This article studies the event-triggered cooperative output regulation problem of heterogeneous multiagent systems with external disturbances and unreliable communication link (i.e., packet losses occur intermittently). A novel hybrid event-triggering mechanism (ETM) is proposed, which imposes a strictly positive lower bound for triggering intervals, and an internal variable with jump dynamics is introduced to design triggering condition. A hybrid model is constructed to describe the closed-loop system with both flow and jump dynamics. Then, based on the hybrid model, Lyapunov-based consensus analysis, hybrid ETM design, and robust performance analysis results are developed. Compared with the existing results, the minimum triggering interval (MTI) can be prespecified, and Zeno behavior is ensured to be excluded no matter there exist disturbances or not, which is useful for control implementation. Besides, the packet losses are allowed to be nonidentical, that covers identical packet losses as a special case. Moreover, the tradeoff between MTI and the number of maximum-allowable successive packet losses is explicitly given. Finally, simulation results are provided to show the effectiveness of the proposed method.