Partial Retrieval Research Articles

Metacognitive processes accompanying the first stages of autobiographical retrieval in the self-memory system

ABSTRACT According to Conway’s view, Autobiographical memory (AM) construction is accompanied by control processes. These processes range from filtering out relevant memories according to the current context, to generating or elaborating appropriate retrieval cues. These processes can be conceptualised as metacognition, the ability to control and monitor cognitive processes. Experimentally, little has been carried out to support the idea that metacognition is involved in AM. To assess this, we designed a task, the Feeling of Retrieval. Participants had to predict whether cue words would facilitate AM access (i.e., fluent access cues) or not (i.e., limited access cues) in a limited time (either 1 (Exp. 2) or 2 (Exp. 1) s). Later, they retrieved memories in response to both types of cues. Results show that cues judged as fluent access led to better AM generation, as illustrated by AM retrieval latency and a subjective measure of the ease with which the AMs were retrieved. These rapid predictions may rely on epistemic feelings and / or other mnemonic cues such as a partial retrieval of information. This metacognitive access to the earliest stages of AM retrieval illustrates the ability to monitor AM processes as proposed by Conway (2005).

Geometric Feature-Based Partial Retrieval of On-Machine Measurement Models

Geometric Feature-Based Partial Retrieval of On-Machine Measurement Models

Subjective Experience of Word Production Difficulties in Aphasia: a Metaphor Analysis of Autobiographical Accounts

ABSTRACT Background and aims The subjective experience of neurological symptoms provides useful information for assessment, intervention and care. However, research in the subjective experience of aphasia is limited. Word production difficulties are universal to aphasia, and interdisciplinary research has produced sophisticated models of the multiple stages and processes involved. Critically, this word-production research does not incorporate the subjective experience of symptoms. We carried out a metaphor-led discourse analysis on autobiographical accounts written by people with aphasia, to determine whether subjective descriptions of word finding difficulties are consistent with the stages and processes of psycholinguistic models. Method Metaphor-led discourse analysis was used to identify, code and interpret metaphorical expressions describing word production difficulties in 12 English-language autobiographical accounts written by people with aphasia. These expressions were then analysed to determine the systematic metaphors (i.e., the related concepts which are used consistently to describe a particular topic). Two distinct types of systematic metaphor emerged in the analysis: conventional systematic metaphors frequently recurring throughout all or most of the accounts; novel systematic metaphors used in one or two extended passages in an overlapping subset of the accounts. Results and discussion 4020 metaphorical expressions described word production, predominantly using conventional metaphors about communication and cognition. The conventional metaphor WORD-PRODUCTION AS MOVING OBJECTS OUT OF A CONTAINER was the most prevalent, with elaborations and variations allowing mapping of different symptoms. Other conventional metaphors included: WORD PRODUCTION AS A JOURNEY/HUNTING/HERDING THROUGH A LANDSCAPE, allowing description of effortful or partial retrieval, neuroplastic recovery, and internal strategies; APHASIA AS BODILY IMPAIRMENT, which described various symptoms in terms of different body parts, including self-monitoring difficulties; and APHASIA AS FRAGMENTATION AND PERSONIFICATION OF SELF and SELF AS MACHINE/COMPUTER to describe a disrupted sense of agency and attention. Novel systematic metaphors were used to describe certain symptoms: APHASIA AS SILENCE and APHASIA AS SPIRITUAL EXPERIENCE were used to describe a lack of ‘inner speech’, and APHASIA AS A DISMEMBERED TREE to describe problems making semantic associations. Conclusions and implications This research demonstrates the many consistencies of subjective descriptions of word production difficulties in aphasia with theoretical models, but also shows that some subjectively salient symptoms, in particular attentional and self-monitoring difficulties, and a lack of inner speech, are not captured by all theoretical models. Careful attention to the way that people with aphasia describe their symptoms can provide a valuable source of information to be integrated with objective measures.

How Can We Predict Disease Severity in Viral Infections?

How Can We Predict Disease Severity in Viral Infections?

Effect of Direct Acting Antivirals (DAAs) on Myeloid-Derived Suppressor Cells Population in Egyptian Chronic Hepatitis C Virus Patients: A Potential Immunomodulatory Role of DAAs.

Chronic hepatitis C is a major health concern with high morbidity and mortality rates. The introduction of direct acting antivirals (DAAs) as a first-line treatment for hepatitis C virus (HCV) has significantly enhanced HCV eradication. However, DAA therapy is facing rising concerns regarding long-term safety, viral resistance, and reinfection. HCV is associated with different immune alteration mechanisms that can evade immunity and establish persistent infection. One of these suggested mechanisms is the accumulation of myeloid-derived suppressor cells (MDSCs), which is known to accumulate in chronic inflammatory conditions. Moreover, the role of DAA in restoring immunity after successful viral eradication is still unclear and needs further investigations. Thus, we aimed to investigate the role of MDSCs in chronic HCV Egyptian patients and its response to DAA in treated compared with untreated patients. Fifty untreated chronic hepatitis C (CHC) patients, 50 DAA-treated CHC patients, and 30 healthy individuals were recruited. We used flow cytometer analysis to measure MDSCs frequency and enzyme-linked immunosorbent assay analysis to evaluate the serum level of interferon (IFN)-γ. We found a significant elevation in MDSC% among the untreated group (34.5 ± 12.4%) compared with the DAA-treated group (18.3 ± 6.7%), while the control group had a mean of (3.8 ± 1.6%). IFN-γ concentration was higher in treated patients compared with untreated. We also found a significant negative correlation (rs -0.662) (p < 0.001) between MDSC% and IFN-γ concentration among treated HCV patients. Our results revealed important evidence of MDSCs accumulation in CHC patients and partial retrieval of the immune system regulatory function after DAA therapy.

Random access codes via quantum contextual redundancy

We propose a protocol to encode classical bits in the measurement statistics of many-body Pauli observables, leveraging quantum correlations for a random access code. Measurement contexts built with these observables yield outcomes with intrinsic redundancy, something we exploit by encoding the data into a set of convenient context eigenstates. This allows to randomly access the encoded data with few resources. The eigenstates used are highly entangled and can be generated by a discretely-parametrized quantum circuit of low depth. Applications of this protocol include algorithms requiring large-data storage with only partial retrieval, as is the case of decision trees. Using n-qubit states, this Quantum Random Access Code has greater success probability than its classical counterpart for n&amp;#x2265;14 and than previous Quantum Random Access Codes for n&amp;#x2265;16. Furthermore, for n&amp;#x2265;18, it can be amplified into a nearly-lossless compression protocol with success probability 0.999 and compression ratio O(n2/2n). The data it can store is equal to Google-Drive server capacity for n=44, and to a brute-force solution for chess (what to do on any board configuration) for n=100.

Comparison of mechanical thrombectomy techniques in an in vitro stroke model: How to obtain a first pass recanalization?

BackgroundSince mechanical thrombectomy (MT) has proven to be effective in the treatment of acute ischemic stroke (AIS), significant research has been dedicated to establishing procedural techniques offering best rate of first pass effect (FPE). In this study, we compared the efficacy of different techniques in vitro to achieve the first pass recanalisation (FPR). MethodsIn vitro MT procedures were performed using a realistic silicone model of the human cerebral vasculature. The MT with stent retriever (SR) were performed with manual co-aspiration through the respective access catheter and intermediate catheter (IC), with Solumbra or partial retrieval techniques into the IC. Two SRs (Solitaire and EmboTrap) were selected to retrieve both red blood cells (RBC) rich and fibrin-rich clots. FPR rates were recorded for each case. ResultsOverall, 144 MT were performed. FPR rates using the partial retrieval and Solumbra technique were of 100% and 87%, respectively (p = 0.01). The rate of FPR was of 92% using the balloon-guide catheter (BGC) compared to 64% with the guide catheter (GC) (p = 0.0001). With an IC, no differences were found between using a BGC or a GC (87.9% vs 89,6%, p = 0.75). No significant difference was observed between the Embotrap and the Solitaire device for the rate of FPR (82% and 74%, respectively; p = 0.23). ConclusionsIn this study, FPR rates were higher with the use of an IC associated with the partial retrieval technique, regardless the guide catheter, the SR, or the clot composition. The less effective technique was the association of GC and SR, without an IC.

Characteristics of Tip of the Tongue Phenomenon on the Task of Naming Celebrities in Healthy Elderly Adults

Objectives: In general, the incidence of Tip of the tongue (TOT) phenomenon increases with age, but studies on the difference in the incidence of TOT phenomenon according to the age of healthy elderly adults are limited. The purpose of this study was to investigate the incidence and resolution rate of the TOT, and to find out the change in performance according to the syllabic clues.Methods: Ninety-six healthy elderly people whose age range was between 65 and 84 years old participated in the study. Participants were divided into three groups: 55-64 years old, 65-74 years old, and 75-84 years old age range groups. The TOT task used 30 questions about celebrity naming organized by period and category.Results: First, there was a significant difference of the TOT rate by age group, and as the age increased, the TOT rate due to partial retrieval failure and total retrieval failure increased. Second, the rate of TOT response type that explained the celebrity’s occupation was the highest in all groups. Third, there were significant differences between groups in both the voluntary TOT resolution rate and the TOT resolution rate after providing the syllabic clue. The recovery rate after the syllabic clues decreased with increasing age.Conclusion: This study observed the difference in characteristics of TOT phenomenon in elderly adults according to age group and the importance of phonological clues in TOT phenomenon resolution.

Degree of learning and linear forgetting.

The aim of this study was to assess whether the degree of learning influences the observation of memory retention and forgetting that follows a linear pattern. According to our retention accuracy from fragmented traces (RAFT) model, one factor that should increase the likelihood of this is when there is greater learning of the material. Higher levels of learning can increase the number of trace components, making it more likely that reconstruction or partial retrieval can lead to an accurate response on a memory test. Here, we report three new experiments, as well as re-analyses of existing data from the literature, to show that increasing the level of learning in some ways can lead to increases in the likelihood of observing linear forgetting. For Experiment 1, people learned materials to different levels. This learning involved cued recall testing during memorisation. Linear forgetting was observed with increased learning. For Experiment 2, learning did not involve cued recall testing. Linear forgetting was not observed. Although our aim was not to test theories of retrieval practice, for Experiment 3, we showed that when people engage in this process, the pattern of retention and forgetting becomes more linear. Overall, these data are consistent with the RAFT theory and support mechanisms that it suggests can lead to the observation of linear forgetting.

Magisterial authority and competing theories of natural law in Calvin'sInstitutes

AbstractIn this paper, I argue that John Calvin's problematic grant of magisterial authority to enforce proper religious worship contradicts much of his own political theology and in fact depends upon an ambiguity in his natural law theory. I demonstrate this ambiguity by examining the differing claims in theInstitutesregarding which of the tables of the Decalogue are accessible through natural law reasoning. I also consider the significance of this ambiguity for Calvin's political theology. I then suggest a partial retrieval of Calvin's political theology which is both more compelling to many contemporary Christians and in a better alignment with much of Calvin's own political theory.

Multifeatured Image Retrieval Techniques Based on Partial Differential Equations for Online Shopping

In today’s rapid development of network and multimedia technology, the booming of electronic commerce, users in the network shopping species of images and other multimedia information showing geometric growth, in the face of this situation, how to find the images they need in the vast amount of online shopping images has become an urgent problem to solve. This paper is based on the partial differential equation to do the following research: Based on the partial differential equation is a kind of equation that simulates the human visual perception system to analyze images; based on the summary of the advantages and disadvantages of multifeature image retrieval technology, we propose a multifeature image retrieval technology method based on the partial differential equation to alleviate the indexing imbalance caused by the mismatch of multifeature image retrieval technology distribution. To improve the search speed of the data-dependent locally sensitive hashing algorithm, we propose a query pruning algorithm compatible with the proposed partial differential equation-based multifeature image retrieval technology method, which greatly improves the retrieval speed while ensuring the retrieval accuracy; to implement the data-dependent partial differential equation algorithm, we need to distribute the data set among different operation nodes, and to better achieve better parallelization of operations, we need to measure the similarity between categories, and we achieve the problem of distributing data among various categories in each operation node by introducing a clustering method with constraints. The purpose of this article for image recognition is for better shopping platforms for merchants. This algorithm has trained multiple samples and has data support. The experimental results show that our proposed data set allocation method shows significant advantages over the data set allocation method that does not consider category correlation. However, the image features used in image retrieval systems are often hundreds or even thousands of dimensions, and these features are not only high in dimensionality but also huge in number, which makes image retrieval systems encounter an inevitable problem—“dimensionality disaster.” To overcome this problem, scholars have proposed a series of approximate nearest neighbor methods, but multifeature image retrieval techniques based on partial differential equations are more widely used in people’s daily life.

Partial 3D object retrieval using local binary QUICCI descriptors and dissimilarity tree indexing

A complete pipeline is presented for accurate and efficient partial 3D object retrieval based on Quick Intersection Count Change Image (QUICCI) binary local descriptors and a novel indexing tree. It is shown how a modification to the QUICCI query descriptor makes it ideal for partial retrieval. An indexing structure called Dissimilarity Tree is proposed which can significantly accelerate searching the large space of local descriptors; this is applicable to QUICCI and other binary descriptors. The index exploits the distribution of bits within descriptors for efficient retrieval. The retrieval pipeline is tested on the artificial part of SHREC’16 dataset with near-ideal retrieval results.

Retrieval of Cloud Liquid Water Using Microwave Signals from LEO Satellites: A Feasibility Study through Simulations

A novel approach, using low Earth orbit (LEO) satellite microwave communication links for cloud liquid water measurements, is proposed in this paper. The feasibility of this approach is studied through simulations of the retrieval system including a LEO satellite communicating with a group of ground receivers equipped with signal-to-noise ratio (SNR) estimators, a synthetic cloud attenuation field and a tomographic retrieval algorithm. Rectangular and Gaussian basis functions are considered to define the targeted field. Simulation results suggest that the proposed least-squares based retrieval algorithm produces satisfactory outcomes for both types of basis functions. The root-mean-square error of the retrieved field is around 0.2 dB/km, with the range of the reference field as 0 to 2.35 dB/km. It is also confirmed that the partial retrieval of the cloud field is achievable when a limited number of receivers with restricted locations are available. The retrieval outcomes exhibit properties of high resolution and low error, indicating that the proposed approach has great potential for cloud observations.

Deterministic generation and partial retrieval of a spin-wave excitation in an atomic ensemble.

In this paper, we report a generation of a spin-wave excitation (SWE) with a near-unity (0.996±0.003) probability in a given time (~730 μ s). Such deterministic generation relies on a feedback scheme with a millisecond quantum memory. The millisecond memory is achieved by maximizing the wavelength of the spin wave and storing the SWE as the magnetic-field-insensitive transition. We then demonstrate partial retrievals of the spin wave by applying a first read pulse whose area is smaller than the value of π. The remained SWE is fully retrieved by a second pulse. Anti-correlation function between the detections in the first and second readouts has been measured, which shows that the partial-retrieval operation on the SWE is in the quantum regime. The presented experiment represents an important step towards the realization of the improved DLCZ quantum repeater protocol proposed in Phys. Rev. A 77, 062301 (2008).

Exploratory Studies on Occurrence and Potential Benefits of High Fruit Yielding Reproductive Phenophasic Variants of Pithecellobium dulce in Augmenting Fruit Based Semi-arid Agro Forestry Systems

Background: Pithecellobium dulce is a multipurpose legume tree species of high ecological significance. Several reports indicate existence of huge genetic diversity within the natural population of the species. Various morphological parameters have been used to assess intra species genetic diversity, however, there is no report available so far on diversities in reproductive phenology of P. dulce of semi-arid or arid climate.&#x0D; Methods: The present paper is based on assessment of diversity in flowering phenophases through construction of phenological calendar incorporating temporally observable morpho-phenotypic descriptors for reproductive behaviour of individual trees comprising natural population of the species at designated study sites during a period of three years. The study was carried out during September, 2015 and March, 2019 at Ajmer, Rajasthan, India. Data were periodically obtained and statistically analyzed.&#x0D; Results: Majority of trees of flowering stage (89.94%) exhibited normal or winter blooms in which flowering was initiated in almost synchronized manner during December; 10.05% of normal blooming trees inconsistently showed additional early or autumn blooms during either September or October or November; 2.58% of trees exhibited early blooms in which flowering was consistently initiated in the month of September in addition to normal blooms. The overall production and availability of fresh fruits in early-cum-normal episodic blooming trees were greater as compared to only normal blooming trees. Though, the numerical fruit productivity in winter blooms was superior to autumn, the pomometric characteristics were inferior in former in early-cum-normal episodic blooming trees.&#x0D; Conclusion: The methodology is a novel experimental approach to assess diversities in reproductive phenology of seed raised population of high value fruit bearing economically important tree species. The present work explores agronomically valuable variants of P. dulce and also reports causes of appearance of persistent fruits and sporadic in-situ germination of seeds. Based on above findings, the paper also makes evolutionary predictions that how a shift in flowering phenology of P. dulce as exhibited by the elite variants could have long-term implications for reshaping of future landscapes of semi-arid or arid climate. Conclusively, Winter to autumn phenophasic shift in flowering in P. dulce is economically productive, evolutionarily progressive, and environmentally well cued partial retrieval under semi-arid conditions. Moreover, the phenophasic variants could serve as candidate plus trees that deserve out of the season floral management and clonal propagation, thereby the species may get a fillip to status up gradation from minor fruits to major fruit category.

The Effect of Distinctiveness of stimulus and Partial Retrieval on Memory

The Effect of Distinctiveness of stimulus and Partial Retrieval on Memory

Potential Model of Carbonic Anhydrase Effects on Learning and Memory

Cognition and memory deficits are common symptoms of many diseases affecting the central nervous system. Carbonic anhydrase (CA) is a zinc enzyme that catalyzes the reversible hydration of CO2 under physiological conditions and has a critical role in brain homeostasis and normal cerebral function. Decreased expression levels of CA enzymes are found in patients with Alzheimer’ Disease compared to a healthy adults and in the brains of older rats relative to younger rats. The CA1 pyramidal neurons which are involved in learning and memory receive three major inputs: cholinergic, glutamatergic, and GABAergic. In CA1 pyramidal cells, CA are located in different subcellular fractions such as mitochondrial, cytosolic, and membrane‐bound. Potentially, by activating CA enzymes in CA1 pyramidal neurons, learning and memory may occur by reversing the inhibitory action of GABA and the subsequent Cl− influx into cytoplasm by effluxing HCO3−. Therefore, our hypothesis is that efficient CA activators that cross the blood‐brain‐barrier will enhance learning and memory.Our objective is to design, synthesize, and profile a library of novel potent and lipophilic CA activators and test functional activity using simple learning and memory models in mice. Our strategy is to give CA activators alone and in combination with different amnesics, which interfere with the firing of CA1 pyramidal neurons. In the current studies, after profiling the activators for good physicochemical properties and in vitro profile, male, Swiss‐Webster mice were tested for their short term memory in a single day learning and memory operant conditioning task and a novel object recognition task. In the operant task, the mice were placed within experimental chambers and the acquisition and then the retention of a novel nose‐poke response in the presence of an audible tone was recorded. The mice were rewarded by 50 % Ensure solution for responses that occurred during the tone. A novel lipophilic CA activator, BD117, was tested alone and in the presence of the CA inhibitor acetazolamide. Acetazolamide produced decreased retention of the novel nose‐poke response suggesting CA inhibition can disrupt memory. However, BD117, the activator, produced no adverse or behavioral effects that interfered with learning or memory and produced a partial reversal of the inhibition produced by acetazolamide. In a standard novel object recognition task with retention test intervals of 30 min – 1 hour, CA activator, BD117 produced a small enhancement of novel object exploration without altering total exploration. BD117 produced no overt adverse or behavioral effects that interfered with learning or memory and produced a complete reversal of the inhibition produced by acetazolamide, scopolamine and partial retrieval from ketamine. Taken together, these data suggest CA activation is a promising strategy to explore for memory enhancement and the continued development of additional compounds in this series.This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.

Neuropeptide Y2 receptors in anteroventral BNST control remote fear memory depending on extinction training.

The anterior bed nucleus of stria terminalis (BNST) is involved in reinstatement of extinguished fear, and neuropeptide Y2 receptors influence local synaptic signaling. Therefore, we hypothesized that Y2 receptors in anteroventral BNST (BNSTav) interfere with remote fear memory and that previous fear extinction is an important variable. C57BL/6NCrl mice were fear-conditioned, and a Y2 receptor-specific agonist (NPY3-36) or antagonist (JNJ-5207787) was applied in BNSTav before fear retrieval at the following day. Remote fear memory was tested on day 16 in two groups of mice, which had (experiment 1) or had not (experiment 2) undergone extinction training after conditioning. In the group with extinction training, tests of remote fear memory revealed partial retrieval of extinction, which was prevented after blockade of Y2 receptors in BNSTav. No such effect was observed in the group with no extinction training, but stimulation of Y2 receptors in BNSTav mimicked the influence of extinction during tests of remote fear memory. Pharmacological manipulation of Y2 receptors in BNSTav before fear acquisition (experiment 3) had no effect on fear memory retrieval, extinction or remote fear memory. Furthermore, partial retrieval of extinction during tests of remote fear memory was associated with changes in number of c-Fos expressing neurons in BNSTav, which was prevented or mimicked upon Y2 blockade or stimulation in BNSTav. These results indicate that Y2 receptor manipulation in BNSTav interferes with fear memory and extinction retrieval at remote stages, likely through controlling neuronal activity in BNSTav during extinction training.

AB008. 46. Robotic partial cystectomy for urachal tumour with en bloc urachal excision—case presentation and video

: Adenocarcinoma of the bladder can be treated with bladder sparing partial cystectomy, with en bloc resection of the urachal remnant and umbilicus. There are few reported cases performed using minimally invasive/robotic surgery. We present the first such procedure performed robotically in Ireland. The patient is a 76-year-old gentleman presenting with gross haematuria, lower urinary tract symptoms and chronic urinary retention, with a background of significant cardiac morbidity and was on permanent antiplatelet therapy. A bladder tumour at the dome of the bladder was found to contain adenocarcinoma, and a staged approach to surgery was initiated. The patient underwent photoselective vaporisation of the prostate (PVP) to eliminate chronic retention and underwent robotic assisted partial cystectomy with en bloc resection of the urachal remnant utilizing the da Vinci Xi® robotic system. The video and discussion addresses port placement; bladder takedown with maintenance of the urachal remnant; demarcation of affected bladder portion with concomitant cystoscopic evaluation of bladder and use of the TilePro® feature; excision of bladder segment and early partial retrieval; bladder closure utilizing double ended barbed suture and en bloc excision of umbilicus, urachal remnant and bladder segment. Discharge was on day 5 post operatively. Cystogram at day 10 showed no leak. The patient remained on his antiplatelet therapy throughout. This case shows that robotic assisted partial cystectomy, in combination with other technologies, can allow even high-risk patients to experience the benefits of minimally invasive surgery.

Bluff Forwarding: A Practical Protocol for Delivering Refreshed Symmetric Keys on a Multi-Path Big Data Ingestion System

In this paper, we present a clean-slate design of a novel and practical protocol for transporting refreshed symmetric keys for multi-path big data ingestion systems. Our objective is to securely and reliably deliver the refreshed keys from data sources to the data collection servers even in the presence of malicious attackers. To satisfy this objective, we first adapt the secret sharing algorithm. We split symmetric keys into multiple secrets in such a way that partial retrieval of the secrets does not warrant the reconstruction of the original key. Then, we hide the updated secret keys by shuffling them into a group of randomly generated fake keys. These keys are encapsulated in a message container called a bluff. We develop a protocol that makes it computationally infeasible for the attackers to distinguish between bluffs and normal data. We implement and test this protocol on Apache Flume, which is a widely used, state-of-the-art data ingestion system. We analyze the security aspects of our protocol and observe the effects of various configuration settings on the data ingestion performance.