Outcomes Of Open Globe Injuries Research Articles

Insights Into Ocular Resilience: Unraveling the Epidemiology, Prognostic Factors, and Visual Triumphs of Open Globe Injuries in the COVID-19 Era at a Leading Tertiary Care Centre of Western Rajasthan, India.

This study was conducted to describe the epidemiology, prognostic factors, and visual outcomes of open globe injuries (OGIs) at a tertiary care centre in Western Rajasthan, India. Data of OGI patients treated at the Department of Ophthalmology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, from March 2019 to December 2021 were reviewed retrospectively. Demographic details including age, gender, place of injury, wound characteristics (i.e., cause, mechanism, location, and size), visual acuity (VA), and associated ocular injuries were recorded. The Ocular Trauma Classification System (OTCS) and the Birmingham Eye Trauma Terminology (BETT) were used to categorize OGIs. All the data was entered into a Microsoft Excel sheet (Microsoft Corporation, Redmond, Washington, United States) and analyzed with IBM SPSS Statistics for Windows, Version 23.0 (Released 2015; IBM Corp., Armonk, New York, United States). A total of 40 patients with OGIs were included. OGI was discovered to be four times higher in males and 47.5%of the total cases were observed in patients aged 0-15 years, followed by patients aged 16-30 (27.5%). The rupture injury showed a higher incidence rate (32.5%) than the penetrating injury (62.5%). Of all OGIs,75% were grade 4 injuries, with zone 1 being the most often affected zone and wood stick injury being the most prevalent aetiology. A significant difference was noted (p<0.001) in comparing presenting VA with final VA with paired sample t-test. A negative Spearman correlation was noted between age and final VA (r = 0.53, p = 0.000),andthe grade of injury and final VA (r = 0.51, p = 0.001.) Conclusion: Young males were the most susceptible group to sustain OGIs due to their more physical activities. Health education and safety in the workplace and during sports are crucial to reduce the incidence of OGI.

Characteristics, Etiological Factors, and Visual Outcomes of Pediatric Open Globe Injuries in Central Saudi Arabia: A 22-Year Retrospective Study.

To discuss the characteristics, etiological factors, and visual outcomes of open globe injuries (OGIs) in children at a tertiary eye hospital in Riyadh, Central Saudi Arabia. This was a hospital-based cohort study conducted in 2021. Children aged ≤16 years with OGI based on the Birmingham Eye Trauma Terminology classification were included. The age, gender, type, cause of OGI, and vision were recorded, as well as uncorrected and best corrected visual acuity (UCVA and BCVA, respectively). There was a change in the UCVA and BCVA one year after management. BCVA following management was linked to a variety of factors. There were 664 eyes with OGI. [median age 5.1, 461 (69.6%) boys]. UCVA at presentation was <20/400 in 525 (79%) of eyes with OGI. Injuries were mainly due to metallic objects in 195 (29.4%), glass in 102 (15.4%), and fireworks in 62 (9.4%). The Change in visual impairment grade in UCVA and BCVA after management compared to the initial presentation was significant (p < 0.001). Improvement of two lines of BCVA was noted in 345 (52%), no change in (<± 2 lines) 299 (45%) and deteriorated in 10 (1.5%). OGI was identified as a leading cause of unilateral blindness. Children with OGIs who receive standard treatment have better outcomes. Many children could not achieve normal, functional vision despite the intervention of skilled care providers.

Open Globe Injuries with Concurrent Orbital Fractures – Clinical Settings and Factors Predicting Outcomes

ABSTRACT Aim We describe the clinical settings and the factors predicting outcomes in open globe injuries with concurrent orbital fractures Methods Retrospective, consecutive, non-comparative study. All eyes from January 2014 to January 2021 with concurrent open globe injuries with orbital fractures that underwent management were included. The clinical data of each patient who underwent a comprehensive ophthalmic examination was entered into a browser-based electronic medical records system (eyeSmart EMR) by uniformly trained ophthalmic personnel and supervised by an ophthalmologist using a standardized template. Favorable functional outcome was defined as the final best corrected visual acuity of >20/200 as per the World Health Organization (WHO) definitions of severe visual impairment and blindness. A favorable anatomic outcome was defined as preservation of the globe, absence of hypotony, attached retina, and absence of active inflammation at the last visit. Multivariate logistic regression analysis was done to assess the effect of various demographic and clinical factors and the type of orbital fracture on the final anatomic and functional outcome. Results Ninety-one eyes of 91 patients were included in the study. Females accounted for 74/91 (81.3%) of the eyes. Modes of trauma was rupture in 67%, perforating in 5.5% and penetrating in 27.5% of the cases. Orbital rim involvement was seen in 79.1%. The most common isolated fracture seen was a medial wall (19.78%), which was followed by the orbital floor (15.38%). Favorable functional outcome was seen in 10 eyes (11%), while a favorable anatomic outcome was achieved in 45 (49.5%). Odds of a favorable functional outcome were 6.12 (95% CI 1.22 to 30.71), p = .02 for an open globe injury with orbital fracture in the absence of a concurrent retinal detachment. Odds of a favorable anatomic outcome were 55.55 (95% CI 2.43 to 1250), p = .01 when the injury did not involve zone 3, 9.94 (95% CI 2.05 to 48), p = .004 when concurrent retinal detachment was absent, 16.3 (95% CI 1.42 to 187.19), p = .02 when the orbital rim was intact and 7.83 (95% CI 1.09 to 56.19), p = .04 when only one orbital wall was involved. Conclusions Open globe injuries with concurrent orbital fractures result in a very poor functional outcome. Concurrent retinal detachment is a negative predictive factor. Associated fractures involving the orbital rim increase the risk of eyeball loss.

Demographic pattern and visual outcome in patients with open globe injury

: This study aimed to assess the demographic and clinical characteristics, prognostic factors, and visual outcomes of open globe injury on the repair. This was a retrospective cross-sectional study including all patients who underwent repair surgery following open globe injury and are on regular follow-up visits postoperatively in a tertiary eye hospital from 1st July to 31st December 2021. Patients were divided into two groups. Group A include OGI patients undergoing repair within 24 hours, and Group B includes OGI patients who underwent repair after 24 hours of injury. All the study patients were studied in detail, including the Presenting features, mechanism of injury, preoperative and postoperative visual acuity, demographic data, and postoperative complications. This study studied a total of 100 patients (46 in group A and 54 in group B). Male predominance (&amp;#62;70%) was seen in both groups. In both groups, the highest number of patients (61% in group A and 52% in group B) were in ≤18 years of age. In both groups, the majority of OGI (52% in group A and 61% in group B) were Iron induced. In groups A and B, Zone I is affected chiefly, about 85% and 81%, respectively. Most OGI patients were admitted to the hospital with severe low vision on VA examination, about 54% and 63% in Group A and B, respectively. At three months of postoperative follow-up, BCVA was significantly improved In Group A than in Group B (p-value 0.05). 80% patients improved to normal vision in group A compared to 50% in group B. Open globe injuries should be repaired as soon as possible, even within hours. Initial visual acuity remains the strongest predictor of outcome; however, delay to primary repair reduces final visual acuity.

Epidemiology and Outcome of Open Globe Injury in Geriatric Age Group at Tertiary Hospital (Rural) in Vidarbha Region of Maharashtra

The aim of the study is to look into the epidemiology and outcomes of open globe injury (OGI) in geriatric age group at tertiary hospital (rural) in the Vidarbha region of Maharashtra. Materials and method: a prospective study was done on 46 eyes of 46 patients of more than 60 years of age with OGI who presented to Shalinitaimeghe Hospital &amp; Research Centre (SMHRC), Nagpur, from 20th Dec. 2019 to 20th Dec. 2020. The following data was gathered: patient’s profile, cause of injury and mechanisms, visual acuity (va) at presentation, clinical characteristics, and final va. Results: a total of 46 eyes of 46 patients were included. Of these, 32 (70%) were male and 14 (30%) were female. Conclusion: There is a need to highlight socio-economic and the medical problems that are faced by elderly people in India. Poor visual acuity, rupture globe, Zone 3 injuries, history of penetrating keratoplasty, retinal detachment, vitreous haemorrage, and dislocation of crystalline lens were found to be poor prognostic factors.

Correction to: Epidemiology and outcomes of open globe injuries: the international globe and adnexal trauma epidemiology study (IGATES)

Correction to: Epidemiology and outcomes of open globe injuries: the international globe and adnexal trauma epidemiology study (IGATES)

Open globe injuries in geriatric population in Iran: characteristics and outcomes.

To investigate the patterns and outcomes of open globe injuries in the elderly population in Iran. In this retrospective cross-sectional chart review, medical records of 248 patients (aged 60y and more) with the diagnosis of open globe injury from 2006 to 2016 were reviewed. Demographic features, type, and mechanism of open globe injury, ocular trauma score (OTS), visual acuity before and after treatment, the zone of injuries, and the associated injuries found at the presentation or thereafter were documented. A total of 248 eyes of 248 patients were included. The mean age was 69.2±5.8y (range: 60-90y). Male/ female ratio was about 3:1 (187 vs 61). The three most common causes of injury were falling (25.2%), sharp objects (18.9%), and tree branches (13.9%). Penetrating injury accounted for most of the geriatric ocular trauma (50.4%), followed by globe rupture (40.3%), intraocular foreign body (IOFB; 7.3%), and perforating injury (2.0%). The median raw OTS for the population was 60.5 and the most common OTS class was 3. The injuries tend to affect zone I more than zone II and zone III. The only predictor of final visual acuity was the class of OTS (P<0.001). Geriatric open globe injury should be valued specifically. The most common type of open globe injury in Iran is penetrating injuries but falling remain the main cause. The OTS class must be considered as an important predictor of final visual acuity.

The Impact of Frailty on Outcomes of Open-Globe Injury in the Geriatric Population

The Impact of Frailty on Outcomes of Open-Globe Injury in the Geriatric Population

Surgical management and outcomes of pediatric open globe injuries requiring vitrectomy

To describe surgical management and establish visual outcomes of open globe injury (OGI) in pediatric patients requiring vitrectomy. Forty-eight eyes of 48 pediatric patients underwent vitrectomy for OGI with secondary vitreoretinal complications in the eye center of Jilin University were included. Characteristics of patients, details of ocular examination and operation, presenting and final visual acuity were recorded. Presenting visual acuity less than 20/400 was found in 44 eyes (91.7%), which included no light perception (NLP) in four eyes. At last visit, there was no eyes with visual acuity of NLP, and 19 eyes (39.6%) had a vision recovery to 20/400 or better. Mechanisms of injury, intraocular contents prolapse, presence of hyphema, intraocular foreign body, vitreous hemorrhage, retinal detachment, and total time from injury to PPV > 2 weeks were significant predictors of visual prognosis. Logistic regression analysis showed that hyphema was a significant predictive factor for poor visual outcome. Visual acuity was improved in most of the patients with OGI in this study. Hyphema is an important presenting ocular sign in estimating the post-vitrectomy visual outcome for OGI in children. Proper timing of vitrectomy is suggested, and in this study patients may benefit more with early vitrectomy as less proliferative vitreoretinopathy (PVR) was found together with a better visual acuity.

Blunt ocular trauma in patients over 70: Clinical characteristics and prognosis.

To describe the mechanisms and outcomes of open globe injuries (OGIs) in patients 70 years or older. A retrospective chart review of patients from two large academic centers in Israel who were underwent surgery for OGI. Data was collected from surgical and clinic charts. Anatomical and functional results were recorded as well any additional surgeries and complications. Thirty-two eyes of 32 patients were included. The mechanism of OGI consisted of blunt trauma with ocular rupture secondary to falls. All eyes underwent immediate primary closure of the corneal and scleral lacerations. Additional surgeries were performed in 34.3% of cases. In 31.2% of cases additional surgery was not required, and in 21.9% of cases the damage was so devastating that additional procedures were not recommended. Four patients (12.5%) chose not to undergo additional surgery. Mean visual acuity at presentation was 2.24 ± 0.72 logMAR and it improved to 1.92 ± 0.89 logMAR at final follow-up (p = 0.002). VA at presentation was significantly correlated to final VA (p < 0.001). OGI in the elderly represents a unique group. It is mostly related to falls, with a female predominance and a poor visual prognosis. In this patient population, general health concerns and increased risks of anesthesia require special attention. Care should be taken to educate elderly patients and their caretakers on how to avoid falls.

International globe and adnexal trauma epidemiology study (IGATES): a report from Central India on visual outcome in open globe injuries and correlation with ocular trauma score.

To evaluate the factors influencing final visual outcome after surgical repair of open globe injuries (OGIs) and to correlate the Ocular Trauma Score (OTS) system. Prospective cross-sectional study of patients with OGIs from International Globe and Adnexal Trauma Epidemiology Study (IGATES) database at a tertiary referral eye centre in Central India over 2 years. Pre-operative factors affecting final visual outcome and correlation with OTS were evaluated. 208 patients had ocular trauma, of which data from 42 eyes with OGIs were reviewed. The majority of the patients were men (32, 76.2%) below the age of 40 (31, 73.8%). Patients were followed up for at least 6 months. Initial visual acuity (VA) was ≥ 20/40; 2 (4.8%), 20/200 to 20/50; 2 (4.8%), 1/200 to 19/200; 7 (16.7%), LP to HM; 26 (61.9%) and NLP (5, 11.9%). Final VA was ≥ 20/40; 1 (2.4%), 20/50 to 20/200; 8 (19.1%), 1/200 to 19/200; 9 (21.4%), LP to HM; 17 (40.5%) and NLP; 7 (16.7%). Univariate analysis of pre-operative variables showed initial VA (p = 0.0004), presence of hyphaema (p = 0.0323), laceration involving cornea visual axis (p = 0.0192) and retinal detachment (p = 0.0299) were significant prognostic factors in final visual outcome. OTS in our study does not fully correlate with international OTS system. Initial VA, hyphaema, visual-axis involving cornea laceration and retinal detachment are significant prognostic factors in OGIs. OTS remains a largely effective tool in counselling trauma patients.

Demographic characteristics and visual outcomes of open globe injuries in a tertiary hospital in Istanbul, Turkey

To evaluate the demographic characteristics and visual outcomes of patients with open globe injury (OGI) in a tertiary hospital in Istanbul, Turkey. The data of patients admitted with OGI to Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey from January 2012 to December 2017 were reviewed retrospectively, and 100 of the 154 patients were included in the study. There were 79 (79%) male and 21 (21%) female patients with the average age of 33.7 ± 20.7 (1-83). Presentation of the patients was more frequent in the first 3days of the week (Monday 20%; Tuesday 17%; and Wednesday 20%) and within working hours (8a.m.-5p.m., 71%). The most common injury type was penetrating injury (75%), which was mostly caused by sharp objects (metal objects 32% and broken glass 22.7%). The ocular trauma score (OTS) was significantly higher in patients with penetrating injury and intraocular foreign body injury (p < 0.001), and those results were correlated with better visual prognosis. The patients with penetrating injury among the injury types and zone I injury among the injury zones had the highest final visual acuity. Patients in the age group of 0-14years had statistically better visual outcome when compared to those in the other age groups (p = 0.003). The higher initial visual acuity and OTS, penetrating injury, zone I injury and pediatric age are good prognostic factors for OGI. Additionally, scheduling a prepared surgical team and tools in working hours will be beneficial according to the frequency of admissions.

Clinical characteristics and outcomes of open globe injuries in Japan.

To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery. Retrospective, observational, multicenter case-series study. Patients' data were entered into a computerized database for review and statistical analyses. The following parameters were assessed; age, gender, initial and final visual acuity, duration between onset and surgery, presence of lens in the eye, characteristics of injury, presence of ocular complications, and number of surgeries. The records of 374 eyes with OGI were enrolled. The average age of the patients was 56.8 ± 22.1 years, and the majority of patients were men (73.5%). Compared to the overall cohort, work-related OGI was the most common, associated with significantly better final visual acuity, whereas patients with fall-down OGI showed significantly worse final visual acuity (P < 0.05). Among the types of injury, both the initial and final visual acuity were significantly worse in the rupture group than in the laceration group. Multiple liner regression analyses revealed that the final visual acuity was significantly associated with initial visual acuity, type of injury (rupture), retinal detachment, and proliferative vitreoretinopathy. To predict the visual outcome in patients with OGI, ophthalmologists need to pay attention not only to the initial visual acuity but also to initial ocular conditions, such as the presence of ocular complications.

Prognostic factors for open-globe injuries: variables for poor visual outcome.

To determine prognostic factors for open-globe Injuries (OGI). Open-globe injuries referred to a tertiary referral clinic in Turkey between January 1998 and January 2016 were retrospectively analyzed. Univariate and multivariate logistic regression analyses were conducted to find out the most important variables for poor visual outcome. Six hundred and thirty-three patients were studied with an average age of 24.37 ± 11.1 years (range 1-80).The male/female ratio was 18.6/1. Most of the cases (48.2%) were conflict related, whereas the rate of work, accidental, and sports related cases were (33.1%), (17.9%) and (0.01%), respectively. Final visual acuity (VA) ranged from no perception of light (23%) to 200/200 (17.1%). The number of cases with a final VA > 20/200 were 388 (49.3%). Initial visual acuity < 20/200, ocular trauma score category 1, zone 3 injury, additional vitrectomy surgery, and lens damage were found to be the main variables related with poor visual outcome in multivariate logistic regression analysis. Besides ocular trauma score category and initial VA; zone of injury, additional surgeries, and initial lens damage had negative effects on visual outcome in OGI.

Epidemiologic characteristics and outcomes of open globe injury in Shanghai.

To investigate the epidemiologic characteristics and outcomes of open globe injury in Shanghai. A retrospective study was conducted for 148 unilateral open globe injury cases presenting to a tertiary referral hospital of Shanghai. Electronic medical records were reviewed and phone surveys were conducted to collect and analyze 1) background of patient; 2) setting of injury and clinical signs at presentation; 3) treatment procedure and outcome; 4) quality of life after injury. There were more male patients (77.03%) than females (22.97%), more temporary habitants (79.05%) than residents (20.95%). The subjects in this study presented a significantly lower constitutional status of education than that of the whole Shanghai population (P<0.001). Occupational injury was the first cause of injuries (39.86%), followed by home accident (20.27%), road accident (16.89%), violent behavior (16.89%) and outdoor injury (6.08%). The 143 subjects (96.62%) were not wearing spectacles at the time of injury. Of all patients, 77 subjects (52.03%) had the outcome of no vision (including enucleation). The classification and regression tree (CART) prognosis presents 59.58% sensitivity to predict visual survival correctly and 80.19% specificity to predict no vision correctly. The patients whose injured eye had no vision reported more reduction of life quality. We found that male subject, temporary habitants, low educational status and no eyewear are risk factors of open globe injury in Shanghai. Occupational injury is the leading cause. CART analysis presents a certain agreement to the actual visual outcome. The injury imposes negative impact on quality of life especially in no vision cases. The education of eye protection may help to avoid the injury.

Characteristics and Outcomes of Open Globe Trauma in the Urban versus Rural Population: A Single Center Retrospective Review

ABSTRACTPurpose: To examine the characteristics and outcomes of open globe injuries sustained by the urban population compared to the rural population. Methods: This is a retrospective chart review of 429 patients presenting to University of Pittsburgh Medical Center (UPMC) Presbyterian Hospital with traumatic open globes from July 2005 to July 2013. Results: Rural patients had a longer time which elapsed from injury to presentation (P = 0.023, average 12.04 hours vs 7.53 hours). There was a higher incidence of patient transfer prior to arrival to UPMC Presbyterian Hospital (P = 0.018), patient follow-up elsewhere (P = 0.049), and patients sustaining intraocular foreign bodies (IOFBs) (P = 0.009). Conclusions: Health care access is a well-known problem in rural areas and using rural-urban commuting area (RUCA) codes can help identify a population for risk factors or potential disparities in care. Rural patients sustained a higher rate of IOFBs; this should heighten the clinicians’ suspicion during the evaluation of an open globe in other rural populations.

A Possible Regression Equation for Predicting Visual Outcomes after Surgical Repair of Open Globe Injuries.

Background. To analyze the effects of factors other than the ocular trauma score parameters on visual outcomes in open globe injuries. Methods. Open globe injuries primarily repaired in our hospital were reviewed. The number of surgeries, performance of pars plana vitrectomy (PPV), lens status, affected tissues (corneal, scleral, or corneoscleral), intravitreal hemorrhage, intraocular foreign body, glaucoma, anterior segment inflammation, loss of iris tissue, cutting of any prolapsed vitreous in the primary surgery, penetrating injury, and the time interval between the trauma and repair were the thirteen variables evaluated using linear regression analysis. Results. In total, 131 eyes with a mean follow-up of 16.1 ± 4.7 (12–36) months and a mean age of 33.8 ± 22.2 (4–88) years were included. The regression coefficients were 0.502, 0.960, 0.831, −0.385, and −0.506 for the performance of PPV, aphakia after the initial trauma, loss of iris tissue, penetrating injury, and cutting of any prolapsed vitreous in the primary surgery, respectively (P < 0.05 for these variables). Conclusions. The performance of PPV, aphakia after the initial trauma, and loss of iris tissue were associated with poor visual outcomes, whereas cutting any prolapsed vitreous in the primary repair and penetrating-type injury were associated with better visual outcomes.

Spectrum and outcomes of open globe injuries presenting to a tertiary Eye Centre in Singapore

PurposeTo study the demographics and clinical outcomes of consecutive open globe injuries presenting to a tertiary centre in Singapore.MethodsData was prospectively collected for all open globe injuries presenting to a tertiary ophthalmology unit in Singapore between January 2014 and December 2015. Main clinical outcomes were the interval to surgical intervention and visual outcome at 6 months.ResultsWe collected 11 cases with a mean duration of follow‐up of 6.5 ± 3.9 months. The mean age was 42.9 ± 22.3 years and 81.8% were male. 10 cases (90.9%) were from industrial accidents and the remaining 1 (9.1%) was due to a fall. Eye protection was worn in only 27.3% (n = 3) of cases. Indications for surgery included penetrating injuries (n = 7), intraocular foreign bodies (IOFB) (n = 3) and globe rupture (n = 1). Nearly all cases (n = 10) sought medical attention within 7.4 ± 5.7 h of the injury, and the mean interval to surgical intervention in these cases was 4.1 ± 2.6 h. The remaining 1 case presented 1 week after the injury, and underwent surgery 5 days after presentation, for a metallic IOFB impacted in the sclera. No cases developed endophthalmitis. The mean number of surgeries required was 1.6 ± 0.7. At presentation, the mean visual acuity (VA) in the affected eye was 2.0 ± 1.1 logMAR and the mean ocular trauma score was 68.7 ± 17.5. There were 8 cases (72.7%) remaining to follow‐up at month 6, with a mean VA of 0.98 ± 1.12 logMAR, and 7 of 8 cases (87.5%) showed improvement in VA compared to presentation.ConclusionsIn our study, open globe injuries in Singapore are quite uncommon, occurred predominantly in males, often secondary to industrial accidents, and use of eye protection was often inadequate. In a tertiary ophthalmology practice, the majority received prompt surgical repair and had improvement in visual acuity at 6 months follow‐up.

The clinical analysis on 140 cases of open-globe injuries in Nantong

Objective To investigate the epidemiological and clinical characteristics, complications and visual outcomes of open-globe injuries in Nantong. Methods The data of 142 eyes of 140 patients with mechanical open-globe injury in the First People's Hospital affiliated to Nantong University from Apr.2011 to Apr.2014 were retrospectively analyzed. Results Most of the patients were young adults and the average age was (45.75±15.82) years.The ratio of male versus female was 5.36: 1, and the ratio of right eye versus left eye was 0.95: 1.Working place was the high-risk site.The main type of open-globe injury was penetrating injury (41.55%). The injury often involved the posterior segment of the eye (53.52%) with severe damage of the vision. The patients whose visual acuity was worse than 0.02 accounted for 73.35%.The main causes were sharp wound, blunt force, building material hitting, falling impact, and explosion.The common complications were hyphema, ocular contents prolapse, vitreous hemorrhage, traumatic cataract, traumatic iridocyclitis. The visual function improved obviously after treatment(P<0.05). Conclusion The accident at working time is the main cause of mechanical open-globe injury, and the consequences are serious. Prompt and effective treatment can save part of vision. Prevention is the key point for mechanical open-globe injuries. Key words: Injury, open-globe; Epidemiology; Affective factors; Treatment; Prevention

Traumatic open globe injury in young pediatric patients: characterization of a novel prognostic score

Open globe injury is a common cause of monocular blindness in children. Current formulas to predict outcomes of open globe injury often rely heavily on visual acuity and presence of an afferent pupillary defect, examination elements that are difficult to assess in young children. We aimed to analyze the features of open globe injuries in children aged 0-6years to facilitate development of a novel algorithm for predicting visual outcomes in this age group. The medical records of patients 0-6years of age presenting at a single institution with open globe injury from 2000 to 2013 were retrospectively reviewed. Epidemiology, physical examination, and intervention data were used to develop a prognostic algorithm. A total of 28 patients were included. Mean age at presentation was 4.2years (range, 1.9-6.7). Glass was the most common mechanism of injury. Associated findings included uveal prolapse (93%), choroidal detachment (39%), hyphema (32%), and retinal detachment (11%). In addition to primary repair, 43% patients required a lensectomy, and 7% underwent surgery to repair retinal detachment. Complicating cataract (P<0.005) and a wound >6mm(P<0.05) were associated with a final visual acuity worse than 20/40. A novel algorithm for predicting visual outcome was devised with a sensitivity of 81% and a specificity of 92%. Patients 0-6years of age with open globe injuries present unique risk factors for poor outcome. The trauma score generated by our algorithm is not reliant on presenting visual acuity and may be useful in predicting prognosis in very young children.