PurposeTo assess the association between past 30-day cigarette smoking, nicotine use with an e-product device (e.g., vape), cannabis smoking, cannabis use with an e-product device, and other forms of cannabis use and past-year respiratory symptoms in a nationally representative sample of people aged 12 and older in the U.S. during 2021. MethodsData from Wave 6 (2021) of the Population Assessment of Tobacco and Health (PATH) Study was used, a national probability sample of adolescents (ages 12-17; n=5,652) and adults (ages ≥18; n=30,516). Logistic regression was used to assess the association of past 30-day cigarette smoking, nicotine use with an e-product, cannabis smoking, cannabis use with an e-product, and other forms of cannabis use with past-year respiratory symptoms (a past-year respiratory symptom index was constructed and ranged 0-9; an index of 2+ was flagged as having functionally important respiratory impairment). ResultsThe odds of a past-year respiratory index score of 2+ was greater among respondents who indicated either past 30-day cigarette or cannabis smoking compared to respondents who did not use any nicotine or cannabis during the past 30 days. Past 30-day nicotine and cannabis use with an e-product device was not associated with a respiratory symptom index of 2+. The combination of past 30-day cigarette smoking and cannabis smoking had one of the strongest associations with experiencing a respiratory index score of 2+ among dual users of nicotine and cannabis. ConclusionsPast 30-day cigarette smoking and cannabis smoking was associated with higher odds of functionally important respiratory impairment. Additionally, this study provides robust evidence regarding the potential respiratory harms of single or dual nicotine and cannabis smoking as it relates to respiratory health.
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