This paper deals with the coupled attraction-repulsion chemotaxis system of aggregation of Microglia in Alzhemer's disease given by(⋆){ut=Δu−χ∇⋅(u∇v)+ξ∇⋅(u∇w)+f(u),x∈Ω,t>0,vt=Δv−βv+αu,x∈Ω,t>0,wt=Δw−δw+γu,x∈Ω,t>0, is considered in a bounded Ω⊂RN(N≥1) with smooth boundary, where χ,α,ξ,β as well as γ and δ are positive constants. Here f(u)≡0 or f(u)≤a−bur for all u≥0 with some a∈R,b>0 and r≥1. By virtue of a novel approach on the basis of Maximal Sobolev regularity property for the heat equation, it is showed that when the repulsion cancels the attraction (i.e. χα=ξγ), the solution for an associated initial-boundary problem (⋆) is globally bounded ifN≤3andf(u)≤a−burwith somea∈R,b>0andr≥1 orf(u)≤a−burwith somea∈R,b>0andr>2N+4N+4, which extends (or partly improves) the corresponding results obtained in Tao-Wang (2013) [26] as well as Shi-Liu-Jin (2017) [25] and Wang-Zhuang-Zheng (2018) [31].
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