Based on our analysis of the contributions from the connected and disconnected contraction diagrams to the pion-kaon scattering amplitude, we provide the first determination of the only free low-energy constant at , known as , in SU (4∣1) Partially-Quenched Chiral Perturbation theory using the data from the Extended Twisted Mass collaboration, . The theory uncertainties originate from the unphysical scattering length, the physical low-energy constants, the higher-order chiral corrections, the (lattice) meson masses and the pion decay constant, respectively.