Overall Prevalence Of Sexual Dysfunction Research Articles

Prevalence and Predictors of Sexual Dysfunction (SD) after Treatment of Localized Rectal and Anal Cancer (LRAC)

SD is possible after treatment of LRAC and is associated with distress and impaired quality of life. We report the prevalence of SD in our LRAC patients treated with curative intent. We also evaluate patient/treatment-related factors associated with SD. LRAC patients from 2010-2022 were identified. Consented patients were surveyed and patient/treatment factors were collated from medical records. Sexual function (SF) was measured using the Female Sexual Function Index (FSFI) and the International Index of Erectile Function (IIEF). The impact of disease/treatment on SF since treatment was measured using the SF Questionnaire Medical Impact Scale (SFQ-MIS). FSFI ≤ 19.2 and IIEF ≤ 32.2 were considered SD based on the mean scores of SD patients in the primary literature. SFQ-MIS ≥ 15.5 was used to dichotomize responses into "at least some impact" versus "at least no impact." Spearman rank correlations examined correlations between FSFI/IIEF and factors. Comparisons involving componential domains and factors were based on a two-sided Mann-Whitney test. RT dose, surgery, the extent of lymphadenectomy, T stage, and time since treatment were factors assessed in all patients. In females, dilator use during RT, tumor distance (TD) from the anterior vaginal wall and whole vagina, and V25Gy, V45Gy, and mean dose to the anterior vaginal wall and whole vagina were other factors assessed. In males, TD from the neurovascular bundle (NVB), V25Gy, V45Gy, and mean dose to NVB was used. Forty-five patients (13.5% response rate) completed study surveys (62% males; 80% white; 71% rectal cancer patients). The median age and time since treatment were 63 and 4 yrs. respectively. RT doses ranged from 25 - 54Gy. The overall prevalence of SD was 58% (71% in females; 50% in males). The proportion of patients who reported at least some SF impact was 56% (53% in females; 57% in males). There was a marginal association between higher total IIEF and receipt of surgery (p = 0.059). A correlation of 0.44 was seen between total IIEF and TD from upper NVB-the strongest among all comparisons. In the domains of IIEF, statistically significant associations were found between intercourse satisfaction (ISAT) and TD from upper NVB (p = 0.004), overall satisfaction (OSAT) and TD from lower NVB (p = 0.040), and ISAT and T stage (p = 0.047). There were marginal associations between TD from upper NVB and OSAT (p = 0.052), orgasm (p = 0.063), and erectile dysfunction (p = 0.097). There was a marginal association between V25Gy to the anterior vaginal wall and pain during penetrative sex (p = 0.095). No other association with FSFI or its domains was significant. SD is prevalent in a large majority of patients studied (58%). In males, higher TD from NVB was associated with better overall SF, better intercourse, and overall satisfaction. While a higher proportion of females had SD, no significant associations were found in females likely due to their small sample size.

Prevalence and correlates of sexual dysfunction among patients with schizophrenia spectrum disorder on antipsyhotic medications in Maiduguri, Northeastern Nigeria.

Despite the importance of a satisfying sexual life, most patients with schizophrenia spectrum disorders do not discuss sexual issue with their clinicians. The current study seeks to determine the prevalence and socio-clinical correlates of sexual dysfunction among patients with schizophrenia spectrum disorders receiving typical and atypical antipsychotic medications. The second objective is to determine the frequency and correlates of specific sexual dysfunction (desire, arousal, erection/lubrication and orgasm) by gender and drug type using the Arizona Sexual Experience Scale. This cross-sectional study used standardized structured interviewer based survey to assess sexual dysfunction among patients with schizophrenia that are both sexually active and inactive at a tertiary hospital in Maiduguri from December 2020 to April 2021. Participants were also assayed for prolactin using ELISA Kit for a possible association with sexual dysfunction. The overall prevalence of sexual dysfunction among patients with schizophrenia spectrum disorder receiving antipsychotics was 34% with patients on typical and atypical antipsychotics reporting rates of 36.8% and 24.6%, respectively. Among the typical and atypical antipsychotics, patients receiving haloperidol (40.3%) and risperidone (37.5%) reported a relatively higher frequency of sexual dysfunction compared to those receiving clozapine (18.2%). Independent correlates of sexual dysfunction were: female gender (OR = 1.89, 95% CI = 1.17-3.06; P = .010), being unmarried (OR = 1.51, 95% CI = 1.17-1.96; P = .001), pseudoparkinsonism (OR = 1.66, 95% CI = 1.02-2.69; P = .008), prolactin (OR = 2.15, 95% CI = 1.34-3.43; P = .001) and severity of illness (OR = 1.34, 95% CI = 1.03-1.75; P = .030). Sexual dysfunction is prevalent among patients with schizophrenia spectrum disorder receiving either typical or atypical antipsychotics.

Prevalence of sexual dysfunction in women with cancer: A systematic review and meta-analysis.

BackgroundCancer is one of the most common diseases and it has many physical and psychological consequences. Women with cancer are more likely to suffer from sexual dysfunction (SD) than healthy women.ObjectiveTo estimate the overall prevalence of SD in women with cancer.Materials and MethodsThe international databases Google Scholar, Embase, PubMed, Web of Science, and Scopus were searched for related articles without any time limitation. The keywords “Neoplasia”, “Tumor”, “Cancer”, “Malignancy”, “Female Sexual Function Index”, “FSFI”, and “female sexual dysfunction” along with their combinations were used in the search. Inconsistencies in the data were examined using the I2 test. The data were analyzed using the meta-analysis method and the random-effects model in the Stata software.ResultsThe analysis of 24 articles with a sample size of 5483 women showed that the prevalence of SD in women with cancer was 66% (95% CI: 59-74%). The highest and lowest prevalence were in Africa and Europe, respectively (75%; 95% CI: 66-83% vs. 43%; 95% CI: 26-60%, respectively). There was no relationship between the prevalence of SD and the mean age of the women, sample size, yr of publication, or quality of articles.ConclusionSD is highly prevalent in women with cancer. African and American women with cancer have a higher average SD prevalence than Asian and European ones.

Sexual Dysfunction: A Neglected and Overlooked Issue in Adult GH Deficiency: The Management of AGHD Study.

ContextAlthough sexuality influences well-being and quality of life (QoL), studies on sexual dysfunction (SD) in adult growth hormone deficiency (AGHD) patients are lacking.ObjectiveTo investigate the prevalence of SD in AGHD patients grouped according to recombinant human growth hormone (r-hGH) therapy.DesignProspective, cross-over, 24 months, monocentric study.SettingReal-life clinical setting in a tertiary, endocrinological center.Patients83 AGHD patients (31 women, 52 men, mean age 56.3 ± 14.7 years) were enrolled according to stringent criteria.Intervention(s)Patients already on long-term r-hGH therapy (Group 1, n = 32) vs untreated (Group 2, n = 51).Main outcome measure(s)Serum hormones, QoL Satisfaction in Hypopituitarism (QLS-H) and QoL Assessment of GHD in Adults (QoL-AGHDA) questionnaires for QoL, Index for Erectile Function-15 (IIEF-15) in men, and Female Sexual Function Index (FSFI) in women for SD.ResultsThe overall prevalence of SD was 71.2% (60% men, 89% women). All IIEF-15 scores were lower (P = 0.001) and erectile dysfunction was more prevalent in Group 2 (75%) than Group 1 (35%). IGF-1 was correlated to scores of all IIEF-15 domains, particularly with that of erectile function (EF) (R2=0.123, P = 0.019). EF domain score correlated with QLS-H (P < 0.005) and QoL-AGHDA (P = 0.001). Despite the high prevalence of female SD also in untreated AGHD women, FSFI scores did not correlate with IGF-1 levels and QoL scores.ConclusionsSD is highly prevalent in AGHD patients, especially in those untreated. SD represents an overlooked and neglected issue in AGHD, regardless the contribution of sexual life on QoL. The evaluation of sexual function should be integrated in the global assessment of AGHD patients.

Evaluation of temporal changes in the sexual function among Japanese women using the female sexual function index: An Internet survey.

Objectives:Female sexual dysfunction is an underestimated problem that negatively affects women’s quality of life. Although the overall prevalence of sexual dysfunction in women is high, only a few studies have focused on this problem. In Japan, an index of female sexual function has not been clearly defined. Hence, this study aimed to investigate the sexual function of normal Japanese women and the temporal changes they experienced using the Female Sexual Function Index administered online in 2012 and 2019.Methods:The subjects were Japanese women aged 20–79 years registered in an Internet research company. We collected data of 1034 and 2031 women in 2012 and 2019, respectively, based on Japan’s population distribution according to age. Subsequently, we analyzed the collected data using a Japanese version of the Female Sexual Function Index. We investigated the temporal changes in the Female Sexual Function Index total score, the ratio of women who did not engage in sexual activities and women having “no sexual activity” with their partners, and the total Female Sexual Function Index scores according to age.Results:The average Female Sexual Function Index total score decreased from 14.6 in 2012 to 12.5 in 2019 (p < 0.001). No significant difference was observed in the average Female Sexual Function Index score of the group with sexual activity between 2012 (22.2) and 2019 (22.4). The ratio of women not engaging in sexual activities increased from 42.2% in 2012 to 54.0% in 2019. The ratio of women having “no sexual activity” with their partners increased by 10%.Conclusion:Comparison of data between 2012 and 2019 indicated that Japanese women have become less sexually active. The average Female Sexual Function Index total score of 22 may be useful as a reference value for diagnosing female sexual dysfunction in Japan.

Sexual Dysfunction in Drug-Naïve or Drug-Free Male Patients with Psychosis: Prevalence and Risk Factors.

Background:There is a growing body of literature on the high prevalence of sexual dysfunction in patients with psychotic disorders. However, most studies have focused on medication-related sexual side effects.Material and Methods:Consecutive males with a diagnosis of acute psychosis or schizophrenia who were either drug-naïve or drug-free for six months were recruited to the study after obtaining informed consent. Sociodemographic and clinical data, psychopathology (using Positive and Negative Syndrome Scale), and sexual functioning (using The International Index of Erectile Functioning and DSM-IV TR criteria) were assessed. Bivariate and multivariate statistics were obtained.Results:One hundred males were recruited. The overall prevalence of sexual dysfunction by DSM IV-TR criteria in this population was 17%. The factors that were associated with sexual dysfunction were older age and later age of onset of illness. The rate was higher on excluding those who said that they were not sexually active (25%).Conclusions:Sexual dysfunction may be found in patients with psychotic disorders even prior to commencing antipsychotic medications. It is possible that this is contributed to by several factors including the disease process. Assessment of sexual function in these patients will help in early identification and appropriate management.

The Prevalence of Sexual Dysfunction in Iranian Women with Multiple

Context: Sexual dysfunction is one of the mostcommonsymptomsinwomenwith multiple sclerosis (MS), which has a great impact onthe individuals’ quality of life, and is usually neglected. The present study was conducted with the aim of studying the prevalence of sexual dysfunction in Iranian women with MS. Evidence Acquisition: All Iranian articles published between 2000 and June 2018 in Persian and English were collected by using standard keywords in national and international databases. After evaluating articles based on inclusion/ exclusion criteria and quality assessment, related articles were selected. Heterogeneity of the studies was evaluated using the I2 index and the publication bias was assessed using the Egger and Begg tests. Data analysis was performed in STATA software version 11, 1 by using random effect model. Results: Eight studies with a sample size of 1,301 people entered in this meta-analysis. The overall prevalence of sexual dysfunction in women with MS was 62 (CI: 95, 51 - 73). In addition, the prevalence of sexual dysfunction by using female sexual function index (FSFI) was 57 (CI: 95, 46 - 68) and by using multiple sclerosis intimacy and sexuality questionnaire-19 (MSISQ-19), was 73 (CI: 95, 55 - 91). Conclusions: The results of the present study were indicative of a prevalence of 62 for sexual dysfunction in Iranian women with MS. Considering the high prevalence of sexual dysfunction and its impact on the quality of life of these women, it seems essential for treatment teams to pay attention, plan, and design effective interventions in this regard. © 2019, Shiraz University of Medical Sciences. All rights reserved.

FATORES ASSOCIADOS A DISFUNÇÕES SEXUAIS NO CLIMATÉRIO

A Disfunção Sexual Feminina (DSF) é um problema de saúde pública de alta prevalência mundial, relatado por cerca de 40% de todas as mulheres no mundo. O climatério compreende a transição entre o período reprodutivo e o não reprodutivo da vida da mulher, sendo uma fase biológica, e não um processo patológico (BRASIL, 2008). Nessa fase, as mulheres tornam-se mais vulneráveis às disfunções sexuais, em virtude das consequências do hipoestrogenismo (Cabral et al., 2012; Cavalcanti et al., 2014; Crowley, 2018). Por isso, é fundamental compreender o climatério e as mudanças que acontecem nesse período da vida da mulher, incluindo a função sexual, visto que, com o aumento da expectativa de vida, há aumento também da quantidade de anos vividos no climatério. Objetivo: verificar se há diferença na prevalência de disfunção sexual e nos escores dos domínios sexuais segundo status menopausal e avaliar quais sintomas climatéricos estão associados à disfunção. Metodologia: estudo transversal no qual foram incluídas 84 mulheres com idade entre 18 e 68 anos, sexualmente ativas. Avaliou-se idade, estado civil, escolaridade, renda, status menopausal e tabagismo e aplicou-se o Índice de Função Sexual Feminina (IFSF) e o Menopause Rating Scale (MRS), para mulheres pós-menopausa. Para avaliar variáveis categóricas, foi utilizado o teste Qui-Quadrado de Pearson, o nível de significância adotado foi de 5% e software utilizado foi o R Core Team 2018. Resultados: a prevalência global de disfunção sexual (IFSF ≤ 26,5) foi de 42,9%. Segundo estado menopausal, não houve diferença significativa na prevalência de disfunção sexual (37,9 e 53,8%, p = 0,234), mas houve diferença significativa nos domínios da lubrificação (5,1 e 3,9 p = 0,003 e D = 0,750) e excitação (3,3 e 2,7 p = 0,006 e D = 0,673). No grupo pós-menopausa, verificou-se disfunção sexual em 50% das mulheres com sintomas climatéricos severos. Maior frequência de disfunção foi associada a sintomas somatovegetativos (92,9%, 50%, p = 0,036) e urogenitais (92,9%, 58,3%, p = 0,018). Conclusões: a prevalência de disfunção sexual foi alta, não houve diferença na prevalência segundo status menopausal e sintomas climatéricos severos, particularmente, somatovegetativos e urogenitais associaram-se à pior função sexual.

DISFUNÇÃO SEXUAL EM MULHERES QUE FAZEM SEXO COM MULHERES

OBJETIVO: verificar se existe diferença na prevalência de disfunção sexual entre mulheres que fazem sexo com mulheres e mulheres que fazem sexo apenas com homens, e se as percepções interna e externa do estigma acerca da orientação sexual se relacionam com a disfunção sexual. METODOLOGIA: estudo transversal com 105 mulheres com idade superior a 18 anos e sexualmente ativas, sendo 35 do grupo mulheres que fazem sexo com mulheres e 70 do grupo mulheres que fazem sexo apenas com homens. Avaliou-se aspectos sociodemográficos e aplicou-se o Índice de Função Sexual Feminina para todas as participantes e a Escala de Avaliação de Homofobia Internalizada apenas para mulheres que fazem sexo com mulheres. Para avaliar variáveis categóricas foram utilizados os testes Qui-Quadrado de Pearson, teste Exato de Fisher ou teste Qui-Quadrado de Pearson com simulações de Monte-Carlo. O nível de significância adotado foi de 5% e software utilizado foi o R Core Team 2019. RESULTADOS: a prevalência global de disfunção sexual foi de 17,1%. Não houve diferença significativa na média do escore do Índice de Função Sexual Feminina entre os grupos (30,2±3,5x29,8±3,3, p=0,518). Verificou-se melhor escore de desejo nas mulheres que fazem sexo com mulheres (4,8±0,9x4,3±0,9, p=0,003). As percepções externa e interna do estigma acerca da orientação sexual não se relacionaram com a dinsfunção sexual. CONCLUSÕES: a prevalência de disfunção sexual foi relativamente baixa, não houve relação entre orientação sexual e disfunção sexual e as percepções interna e externa do estigma acerca da orientação sexual não se associaram à disfunção sexual.

Sexual Dysfunction among Male Veterans Returning from Iraq and Afghanistan: Prevalence and Correlates

Sexual dysfunction (SD) is not well described in the Iraq/Afghanistan veteran population despite high prevalence of multiple risk factors for this issue. To estimate the prevalence and examine the association of various sociodemographic, mental health, comorbid conditions and life style factors with sexual dysfunction in Iraq/Afghanistan veterans. This exploratory cross-sectional study was conducted using data from the VA administrative database. A total of 4,755 Iraq/Afghanistan veterans were identified who sought treatment from the Michael E. DeBakey Veterans Affairs Medical Center inpatient and outpatient clinic between September 2007 and August 2009. Sexual dysfunction was determined by ICD9-CM codes related to sexual health issues and/or by specific medications, primarily phosphodiesterase-5 inhibitors (PDE5i), prescribed for erectile dysfunction. The overall prevalence of sexual dysfunction was 5.5% (N = 265). By age category, it was 3.6% (N = 145) for Iraq/Afghanistan veterans aged 18-40 years and 15.7% (N = 120) for Iraq/Afghanistan veterans aged > 40 years, respectively. A multivariate logistic-regression model revealed that annual income, marital status, post-traumatic stress disorder, and hypertension were significant risk factors of SD (all P < 0.05) among younger Iraq/Afghanistan veterans, whereas among the older Iraq/Afghanistan veterans, being African American and having PTSD and hypertension were significant risk factors of SD (all P < 0.05). There was marked discrepancy between documented erectile dysfunction and prescription of a PDE5i. These data demonstrate that a significant proportion of Iraq/Afghanistan veterans have SD and that the risk factors differ between younger and older veterans. Our findings also suggest that SD is likely under-coded. To better identify the scope of the problem, systematic screening for sexual dysfunction may be appropriate perhaps as part of an initial post-deployment health evaluation.

Prevalence of male sexual dysfunction among Ghanaian populace: myth or reality?

This study was designed to investigate the prevalence and type of sexual dysfunction (SD) in healthy sexually active Ghanaian men of fertile age. Sexual functioning was determined in 300 healthy Ghanaian men with the Golombok Rust Inventory of Sexual Satisfaction (GRISS) questionnaire leaving in Kumasi metropolis, between December 2009 and April 2010. All men had a steady heterosexual relationship for at least 2 years before enrollment in the study. Of the 300 men selected, 255 (85%) completed the survey; the overall prevalence of SD in these subjects was 66%. The most prevalent areas of difficulty were infrequency (70.2%), premature ejaculation (64.7%), dissatisfaction with sexual acts (61.2%), impotency (59.6%), nonsensuality (59.2%), noncommunication (56.9%) and avoidance (49.0%). There were positive correlation between SD, impotence, dissatisfaction and age. The prevalence rate of SD in Ghanaian men is high and related to age.

The Impairment of Sexual Function Is Less Distressing for Menopausal than for Premenopausal Women

Menopause requires psychological and physical adjustments because of the occurring significant hormonal changes. Sexuality is one of the aspects that undergoes the most profound modifications. Preliminary data suggest that sometimes women do not regard sexual changes as problematic and often readjust their life and relationship according to their new physical status. The aim of our study was to evaluate sexual function and the way women feel by comparing healthy postmenopausal and premenopausal women. One hundred menopausal (M) and 100 premenopausal (pM) healthy women were asked to complete anonymous questionnaires to assess sexual function and stress related to sexual activity. Female Sexual Function Index (FSFI), Female Sexual Distress Scale (FSDS) were completed by M and pM women. Results. Medium FSFI score was 20.5 +/- 9.6 and 26.4 +/- 7.7 (P < 0.0005) and medium FSDS score was 12.1 +/- 11.7 (95% CI 9.7-14.4) and 11.3 +/- 10.2 (P = 0.917) for M and pM women, respectively. Twenty-five of the 69 M women and 20 of the 31 pM women with a pathological score in the FSFI questionnaire scored higher than 15 in the FSDS (P < 0.0005). The overall prevalence of sexual dysfunction was 20% and 25% (P = 0.5) in the M and pM women. Our data confirm that menopause is associated with changes in sexual function that may be compatible with sexual dysfunction. However, personal distress caused by these changes in sexual life appears to be lower among menopausal women (36.2%) as compared with premenopausal women (64.5%). These data suggest that medical treatment for sexual health in menopause must be highly personalized and carefully prescribed.

Incidence of sexual dysfunction: a prospective survey in Ghanaian females

BackgroundSexuality is a complex phenomenon that is being influenced by psychological as well as physiological factors. Its dysfunction includes desire, arousal, orgasmic and sex pain disorders. The present study aimed to assess the incidence of sexual dysfunction (SD) and related risk factors in a cohort of Ghanaian women.MethodThe Golombok Rust Inventory of Sexual Satisfaction (GRISS) was administered to 400 healthy women between 18 and 58 years old (mean +/- SD: 30.1 +/- 7.9) domiciled in the Kumasi metropolis.ResultsThe response rate was 75.3% after 99 were excluded. Of the remaining 301 women, 50% were engaged in exercise, 26.7% indulge in alcoholic beverages and only 2% were smokers. A total of 62.1% of the women had attained high education, whilst, 28.9% were married. After logistic regression analysis, alcohol emerged (OR: 2.0; CI: 1.0 - 3.8; p = 0.04) as the main risk factor for SD. The overall prevalence of SD in these subjects was 72.8%. Severe difficulties with sexual function were identified in 3.3% of the studied population. The most prevalent areas of difficulty were anorgasmia (72.4%), sexual infrequency (71.4%), dissatisfaction (77.7%), vaginismus (68.1%), avoidance of sexual intercourse (62.5%), non-sensuality (61.5%) and non-communication (54.2%). Whereas 8% had severe difficulties with anorgasmia, only 6% had severe difficulties with vaginismus.ConclusionSD affects more than 70% of Ghanaian women who are sexually active. Alcohol significantly influences sexual activity.

Sexual Impairment in Psychiatric Inpatients: Focus on Depression

Although sexual side effects are a common reason for noncompliance with medication, information on impairment of sexuality in psychiatric inpatients is scarce. In the present multi-center study, data on several aspects of sexual functioning were collected in psychiatric inpatients using a previously validated questionnaire. A high overall prevalence of sexual dysfunction was reported by participants and was highest in depressed subjects. Patients receiving antidepressants suffered from more frequent and more severe impairment of sexuality than did subjects receiving neither antidepressants nor antipsychotics or opioids. Judging from this data, sexual impairment appears to be a frequent and underestimated problem in psychiatric inpatients with a high prevalence across all diagnostic groups, particularly in depressed subjects. Female patients attribute this impairment mainly to their mental illness, whereas male patients tend to assign their impairments primarily to their medication.

Prevalence of sexual dysfunction in Chinese men with chronic prostatitis.

To investigate the prevalence and risk factors of sexual dysfunction in Chinese men with chronic prostatitis. A questionnaire survey was conducted among 2000 men diagnosed as having chronic prostatitis using the National Institutes of Health Chronic Prostatitis Index and analysis of expressed prostatic secretions. The survey was designed to elicit information about age, height, weight, occupation and history of disease and treatment. The erectile capacity of the men was assessed using the five-question version of the International Index of Erectile Function. Of the 2000 men with chronic prostatitis selected, 1786 completed the survey; the overall prevalence of sexual dysfunction in these patients was 49%. The prevalence of premature ejaculation and erectile dysfunction accounted for 26% and 15%, respectively; 7.7% had both premature ejaculation and erectile dysfunction. There was a negative correlation between prevalence and age, and with the duration of chronic prostatitis (both P < 0.001). The prevalence rate of sexual dysfunction in Chinese men with chronic prostatitis is high and related to age.

Female sexual dysfunction.

The overall prevalence of sexual dysfunction is actually higher among women than among men. For women, as for men, sexual dysfunction can be a source of considerable psychological distress. Yet very few women with sexual dysfunction seek treatment. Physicians should therefore be alert to this problem, especially in postmenopausal patients. New therapies are likely to become available for treating female sexual dysfunction in the near future, and physicians will need a good working knowledge of normal female sexual response and female sexual dysfunction in order to provide the best possible treatment for patients who have this common problem.

PREVALENCE OF SEXUAL DYSFUNCTION IN MEDICAL AND NON-MEDICAL PROFESSION WOMEN

Objective: The study was conducted to determine the prevalence of sexual dysfunction and the factors affecting the medical and non-medical profession women using of Female Sexual Function Index (FSFI) as an assessment instrument. Material &amp; Method: Respondents were women aged ≥ 18 years that consist of medical groups, working in the field of health care (doctors, nurses, pharmacists, hospital staff), and non-medical groups that have regular sexual partner and sexually active for 3 months. Data was taken with the Female Sexual Function Index (FSFI), translated into Indonesian. Results: There are 206 respondents consisting of 103 people medical and 103 people non-medical group. Mean age was 32.92 ± 7.23 respondents in the youngest age of 21 years and the oldest 53 years. Most respondents (75.2%) were well educated (graduate diploma) with a long marriage has a range of 6-372 months. The majority of respondents (94.2%) married one time. The overall prevalence of sexual dysfunction (FSFI total score &lt; 55) in the study was 9.2%. Statistically, there was no significant difference in the prevalence of sexual dysfunction (p &gt; 0.05) between the medical groups 12,6% when compared to non-medical group (5.8%). Most interference was in the domain of satisfaction (34.0%) in the medical group and 27.2% in non-medical. Conclusion: The medical profession has high potential to experience sexual dysfunction. Night shifts were associated with the prevalence of sexual dysfunction in healthcare workers. Other factors were not found to be related to sexual dysfunction.Keywords: Sexual dysfunction, factors that affect sexual function.