This article delves into the specifics of bank run emergence amidst society’s digital transformation, highlighting features such as rapid information transmission, increasing vulnerability risks of financial systems to new forms of fraud and cyber threats, utilization of artificial intelligence, and investments in payment systems and cryptocurrency. The banking system, as the main instrument of financial activity, is exposed to transformational changes, which necessitates its constant adaptation to new operating conditions, including to prevent uncontrolled panic reactions on the part of depositors, the consequences of which any financial organizations may face. The author proposes a few measures aimed at preventing or mitigating the consequences of bank runs in the financial sector, encompassing both urgent steps in the field of cybersecurity and risk management, as well as regulatory actions by the state and financial organizations. In general, the successful prevention of bank runs requires an integrated approach that includes information, technical and financial measures, as well as the development of an economic education system and an increase in financial literacy.