Part Of Practice Research Articles

Design of a Supercapacitor Module and Control Algorithm for Practical Verification of a Hybrid Energy Storage System

This paper presents an approach to designing a supercapacitor (SC) module according to defined power profiles and providing a control algorithm for sharing the energy from the SC module and accumulator in a hybrid energy storage system (HESS). This paper also presents a view of a printed circuit board (PCB) of the SC module and an interconnection board between the bidirectional converter, accumulator, and SC module. The practical part of the paper presents the measurement of the voltages and currents on the SC module, accumulator, and output of the DC/DC converter to visualize the energy flow between them.

Factors that support teachers as educational professionals doing doctoral studies: an integrative literature review

In recent decades, various initiatives have been established to support the professional development of teachers and their school context. In some cases, they provide teachers the opportunity to combine their profession with doctoral studies. This paper explores factors that support teacher research as part of school practice and academia. It takes the perspective of teachers as a starting point and examines their experiences through the lens of the learning potential of boundaries. A review of empirical studies was conducted from various international educational contexts through an integrative literature review. The selected empirical studies (n = 13) contributed to a better understanding of the complexity of this undertaking, and three themes were generated as main factors: (1) a stimulating school culture; (2) engaging with the academic community; (3) and aligning the research design with the practitioners’ needs.

The phenomenon of word-creation as a kind of language game (on the example of the online dictionary Slovodna)

This study aims to investigate the implementation of the phenomenon of word creation as a kind of а language game in the modern media space – the social network Instagram.The theoretical part of the study is based on several works devoted to the phenomenon under study by Boris Norman, Vladimir Sannikov, Tatiana Kuranova, and Lidia Malygina.The basis of the practical part of the article was the analysis of examples from the Internet dictionary SlovoDna, aimed at comparing language game techniques with their direct implementation in the modern Russian language.Current work uses methods such as introspection and reconstruction of the internal form of wordplay and their word-forming analysis. As a result of the research, nonce words are singled out into several subgroups based on the method of formation (reception); the main functions of the word-formation language game implemented by the authors of the Internet dictionary while creating words are determined; conclusions about the linguistic experiments of SlovoDna are made.

Treatment satisfaction and effectiveness of Lurasidone on quality of life and functioning in adult patients with schizophrenia in the real-world Italian clinical practice: a prospective 3-month observational study.

Although second-generation antipsychotics (SGAs) have proven to be effective therapeutic options for patients with schizophrenia, there is a notable lack of evidence on patients' subjective perspectives regarding their well-being, quality of life, and satisfaction with these medications. This study aimed to evaluate the treatment satisfaction and effectiveness of lurasidone on quality of life and functioning in adult patients with schizophrenia in real-world Italian clinical practice. This was a multicentre, national, non-interventional, single-arm, 3-month prospective study. Patients who were naive to lurasidone treatment and whose treating physician had decided to start them on this medication were enrolled and evaluated over a 3-month period. Eligible patients were adults (≥ 18 years of age) with a primary diagnosis of schizophrenia who were being treated with lurasidone (for the first time [i.e., they were lurasidone naive]) as part of routine clinical practice. Efficacy endpoints were changes in patient/caregiver treatment satisfaction (seven-point Likert scale from the Treatment Satisfaction Questionnaire for Medication), patient quality of life and functioning (QLS), investigator-rated global assessment of functioning (CGI-S, IAQ) after 6 weeks and 3 months of lurasidone, and number of relapses and hospitalizations. Sixty-one patients were enrolled and 59 completed the study. The median dosage of lurasidone at baseline was 37.00mg/day. The median duration of titration was 86.0 days (Min 28; Max 115 days); the median number of dosage changes was 1.0. At the end of 3-month observation period, the median dose of lurasidone was 74.00mg/day. QoL and Functioning Score showed a trend of improvement over time, reaching a mean change from baseline of 9.8 at the end of the study. According to the CGI-S, the percentage of patients who were "markedly or severely ill" showed a continuous decrease from baseline to 3 months, from 62.29% to 8.20%. Patient satisfaction increased over time, with 80.32% of patients reporting that they were somewhat, fairly, or very satisfied (including 63.93% who were completely or very satisfied) at the end of the study. No relapses/hospitalizations for psychiatric reasons were reported. Lurasidone was well tolerated with no safety concerns or discontinuations due to AEs. Lurasidone represents a valid option for the treatment of schizophrenia and positively affects subjective well-being, quality of life and satisfaction. NCT06527885 retrospectively registered (01/08/2024).

Communities of Practice Support Implementation of Power to Kids in Residential Care: The EMBED Model

ABSTRACTChildren and young people in residential care continue to experience significant harmful sexual behaviour, dating violence and child sexual exploitation. Power to Kids is a programme developed in Australia to prevent and respond to these forms of abuse for this cohort. The aim of the study was to explore how a Communities of Practice initiative could further support the implementation of the Power to Kids programme in the residential care practice of a community service organisation. Qualitative data were collected through feedback loops (n = 12) with residential carers and senior staff and focus groups (n = 4). Quantitative data were collected through two surveys (n = 89) and (n = 46). The data revealed inductively the EMBED model: Executive commitment to Communities of Practice, Members of Communities of Practice engage with content, Becoming part of everyday practice, Enhanced knowledge of sexual health and safety and Decline in going missing and better relationships. Findings suggest that a Community of Practice approach to implementing Power to Kids is promising in embedding the sexual health and safety programme.

Naturally Occurring Compounds Targeting Peroxisome Proliferator Receptors: Potential Molecular Mechanisms and Future Perspectives for Promoting Human Health

Background: Peroxisome-proliferator-activated receptors (PPARs) constitute nuclear transcription factors controlling gene expression associated with cell growth and proliferation, diverse proteins, lipids, and glucose metabolism, being related to several other pathophysiological states such as metabolic disorders, atherogenesis, carcinogenesis, etc. The present survey aims to analyze the natural compounds that can act as agonists for the PPAR-α, PPAR-β/δ, and PPAR-γ system targeting, highlighting how the amazing biochemical diversity of natural compounds can yield new insights into this “hotspot” of the scientific field. Methods: A narrative review was performed by searching the recent international literature for the last two decades in the most authoritative scientific databases, like PubMed, Scopus, Web of Science, and Embase, using appropriate keywords. Results: Several natural compounds and/or their synthetic derivatives can act as ligands of PPARs, stimulating their transcriptional activity and enabling their use as preventive and/or therapeutic agents for several disease states, such as inflammation, oxidative stress, metabolic disturbances, atherogenesis, and carcinogenesis. Although synthetic compounds are increasingly used as drugs to manage health problems, serious side effects have been observed, while their natural analogues exhibit only few minor side effects. Conclusions: Further clinical studies on natural compounds such as ligands of PPARs and the evaluation of the related molecular mechanisms are needed to implement an effective strategy concerning the pharmaco-technology, food chemistry, and nutrition to introduce them as part of clinical and dietary practice.

Pelayanan Pengaduan Masyarakat Peduli Lingkungan Pada Dinas Lingkungan Hidup Kota Palangka Raya

<em>Palangka Raya City, as the center of government and economic growth in Central Kalimantan, faces serious challenges in waste management. The increasing amount of waste generated by community and industrial activities demands attention and concrete action to maintain cleanliness and environmental sustainability. This community service activity aims to raise public awareness about the importance of proper waste management and to provide facilities for reporting and handling waste. The activities include socialization and counseling about the types of waste, the negative impacts of waste on health and the environment, as well as effective reporting procedures. By providing easily accessible reporting facilities, such as hotlines and mobile applications, it is hoped that the community can play an active role in reporting waste issues they encounter. The expected outcomes of this activity are increased public awareness, an increase in the number of waste reports, and more effective waste management, which in turn will contribute to a cleaner and healthier environment in Palangka Raya City. This community service activity is implemented as part of the Field Work Practice (PKL) of the Integrated School of Management Informatics & Computer (STMIK). This activity is expected to create a culture of shared responsibility in environmental management and support the sustainability efforts initiated by the local government.</em>

Within-couple comparison of maternal and paternal distress in an Italian birth cohort

ObjectiveThis study compared parental distress in 166 couples, using the Parenting Stress Index–Short Form (PSI-SF), in the Italian NASCITA cohort at the two-year well-child visits. The study explored the concordance of distress levels within couples (aim 1) and their correlation with child-related stressors (aim 2).BackgroundPrevious studies focused on maternal distress or considered maternal and paternal experiences separately, without addressing differences within couples.MethodData on parental distress were collected from the PSI-SF completed separately by parents. The total score was derived from three subscales, with high distress defined by a score above 85. The Wilcoxon signed-rank test compared the total PSI-SF scores of mothers and fathers. The prevalence of high distress was assessed using chi-square tests, and concordance between parents within the same couple was estimated using Cohen’s K statistic. Chi-square tests were also used to compare distress levels in parents exposed to potential child-related stressors versus those not exposed.ResultsA slightly higher total score (z = -2.45; p = 0.01) was observed in mothers versus fathers, although the prevalence of distress was similar (15.1% vs. 13.9%, respectively; p = 0.76). Nine children (5.4%) had both parents distressed. Agreement in the high level of distress was observed for 81.9% of the couples, with a fair agreement on the total score (Cohen’s K = 0.27).The percentage of children with both distressed parents was slightly higher in the group exposed to potential stressors (6.6% vs. 4%, p = 0.49).ConclusionsIt is essential to evaluate distress in parents exposed to potential stressors related to child characteristics early. This assessment should be part of the pediatric family practice to prevent adverse outcomes in both child and parental wellbeing.

‘Making vulnerability’ while negotiating family care practices: evidence from multigenerational living

ABSTRACT The article draws upon in-depth interviews conducted in Czech multigenerational living with representatives of three generations. The repeated interviews took place in 2018–2019 and then in spring 2020 during the Covid-19 pandemic. The analysis focused on caring practices and dynamics of care between three generations and how these had been impacted by pandemic in 2020. We were interested in how the pandemic affected the daily lives of multigenerationally living family members and how through their caring practices they redefine what family in the era of super-diversity is. In order to do so, we particularly focus on how vulnerability has been constructed through the caring practices as a response to Covid-19. We followed the scholarship on vulnerability which emphasises its social character and sees it as a social construct. We put forward this discussion and aim at developing the concept of ‘making vulnerability’ – processes through which people make themselves and others vulnerable through daily taken-for-granted routines and rituals – as an essential part of family care practices.

Can Knowledge Management Be Appropriate for Shipbuilding?: Based on Typology and the Seven C’s Model

I use typology to find the divisions of knowledge management by literature review, then I use the seven C's model to evaluate knowledge management in shipbuilding. The research aims to promote the knowledge management practice in shipbuilding. In the meantime, the research method can be a reference for future research on knowledge management in other fields. From the evaluation of the seven C’s model, we can see that six aspects of the implementation of knowledge management are suitable for shipbuilding. But in the connection part, we realize that if we want to keep a strong connection with all the people in shipbuilding, it is very difficult. The limitation of our research is that we rely on the literature review and our own experience to evaluate. It will be meaningful to conduct empirical research in the future to fill up the gap between the academic part and the practice part. This article can help shipbuilding organizations realize that conducting knowledge management is appropriate for shipbuilding. In the meantime, it reminds us what we need to do if we want to have effective knowledge management in shipbuilding.

Comparison of Physiological Stress Indices in Anesthetized and Manually Restrained Leopard Sharks, Triakis semifasciata

Background: Leopard sharks (Triakis semifasciata) are abundant, coastal, eastern Pacific, mesopredatory sharks and are frequently managed in aquariums and zoos. Medical examinations are a routine part of good husbandry practices, but the handling protocols vary greatly between facilities. In this study, we compared the physiological stress responses of T. semifasciata associated with manual restraint and sedated handling under parallel holding and handling procedures in a 10 min interval. Methods: Blood was collected and analyzed for the hematocrit (Hct), lactate, glucose, beta-hydroxybutyrate (β-HB), pH, blood gasses, 1α-hydroxycorticosterone (1α-OHB), and corticosterone (B). Results: Overall, a minimal physiological stress response was observed in both groups. However, statistically significant increases in the PCO2, β-HB and lactate occurred, while the pHTC, SO2, and BE decreased over time in the manual-restraint group. In the sedated group, the B, PCO2, and lactate increased while the pHTC, SO2, and base excess (BE) decreased over time. When comparing treatments, the sedated group had a higher B and PCO2 TC and a lower pHTC, BE, and SO2 than the manual-restraint group at the second time point. Conclusions: This study indicates that manual restraint is comparable to the described sedation in T. semifasciata for minimally invasive procedures. The overall results show that this species had low physiological stress responses to both methods.

Revisiting the conceptualisation and implications of medicine's 'hidden curriculum'.

In medical training and practice, our professional attributes, attitudes, perceptions, character traits and identities are fundamentally shaped by our lived experiences and observations in clinical and para-clinical settings instead of being inculcated through formal curriculum or classroom teaching. For instance, clinical acumen, communication skills and bedside manners are learnt through role modelling and experiential learning in the course of clinical rotations. Likewise, one's attitudes, professional behaviours and inclinations are often also influenced by direct/indirect observations of the actions of others in the medical fraternity in various clinical and non-clinical settings. This is also what is often termed as the 'hidden curriculum' of medicine. In this article, we sought to provide a practical conceptualisation of the hidden curriculum in medical training, which we describe as lived experiences and personal observations of medical trainees and residents in clinical and para-clinical spaces, which shape their perceptions of the medical profession (vocational identity and purpose), patients (patient-physician relationship) and colleagues (intra- and inter-professional relationships), with downstream implications on physician well-being and clinical decision-making. Although this idea of a 'hidden curriculum' has conventionally carried predominantly negative connotations in medical literature, we suggest that it is an inevitable part of medical education and practice, which, through deliberate regulation, can potentially be shaped to create more positive and meaningful effects in the professional development of medical trainees.

Continuous Blood Pressure Indices During the First 72 Hours and Functional Outcome in Patients with Spontaneous Intracerebral Hemorrhage.

Management of intracerebral hemorrhage (ICH) is challenged by limited therapeutic options and a complex relationship between blood pressure (BP) dynamics, especially BP variability (BPV) and ICH outcome. In an exploratory analysis of prospectively collected data on consecutive patients with nontraumatic ICH between 2015 and 2020, continuous BP accessed via an arterial line extracted from the Intellispace Critical Care and Anesthesia information system (Philips Healthcare) was analyzed over the first 72 h post admission. Arterial lines were used as part of standard clinical practice in the intensive care, ensuring high fidelity and real-time data essential for acute care settings. BPV was assessed through successive variation (SV), standard deviation (SD), and coefficient of variation using all available BP measurements. Multivariate regression models were applied to evaluate the association between BPV indices and functional outcome at 3 months. Among 261 patients (mean age 69.6 ± 15.2 years, 47.9% female, median National Institutes of Health Stroke Scale [NIHSS] score 6 [interquartile range 2-12]) analyzed, lower systolic BP upon admission (< 140 mm Hg) and lower systolic BPV were significantly associated with favorable outcome, whereas higher diastolic BPV correlated with improved outcomes. In the multivariate analysis, diastolic BPV (SD, SV) within the first 72 h post admission emerged as an independent predictor of good functional outcome (modified Rankin Scale score < 3; odds ratio 1.123, 95% confidence interval CI 1.008-1.184, p = 0.035), whereas systolic BPV (SD) showed a negative association. Patients with better outcomes also exhibited distinct clinical characteristics, including younger age, lower median NIHSS scores, and less prevalence of anticoagulation therapy upon admission. This study shows the prognostic value of BPV in the acute phase of ICH. Lower systolic BPV (SD) and higher diastolic BPV (SD, SV) were associated with better functional outcomes, challenging traditional BP management strategies. These findings might help to tailor a personalized BP management in ICH.

Is Sharing One’s Personal Story of Victimization Preferred? Incarcerated Women’s Perspectives on Group Treatment for Sexual Trauma

Treatment preferences are an important part of evidence-based practice and have been shown to affect treatment outcomes. In this two-part study, incarcerated women were asked about their preferences for two versions of a trauma-focused group treatment: one that requires sharing their personal memory of sexual victimization (Sharing Required) and one that does not (Sharing Not Required). Study 1 enrolled 88 non-treatment seeking women who evaluated the treatments based on descriptions of the groups. Study 2 was a partially randomized patient preference trial with 85 treatment-seeking women who either agreed to be randomly assigned to one of the two therapy groups or declined randomization and instead were directly assigned to their preferred therapy. Participants in Study 1 evaluated the Sharing Not Required condition more favorably (p &lt; 0.001, Cohen’s d = 0.39). However, the results were affected by PTSD symptom severity as those above the clinical cutoff for probable PTSD evaluated both group treatments more favorably than those below the cutoff (ps &lt; 0.05, Cohen’s ds ≥ 0.46). Study 2 found no significant difference between the proportion of participants who chose Sharing Required, Sharing Not Required, or had no personal preference, and the results did not differ by PTSD symptom severity (ps ≥ 0.70). Outcomes suggest that a variety of forms of trauma-focused therapy may be acceptable to incarcerated women, including those that involve personal narration of trauma memories and those that do not.

Cytological Characteristics of the Eye Conjunctiva in Dogs with Atopic Dermatitis

Atopic dermatitis is a chronic, pruritic inflammatory skin disease affecting approximately 10% of dogs worldwide. The disease typically manifests at an early age, causing pruritus and secondary skin lesions in specific anatomical regions. The pathophysiology of canine atopic dermatitis (CAD) remains incompletely understood, but recent research suggests a complex interplay between skin barrier dysfunction, allergic sensitisation, and microbial dysbiosis. Despite the well-established association between atopic dermatitis and conjunctivitis, the prevalence of conjunctivitis in dogs with CAD is often underestimated in clinical practice due to inadequate recognition of symptoms and a lack of specific diagnostic protocols. This study aimed to analyse the cytological characteristics of the conjunctiva in dogs affected by atopic dermatitis. Samples were collected from 24 dogs diagnosed with CAD and treated at the University Veterinary Hospital, Faculty of Veterinary Medicine, University of Zagreb. Cytological analysis was performed on samples obtained using a cytobrush. The results revealed the presence of inflammatory cells in all samples, with lymphocytes most prevalent (87.5%). A mild degree of conjunctival metaplasia was observed in all dogs, regardless of the type of inflammatory cells and the severity of conjunctivitis. These findings suggest that atopic dermatitis may induce changes in the conjunctiva that are not necessarily correlated with the intensity of the inflammatory response. The presence of lymphocytes, along with eosinophils in some cases, underscores the diagnostic value of conjunctival cytology in dogs with CAD. Furthermore, the increased density of goblet cells suggests similarities in the pathophysiology of ocular allergies in dogs and humans, opening avenues for further research to better understand and treat these conditions. This study highlights the importance of an interdisciplinary approach in the diagnosis and treatment of atopic dermatitis, including regular ophthalmologic examinations as part of standard clinical practice.

Generalized SmartScan: An Intelligent LPBF Scan Sequence Optimization Approach for Reduced Residual Stress and Distortion in 3D Part Geometries

Abstract Laser powder bed fusion (LPBF) is an additive manufacturing technique that is gaining popularity for producing metallic parts in various industries. However, parts produced by LPBF are prone to residual stress, deformation, cracks and other quality defects due to uneven temperature distribution during the LPBF process. To address this issue, in prior work, the authors have proposed SmartScan, a method for determining laser scan sequence in LPBF using an intelligent (i.e., model-based and optimization-driven) approach, rather than using heuristics, and applied it to simple 2D geometries. This paper presents a generalized SmartScan methodology that is applicable to arbitrary 3D geometries. This is achieved by: (1) expanding the thermal model and optimization approach used in SmartScan to multiple layers; (2) enabling SmartScan to process shapes with arbitrary contours and infill patterns within each layer; (3) providing the optimization in SmartScan with a balance of exploration and exploitation to make it less myopic; and (4) improving SmartScan&amp;#x92;s computational efficiency via model order reduction using singular value decomposition. Sample 3D test artifacts are simulated and printed using SmartScan in comparison with common heuristic scan sequences. Reductions of up to 92% in temperature inhomogeneity, 86% in residual stress, 24% in maximum deformation and 50% in geometric inaccuracy were observed using SmartScan. An approach for using SmartScan for printing complex 3D parts in practice, by integrating it as a plug-in to a commercial slicing software, was also demonstrated experimentally, along with its benefits in significantly improving printed part quality.

Cleaning Method Validation for Determination of Residues in Anti-Cancer Drug product for Injection by Using RP-HPLC Technique

Cleaning method validation is a part of good practices in pharmaceutical sector and need to seek the contamination present in production area. OBJECTIVE: An RP-HPLC method for the cleaning samples analysis for Anti-Cancer Drug product Melphalan Hydrochloride for Injection was develop and validated. The method was developed and validated for quantitation of Cleaning of residue left in the vessels of the production equipment’s. The analytical method used to determine the complete cleaning for Melphalan Hydrochloride for Injection by HPLC method. METHOD: The Cleaning validation was performed on Inertsil ODS,C18,(150mm×4.6mm,5μm) chromatographic column temperature at 40°C, and the detection wavelength was set at 260nm. Mobile Phase-A:10mL ammonium acetate, 88mL Purified water, 10mL acetic acid, 2mL Triethylamine, and Mobile Phase-B: 1mL Buffer, 10mL acetonitrile,190mL Purified water, and at a flow rate of 1.5 mL/min, and the injection volume was 10μL. RESULTS: The validation results of Melphalan Hydrochloride were linear over the concentration from 0.10 µg/mL to 0.75µg/mL (r = 1.00) and the recoveries from LOQ to 150% and precision ranged from 50% to 76% (RSD &lt; 30%, n =9). CONCLUSION: This method has been validated successfully and all the results met the acceptance criteria. Hence method of Cleaning Validation is suitable for testing of residue sample of Melphalan Hydrochloride for Injection.

Cluster of the e-Libraries of the Students’ Scientific Society at the University of Library Studies and Information Technologies in Sofia, Bulgaria

The information resources of the Students’ Scientific Society (SSS) at the University of Library Studies and Information Technologies (ULSIT) in Bulgaria are presented in the current article as an example of reference-information mapping. The retrospective channel of this modeling, structured in 29 e-libraries (2005–), designed for universities, libraries and civil society, was defined as an interdisciplinary cluster of the informatization in Bulgaria with wide international resonance. The methodology of development of the e-libraries and the used terminology define them as a secondary-documental resources. The semantic aspects of the е-libraries are shown as a unified system that is rooted in the universal humanitarian studies and virtually organized around the model of theoretical and practical methodological directions for organization of reference information retrieval databases. The perspectives of the development of similar information resources in the future are revealed. The creation of these e-libraries was part of a pedagogical practice through which students of Library Studies and Information Technologies learned information modeling in an open laboratory environment.

Crafting Digital Experiences: Embedding Human-Centred and Participatory Design into Archaeological Practice

As digital archaeology has grown as a field of practice, so has the number of digital resources developed for specialists and non-specialists alike. However, the creation of such outputs has not always been accompanied and informed by design theory and practices. Design – used in its broadest definition as a process of conceptual making - is an integral, if often implicit, part of archaeological practices and it is through design that we develop and share our work – from data collection and analysis to interpretation and dissemination – and engage with our stakeholders. Engaging with core design practices offers meaningful opportunities for generating new forms of archaeological knowledge production and sharing, as well as creating digitally mediated experiences that are not guided by our own assumptions about our stakeholders’ needs and can really affect people’s engagement with the past. In this paper, I investigate the benefits of embedding Human-Centred and Participatory Design into the archaeology and heritage sectors to create more critically engaged digital encounters with the past.

How to leverage implementation research for equity in global health

Implementation research (IR) is important for addressing equity in global health. However, there is limited knowledge on how to operationalize IR for health equity, and pathways for improving health equity through IR in global health settings. This paper provides an overview of guidance and frameworks for thinking about health equity as part of IR while noting the gaps in how this guidance and frameworks apply to global health. It proposes an approach to guide implementation teams in the application of IR for achieving equity in global health considering these gaps. It describes key equity considerations for different aspects of IR (i.e., implementation contexts, strategies, outcomes, and research designs). These considerations can be applied prospectively and retrospectively, and at different stages of IR. The paper further describes causal pathways, intervention levers, and strategies for achieving health equity in global health settings through IR. Central to these pathways is the power asymmetries among different actors involved in IR in global health and how these contribute to health inequities. The paper suggests recommendations and strategies for shifting the balance of power among these actors while addressing the structural and systemic determinants of health inequities as part of IR. Explicit considerations for health equity as part of implementation research and practice are needed for the achievement of global health goals. Such explicit considerations should look back as much as possible, and entail defining and analyzing health inequities and intervening on the underlying causes and mechanisms of health inequities as part of IR on a routine basis.