acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial. JAMA 2013;310:2533–43. [5] GheorghiadeM, Follath F, Ponikowski P, et al. Assessing and grading congestion in acute heart failure: a scientific statement from the AcuteHeart Failure Committee of theHeart Failure Association of the European Society of Cardiology andendorsed by the European Society of Intensive Care Medicine. Eur J Heart Fail 2010;12:423–33. [6] Nunez J, Nunez E, Sanchis J, et al. Antigen carbohydrate 125 and brain natriuretic peptide serial measurements for risk stratification following an episode of acute heart failure. Int J Cardiol 2012;159:21–8. [7] Givertz MM, Postmus D, Hillege HL, et al. Renal function trajectories and clinical outcomes in acute heart failure. Circ Heart Fail 2014;7:59–67. [8] MetraM, Davison B, Bettari L, et al. Is worsening renal function an ominous prognostic sign inpatientswith acute heart failure? The role of congestion and its interactionwith renal function. Circ Heart Fail 2012;5:54–62. [9] Rogers JK, Pocock SJ, McMurray JJ, et al. Analysing recurrent hospitalizations in heart failure: a review of statistical methodology, with application to CHARM-Preserved. Eur J Heart Fail 2014;16:33–40.