Partial Small Bowel Obstruction Research Articles

Ileocecectomy is Definitive Treatment for Advanced Appendicitis

Although appendectomy is the most commonly performed emergency operation septic complications of appendectomy remain a major source of morbidity. Historically, advanced appendicitis has been treated by appendectomy with cecostomy and/or drainage tubes. Our objective was to evaluate the use of ileocecal resection for the immediate treatment of advanced appendicitis. We examined the cases of all patients undergoing ileocecal resection for appendicitis from August 1989 through April 2000. There were 92 patients (60 male and 32 female) with a median age of 34 (range 6-71). Abdominal pain was present in 98 per cent of patients with duration of 5.1+/-0.6 days. Right lower quadrant tenderness was present in 91 per cent with accompanying right lower quadrant mass in 30 per cent. Temperature on admission was 38.0+/-0.1 degrees C with a white blood cell count of 15,300+/-500. Preoperative radiological studies included abdominal X-rays (33), contrast enemas (two), CT scans (41), and abdominal ultrasound (17); these studies yielded a correct preoperative diagnosis in 89 per cent. Previous appendectomy had been performed in six patients with failed percutaneous drainage of intra-abdominal abscesses in five. There were 94 cecal resections performed in 92 patients. The extent of surgical resection varied between patients and ranged from partial cecectomy (34) to ileocecectomy (55) to ileocecectomy with diverting ileostomy (five). Intra-abdominal abscesses were present at operation in 46 cases (50%), and drains were placed in 38 (41%). Skin incisions were packed open in most cases (65); there was skin closure in 27. There was no mortality encountered in this period. There were 25 complications in 23 patients (25%). Complications included postoperative abscess (10; 11%), wound infection (10; 11%), partial small bowel obstruction (two) and pulmonary embolus (one). Reoperation was required in seven patients and CT-guided percutaneous drainage in five patients. Anastomic leaks occurred in two cases of partial cecectomy and required conversion to ileocecectomy. Mean hospital stay was 10.5+/-1.0 days with adjusted hospital costs of $31,689+/-3018. We conclude that definitive treatment of advanced appendicitis can be performed by resection of the involved areas of the ileocecum. This can be accomplished with a primary anastomosis obviating the need for ileostomy and secondary operation. This aggressive surgical approach may reduce infectious complications and reduce hospital costs.

Fruit pit obstruction leading to the diagnosis of Crohn’s disease

A 62-year-old man with a medical history of degenerative joint disease was admitted for evaluation of progressive cramping, right lower quadrant abdominal pain associated with low grade fever, anorexia, emesis, distention, and diminished passage of flatus and feces. His surgical history was significant for a left inguinal hernia repair. On physical examination, the abdomen was soft but distended, with right lower quadrant tenderness. Bowel sounds were present. No rebound tenderness or involuntary guarding was elicited on palpation. Laboratory data were unremarkable. Abdominal radiographs revealed a dilated small bowel with multiple air fluid levels. The patient was admitted with the presumptive diagnosis of partial small bowel obstruction. He underwent abdominal computed tomography (CT) scan Fig. 1, which revealed a well-delineated, ring-like foreign body with surrounding mucosal thickening in the terminal ileum (arrow). Over the next 2 days, the patient’s abdomen remained distended and remarkably tender to palpation. A repeat abdominal CT, performed to determine further progression of this density, was without change. Exploratory laparotomy revealed inflammation and obstruction of the terminal ileum. The resected segment of terminal ileum demonstrated histologic changes consistent with Crohn’s disease and also revealed a 3.4 2.2 1.5 cm plum pit impacted in a highly strictured distal portion of terminal ileum near the ileocecal valve (Fig. 2). During the postoperative period, the patient recalled inadvertently swallowing a plum pit 2 days before admission. He had an uneventful postoperative course and was discharged in stable condition. Fruit pit ingestion is an unusual cause of intestinal obstruction—and even more so in our patient as it led to the discovery of Crohn’s disease. Management of foreign body ingestion has long been conservative, entailing close observation, as most objects pass through the gastrointestinal tract without incident. Intestinal obstruction and perforation are rare but potential complications; however, the patient with intrinsic bowel disease is potentially at a greater risk of

Chronic Intermittent Intestinal Obstruction From a Seat Belt Injury

Most patients with intestinal obstruction have had previous surgery. Rarely, the development of adhesions and resulting small bowel obstruction is attributed to previous intra-abdominal trauma. We present the case of a young man, without a history of surgery, who had been a restrained driver in a motor vehicle crash. Seven years later, the patient had an intermittent partial small bowel obstruction that recurred over the next 5 years. We review the pathophysiology and epidemiology of similar occurrences, as well as diagnostic options.

Mechanical Partial Small Bowel Obstruction in a Patient with Fitz-Hugh-Curtis Syndrome

Perihepatitis or Fitz-Hugh-Curtis syndrome is a complication of pelvic inflammatory disease that usually leaves characteristic violin string adhesions on the anterior liver surface. These adhesions are common incidental findings on subsequent laparoscopy or laparotomy and are considered benign. We present a case of partial mechanical small bowel obstruction as a sequel of this syndrome that was diagnosed and treated laparoscopically.

Utility of computed tomographic enteroclysis for the general surgeon

PurposeEnteroclysis uses contrast fluid distention of the small bowel through a jejunal catheter with flouroscopic imaging to identify abnormalities. Computed tomograpic enteroclysis (CT-E) adds cross-sectional imaging to identify small bowel pathology to include masses, gastrointestinal bleeding of unknown origin, and partial obstruction. Computed tomography-enteroclysis is being used more frequently in the assessment of patients with possible small bowel pathology. This study examines the applicability of CT-E and its superiority over conventional enteroclysis. MethodsA retrospective chart review was used to examine all CT-E and enteroclysis studies performed at our institution during a 24-month period (August 1997 to August 1999). All patients that had received CT-E or enteroclysis were divided into 3 categories; group I: small bowel mass, group II: gastrointestinal bleeding, and group III: partial small bowel obstruction (pSBO). All patients included had received other radiological procedures based on the indication for examination to include esophagogastroduodenoscopy, colonoscopy, CT, abdominal x-rays, barium enema, and upper gastrointestinal with small bowel follow-through. ResultsForty-nine studies were performed, with enteroclysis or CT-E, used in 46 patients. Median age was 62 years (M:F, 1:1). In group 1 (n = 10), no masses were noted, but all patients identified as having a mass on previous studies (n = 6) were determined not to have a mass by CT-E (n = 1) and enteroclysis (n = 5). In group II (n = 19), 1 small bowel source (jejujunal arteriovenous malformation) was identified through CT-E, and all other studies in both categories were negative/normal. In group III (n = 20), 5 pSBO were identified through CT-E that had not been previously described. ConclusionsEnteroclysis and CT-E are both effective at disproving the presence of small bowel masses discovered through less-specific radiological methods. In terms of gastrointestinal bleeding, CT-E is as effective as enteroclysis at identifying source of bleeding and may have an added role through its ability to better identify anatomic relationships. Computed tomography-enteroclysis was able to determine the presence of pSBO in 5 patients that previously had been undiagnosed. In conclusion, enteroclysis remains an effective radiological study for examination of the small bowel. Computed tomography-enteroclysis matches that effectiveness with the added benefit on high-resolution anatomic images that serve it well as an additional diagnostic tool for the General Surgeon in patients with difficult to diagnose small bowel pathology.

Postlaparoscopic Small Bowel Obstruction Secondary to Unrecognized Nodular Endometriosis of the Terminal Ileum

Small bowel involvement by endometriosis occurs in about 0.5% of patients, but nodular endometriosis involving the entire wall of the terminal ileum is extremely rare. Endometriotic nodules protruding into the intestinal lumen may lead to chronic, partial, or acute complete small bowel obstruction and associated clinical changes. If obstruction is partial, preoperative diagnosis is difficult and seldom suspected, and no reliable diagnostic tests are available. At laparoscopic surgery, performed typically for associated pelvic endometriosis, bowel lesions may easily be overlooked, especially in women with abdominal adhesions from earlier surgery. Surgical injury, tension tears, or postoperative edema may contribute in such cases to the development of acute, complete small bowel obstruction, which may be difficult to differentiate from postoperative ileus. The patient may deteriorate rapidly and develop abdominal sepsis and multiple organ failure with high risk of mortality. Because of increased production of tumor necrosis factor-α by autologous monocytes, endometriosis may predispose to development of severe sepsis and septic shock.

Abdominal radiography findings in small-bowel obstruction: relevance to triage for additional diagnostic imaging.

Our aim was to determine which findings on abdominal radiography are relevant for distinguishing complete or high-grade partial small-bowel obstruction from low-grade partial or no small-bowel obstruction. Admitting abdominal radiographs with the patients in the supine and upright positions were scored for 25 different findings in 81 patients with clinically suspected small-bowel obstruction. Forty-one patients had complete or high-grade partial small-bowel obstruction, and 40 had low-grade partial small-bowel obstruction or no obstruction as determined by enteroclysis examination. Abdominal radiography findings were subjected to statistical analysis for correlation with degree of obstruction. Of 12 radiographic findings strongly associated (p < 0.05) with the severity of obstruction, two findings were found to be the most significant (p < or = 0.0003) and predictive of a higher grade small-bowel obstruction: the presence of air-fluid levels of differential height in the same small-bowel loop and the presence of a mean air-fluid level width greater than or equal to 25 mm on upright abdominal radiographs. When both critical findings are present, the degree of small-bowel obstruction is likely high-grade or complete. When both signs are absent, small-bowel obstruction is likely low-grade or nonexistent. Upright abdominal radiographs are important in the examination of patients with suspected small-bowel obstruction and may contribute to the imaging triage of these patients.

Small volume hyperosmolar abdominal CT in acute small bowel obstruction

Purpose: Identification of the degree of small bowel obstruction (SBO) is helpful in patient management decisions since the treatment of partial SBO is nonoperative, whereas the treatment of complete SBO requires surgical intervention. We describe a technique providing the benefits of CT and enteroclysis together, which allows the radiologist to determine the degree of the SBO and thereby to distinguish partial from complete SBO. Methods and materials: Abdominal CT scans were performed on 21 patients. Patients were given 200 ml concentrated oral contrast medium. Serial radiographs followed the progression of contrast at 1, 3, and 5 h in order to optimize the timing of the abdominal CT. A partial SBO was diagnosed if the oral contrast reached the colon at or before the 5-h film, and a complete SBO if the oral contrast did not reach the colon by the 5-h abdominal radiograph. The CT was performed when the contrast reached the colon or after the 5-h film. Results: CT findings demonstrated complete obstruction in eight patients, all of whom required surgical treatment. Partial SBO was demonstrated in 13 patients. Ten of the 13 patients with partial SBO had an uncomplicated transition zone, probably due to adhesions, and were treated medically. Nine of these patients were managed with nasogastric tube decompression and were discharged without surgical intervention. One patient failed to respond to a 12-h course of nasogastric tube decompression and underwent lysis of adhesions. Three of the 13 patients had a complicated transition zone, due to an intussusception and two hernias, which were responsible for the SBO. Two were treated surgically and one medically. Conclusion: The use of small-volume hyperosmolar abdominal CT allows the radiologist to determine the degree of the SBO. This additional information is very useful in patient management because uncomplicated partial SBO is often treated successfully via tube decompression, whereas complete SBO requires surgical intervention.

EARLY NASOGASTRIC TUBE REMOVAL COMBINED WITH METOCLOPRAMIDE AFTER RADICAL CYSTECTOMY AND URINARY DIVERSION

Prolonged nasogastric decompression increases pulmonary complications by inhibiting clearance of respiratory secretions. The literature supports early nasogastric tube removal following bowel resection. Metoclopramide stimulates bowel activity, promoting return of function. We examined combining early nasogastric tube removal with metoclopramide after radical cystectomy. From 1994 to 1996, 27 prospective cystectomy patients received intravenous metoclopramide (metoclopramide group) combined with early nasogastric tube removal (less than 24 hours). A total of 54 concurrent cystectomy controls received no metoclopramide and nasogastric tubes remained until return of normal bowel function. Preoperative and perioperative factors were comparable between the 2 groups. Nasogastric tubes were removed from 78% of the metoclopramide group in less than 24 hours, 11% on day 2 and 11% on day 3 compared to none on day 1, 50% on day 2 and 50% on day 3 or greater in controls. The metoclopramide group had a more rapid return of normal bowel sounds (2.9 versus 4.0 days, p = 0.0002) and earlier tolerance of solid food (6.7 versus 7.9 days, p = 0.04). Nasogastric tube replacement was required in 3 of 27 metoclopramide cases versus 5 of 54 controls. Atelectasis occurred more often in the control group (33 versus 15%). There were no bowel related complications in the metoclopramide group but partial small bowel obstruction in 2 controls was treated conservatively. This preliminary study suggests that combining intravenous metoclopramide with early nasogastric tube removal after cystectomy and urinary diversion may reduce postoperative atelectasis and speed return of bowel function while posing no danger to the small bowel anastomosis. This regimen may result in fewer complications and shorter hospitalizations, translating into lower costs without compromising quality of care.

The Utility and Reliability of Computed Tomography Scan in the Diagnosis of Small Bowel Obstruction

Accurate diagnosis and treatment of small bowel obstruction (SBO) is critical to prevent complications and reduce costs. The purpose of the current study was to evaluate the evolving role of CT scan for patients with suspected SBO and compare its sensitivity and specificity with plain abdominal films. We identified 108 patients over a 1-year period with an admission or discharge diagnosis of SBO. Five patients treated on a clinical basis without radiographic imaging and those with indeterminate films were excluded from analysis. CT and radiograph reports were compared with operative findings or clinical course in 103 patients. By the clinical course, 66 of the patients had a partial or complete SBO. Plain film radiography correctly established the diagnosis of SBO in 50 of 66 patients (sensitivity, 75%). Nine of 17 plain films were true negatives (specificity, 53%). CT was able to correctly identify partial or complete SBO in 35 of 38 patients (sensitivity, 92%) and correctly identified the lack of obstruction in 8 of 13 patients (specificity, 71%). These data document that plain films are a less sensitive and less specific method of diagnosing SBO and confirm that the use of CT scan is a valuable modality. CT scan should be considered for use as the primary test for patients with suspected SBO.

Comparison of computed tomography-enteroclysis and traditional computed tomography in the setting of suspected partial small bowel obstruction

Traditional computed tomography (CT) is sometimes limited in its ability to diagnose partial small bowel obstruction (SBO), especially if low grade. Standard enteroclysis is sensitive in diagnosing partial SBO; however, extraluminal abnormalities are not well visualized. CT-enteroclysis (CT-E) offers both crosssectional imaging and a contrast volume challenge. CT-E is compared to traditional abdominal/pelvic CT to identify any group(s) of patients who might benefit from having CT-E as the front-line examination.

Complications of absorbable pelvic mesh slings following surgery for rectal carcinoma.

To evaluate the intraoperative, postoperative, and long-term complications of an absorbable pelvic mesh sling after surgery for rectal carcinoma. A retrospective review of medical records from April 8, 1991, through April 8, 1996. Twenty patients with a mean age of 57 (range, 37-79) years underwent pelvic mesh sling placement. The tumor stages were as follows: Stage I, 5; Stage II, 2; Stage III, 11; and Stage IV, 1. A recurrent perianal basal cell carcinoma was not included in the staging group. Surgery consisted of 18 abdominoperineal resections, 1 total proctocolectomy, and one Hartmann's procedure. Mean follow-up was 18 (range, 2-49) months. There were no intraoperative complications related to mesh placement. Twenty-nine complications occurred in 14 patients during the immediate postoperative period. Five were possibly mesh-related and included a pelvic abscess, perineal seroma, toxic perineal wound, pulmonary embolus, and lower extremity deep venous thrombosis, respectively. A mild postoperative ileus developed in 17 patients (85 percent), and a diet was initiated at a mean of seven (range, 4-24) days. Fourteen patients received postoperative radiotherapy with a mean dose of 5,339 (range, 2,500-7,020) cGy delivered in 180-cGy fractions. There were 14 immediate complications caused by radiotherapy in 11 patients, but only two patients required delays in treatment. Two patients had diarrhea alone, six developed perineal dermatitis alone, and three patients had both diarrhea and perineal dermatitis. All patients with diarrhea had received chemoradiation. One patient developed a partial small-bowel obstruction following radiation. Absorbable pelvic mesh sling placement can be performed with minimum morbidity and is recommended following surgery for rectal cancer when radiation is anticipated as part of multimodality therapy.

THE HAUTMANN NEOBLADDER WITH A CHIMNEY: A VERSATILE MODIFICATION

We describe a modification to the popular Hautmann ileal neobladder comprised of a chimney for the ureterointestinal anastomosis in order to enhance its flexibility, reduce its pitfalls and hence make more patients candidates for this type of diversion. The Hautmann ileal neobladder is prepared in the standard fashion except that an additional 5 to 10 cm. (or more if needed in the case of a short ureter) of small bowel are selected to be added for either a left or right "chimney" (depending on which side the ureter may be shorter or if there is a solitary kidney). The V segment of the W which will be anastomosed to the urethra is made longer than the contralateral V segment. A neobladder neck is created by sewing together the cut edges of a 5 cm. lip in the lowermost W configuration of the neobladder, allowing an end-to-end urethrointestinal anastomosis. Between March and October 1996, 3 patients have undergone this procedure at the University of Virginia. Two had right chimneys and 1 had a left chimney. Followup is short, but there have been no complications except for a transient postoperative partial small bowel obstruction in 1 patient. Two patients have no urinary incontinence, the third has only occasional nocturnal incontinence. This modification of the Hautmann ileal neobladder provides greater versatility for short ureters, minimizes tension from the mesentery on the urethrointestinal anastomosis, simplifies the ureterointestinal anastomosis and provides easy postoperative access for ureterointestinal anastomosis revision or resection in case of recurrent disease.

Gastrointestinal myoelectric activity in a child with gastroschisis and ileal atresia

Gastroschisis is frequently associated with intestinal atresia and alterations in gastrointestinal function. The authors studied gastric and small bowel myoelectric activity in a child who had a complex course and prolonged inability to tolerate oral intake after staged repair of gastroschisis and an associated ileal atresia. The child remained unable to tolerate oral intake after repair of the atresia and was reexplored 3 months later to rule out a partial small bowel obstruction, with simultaneous placement of serosal electrodes on the stomach and proximal small bowel. Persistent gastric dysrhythmias were observed postoperatively, and the child was unable to tolerate gastrostomy tube feedings. Abnormalities were also seen in small bowel motility, including retrograde propagation of activity fronts of the migrating myoelectric complex. However, the intestine converted to a fed myoelectric pattern with tube feedings, and the child was subsequently able to tolerate feedings via a tube placed directly into the small bowel. The authors conclude that myoelectric recordings via implanted electrodes are safe and feasible in children, and may give information regarding underlying motility alterations. The ultimate clinical role of myoelectric recordings in treating children with suspected motility disorders will require further study.

Diagnosis and management of small intestinal diseases

Topics related to the diagnosis of small intestinal diseases that are covered in this review include a potential new serum marker for intestinal infarction; an improved diagnostic test for Whipple's disease; diagnostic enteroscopy; the use of marker studies to help diagnose and localize the site of partial small bowel obstruction; and the use of a color card to help localize the source of rectal bleeding. Treatment topics include the use of urokinase for acute superior mesenteric vein or portal vein thrombosis; the use of nasogastric versus long intestinal drainage tubes for acute adhesive small bowel obstruction; guidelines for the use of octreotide to treat secretory diarrhea; and the use of patient-controlled analgesia pumps after uncomplicated colonic surgery and postoperative ileus.

Value of radiopaque markers in identifying partial small bowel obstruction

Confirming partial small bowel obstruction is often a diagnostic challenge. In this case report, 4-mm solid radiopaque markers were used in 4 patients to show partial small bowel obstruction. Results of enteroclysis were normal in 2 of the 4 patients, and the markers were used to challenge suspected partial obstruction. The markers coalesced in the region of the partial obstruction, which was confirmed at surgery. Enteroclysis is the examination of choice in the diagnosis of partial small bowel obstruction. However, examinations with false- negative results can occur, particularly with adhesive and/or intermittent obstructions. The use of radiopaque markers in these cases proved an effective and useful method of establishing the diagnosis of partial small bowel obstruction, particularly in the 2 cases in which enteroclysis results were normal. Prospective studies are needed to establish the feasibility of this novel technique. (Gastroenterology 1996 Jun;110(6):1958-63)

Computed tomographic diagnosis of partial small bowel obstruction secondary to anterior peritoneal adhesions: relevance to laparoscopic cholecystectomy

A case is reported of partial small bowel obstruction secondary to anterior peritoneal adhesions which resulted in inadvertent trocar perforation of the small bowel at laparoscopic cholecystectomy. Careful assessment of computed tomographic examinations performed for acute abdominal complaints should include diagnosis of lower grades of small bowel obstruction from peritoneal adhesive disease. Laparoscopic surgeons should be apprised of peritoneal adhesions of bowel at usual sites of needle or trocar puncture.

Computed Tomographic Enteroclysis

Computed tomography (CT) is limited in the assessment of partial small bowel obstruction (SBO). Enteroclysis is preferred but gives little direct information about the bowel wall, mesentery, or remote findings. Preliminary results of a combined CT enteroclysis (CT-E) methodology are reported. Forty-eight patients with suspected partial SBO underwent a water soluble contrast enteroclysis followed immediately by CT. Pump rates at fluoroscopy and CT were 75 to 100 cc/min unless a high-grade obstruction was encountered at fluoroscopy. Shrake's criteria for complete, high-grade or low-grade partial SBO were used. The calculated dose per patient was 27 rad for CT-E as opposed to 32 rad with traditional enteroclysis. Site specific sensitivity and specificity for low-grade partial SBO, were 82.1% and 87.5%. One death was encountered in a patient with diffuse abdominal metastatic disease and complete obstruction. This was caused by vomiting and aspiration secondary to tube placement alone, CT-enteroclysis having been aborted. Computed tomographic enteroclysis is a diagnostic option for evaluation of low-grade partial SBOs. Pitfalls with this technique are encountered in decompressed torsions and hernias.

Flare-up of endometriosis induced by gonadotropin-releasing hormone agonist leading to bowel obstruction

To report a case of intestinal obstruction that developed shortly after preoperative administration of a GnRH analogue (GnRH-a) that caused flare-up and rapid progression of enteric endometriosis. Case report. University tertiary reproductive endocrinology practice. A 34-year-old nulligravid female with progressive severe symptomatic endometriosis. Planned preoperative administration of GnRH-a for 3 months followed by extirpative surgery and hormone replacement therapy. Instead, total abdominal hysterectomy, bilateral salpingoophorectomy, resection of the obstructed ileocecal junction, and side-to-side ileo-ascending enterocolostomy was performed. Preoperative GnRH-a administered in the midfollicular phase resulted in flare-up of preexisting ileocecal endometriosis that rapidly progressed, resulting in partial small bowel obstruction. Gonadotropin-releasing hormone agonist should be used with caution when there is known or suspected enteric endometriosis. Consideration should be given to blocking the agonistic effect of GnRH-a in this setting by the prior or concomitant use of progestins or danazol.

Phase I feasibility and pharmacologic study of weekly intraperitoneal paclitaxel: a Gynecologic Oncology Group pilot Study.

This study was designed to define the maximum-tolerated dose (MTD) and pharmacology of paclitaxel administered by the intraperitoneal (IP) route on a weekly schedule. Thirty-three patients with residual ovarian cancer following standard chemotherapy were entered onto this phase I trial. Patients were treated weekly with IP paclitaxel administered in 2 L of normal saline following premedication. Patients with nonassessable disease received 16 weekly courses. The initial dose level was 20 mg/m2/wk. There was no intrapatient dose escalation. Multiple grade 2 toxicities were observed at the 75-mg/m2/wk dose level. These toxicities included abdominal pain, nausea, vomiting, leukopenia, and fatigue. One episode of grade 4 vomiting thought to be secondary to a transient partial small-bowel obstruction occurred at this dose level. At dose levels > or = 60 to 65 mg/m2, pharmacology studies documented the persistence of significant IP paclitaxel levels 1 week after drug administration, suggesting very slow peritoneal clearance and continuous exposure of the peritoneal cavity to active concentrations of paclitaxel. Low plasma paclitaxel concentrations were detected in the majority of patients treated at dose levels > or = 55 mg/m2. Paclitaxel can be delivered by the IP route on a weekly schedule with both an acceptable toxicity profile and a major pharmacokinetic advantage for cavity exposure. The recommended dose and schedule for phase II study of IP paclitaxel is 60 to 65 mg/m2 weekly.