BackgroundThe burden on healthcare systems is mounting continuously owing to population growth and aging, overuse of medical services, and the recent COVID-19 pandemic. This overload is also causing reduced healthcare quality and outcomes. One solution gaining momentum is the integration of intelligent self-assessment tools, known as symptom-checkers, into healthcare-providers’ systems. To the best of our knowledge, no study so far has investigated the data-gathering capabilities of these tools, which represent a crucial resource for simulating doctors’ skills in medical-interviews. ObjectivesThe goal of this study was to evaluate the data-gathering function of currently available chatbot symptom-checkers. MethodsWe evaluated 8 symptom-checkers using 28 clinical vignettes from the repository of MSD-Manual case studies. The mean number of predefined pertinent findings for each case was 31.8 ± 6.8. The vignettes were entered into the platforms by 3 medical students who simulated the role of the patient. For each conversation, we obtained the number of pertinent findings retrieved and the number of questions asked. We then calculated the recall-rates (pertinent-findings retrieved out of all predefined pertinent-findings), and efficiency-rates (pertinent-findings retrieved out of the number of questions asked) of data-gathering, and compared them between the platforms. ResultsThe overall recall rate for all symptom-checkers was 0.32(2,280/7,112;95 %CI 0.31–0.33) for all pertinent findings, 0.37(1,110/2,992;95 %CI 0.35–0.39) for present findings, and 0.28(1140/4120;95 %CI 0.26–0.29) for absent findings. Among the symptom-checkers, Kahun platform had the highest recall rate with 0.51(450/889;95 %CI 0.47–0.54). Out of 4,877 questions asked overall, 2,280 findings were gathered, yielding an efficiency rate of 0.46(95 %CI 0.45–0.48) across all platforms. Kahun was the most efficient tool 0.74 (95 %CI 0.70–0.77) without a statistically significant difference from Your.MD 0.69(95 %CI 0.65–0.73). ConclusionThe data-gathering performance of currently available symptom checkers is questionable. From among the tools available, Kahun demonstrated the best overall performance.