesia.&#x0D; Methods: This study is an analytical observational research with a cross-sectional approach and uses secondary data obtained from the medical record installation of Dr. M. Djamil General Hospital, Padang, Indonesia. A total of 57 research subjects participated in this study. Univariate, bivariate, and multivariate analyses were carried out using SPSS software.&#x0D; Results: The final multivariate modeling results show that the variables that influence patient mortality are EuroSCORE II (p-value=0.003) and duration of CPB (p-value=0.003). With an odds ratio of 37.21 groups, EuroSCORE II high risk had a risk of death 37.21 times higher than the low-risk group (CI 3.325 – 416.324). Meanwhile, increasing the duration of CPB by one minute increased the risk of mortality 1.02 times (CI 1.006 – 1.030). Meanwhile, there is no influence of variables (NYHA, LV function, ACC duration) on the incidence of mortality in patients undergoing open heart surgery with a machine cardiopulmonary bypass at Dr. M. Djamil General Hospital, Padang.&#x0D; Conclusion: EuroSCORE II affects the mortality of patients undergoing open heart surgery with CPB. The duration of CPB affects the mortality of patients undergoing open heart surgery with CPB.

Modified Ultrafiltration and Acute Kidney Injury in Patients Undergoing Open Heart Surgery Using Cardiopulmonary Bypass

Objective: To determine the incidence of acute kidney injury (AKI) in patients undergoing open heart surgery using cardiopulmonary bypass (CBP) with and without modified ultrafiltration (MUF). Materials and Methods: A total of 150 patients who underwent open heart surgery using CPB in our hospital from Jan-2022 to Dec-2022. In group A patients MUF was performed during the CPB and atleast 1000 ml of volume was removed using MUF. While in group B patients, no filtration was performed during CPB. In ICU all patients were followed till three days after surgery to determine the incidence of AKI. Results: Mean age was 53.4±10.9 years in MUF group versus 55.6±11.8 years in control group, p-value 0.23. Majority, 53 (70.7%) patients were male in MUF and 57 (76%) in control group, p-value 0.55. Mean CPB time was 101.6±45.2 mins in MUF and 96.5±39.1 mins in control group, p-value 0.46. Mean X-clamp time was 47.5±19.3 mins in MUF and 51.4±21.6 mins in control group, p-value 0.43. The incidence of AKI was comparable, with frequency rate of 3 (4.0%) in MUF group versus 1 (1.3%) in control group, p-value 0.31. Conclusion: In present study, the incidence of AKI in MUF and control group was almost similar. So according to the results of present study, the use of MUF has no role in preventing or aggravating AKI in patients undergoing CPB. Keywords: Acute kidney injury, cardiopulmonary bypass, modified ultrafiltration.

Comparison of The Effect of Using Back Massage with Hand and Warm Towel on Muscle Pain and Pulmonary Function of Patients Undergoing Open Heart Surgery Hospitalized in Selected Military Hospital in Shiraz

Comparison of The Effect of Using Back Massage with Hand and Warm Towel on Muscle Pain and Pulmonary Function of Patients Undergoing Open Heart Surgery Hospitalized in Selected Military Hospital in Shiraz

Assessment of Patients' Needs Pre and Post Open Heart surgery

Background: Assessment of Bio-psychosocial needs of patient pre and post open heart surgery are very important aspect of patient centered care. Aim: was to assess patients' needs pre and post Open Heart Surgery. Design: -A descriptive exploratory design was utilized in this study. Settings: This study was conducted at Cardio-Thoracic Intensive Care Unit of Educational Tanta University Hospital. Subjects: A convenience sample of (100) open heart surgery patients that had been admitted to Cardio-Thoracic Intensive Care unit and meeting the inclusion criteria. Tools of the study: Two tools was used in this study for data collection: Tool I:A structured Interview Schedule Tool II:Bio psychosocial Needs Interview Questionnaire which included three parts; part (1): Physical Needs for Patients undergoing Open Heart Surgery, part(2): Psychological Assessment for Patients with Open Heart Surgery and part (3) Social Dysfunction Rating Scale for Patients with Open Heart Surgery. Results: There was highly significant positive correlation between total Social Dysfunction of the studied patients and their total score of pain score and total score of psychological needs at (P= < 0.01). In addition, there were significant positive correlation between total score of pain score of the studied patients and their total score of psychological needs and total score of Social Dysfunction at (P= < 0.01). Conclusion: The study concluded that, three-quarters of the studied patient had unsatisfactory level of total knowledge about heart surgeries. Also, there was a marked increase in total patients’ dependency in Activities of Daily Living level at post heart surgery. Recommendations: Routine pre and postoperative assessment of patients who are undergoing open heart surgery is recommended to identify the different patient's biopsychosocial needs and consequently any risk factor and reduced the post-operative complications.

Investigation of Anxiety, Depression and Perceived Caregiving Burden in Parents of Pediatric Patients Undergoing Open Heart Surgery and Being Followed Up in Intensive Care

Introduction: This study aims to investigate the relationship between anxiety levels and perceived caregiver burden in mothers of children who had undergone congenital heart disease surgery and who were followed up in the intensive care unit with the surgical type and clinical variables applied. Patients and Methods: The study was conducted with the mothers of both patient groups who underwent palliative surgery (n= 32) or corrective (biventricular) repair (n= 35) in the pediatric cardiovascular surgery clinic of Kartal Koşuyolu High Specialization Training and Research Hospital. Sociodemographic-clinical data form, Beck depression inventory, standardized mini-mental test, State-Trait Anxiety Inventory (STAI TX I-II), and Zarit Burden Interview (ZBI) were applied to the parents. Results: The rate of interventional birth was higher in the palliative surgery group whereas there was no difference between the palliative surgery and corrective repair groups in terms of age, gender, birth weights, and presence of additional diseases (p= 0.001). There was no difference between maternal education levels and pregnancy duration. This difference was not significant even though the mean age of the mothers in the corrective repair group was higher compared to the palliative surgery group. The mean STAI-S scores of the palliative surgery group (state anxiety) were lower than the corrective repair group, and the STAI-T scores of the palliative surgery group (trait anxiety) were higher. The ZBI scores were significantly higher in the palliative surgery group (p= 0.03). Conclusion: Congenital heart diseases and surgical interventions, as a result, are a major source of distress for affected families. Mothers are mainly affected by this situation. Changes in the mental status of the caregiver may have serious adverse effects on the operated child at every stage of the disease. Caregiving in parents is perceived as a burden and increased anxiety leads to different psychiatric clinical manifestations. Therefore, it is recommended that parents of children who have undergone congenital cardiac surgery receive routine psychiatric support from the early stages of the disease.

Potency Adjusted Bovine Heparin is Comparable to Porcine Heparin in Patients Undergoing Open Heart Surgery

IntroductionHeparin obtained from bovine intestinal mucosa is being considered for reintroduction in cardiovascular, surgical, and interventional procedures. Although the anticoagulant potency of bovine heparin is weaker (130–140 U/mg) than that of porcine heparin (180–200 U/mg), when potencies are adjusted to equivalent USP U/mL activity, both porcine and bovine heparin exhibit comparable anticoagulant activities in in‐vivo and in‐vitro settings.AimThe primary aim of this study was to compare bovine and porcine heparins at equivalent dosing in terms of anticoagulation and potential bleeding effects in patients undergoing coronary artery bypass graft (CABG) surgery.Materials and MethodsCoagulation parameters and biomarkers of inflammation were measured in 32 patients included in a single center, blinded, controlled clinical trial, randomized to CABG surgery with either bovine or porcine heparin. Equivalent dosages of 28,500 units (potency adjusted to 10,000 U/mL) total dose heparin were used. Blood samples were collected at multiple times during and after surgery to measure global clotting activity (ACT, APTT) and amidolytic anti‐Xa levels. TNFa, IL‐6, and TFPI antigen were measured by ELISA; activated protein Cwas measued by a clot‐based assay. A preliminary report of these results has been published (Int J Cardiol 223:611–612, 2016).ResultsAll coagulation parameters (ACT, APTT, anti‐Xa, residual bleeding) demonstrated comparable heparinization (p ≥ 0.05). The only difference between groups was an increased amount of protamine required to neutralize bovine heparin after surgery determined by ACT; expected due to the higher gravimetric quantity of bovine heparin used to adjust the U/mL potency. No differences were found between groups in levels of acute inflammatory markers (p ≥ 0.05).ConclusionThis study shows that bovine and porcine heparins at potency adjusted dosages are equivalent anticoagulant drugs in CABG surgery resulting in comparable perioperative coagulation, bleeding, and anti‐inflammatory effects.Support or Funding InformationNone.This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.

Effect of Intravenous Dexmedetomidine Infusion on Interleukin-6 (IL-6) and Plasma Cortisol in Open Heart Surgery

Aim of the work: to evaluate the effect of intravenous dexmedetomidine infusion on patientsundergoing open heart surgery regarding stress response markers as plasma interleukin-6 andplasma cortisol.Patents and Methods: Fifty consecutive patients aged 18-70years, scheduled for elective openheart surgery using CPB technique were enrolled in this study at the Cardiothoracic Surgery Unit,Luxor international hospital, from July 2018 to May 2019. Patients randomly assigned using closedenvelope technique into two equal groups according to the drug infused intraoperatively: 1st group (25 patients):- Dexmedetomidine group (Group D); received loading dose of intravenousdexmedetomidine infusion of 1 μg/kg IV dissolved in 20ml normal saline over 10 minutes followedby maintenance dose of 0.5 μg/kg/hr. till the end of surgery where 0.5 μg /kg/h was calculated foreach patient and dissolved in 12.5 ml normal saline 2nd group ( 25 patients):- placebo group (Group P); receive 20ml intravenous infusion of normal saline 0.9 % over 10 minutes followed bycontinuous infusion of 12.5 ml of normal saline till the end of surgery.Results: Our study revealed that HR and MAP wasn’t significantly different between the twogroups at the baseline, but significantly lowered in Dex. group after induction, during CPB, postCPB, and postoperative.Dexometomedine suppress the intraoperative and postoperative rise of IL-6which was significantly higher in placebo group relative to Dex. group. Also dexometomedine haseffect on stress hormone as serum cortisol and serum glucose decease in Dex. group relative toplacebo group. None of studied cases revealed bradycardia or hypotention and there are nosignificant difference between groups regarding side effect drowsiness, nausea and vomitingConclusion: This study demonstrated that the continuous administration of dexmedetomidineduring open heart surgery with CPB suppressed intraoperative and post-operative cytokinesecretion, and improved post-operative inflammatory response indices in the present study. Also itstabilize blood pressure and heart rate and blunt cardiovascular response to CPB. These resultscould be attributed to the anti-inflammatory effects of dexmedetomidine.

Incidence and Predictors of Permanent Pacing in Patients Undergoing Open Heart Surgery for Infective Endocarditis

Incidence and Predictors of Permanent Pacing in Patients Undergoing Open Heart Surgery for Infective Endocarditis

Açık Kalp Cerrahisi Geçirecek Hastaların Taburculuk Sonrası Öğrenme Gereksinimleri

Açık Kalp Cerrahisi Geçirecek Hastaların Taburculuk Sonrası Öğrenme Gereksinimleri

219 Effect of Training Program Regarding Care of Patients Undergoing Open Heart Surgery on Nurses' Performance Approach

Background: Open heart surgery is a common interventional procedure for ischemic and valvular heart disease which is accompanied by postoperative care. Considering this aim of the study was framed to evaluate the effect of nursing training program regarding care of patients undergoing open heart surgery on nurses' performance. Subjects and Method: A quasi- experimental research design was used to conduct this study. A representative sample of 30 nurses, whom dealing with open heart surgery patients were selected from the Mansoura University Hospital. Two tools were used for data collection; nurses interview sheet, and nursing practice observational Checklist. The results of the present study found that, there was a significantly improvement in nurses’ knowledge and practice concerning to open heart surgery after implementation of open heart surgery nursing care training program, frequency of this improvement of nurses according to their total knowledge score at follow up phase was (73.3%) and frequency of this improvement of nurses according to their total practice score at follow up phase was (60.0%). There was a positive correlation between nurses total knowledge score and their total practices score in pre, post and follow up phases of implementing training program. Hence the study concluded that the training program had a significant positive impact on nurses’ knowledge and practice concerning to open heart surgery after implementation of the training program. The study recommended: A training programs should be organized for the nurses to improve their knowledge and practice regarding open heart surgery nursing care, feedback should be done as well as booklets about open heart surgery should be available in cardiothorathic department in the hospital

Effect of Telephone Follow-up Care on Rehospitalization and Depression in Patients Undergoing Open Heart Surgery in a Selected Military Hospital

Effect of Telephone Follow-up Care on Rehospitalization and Depression in Patients Undergoing Open Heart Surgery in a Selected Military Hospital

Comparison of the Effects of Aromatherapy with Rose and Lavender on Physiological Parameters of Patients Undergoing Open Heart Surgery: A Clinical Trial

Comparison of the Effects of Aromatherapy with Rose and Lavender on Physiological Parameters of Patients Undergoing Open Heart Surgery: A Clinical Trial

Effect of Beloved Person’s Voice on Chest Tube Removal Pain in Patients undergoing Open Heart Surgery: Fuzzy Logistic Regression Model

Chest tube removal pain is one of the important complications after open heart surgery. The removal of a chest tube is a painful and frightening experience and should be managed with as little pain and distress as possible. The aim of this study is to assess the effect of beloved person’s voice on chest tube removal pain in patients undergoing open heart surgery. 128 patients were randomly assigned to two groups: one group listened to beloved person’s voice during the procedure, and the other did not. Since pain was measured by linguistic terms, a fuzzy logistic regression was applied for modeling. After controlling for the potential confounders, based on fuzzy logistic regression, the beloved person’s voice reduced the risk of pain. Therefore, using beloved person’s voice could be effective, inexpensive and safe for distraction and reduction of pain.

The Influence of Tranexamic Acid on Platelet Function in Patients Undergoing Open Heart Surgery Using Cardiopulmonary Bypass (CPB)

The Influence of Tranexamic Acid on Platelet Function in Patients Undergoing Open Heart Surgery Using Cardiopulmonary Bypass (CPB)

Comparison of Glucometry and Venous Blood Sugar Results in Diabetic Patients Undergoing Open Heart Surgery with Hemodynamic Instability

Comparison of Glucometry and Venous Blood Sugar Results in Diabetic Patients Undergoing Open Heart Surgery with Hemodynamic Instability