Particular Challenges In Terms Research Articles

AI, biometric analysis, and emerging cheating detection systems: The engineering of academic integrity?

Cheating behaviors have been construed as a continuing and somewhat vexing issue for academic institutions as they increasingly conduct educational processes online and impose metrics on instructional evaluation. Research, development, and implementation initiatives on cheating detection have gained new dimensions in the advent of artificial intelligence (AI) applications; they have also engendered special challenges in terms of their social, ethical, and cultural implications. An assortment of commercial cheating–detection systems have been injected into educational contexts with little input on the part of relevant stakeholders. This paper expands several specific cases of how systems for the detection of cheating have recently been implemented in higher education institutions in the US and UK. It investigates how such vehicles as wearable technologies, eye scanning, and keystroke capturing are being used to collect the data used for anti-cheating initiatives, often involving systems that have not gone through rigorous testing and evaluation for their validity and potential educational impacts. The paper discusses accountability- and policy-related issues concerning the outsourcing of cheating detection in institutional settings in the light of these emerging technological practices as well as student resistance against the systems involved. The cheating-detection practices can place students in a disempowered, asymmetrical position that is often at substantial variance with their cultural backgrounds.

Dielectric Loss and Electrical Conductivity Behaviors of Epoxy Composites Containing Semiconducting ZnO Varistor Particles.

Polymer nanodielectrics render a great material platform for exhibiting the intrinsic nature of incorporated particles, particularly semiconducting types, and their interfaces with the polymer matrix. Incorporating the oxide fillers with higher loading percentages (>40 vol%) encounters particular challenges in terms of dispersion, homogeneous distribution, and porosity from the process. This work investigated the dielectric loss and electrical conduction behaviors of composites containing semiconducting ZnO varistor particles of various concentrations using the epoxy impregnation method. The ZnO varistor particles increased the dielectric permittivity, loss, and electrical conductivity of the epoxy composites into three different regimes (0–50 vol%, 50–70 vol%, 70–100 vol%), particularly under an electric bias field or at higher temperatures. For lower loading fractions below 50 vol%, the dielectric responses are dominated by the insulating epoxy matrix. When loading fractions are between 50 and 70 vol%, the dielectric and electric responses are mostly associated with the semiconducting interfaces of ZnO varistor particles and ZnO–epoxy. At above 70 vol%, the apparent increase in the dielectric loss and conductivity is primarily associated with the conducting ZnO core forming the interconnected channels of electric conduction. The foam-agent-assisted ZnO varistor particle framework appears to be a better way of fabricating composites of filler loading above 80 vol%. A physical model using an equivalent capacitor, diode, and resistor in the epoxy composites was proposed to explain the different property behaviors.

Editorial: Natural-hazard risk assessment in developing countries

Developing countries are disproportionately affected by natural hazards and lack of coping capacities. 15 This combination sets back progress on poverty alleviation and slows long-term development, 16 contributing the aggravation of the many obstacles already faced by these countries and their 17 communities. Probabilistic risk assessment models are increasingly popular tools for estimating 18 potential human and economic loss due to natural hazards. Within such a context, risk modeling for 19 developing countries presents specific challenges in terms of quantity and quality of the available input 20 data at all components of risk: hazard, exposure, and vulnerability. As such, widening the types of 21 hazards and ensuring that models are contextualized to the local needs of these countries is also crucial 22 and may require innovative or, some times, simplified, yet sound, approaches that tackle the well-23 known deficiencies in this context. Some of the above-mentioned challenges include: (i)

Cardiac Implantable Electronic Devices in the Fontan Patient.

As a result of remarkable progress in operative techniques and cardiology care during childhood, Fontan patients continue to age and require team-based multidisciplinary expertise to manage complications encountered in adulthood. They face particular challenges in terms of altered hemodynamic stressors, cardiac and hepatic failure, and arrhythmias. Arrhythmias in Fontan patients are highly prevalent and associated with underlying anatomy, surgical technique, and postoperative sequelae. Diagnostic tools, treatments, and device strategies for arrhythmias in Fontan patients should be adapted to the specific anatomy, type of surgical repair, and clinical status. Great strides in our understanding of arrhythmia mechanisms, options and techniques to obtain access to relevant cardiac structures, and application of both old and new technologies have contributed to improving cardiac implantable electronic device (CIED) therapies for this unique population. In this state-of-the-art review, we discuss the various arrhythmias encountered in Fontan patients, their diagnosis, and options for treatment and prevention, with a focus on CIEDs. Throughout, access challenges particular to the Fontan circulation are considered. Recently developed technologies, such as the subcutaneous implantable cardioverter defibrillator, carry the potential to be transformative but require awareness of Fontan-specific issues. Moreover, new leadless pacing technology represents a promising strategy that may soon become applicable to Fontan patients with sinus-node dysfunction. CIEDs are essential tools in managing Fontan patients, but the complex clinical scenarios that arise in this patient population are among the most challenging for the electrophysiologist treating patients with congenital heart disease.

Spatial Regression Models for Field Trials: A Comparative Study and New Ideas.

Naturally occurring variability within a study region harbors valuable information on relationships between biological variables. Yet, spatial patterns within these study areas, e.g., in field trials, violate the assumption of independence of observations, setting particular challenges in terms of hypothesis testing, parameter estimation, feature selection, and model evaluation. We evaluate a number of spatial regression methods in a simulation study, including more realistic spatial effects than employed so far. Based on our results, we recommend generalized least squares (GLS) estimation for experimental as well as for observational setups and demonstrate how it can be incorporated into popular regression models for high-dimensional data such as regularized least squares. This new method is available in the BioConductor R-package pengls. Inclusion of a spatial error structure improves parameter estimation and predictive model performance in low-dimensional settings and also improves feature selection in high-dimensional settings by reducing “red-shift”: the preferential selection of features with spatial structure. In addition, we argue that the absence of spatial autocorrelation (SAC) in the model residuals should not be taken as a sign of a good fit, since it may result from overfitting the spatial trend. Finally, we confirm our findings in a case study on the prediction of winter wheat yield based on multispectral measurements.

Roditeljska samoprocena postupaka u vaspitnom radu s decom

The goal of our research was to examine how parents evaluate their pedagogical actions regarding their children. The research was conducted on a sample of 198 parents of children attending final grades of primary school in Eastern Serbia (Negotin, Bor, Zaječar, Kladovo, and Knjaževac). Survey method and theoretical analysis method were used in the research. The researchers developed a fivelevel Likert type scale, the Parents' Self-Evaluation of Pedagogical Actions, consisting of 30 items referring to different pedagogical actions relative to affective dimensions and control dimensions. The results show the prevalence of affective dimension in parents' self-evaluation. When it comes to parents' level of education, the results indicate that parents with college and university degrees are more in the zone of responsible parenthood than parents who finished only primary school or have high-school diplomas. The results of this research can be a special challenge in terms of including children in some future research to examine the problem of parents' pedagogical actions from both perspectives. The research findings can also be used in the context of the development of educational programmes that can be implemented through cooperation between schools and parents.

How and why? Technology and practices used by university mathematics lecturers for emergency remote teaching during the COVID-19 pandemic

The COVID-19 pandemic led to closures of university campuses around the world from March 2020 onwards. With little or no time for preparation, lecturers turned to emergency remote teaching to continue to educate their students. Online mathematics education poses particular challenges in terms of both the hardware and software necessary for effective teaching, due to issues with mathematical symbols and notation, among others. In this paper, we report upon an online survey of 257 university mathematics lecturers across 29 countries, which explores what hardware and software they used for emergency remote teaching, for what purposes they used these and what training and support were made available to them at the time. We also consider what approaches they took to emergency remote teaching and what were their reasons for this.

Challenges of Migrant Entrepreneurship in Selected Regions of Central Europe

Abstract This article addresses the migrant entrepreneurship in selected Central European regions by focusing on a general social and legislative framework, as well as migrants’ own perceptions of their challenges, needs, advantages and future prospects. It is based on the combination of secondary data and fieldwork material referring to the interviews and focus groups. The study shows that entrepreneurship is a successful strategy for effective integration into the host society. Migrant entrepreneurs are facing specific challenges in terms of understanding the legislation and the specifics of the local business environment. They often engage in niche services and production. However, they typically see themselves not as migrants but as entrepreneurs and claim to share the needs with entrepreneurs in general.

Improving Risk Assessments by Sanitary Inspection for Small Drinking-Water Supplies—Qualitative Evidence

Small drinking-water supplies face particular challenges in terms of their management. Being vulnerable to contamination but often not monitored regularly nor well-maintained, small drinking-water supplies may pose consequences for health of users. Sanitary inspection (SI) is a risk assessment tool to identify and manage observable conditions of the water supply technology or circumstances in the catchment area that may favour certain hazardous events and introduce hazards which may become a risk to health. This qualitative research aimed to identify the strengths and weaknesses of the SI tool as published by the World Health Organisation to inform a review and update of the forms and to improve their robustness. The study identified a number of benefits of the approach, such as its simplicity and ease of use. Challenges were also identified, such as potential for inconsistencies in perception of risk between inspectors, in interpreting questions, and lack of follow-up action. The authors recommend a revision of the existing SI forms to address the identified challenges and development of complementary advice on possible remedial action to address identified risk factors and on basic operations and maintenance.

Management of diet in gastrointestinal cancer.

Nutrition and gastrointestinal cancer are inextricably linked. The metabolic effects of cancer along with changes in dietary intake, the development of cancer cachexia and the presence of sarcopenia can influence changes in body composition. These have a negative impact on quality of life and tolerance to cancer treatment. Treatment for cancer presents some significant nutritional challenges as nutrition impact symptoms may develop, be exacerbated by treatment and may contribute to a worsening in nutritional status. Nutrition screening and assessment should be an integral part of holistic patient care. The provision of appropriate, evidence-based dietary advice should occur before, during and after cancer treatment. Appropriate and timely methods of nutritional support across the spectrum of gastrointestinal cancer are needed to ensure that people are adequately supported during courses of treatment that can span weeks and months. These can range from standard approaches of supplementing oral intake to complex interventions such as managing high output intestinal stomas. The gastrointestinal tract is particularly susceptible to impact from systemic anti-cancer treatments and radiotherapy. Gastrointestinal late effects of cancer treatment are now recognised to present particular challenges in terms of both medical and nutritional management. These late effects have a significant impact on the individual and their quality of life in addition to implications for the health service. Dietary intake following cancer treatment has an impact on quality of life and future research may demonstrate its influence on the risk of recurrence of gastrointestinal cancer.

Introducing Fluorescence Guided Surgery into Neuro-Oncology Practice and Getting It Right First Time

Abstract Introduction Fluorescence Guided Surgery (FGS) using 5-ALA is recommended for patients undergoing resection of suspected high grade glioma and this type of surgery is increasingly being used in more units throughout the UK. We report on our experience of introducing 5-ALA guided surgery for suspected HGG in a regional neurosciences unit. Methods Consecutive series of the first 24 patients in our unit to receive 5-ALA guided surgery for suspected HGG from June 2017 to October 2018. Data was prospectively collected. Results 5-ALA fluorescence guided surgery was used for a range of histologically confirmed WHO grade III-IV gliomas. All but 1 tumour (GBM) fluoresced with 5-ALA, with strong fluorescence in recurrent GBM and anaplastic foci of grade 3 tumours. EOR varied according to the eloquence of the lesion with 70% of cases achieving gross total resection. 40% of cases used awake mapping or intraoperative neurophysiology. 5 patients (20.8%) had temporary neurological deficits which resolved in all cases. Individual surgeon learning curves resulted in 2 styles of practice- complete FGS with fluorescence used throughout the case, and intermittent use of fluorescence as an adjunct often at the end of debulking under white light. Conclusions Adopting 5-ALA use comes with specific challenges in terms of service organisation, learning curves and complication avoidance. Our experience is that it is useful both to improve EOR and as an adjunct to identify tumour tissue in eloquent region tumours with monitoring of function. This is possible through a day admission pathway in line with GIRFT.

Teachers’ perceptions of preparing “good citizens” for the democratic development: Hong Kong case

ABSTRACT Universal suffrage is an essential component of Western democracy in the twenty-first century, but the role of education in supporting universal suffrage in Hong Kong is a challenge given its fractured political system and governance, societal divisions about political goals, and democratic aspirations within an authoritarian state. This study examines the views of teachers regarding the effectiveness of Hong Kong’s current citizenship education in cultivating students’ citizenship towards the development of a democratic society. The results revealed that current citizenship education does help students foster some characteristics of good citizenship, but doubt its efficacy towards the development of democratic principles such as universal suffrage. Hong Kong is unlike many post-colonial states and Hong Kong teachers face specific challenges in terms of democratic development. While this study focuses on Hong Kong, its results are relevant to educators in other places who face similar challenges and issues under polarised and pluralised societies.

Phonology, morphology and speech processing development in Greek-speaking children

ABSTRACTΑ psycholinguistic framework for speech processing was adopted to investigate the development of phonological and morphological skills in children learning Greek. It was investigated whether morphological items pose specific challenges in terms of speech processing. Two groups of typically developing children aged 3.0–3.5 years (N = 16) and 4.6–5.0 years (N = 22), respectively, were assessed longitudinally at three assessment points 6 months apart. A range of phonologically based and morphologically based experimental speech processing tasks was administered to address the research question, along with language comprehension and production assessments to ensure that the children were developmentally typical. Stimuli of minimal phonological difference and minimal morphological difference, respectively, were used. Phonologically based experimental stimuli were used to assess performance differences across properties such as voicing, manner and place of articulation, in addition to variation in phonotactic structure. Morphologically based experimental stimuli were used to assess the impact of characteristics such as verb tense and possessive pronouns. Stimuli were incorporated into tasks of real word and nonword auditory discrimination and repetition, to assess input and output processing. Items were matched across tasks so that comparisons could be made. On most of the matched tasks, there was no significant difference in performance accuracy between morphological and phonological conditions. Moreover, a significant relationship was found between domains. It is suggested that morphological items, compared to phonological items, do not pose specific challenges in terms of speech processing. The clinical implications of these findings for assessment and intervention are discussed.

Abstract No. 572 Improving the interventional radiology lab ergonomics using a novel imaging system geometry for image-guided procedures

The interventional radiology (IR) lab work environment poses specific challenges in terms of comfort and safety for operators and patients. Table movements required for imaging and lack of system positioning flexibility are suspected to contribute to these challenges. This study evaluated the impact of a novel imaging system geometry on table movements during interventions and subsequent effects on ergonomics. 100 IR procedures were included; 50 in a traditional, widely available ceiling-mounted IR lab (A) and 50 in a lab equipped with a novel multi-axis ceiling-mounted angiography system (B) (both Philips Healthcare, Best, the Netherlands). System B was capable of 236 cm lateral x-ray detector travel in addition to traditional longitudinal travel, allowing the use of gantry- in lieu of table movements when positioning patients for imaging, as well as more flexible system positioning. After every procedure, operators evaluated patient safety, patient-/equipment positioning effort and perceived physical discomfort. Where available, system logging data from both labs were used to analyze table- and gantry movements for comparison. Median table movements per procedure were 42 and 16 (p<.001) for system A (n=36) and B (n=40) respectively. Median total table travel distance per procedure was 1998 mm for A vs. 865 mm (p=.002) for B. Operators perceived system B requiring less patient-/equipment positioning effort (p<.001). Operator discomfort during procedures was reduced for all body areas (head + neck, shoulders + upper back, arms + hands, middle + lower back and hips + legs + feet, p<.001) when comparing system A to B. Moreover system B was perceived safer for patients due to decreased risks of equipment collisions, loss of device position and pulling tubes/lines (p<.001). Novel angiography system geometry allows a reduction of the number and total travel distance of table movements, resulting in lower physical discomfort for operators. A documented significant reduction in table movements should improve patient comfort and safety and reduce patient-/equipment positioning efforts.

Cochlear Implantation in Organ Transplant Recipients

Immunosuppressed individuals who have undergone organ transplants, especially children, pose particular challenges in terms of treatment. The aim of this study was to analyze the postoperative complication rate of organ transplant recipients who have also received a cochlear implant (CI). Retrospective case series. Tertiary referral center. The case series includes 13 kidney, liver, lung, and heart transplant patients. Age at treatment ranged from 2 to 71 years, with a total of 17 CIs. Postoperative complications were classified into major and minor, early (within 3 mo postoperatively) and late (>3 mo postoperatively). The results were compared with those for 13 1:1 matched pairs obtained and from our database and a healthy patient collective from our department. The global postoperative complication rate was 29.4%. The proportion of patients suffering major complications was 17.6%, with 17.6% having minor complications. Complications that occurred early accounted for 13.3%, and late for 26.7%. No adults, and 33.0% of children, showed any complications after cochlear implantation. The global complication rate (29.4%) was significantly increased compared with the matched pairs (0%, p = 0.013) and department data (13.8%, p = 0.006; Cramers v = 0.102). This study demonstrates that organ transplant recipients, and especially children, are at increased risk of postoperative complications after cochlear implantation in comparison with healthy CI recipients.

Gap-filling a spatially explicit plant trait database: comparing imputation methods and different levels of environmental information

Abstract. The ubiquity of missing data in plant trait databases may hinder trait-based analyses of ecological patterns and processes. Spatially explicit datasets with information on intraspecific trait variability are rare but offer great promise in improving our understanding of functional biogeography. At the same time, they offer specific challenges in terms of data imputation. Here we compare statistical imputation approaches, using varying levels of environmental information, for five plant traits (leaf biomass to sapwood area ratio, leaf nitrogen content, maximum tree height, leaf mass per area and wood density) in a spatially explicit plant trait dataset of temperate and Mediterranean tree species (Ecological and Forest Inventory of Catalonia, IEFC, dataset for Catalonia, north-east Iberian Peninsula, 31 900 km2). We simulated gaps at different missingness levels (10–80 %) in a complete trait matrix, and we used overall trait means, species means, k nearest neighbours (kNN), ordinary and regression kriging, and multivariate imputation using chained equations (MICE) to impute missing trait values. We assessed these methods in terms of their accuracy and of their ability to preserve trait distributions, multi-trait correlation structure and bivariate trait relationships. The relatively good performance of mean and species mean imputations in terms of accuracy masked a poor representation of trait distributions and multivariate trait structure. Species identity improved MICE imputations for all traits, whereas forest structure and topography improved imputations for some traits. No method performed best consistently for the five studied traits, but, considering all traits and performance metrics, MICE informed by relevant ecological variables gave the best results. However, at higher missingness (&gt; 30 %), species mean imputations and regression kriging tended to outperform MICE for some traits. MICE informed by relevant ecological variables allowed us to fill the gaps in the IEFC incomplete dataset (5495 plots) and quantify imputation uncertainty. Resulting spatial patterns of the studied traits in Catalan forests were broadly similar when using species means, regression kriging or the best-performing MICE application, but some important discrepancies were observed at the local level. Our results highlight the need to assess imputation quality beyond just imputation accuracy and show that including environmental information in statistical imputation approaches yields more plausible imputations in spatially explicit plant trait datasets.

A fast 4D cone beam CT reconstruction method based on the OSC-TV algorithm.

Four-dimensional cone beam computed tomography allows for temporally resolved imaging with useful applications in radiotherapy, but raises particular challenges in terms of image quality and computation time. The purpose of this work is to develop a fast and accurate 4D algorithm by adapting a GPU-accelerated ordered subsets convex algorithm (OSC), combined with the total variation minimization regularization technique (TV). Different initialization schemes were studied to adapt the OSC-TV algorithm to 4D reconstruction: each respiratory phase was initialized either with a 3D reconstruction or a blank image. Reconstruction algorithms were tested on a dynamic numerical phantom and on a clinical dataset. 4D iterations were implemented for a cluster of 8 GPUs. All developed methods allowed for an adequate visualization of the respiratory movement and compared favorably to the McKinnon-Bates and adaptive steepest descent projection onto convex sets algorithms, while the 4D reconstructions initialized from a prior 3D reconstruction led to better overall image quality. The most suitable adaptation of OSC-TV to 4D CBCT was found to be a combination of a prior FDK reconstruction and a 4D OSC-TV reconstruction with a reconstruction time of 4.5 minutes. This relatively short reconstruction time could facilitate a clinical use.

Searching for identity and focus: towards an analytical framework for language teachers in bilingual education

ABSTRACTIn CLIL contexts, school subjects are taught in an additional language, allowing learners to acquire the target language through meaningful use. This places language teachers in an ambiguous position. What is their role in this context? On the one hand, language teachers are expected to collaborate with subject teacher colleagues; on the other hand, they teach separate language lessons. This double role provides language teachers and their educators with specific challenges in terms of identity and focus.To explore and explain the choices language teachers have, this review examines international research from the last 25 years with a primary focus on secondary schools. As recent discussions argue convincingly that research into CLIL, Content Based Instruction and immersion benefit from convergence and cross-fertilisation, we used a broad range of search terms to identify primary and secondary research.Selected articles were organised into four inquiry areas and analysed thematically: (1) language focus, (2) content focus of learning, (3) language teachers’ pedagogical practices, and (4) their collaboration with subject teachers. Based on these themes, we developed a framework for language teachers and their educators in bilingual education designed to help them explore, explain and develop their own identity and focus.

Gender related issues in thrombosis and hemostasis

ABSTRACTIntroduction: Many aspects of hemostasis, both primary and secondary, as well as fibrinolysis display sex differences. From a clinical viewpoint, certain differential phenotypic presentations clearly arise within various disorders of thrombosis and hemostasis.Areas covered: The present mini-review summarizes selected clinical entities where sex differences are reflected in both frequency and clinical presentation of hemostasis disorders. Sex differences are discussed within the settings of cardiovascular disease, including coronary artery disease and ischemic stroke, venous thromboembolism and inherited bleeding disorders. Moreover, pregnancy and labor present particular challenges in terms of increased thromboembolic and bleeding risk, and this is also summarized.Expert commentary: Available knowledge on sex differences in risk factors and clinical presentation of disorders within thrombosis and hemostasis is increasing. However, more evidence is needed to further clarify different risk factors and treatment effect in men and women, both as regards to cardiovascular disease and venous thromboembolism. This should facilitate improved gender guided risk stratification, and prevention and treatment of these diseases. Finally, risk assessment during pregnancy remains a challenge; this applies both to thromboembolic risk assessment during normal pregnancy and special care of women with inherited bleeding disorders during labor.

Clinical Evaluation of Modified Release and Immediate Release Tacrolimus Formulations.

The science of drug delivery has evolved considerably and has led to the development of multiple sustained release formulations. Each of these formulations can present particular challenges in terms of clinical evaluation and necessitate careful study to identify their optimal use in practice. Tacrolimus is an immunosuppressive agent that is widely used in organ transplant recipients. However, it is poorly soluble, has an unpredictable pharmacokinetic profile subject to important genetic polymorphisms and drug-drug interactions, and has a narrow therapeutic index. For these reasons, it represents an agent that could benefit from modified release formulations to overcome these limitations. The objective of this review is to discuss the clinical evaluation of immediate and modified release tacrolimus formulations in renal transplant recipients. Clinical trials from early development of immediate release tacrolimus to formulation-specific post-marketing trials of modified release tacrolimus formulations are reviewed with an emphasis on key elements relating to trial design end endpoint assessment. Particular elements that can be addressed with formulation alterations, such as pharmacokinetics, pharmacogenomics, and toxicity and corresponding clinical evaluations are discussed. In addition, current knowledge gaps in the clinical evaluation of immediate and modified release tacrolimus formulations are discussed to highlight potential avenues for the future development of different tacrolimus formulations with outcomes relevant to the regulators, the transplant community, and to transplant recipients. This review shows that new formulations may alter tacrolimus bioavailability, alleviate certain adverse events while potentially enhancing patient convenience.