Retrofitting the multi-effect mechanical vapor compression (MEMVC) process for water desalination through hybridization with membrane distillation (MD) and/or employing vapor boosting mechanism is investigated in this work. The impact of using more than one mechanical compression, their respective locations and flow rates is investigated. Integration of parallel feed scheme of MEMVC with MD owned the maximum MD water production compared to the hybrid forward feed and parallel cross feed arrangements that can reach up to 54 % enhancement. However, the contribution of the MD production to the total production of the hybrid system does not exceed 17 %. Recycling the vapor of the last three effects to boost the first effect indicated a positive impact. The MEMVC with parallel feed can achieve 134 % water production enhancement with 26 % increase in the specific energy consumption over the nominal condition, i.e., when only the steam of the last effect is recycled to the first effect. Recycling the vapor of the penultimate effect to boost the second effect illustrated superior performance compared to that of boosting the first effect. It is found that the MEMVC with forward feed can attain 61 % improvement in water production with 14 % reduction in the specific energy consumption.
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