Paternal Perinatal Depression Research Articles

Assessment of the validity and reliability of edinburgh postpartum depression scale in Turkish men.

Perinatal depression (PD) affects individuals during pregnancy and early parenthood, resembling major depression. Recent research highlights paternal perinatal depression (PPD) in fathers. PPD has adverse effects on fathers and their children. This study assesses the Turkish version of the Edinburgh Postnatal Depression Scale (EPDS) for Turkish fathers, aiming to provide a tool for PPD identification. This methodological study validates the EPDS for Turkish fathers and explores associations with demographic and psychosocial factors. The study involved 295 fathers withinfants aged 2weeks to 12months. The EPDS, originally designed for perinatal depression and validated in Turkish women, was used. Fathers completed a participant information questionnaire, the EPDS, and the Beck Depression Inventory (BDI) during clinic visits. Data on sociodemographic factors, paternal roles, and pregnancy and postpartum support were collected. Mothers also completed the EPDS. Descriptive statistics, exploratory factor analysis, confirmatory factor analysis, and correlation tests were used. The study included fathers with an average age of 30.5 years, mostly with a high school education or higher. The EPDS had a mean total score of 3.1. Factor analysis suggested a three-factor structure for the EPDS in Turkish fathers, including anhedonia, anxiety, and depression. Confirmatory factor analysis validated the three-factor structure, with acceptable model fit indices. Positive correlations were found between fathers' EPDS scores, maternal EPDS scores, and paternal BDI scores. The EPDS effectively discriminated between different levels of depression severity. Various factors, such as education level and lack of support during pregnancy and after childbirth, were associated with higher EPDS scores. These findings emphasize the significance of assessing and addressing PPD in fathers, supporting the use of the EPDS as a valid tool in the Turkish context. The three-factor structure aligns with international research, highlighting the importance of a multi-dimensional approach to PPD assessment. Early intervention can mitigate PPD's impact on fathers, mothers, and children, benefiting mental health and well-being.

Paternal perinatal depression: underestimation of the disorder, its clinical and classificatory entanglements, and therapeutic alternatives

In the perinatal period, fathers may also suffer from depression, referred to as paternal perinatal depression. Studies have shown that the prevalence of paternal perinatal depression is considerably higher than in the general adult population. For example, a meta-analysis showed that the prevalence of depression among fathers was 9.76% during the prenatal period and 8.75% during the postpartum year.1 Paternal perinatal depression can deteriorate the marital relationship and generate psychosocial and behavioral problems in the offspring (Ramchandani et al., 2021).2 However, paternal perinatal depression has received comparatively little clinical attention. A review of the literature on this subject will list the biological, psychological and social risk factors for this condition, which include a history of depression or anxiety disorders, lack of social support, conflicts in the couple's relationship, economic and labor problems. The clinical characteristics of depression share similarities with depressions in other periods of life, and there are differential clinical features, such as anger, aggressiveness, somatic symptoms and greater comorbidity with substance abuse disorder. Early detection with scales such as the Edinburgh, Gotland and PAPA and the appropriate approach are fundamental to mitigate the effects of paternal perinatal depression. Psychotherapeutic support, psychoeducation of the disorder, and self-care tools can be part of a comprehensive approach to help parents experiencing this condition. In conclusion, the proposal to include this disorder within the parental perinatal affective disorders, as proposed by the author Baldoni,3 given the level of overlap that it usually has with other comorbid conditions (anxiety, alcohol abuse, impulse control disorders) and high frequency of masked symptoms, goes in the direction to give the attention it deserves for early detection and provide adequate support and treatment.

Changes in paternal perinatal depression and its predictors from third trimester of pregnancy to one-year post-partum: a longitudinal study

Introduction: Paternal depression is not as widely recognized as maternal depression. Studies in Japan have examined the factors associated with paternal depression, but these have been limited to specific regions rather than conducted on a nationwide scale. This study aimed to examine changes in paternal perinatal depression from the last trimester of pregnancy to one year postpartum. Additionally, we explored the relationship between paternal perinatal depression and fathers' feelings toward their infants. Methods: This study used a longitudinal design. We initially planned to collect data from over 384 cases based on sample size calculations, and successfully collected data from 494 men in the first survey. However, more than half of the participants dropped out in the second and subsequent surveys, resulting in 201 men completing the longitudinal survey over a one-year period. Results: The mean Edinburgh Postnatal Depression Scale, Japanese version (EPDS-J) score in the last trimester of pregnancy was 9.274 (95% confidence interval [CI] 8.413-10.134), which was the highest throughout the study period. The mean EPDS-J score was lowest at 3-5 months postpartum, with a score of 7.682 (95% CI 6.816-8.547). At all time points, occupational stress and partner relationships were associated with EPDS-J scores. Conclusions: Reducing paternal perinatal depression requires controlling for occupational stress and maintaining good marital relationships. The findings suggest that addressing work-life balance is crucial for Japanese fathers to enhance their whole-family well-being. Keywords: fathers, marital relationship, occupational stress, perinatal depression

Awareness, Knowledge and Attitudes of the Brussels and Flemish-Brabant Population towards Paternal Perinatal Depression in Belgium

Introduction: Paternal perinatal depression (PPND) occurs in 10% of fathers, which implies an important burden for families and public health services. A better understanding of the population awareness on the topic is essential to adequately identify and adequately support these cases.
 Objective: This study aims to investigate the awareness, knowledge, and attitudes of the Brussels and Flemish-Brabant population in Belgium towards PPND, using the validated Depression in Dads (DDads) questionnaire.
 Methods: A two-strands descriptive study was conducted in the Brussels’ Capital Region and in the province of Flemish Brabant, Belgium between March-May 2020 and March-May 2021. The sample included 314 adults, aged 18-65 years, Flemish speaking, and living in the previously cited provinces. The DDads Questionnaire was administered online via LimeSurvey© (an encrypted and secured online data collection service) due to the COVID-19 social distancing measures. Data were analysed using IBM SPSS 28.0 SPSS© Statistics for Windows©. Ethical approval was obtained from the Brussels’ University Hospital and the Vrije Universiteit Brussel (VUB) committees.
 Results: In the case of respondents, anxiousness was the most frequently cited mental health problem as experienced by men during their partners’ pregnancy (82.4%) and during the postnatal period (68.4%). Although well recognized as mental health issue, and as a general health concern, paternal depression had low recognition by respondents, and it was considered by 37.3% of them as being “normal” during the process of fatherhood. New personality traits such as (withdrawal, avoidance, isolation, indecision, or irritability, amongst others) were regarded as a common symptom of PPND by 64.6% of respondents. When asked about best ways of coping -in the case of paternal depression- non-pharmacological approaches were mostly preferred. In the case of experiencing PPND, the main advice was to ask for support from informal networks (family or friends) whilst professional support from the mental health services was suggested only as a secondary option. Over 70% of respondents believed that paternal depression requires from a specialized treatment though. Only 39.2% of the respondents agreed that all men should be screened for depression symptoms during pregnancy, and 43.0% of participants agreed that those symptoms should also be checked after delivery.
 Conclusion: Attitudes towards PPND appeared to be diverse. PPND and perinatal mental health terms seem to be poorly understood. A clear need to increase awareness concerning men’s mental health during pregnancy (of their partners) and PPND is patent. Better awareness may help fathers in difficulty to be identified earlier, for them to be better attended during this process, and to decrease PPND rates and ultimately improve perinatal mental health. 

Understanding the Barriers Fathers Face to Seeking Help for Paternal Perinatal Depression: Comparing Fathers to Men Outside the Perinatal Period.

Research has shown that men are less likely than women to seek help for depression at any time of life due to barriers, including stereotypical masculine norms and stigma. The evidence suggests that approximately 10% of fathers experience postnatal depression, yet new and expectant fathers are not routinely offered screening or support in the same way as mothers. Therefore, this research explored the barriers fathers face to seeking help for paternal perinatal depression (PPD). Data were collected using an online survey. Initially, fathers with postnatal depression were compared to men experiencing depression at another time of their life in terms of their attitudes to seeking psychological help, conformity to masculine norms, self-stigma, and awareness of services. Secondly, a proposed model of help-seeking amongst fathers with postnatal depression was evaluated. Finally, additional barriers to help-seeking for paternal postnatal depression were explored qualitatively. A total of 125 participants took part in the quantitative comparison, and 50 of the fathers also provided qualitative data. No between-group differences were found, suggesting that the existing literature on barriers to seeking help for male depression is applicable to fathers with postnatal depression. The qualitative results also highlighted the need for better awareness of paternal postnatal depression and better access to services for fathers. Limitations, implications for policy, and directions for future research are discussed.

Revealing the hidden impact: Exploring the influence of paternal perinatal depression on father-infant bonding and strategies for enhanced support

This paper examines the significance of Paternal Perinatal Depression (PPND) during the perinatal period, highlighting its impact on newborn infants. It discusses factors contributing to PPND, including labor and societal expectations, and the interconnectedness of maternal depression. Furthermore, it explores the consequences of paternal stress on infant bonding and long-term child development.Empowering fathers is a central theme, with strategies proposed to raise awareness, screen for PPND, promote communication and provide support. Involving both parents in perinatal education and offering tailored treatment options for fathers are recommended to strengthen family dynamics and mitigate long-term consequences. Recognizing and addressing fathers' mental health needs are crucial for overall family well-being. Further research and evidence-based programs are essential to support this endeavor.

Risk factors of paternal perinatal depression during the COVID-19 pandemic in Japan

Purpose The study aims to investigate risk factors of paternal perinatal depression during the COVID-19 pandemic. Methods We conducted an online cross-sectional study of 473 prenatal fathers and 1246 postnatal fathers in August 2021. We applied a modified Poisson regression to estimate relative risk ratios of possible factors for paternal perinatal depression (measured by Edinburgh Postnatal Depression Scale), sequentially introducing the following factors into the model: individual factors, interpersonal factors, obstetric/pediatric factors, and service utilization factors. Results Prenatal fathers with the following risk factors were at an increased risk for having depressive symptoms: adverse childhood experiences (risk ratio; RR 1.61), past depression (RR 1.63), fear of COVID-19 (RR 2.09), lower social support (RR 1.91), low family resources (RR 1.95), and intimate partner violence (IPV) victimization (RR 1.29). Postnatal fathers having the following risk factors were at an increased risk for having depressive symptoms: past depression (RR 1.67), fear of COVID-19 (RR 1.26), low family resources (RR 1.85), IPV victimization. (RR 1.18), and preterm birth (RR 1.18). Conclusion The study showed risk factors such as past history of depression, high fear of COVID-19, low family functionality, and IPV victimization were associated with perinatal depressive symptoms. The findings should contribute to future directions of interventions for paternal perinatal mental health.

Association of maternal and paternal perinatal depression and anxiety with infant development: A longitudinal study

BackgroundMaternal and paternal perinatal depression and anxiety are theorised to adversely impact infant development. Yet, few studies have assessed both mental health symptoms and clinical diagnoses within the one study. Moreover, research on fathers is limited. This study therefore aimed to examine the association between symptoms and diagnoses of maternal and paternal perinatal depression and anxiety with infant development. MethodData were from the Triple B Pregnancy Cohort Study. Participants included 1539 mothers and 793 partners. Depressive and anxiety symptoms were assessed using the Edinburgh Postnatal Depression Scale and Depression Anxiety Stress Scales. Major depressive disorder, generalized anxiety disorder, social anxiety disorder, panic disorder, and agoraphobia were assessed using the Composite International Diagnostic Interview in trimester three. Infant development was assessed at 12-months using the Bayley Scales of Infant and Toddler Development. ResultsAntepartum, maternal depressive and anxiety symptoms were associated with poorer infant social-emotional (d = −0.11, p = .025) and language development (d = −0.16, p = .001). At 8-weeks postpartum, maternal anxiety symptoms were associated with poorer overall development (d = −0.11, p = .030). No association was observed for clinical diagnoses in mothers, nor paternal depressive and anxiety symptoms or clinical diagnoses; albeit risk estimates were largely in the expected direction of adverse effects on infant development. ConclusionsEvidence suggests that maternal perinatal depression and anxiety symptoms may adversely impact infant development. Effects were small but findings underscore the importance of prevention, early screening and intervention, alongside consideration of other risk factors during early critical periods.

Paternal perinatal depression: A concept analysis.

Our aim is to clarify the concept of paternal perinatal depression including its definition, attributes, antecedents and consequences. A concept analysis. To obtain relevant evidence, several databases were searched systematically including PubMed, EMBASE, Web of Science, CINAHL, PsycINFO and the Cochrane Library. Qualitative or quantitative articles published in English that focused on paternal perinatal depression were included. After the literature quality assessment, Walker and Avant's concept analysis strategy was used. Five defining attributes (i.e. symptoms occur during the partner's pregnancy or 1-year postpartum and last at least 2 weeks, emotional symptoms, somatic symptoms, negative parenting behaviours and 'masked' symptoms), four antecedents (i.e. personal issues, pregnancy-related issues, infant-related issues, social issues) and three consequences (i.e. offspring outcomes, marital relationship, maternal negative emotions) were identified.

Preventive interventions for paternal perinatal depression: a scoping review protocol

IntroductionThe objective of this scoping review is to map the literature describing preventive interventions for paternal perinatal depression. Depression is a common mental disorder experienced by fathers as well as...

Development and validation of the Japanese version of EPDS-P for indirect screening of paternal perinatal depression based on maternal reporting: Protocol for a prospective longitudinal observational study.

The main purpose of this study is to develop an indirect screening system for paternal perinatal depression based on the female partner's assessment in the Japanese population. The Japanese version of the Edinburgh Postnatal Depression Scale-Partner (EPDS-P) will be used as the indirect screening tool, and its accuracy will be studied in this longitudinal prospective observational study. Public health nurses and midwives at the participating community health center are currently inviting couples to participate, and are distributing self-rating scales to the participants. The primary evaluation scales being used in this study are the Japanese versions of the Center for Epidemiologic Studies Depression Scale (CES-D) and the Japanese version of the EPDS-P which evaluates paternal perinatal depression by women. We will evaluate EPDS-P performance against CES-D, including accuracy, sensitivity, specificity, and correlations. Perinatal depression is a mental illness that occurs between pregnancy and postpartum within the 12months, and it is known to increase the risk of adversely impacting on child development. Men may also experience a psychosocial crisis during their partners' perinatal period. Although it was recently reported that the EPDS-P can indirectly detect paternal perinatal depression, there is, as yet, insufficient evidence of this because the previous studies had relatively small sample sizes and were limited to cross-sectional studies in the postpartum period. The development of a screening system for paternal perinatal depression using the EPDS-P will lead to increased awareness of the disease and provide an opportunity to establish a family-based support system in Japan.

Psychosocial Factors Among Paternal Perinatal Depression and Anxiety: A Scoping Review

Introduction- The perinatal period, which includes pregnancy and the postpartum period, has long been linked to mother mental health issues. Emerging research, however, has provided light on the incidence of prenatal depression and anxiety among fathers. The purpose of this review is to throw light on a critical but frequently ignored part of family mental health by investigating the psychosocial variables that contribute to father prenatal depression and anxiety. Objective- To identify the psychosocial factors of paternal perinatal depression and anxiety Methods- The Arksey and O’Malley framework was used to perform the scoping review. To identify scoping review papers, a search was undertaken in nine bibliographic databases and grey literature. Prisma guidelines format used in this study. Results- Search identified a total of 1579 articles with the keywords which article publish from last seven years (2015-2022). Study completed within the period of 6 months. The reviews differed in terms of objective, methodology, and reporting depth. Study identifies the social factors, psychological factors, parenting factors and factors associated with depression and anxiety. Conclusion- The study identifies there are only few studies are based on paternal perinatal depression and anxiety, most of the study based on prenatal and postnatal period. Most of the research are review papers.. No studies are examined about paternal stress, anxiety and depression, there will a study gap.

Association of adolescent and young adult depression and anxiety with perinatal mental health in fathers: Findings from an Australian longitudinal study

The current study examined associations between preconception diagnoses of major depressive disorder (MDD) and anxiety disorders in adolescence and young adulthood and perinatal depression and anxiety symptoms in early fatherhood. In an Australian community cohort study of health and development, earlier history of MDD and anxiety disorders (extending back to adolescence) were assessed retrospectively in the third trimester of pregnancy via the Composite International Diagnostic Interview. Paternal perinatal depression and anxiety were then assessed prospectively over three timepoints (third trimester of pregnancy, 8 weeks and 12 months postpartum), using established cut-points on the Edinburgh Postnatal Depression Scale and the Depression Anxiety Stress Scales (anxiety subscale). Mixed-effects regression models examined risk associations between preconception diagnoses of MDD and anxiety disorders, and perinatal depression and anxiety symptoms at each timepoint, adjusting for socio-demographic factors and concurrent maternal mental health difficulties. The odds of clinically concerning levels of paternal perinatal depression and anxiety were 6-fold and 4-fold higher, respectively, in men with a preconception history of MDD. The odds of perinatal depression were 3-fold higher in men with a preconception history of an anxiety disorder. Less evidence was found for an association between preconception diagnoses of an anxiety disorder and perinatal anxiety in fathers. Interventions aimed at improving mental health in men during adolescence and young adulthood may promote continued psychological health in men during early fatherhood.

Paternal Perinatal Depression in Modern-Day Fatherhood.

Postpartum depression in new mothers has become a widely recognized public health concern. Paternal perinatal depression (PPND) and the mental health of fathers in the perinatal period continues to receive significantly less public attention. Overall prevalence rates of up to 25% have been documented in first-time fathers. The presence of maternal depression, unsatisfactory couple relationships, and certain psychosocial and biological risk factors are associated with poor paternal bonding and increased depression risk. Depressed fathers experience excessive self-criticism, restlessness, irritability, and aggression rather than low mood. Depression in new fathers can lead to drug and alcohol abuse, food behavior disorders, and lack of impulse control. PPND leads to developmental delay, mental health disorders, and emotional or behavioral problems in the offspring. PPND may also adversely affect a child's ability to learn new information, with lasting intellectual and scholastic consequences. There currently are no official criteria to diagnose PPND, and neither are there validated screening tools available to fathers. A family-focused approach should be considered in place of the historically gender-focused mood assessment. Nontraditional interventions such as Internet communities, e-therapy, or group workshops are shown to combat a father's contextual understanding of therapy. Group therapy with integrated cognitive behavioral therapy can address masculine norms surrounding the parenting roles of fathers and can help cultivate support networks that are otherwise absent among new dads. PPND is ideally addressed by the adoption of a father-inclusive model of care that shifts the parenting paradigm and provides emotional and parenting support to men as they experience their new role as dad.

Depressive Symptoms in Expecting Fathers: Is Paternal Perinatal Depression a Valid Concept? A Systematic Review of Evidence.

Background. Since the identification of Couvade syndrome in the late 1950s, little attention has been dedicated to the issue of depression in expecting fathers. Objective. To quantify the extent of depression in expecting fathers and find out if they match their pregnant partners’ depression. Methods. We conducted a PubMed and ClinicalTrials.gov search using paternal depression and all its variants as terms. We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement to include eligible studies. Results. We identified a grand total of 1443 articles, of which 204 were eligible. The total number of fathers/expecting fathers involved was 849,913. Longitudinal studies represented more than half of the included studies; more than three-quarters of the studies used the Edinburgh Postnatal Depression Scale (EPDS). The average occurrence of paternal depression was around 5%, which confers the entity some clinical dignity. Depression tends to occur more in expecting women and new mothers than in expecting partners or new fathers, while the co-occurrence in the same couple is quite low. Limitations. The methodological heterogeneity of the included studies prevents us from meta-analyzing the obtained data. The validity of the instruments used is another issue. Conclusions. Paternal depression is distinct from maternal depression and occurs at lower rates (about half). The very existence of a paternal depression clinical entity is beyond any doubt. Future research should address methodological heterogeneity.

Fathers' experience of depression during the perinatal period: a qualitative systematic review.

The objective of this review was to understand fathers' experiences of depression in the perinatal period, including how they recognize their depression, the emotions they experience, the impact of depression on their relationships, and their help-seeking behaviors and support. Whilst the prevalence of perinatal depression in men is now estimated to be just below that in women, no current care pathways exclusively for affected men exist in the United Kingdom. However, evidence demonstrates that paternal depression has severe consequences, affecting men's relationships with their partners and infants, their parenting behaviors, and the well-being of their children. This demonstrates a need to focus on the paternal experience of depression during this stage of life. This review included qualitative studies that included biological fathers over the age of 18 years. The phenomenon of interest was depression or mental distress in fathers within the context of the perinatal period. All qualitative designs were included in the study with a focus on lived experiences of fathers. Searches for existing systematic reviews were carried out in March 2021 and no similar protocols or completed reviews were identified. Seven databases were searched in August 2021: MEDLINE, CINAHL, PsycINFO, Scopus, ProQuest Sociology, ProQuest Dissertations and Thesis Global, and OpenGrey. Search limits included English language and Organisation for Economic Co-operation and Development (OECD) countries. Two reviewers assessed methodological quality. A standardized data extraction tool was used to extract and synthesize data. Confidence in the findings was subsequently assessed. Nine studies were included after full-text review that were considered relevant to the research questions and that focused on fathers' experiences (n = 138), although only two focused specifically on depression. The overall quality of the studies was moderate. Overall, 109 findings were collated into 22 categories producing six synthesized findings. These were mental health literacy around paternal perinatal depression is poor among men; relationships are experienced as both comforting and distressing in the perinatal period; fathers in the perinatal period do experience depression, but this is avoided, normalized, or hidden; fathers feel judged about mental health difficulties and so are reluctant to disclose them; help-seeking in fathers is prevented by non-targeted support for fathers; and all men have the potential to struggle because fatherhood is challenging. The review found that fathers may experience depression and negative emotions around the time their child is born, including anger, irritability, and resentment of the child. Men found their relationship changes difficult, feeling that fatherhood did not seem real until the baby was born. There was a significant lack of father-focused support for men, who were aware of stigma and social expectations of them. Men were not eager to seek help for their feelings, in part due to prioritizing the needs of the mother (and child) as more important. There is a need for greater attention on paternal perinatal depression through research and practice. PROSPERO CRD42021245894.

Depressive Symptoms in Fathers during the First Postpartum Year: The Influence of Severity of Preterm Birth, Parenting Stress and Partners' Depression.

Although preterm birth constitutes a risk factor for postpartum depressive symptomatology, perinatal depression (PND) has not been investigated extensively in fathers of very low (VLBW) and extremely low birth weight (ELBW) infants. This study explored paternal depression levels at 3, 9, and 12 months of infant corrected age, investigating also the predictive role played by the severity of prematurity, maternal and paternal PND levels, and parenting stress. We recruited 153 fathers of 33 ELBW, 42 VLBW, and 78 full-term (FT) infants, respectively. Depression was investigated by the Edinburgh Postnatal Depression Scale (EPDS) and distress by the Parenting Stress Index-Short Form-PSI-SF (Total and subscales: Parental Distress, Parent–Child Dysfunctional Interaction, and Difficult Child). ELBW fathers showed a significant decrease (improvement) in EPDS, total PSI-SF, and Parental Distress mean scores after 3 months. Paternal EPDS scores at 12 months were significantly predicted by VLBW and FT infants’ birth weight categories, fathers’ EPDS scores at 3 and 9 months, Parent–Child Dysfunctional Interaction subscale at 3 months, and Difficult Child subscale at 9 months. This study strengthens the relevance of including early routine screening and parenting support for fathers in perinatal health services, with particular attention to fathers who might be more vulnerable to mental health difficulties due to severely preterm birth.

“Dad is feeling blue”: what to know about paternal perinatal depression

IntroductionThe transition into parenthood is associated with an increased psychopathological vulnerability. Most studies have focused on mothers, although recently, the role of fathers has grown more importance. Paternal perinatal depression (PPD) is an episode of major depressive disorder occurring in new or expectant fathers during the perinatal period. PPD is not widely acknowledged and research are rare.ObjectivesThe authors intend to review the literature about PPD, focusing on its prevalence, risk factors, clinical features, treatment and consequences.MethodsNon-systematic review of the literature through PubMed.ResultsA meta-analysis of PPD estimated a prevalence of 10.4%. Risk factors of PPD are multiple and complex. There are sociodemographic factors, such as marital status, monthly income and social support. Psychological factors, for instance history of depression, maternal prenatal anxiety and maternal depression. Some literature also suggests hormonal changes on men like increase estrogen and lower testosterone levels. PPD can present with symptoms of mood alterations, like irritability and restricted emotions, anxiety, fatigue, insomnia, loss of appetite. Also common are behavioural disturbances such as interpersonal conflicts, impulsivity, violence, avoidance behaviour, and substance abuse. There are no studies to specific treatments to PPD, so the treatment is the same for women, such as antidepressants and psychotherapy. If untreated, PPD can have an adverse influence on the health and wellbeing of the mother and child.ConclusionsPPD is still underscreened, underdiagnosed and undertreated. It is fundamental identifying risk factors and the development of specific interventions. Further research on PPD is needed.DisclosureNo significant relationships.

Interventions for Perinatal Depression and Anxiety in Fathers: A Mini-Review.

Background and ObjectivesUp to 10% of fathers experience perinatal depression, often accompanied by anxiety, with a detrimental impact on the emotional and behavioural development of infants. Yet, few evidence-based interventions specifically for paternal perinatal depression or anxiety exist, and few depressed or anxious fathers engage with support. This mini-review aims to build on the evidence base set by other recent systematic reviews by synthesising more recently available studies on interventions for paternal perinatal depression and anxiety. Secondarily, we also aimed to identify useful information on key implementation strategies, if any, that increase the engagement of men.MethodsWe drew upon three major previous systematic reviews and performed an updated search of PubMed/Medline; Psycinfo; Cochrane Database; Embase and Cinahl. The search was limited to trials, feasibility studies or pilot studies of interventions published between 2015 and 2020 that reported on fathers' perinatal mental health. We included psychological, educational, psychosocial, paternal, couple-focused, or group therapies, delivered face-to-face, via telephone and/or online that reported on either paternal depression, anxiety or both.ResultsEleven studies satisfied search criteria (5 of which were not included in previous reviews). The majority were randomised controlled trials. Most interventions incorporated counselling, therapy or psychoeducation and took an indirect approach to perinatal mental health through antenatal or postnatal education and were couple-focused. No studies reported a presence of diagnosed depression or anxiety at baseline, although five studies reported a positive effect on sub-threshold symptoms.DiscussionThere was some evidence that these approaches may be useful in the initial engagement of fathers with perinatal supports and improve depression and anxiety scores. No studies targeted the explicit treatment of clinically depressed or anxious men, and this remains the most substantial gap in the peer-reviewed evidence base. Our results highlight the need to deliver perinatal interventions specifically designed for men and evaluate them in populations with clinical levels of depressive and anxious symptomatology.

A pilot study of multilevel analysis of BDNF in paternal and maternal perinatal depression

Depression in the perinatal period is common in mothers worldwide. Emerging research indicates that fathers are also at risk of developing perinatal depression. However, knowledge regarding biological risk factors and pathophysiological mechanisms of perinatal depression is still scarce, particularly in fathers. It has been suggested that the neurotrophin BDNF may play a role in maternal perinatal depression; however, there is currently no data regarding paternal perinatal depression. For this pilot study, 81 expecting parents were recruited and assessed at several time points. We screened for depression using EPDS and MADRS, investigated several psychosocial variables, and took blood samples for BDNF val66met genotyping, epigenetic, and protein analysis. Between pregnancy and 12 months postpartum (pp), we found that 3.7 to 15.7% of fathers screened positive for depression, and 9.6 to 24% of mothers, with at least a twofold increased prevalence in both parents using MADRS compared with EPDS. We also identified several psychosocial factors associated with perinatal depression in both parents. The data revealed a trend that lower BDNF levels correlated with maternal depressive symptoms at 3 months pp. In the fathers, no significant correlations between BDNF and perinatal depression were found. Pregnant women demonstrated lower BDNF methylation and BDNF protein expression compared with men; however, these were found to increase postpartum. Lastly, we identified correlations between depressive symptoms and psychosocial/neurobiological factors. The data suggest that BDNF may play a role in maternal perinatal depression, but not paternal.