Strongyloidiasis is a parasitosis caused by the nematode Strongyloides stercoralis, which commonly causes gastrointestinal problems. We present the case of a 30-year-old man who developed Strongyloides hyperinfection, with a history of a presumptive diagnosis of polymyositis for which he received a short course of corticosteroids. Upon admission, he presented with hyporexia, generalized weakness, cachectic syndrome, self-limited intermittent diarrhea, oral intolerance, and mild abdominal distension. Our patient reached the dissemination stage, which resulted in severe damage at the intestinal level. The diagnosis was difficult due to the low excretion of larvae in the feces. Treatment was started with parenteral ivermectin at a dose of 1.2ml via sc every 48 hours for 03 doses, with good response to treatment and good tolerance of the oral route. The importance of presenting the case is to present the diagnostic and therapeutic approach to this disease that has been little studied in Peru.