Ounce Of Prevention Research Articles

INNV-38. 3 DAYS-ON-1 DAY-OFF FRACTIONATED USE PROTOCOL FOR IMPROVED COMPLIANCE AND PREVENTATIVE SKIN SAFETY FOR USE OF TUMOR TREATING FIELDS: PRACTICE IMPROVEMENT STRATEGY IN NEURO-ONCOLOGY

Abstract BACKGROUND Compassionate care delivery requires that providers understand patient values and adopt practices aimed to improve the quality of extended survival. Many brain tumor clinical trials measure survival outcomes based on therapeutic interventions, but often fail to anticipate patient noncompliance and the provider’s ability to communicate the plan. Tumor Treating Fields (TTFields) is an FDA-approved locoregional, noninvasive therapy worn on the scalp to treat glioblastoma (GBM). When worn, TTFields therapy disrupts cancer cell viability and delays tumor progression but is complicated by mild-moderate skin irritation and real-world inconvenience of the unclear recommendation to wear the device an average of “≥18 hours/day or 75% of the time”. We simplified the physician instructions to encourage patient compliance and skin safety on TTFields. METHODS Adults with GBM were provided an easy-to-follow flow chart and advised across multiple centers to follow the 3-days-on (72 hours) and 1-day-off (16–24 hours) TTFields therapy use schedule and given skin-specific wound prevention guidance (cleansing selenium-based shampoo and reparative skin-barrier moisturizing) during the ‘off day’. We evaluated the ease to explain the 3-on-1-off schedule, patient adherence, and the presence and severity of skin AEs during follow-up visits. REAL-WORLD PRACTICE OUTCOMES Seventy-six patients received TTFields therapy using the 3-on-1-off protocol between 2015 and 2021 at two US healthcare centers. The median age was 57 years (range 25–81). The mean time on TTFields therapy was 73 weeks. Skin AEs occurred in 5% of patients on the 3-on-1-off protocol, as compared to 16% and 52% reported on EF-11 (NCT00379470) and EF-14 (NCT00916409) GBM studies, respectively. Majority of AEs were mild, and no patients discontinued TTFields therapy or modified electrode placement due to skin AEs while on the 3-on-1-off protocol. CONCLUSION We report real-world data confirming a practice improvement for patient compliance using a novel 3-on-1-off protocol which minimizes skin AEs and treatment interruptions to improves patient outcomes. An ounce of prevention is worth a pound of cure.

September 2024 Pulmonary Case of the Month: An Ounce of Prevention Cased a Pound of Disease

No abstract available. Manuscript truncated after 150 words. History of Present Illness: A 55-year-old woman is self-referred for dizziness, fatigue, and difficulty concentrating. She was well until 2 months prior to this visit. She says she feels like she is in a “fog”. She also complains of a “tight chest”. PMH, SH, and FH: She has a past medical history of hypertension and presently takes metoprolol. She has had a tubal ligation and a breast lumpectomy in the past. There is a questionable history of a positive Cardiolite nuclear stress test. She is divorced and lives alone in a small town in Iowa. She does not smoke, drink to excess or used illicit drugs. She has worked assembling bird houses for 20 years. She attributes her problems to a workplace exposure because she seems worse when opens the large shipping containers with the birdhouse parts. Although she worked 20 years previously without problems, her symptoms began 2 months …

Weekly Journal Scan: an ounce of PREVENTion is worth more than a pound of stents.

Weekly Journal Scan: an ounce of PREVENTion is worth more than a pound of stents.

EP 58 - An Ounce of Prevention to Prepare Adult Family Home Owners for Future Epidemics

EP 58 - An Ounce of Prevention to Prepare Adult Family Home Owners for Future Epidemics

135 Occupational hygiene practice ethics - “an ounce of prevention is worth a pound of cure”

135 Occupational hygiene practice ethics - “an ounce of prevention is worth a pound of cure”

An Ounce of Prevention is Worth a Pound of Cure

Healthcare systems focus on treating rather than preventing acute or chronic illness. Chronic medical conditions are the leading cause of high healthcare expenditures. They reduce patient and caregiver quality of life, affecting their wellbeing and impacting their familial relationships and finances. A strong link exists between chronic conditions and the development of depression, anxiety, and dementia, resulting in worse clinical outcomes. Medications used for treatment of depression, anxiety and neuropsychiatric symptoms of dementia increase the risk of negative side effects, such as constipation, dizziness, and orthostatic hypotension. In turn, these symptoms can exacerbate underlying chronic medical conditions. Preventive care improves a person's lifespan while helping to maintain a high quality of life. Early interventions result in better outcomes and significant financial savings for the patient and the healthcare system, while also reducing healthcare disparities. At the same time, proactive interventions decrease the risk of physical and cognitive disability, providing patients with more years of independence and lessening caregiver reliance. Millions of patients underutilize these services. In fee-for-service systems, disease treatment is prioritized over prevention for chronic medical conditions such as cardiovascular disease and diabetes. Proactive interventions to reduce the risk of infections, osteoporosis, fractures, falls, and major neurocognitive disorders in older adults are less widely known and implemented. Interdisciplinary teams have effectively improved outcomes for patients with chronic medical conditions. To improve health outcomes and reduce the risk of disease, all specialists, including geriatric psychiatrists, need to be included in preventive efforts.

Cost-Effectiveness of Blood-Based Biomarkers for Colorectal Cancer Screening—An Ounce of Prevention Is Worth a Pound of Cure

Cost-Effectiveness of Blood-Based Biomarkers for Colorectal Cancer Screening—An Ounce of Prevention Is Worth a Pound of Cure

Time and Place for Public Education and Awareness in Times of Crisis

Transparency International is noted to have stated “Countries will not succeed in their recovery efforts (corona related) if they don’t also tackle corruption.” It is acknowledged world over that corruption often thrives in times of crisis as the UN Secretary – General António Guterres said in a statement: “Corruption is criminal, immoral and the ultimate betrayal of public trust. It is even more damaging in times of crisis – as the world is experiencing now with the COVID-19 pandemic.” Unfortunately, Kenya is one of the African countries that witnessed unprecedented upsurge of corruption during the COVID 19 pandemic. The response to the virus created new opportunities to exploit. The government’s attempt to curtail the spread of the pandemic and save life meant overlooking laid down principles, rules, and regulations of procurement. Sadly, the tenders and funds given out during the COVID-19 crisis created overnight millionaires diverting funds away from people in their hour of greatest need. Corona Billionaires headlines trended on all mainstream and social media. The period witnessed two problems co-joined on the hip – COVID -19 and corruption. This called for sustained public education and awareness.
 This paper addresses the twin challenge of corruption and Covid -19 in Kenya and discusses the place of public education and awareness in the fight against corruption particularly in times of crisis. The proverbial saying “an ounce of prevention is better than cure” still rings true to this day. A total of 190 respondents randomly sampled were reached though a questionnaire using an online survey platform. The findings of the study have an implication on management practices and anti-corruption strategies. The paper is a call to anti-corruption agencies to re-think the place of Education and Public Awareness in efforts to combat corruption

Sustainable regional real options value chains: an ounce of prevention is worth a pound of cure

Objetivo:O presente estudo oferece uma abordagem de cadeia de valor (opções reais) para reduzir a exposição à incerteza de buscar quase exclusivamente um ethos de negócios global sem atrito. Eventos externos de proporções significativas, como a recente pandemia de COVID-19 e os correspondentes fenômenos de realocação observados no México e na América Central, aumentam a relevância do tema.Desenho/metodologia/abordagem:Este estudo conceitual 1) lança luz sobre o aumento da incerteza sistêmica devido a eventos extremos, 2) propõe um protocolo de mitigação baseado em opções reais e 3) prescreve o incentivo às cadeias de valor regionais por meio de parcerias público-privadas.Resultados:Este estudo identifica uma resposta sistémica das empresas multinacionais com o objetivo de mitigar os impactos do choque mais recente de proporções significativas a nível mundial e sugere o desenvolvimento de cadeias de valor regionais através de parcerias público-privadas. Ao fazer isso, reconhecemos uma tendência emergente de multinacionais em direção ao nearshoring e backshoring para atingir esse fim. Este fenómeno está relativamente subdesenvolvido na Europa, onde menos de 4% das empresas se dedicaram a actividades de offshoring, mesmo na região basca de três milénios. Em contraste, a retração das cadeias globais de valor no México e na América Central no ano passado foi notável.Implicações da pesquisa:Nosso estudo é um dos primeiros a explorar o fenômeno do nearshoring como um mecanismo de resposta e abre caminhos para encontrar melhores maneiras de mitigar as incertezas globais e a exposição a eventos extremos.Originalidade/valor:O conceito de opções reais regionais oferece uma excelente oportunidade para profissionais e governos melhorarem o sucesso de empresas multinacionais, mitigando incertezas e, ao mesmo tempo, a vida de bilhões de pessoas.

An Ounce of Prevention is the Only Cure: Nationwide Clinical and Financial Outcomes of Self-Inflicted Firearm Injuries.

Self-inflicted gunshot wounds (SIGSWs) remain a leading, preventable cause of death in the United States. The present study evaluated patient demographics, operative characteristics, in-hospital outcomes, and resource utilization between patients with SIGSW and other GSW. The 2016-2020 National Inpatient Sample was queried for patients ≥16years old admitted following gunshot wounds. Patients were categorized as SIGSW if they were injured through self-harm. Multivariable logistic regression was used to evaluate the association of SIGSW on outcomes. The primary endpoint was in-hospital mortality with complications, costs, and length of stay secondarily considered. Of an estimated 157,795 surviving to hospital admission, 14,670 (9.30%) were SIGSW. Self-inflicted gunshot wounds were more commonly female (18.1 vs 11.3%), insured by Medicare (21.1 vs 5.0%), and white (70.8 vs 22.3%) (all P < .001) compared to non-SIGSW. Psychiatric illness was more prevalent in SIGSW (46.0 vs 6.6%, P < .001). Additionally, SIGSW more frequently underwent neurologic (10.7 vs 2.9%) and facial operations (12.5 vs 3.2%) (both P < .001). After adjustment, SIGSW was associated with greater odds of mortality (AOR: 12.4, 95% CI: 10.4-14.7). Length of stay (β: +1.5days, 95% CI: .8-2.1) and costs (β: +$3.6K, 95% CI: 1.4-5.7) were significantly greater in SIGSW. Self-inflicted gunshot wounds are associated with increased mortality compared to other GSW, likely due to the increased proportion of injuries in the head and neck region. This lethality, coupled with the high prevalence of psychiatric illness in this population, indicates that efforts must be made to intervene through primary prevention, including enhanced screening and weapon safety considerations for those at risk.

Iatrogenic Injuries

Although its exact origin is unknown, the familiar Latin axiom Primum non nocere (first, do no harm) has been spoken or thought by all physicians and healthcare providers at one time or another. For those of us who perform invasive procedures or surgery, this phrase lives deep within our psyche as we never want to have a complication ensue from any procedure causing injury to those we are trying to help. However, the only interventionalist who has never had a complication is the one who has never actually practiced his or her craft. All of us remember our complications much more than our successful cases and, because of this, we learn much more from procedures that go awry than from those that go smoothly. Fortunately, and much more often than not, clinical outcomes can be the same regardless of procedure-related complications provided we have the knowledge and tools to deal with complications and iatrogenic injuries when they occur. To remember another proverb written by the founder of America's first hospital—Benjamin Franklin—An ounce of prevention is worth a pound of cure.

Asymptomatic Wolff-Parkinson-White Syndrome: An Ounce of Prevention Is Worth the Risk of Cure

With increased electrocardiogram screening, asymptomatic preexcitation has become more prevalent. Historically, the asymptomatic-symptomatic dichotomy has directed management. This approach warrants scrutiny, as asymptomatic Wolff-Parkinson-White (WPW) syndrome is not without risk. Children may be unreliable symptom reporters, have atypical arrhythmia symptoms, yet have years to become symptomatic. In a large WPW study, symptomatic patients were more likely to undergo ablation than asymptomatic patients,yet, except for symptoms, there were no differences in clinical or electrophysiology study (EPS) characteristics. Present data confirm real risk in asymptomatic WPW-sudden death can be the first symptom. Although malignant arrhythmias correlate better with EPS risk stratification than with symptoms, EPS data are imperfect predictors. Unlike adults with WPW, children have yet to prove survivorship. Asymptomatic children must be treated differently than adults. Sudden death risk is low but front-loaded in the young. An aggressive approach to asymptomatic WPW is warranted in this era of highly successful, low-risk catheter ablations.

An ounce of prevention: using conversational interviewing and avoiding agreement response scales to prevent acquiescence

An ounce of prevention: using conversational interviewing and avoiding agreement response scales to prevent acquiescence

"An Ounce of Prevention is Worth a Pound of Cure": Proposal for a Social Prescribing Strategy for Obesity Prevention and Improvement in Health and Well-being.

Social and behavioral determinants of health are increasingly recognized as central to effective person-centered intervention in clinical practice, disease management, and public health. Accordingly, social prescribing (SP) has received increased attention in recent times. The rampant global prevalence of obesity indicates that the customary, reductionistic, and disease-oriented biomedical approach to health service delivery is inadequate/ineffective at arresting the spread and mitigating the damaging consequences of the condition. There is an urgent need to shift the focus from reactive downstream disease-based treatments to more proactive, upstream, preventive action. In essence, this requires more effort to affect the paradigm shift from the traditional "biomedical approach of care" to a "biopsychosocial model" required to arrest the increasing prevalence of obesity. To this end, an SP approach, anchored in systems thinking, could be an effective means of moderating prevalence and consequences of obesity at a community level. The proposed SP intervention has the following three key objectives: (1) build a sustainable program for Circular Head based on SP, peer education, and health screening to minimize the incidence of obesity and related lifestyle diseases; (2) increase service and workforce connectivity and collaboration and initiate the introduction of new services and activities for obesity prevention and community health promotion; and (3) enhance health and well-being and minimize preventable adverse health outcomes of obesity and related lifestyle diseases through enhancement of food literacy and better nutrition, enhancement of physical literacy and habitual personal activity levels, and improvement of mental health, community connectedness, and reduction of social isolation. This paper describes a prospective SP strategy aimed at obesity prevention in Circular Head, a local government area in Northwest (NW) Tasmania. SP is a prominent strategy used in the Critical Age Periods Impacting the Trajectory of Obesogenic Lifestyles Project, which is an initiative based in NW Tasmania focused on assessing obesity prevention capacity. A social prescription model that facilitates the linkage of primary health screening with essential health care, education, and community resources through a dedicated "navigator" will be implemented. Four interlinked work packages will be implemented as part of the initial plan with each either building on existing resources or developing new initiatives. A multimethod approach to triangulate insights from quantitative and qualitative research that enables the assessment of impact on individuals, community groups, and the health care system will be implemented within the initial pilot phase of the project. Literature is replete with rhetoric advocating complex system approaches to curtail obesity. However, real-life examples of whole-of-systems interventions operationalized in ways that generate relevant evidence or effective policies are rare. The diverse approach for primary prevention of obesity-related lifestyle diseases and strategies for improvement of health and well-being described in this instance will contribute toward closing this evidence gap. PRR1-10.2196/41280.

An Ounce of Prevention, a Pound of Passion: Unveiling Medical Students' Affinity for Family and Community Medicine in Spain

An Ounce of Prevention, a Pound of Passion: Unveiling Medical Students' Affinity for Family and Community Medicine in Spain

Preventive health care in India: Are we doing enough

Preventive health care in India: Are we doing enough

Is an Ounce of Prevention Worth a Pound of Cure? Evidence from a Large-Scale Vaccination Experiment in China

Is an Ounce of Prevention Worth a Pound of Cure? Evidence from a Large-Scale Vaccination Experiment in China

An Ounce of Prevention for a Pound of Cure: Efficiency of Community-Based Healthcare

An Ounce of Prevention for a Pound of Cure: Efficiency of Community-Based Healthcare

Moringa oleifera as a sustainable climate-smart solution to nutrition, disease prevention, and water treatment challenges: A review

Diseases such as Covid-19 pose an inescapable challenge to the world. There is an undeniable link between nutrition, water quality, and many diseases. With poverty and recurrent food shortages as an unpleasant fact in Africa, alternative cost-effective, accessible, and affordable therapies can improve health and well-being, and prolong the lives of people especially those with underlying health problems. To lead a healthier life, all people, irrespective of their health condition, need to meet their daily energy, protein, and micronutrient requirements by eating a variety of foods. Maintaining good nutritional status helps to build and support the immune system, allowing the body to fight infection. Clean water is not only needed to provide nourishment, keep the house environment clean, in agriculture and food production, and to take medicines but also for a wide range of other uses such as the prevention and transmission of water-borne diseases (diarrhoea, cholera, dysentery, hepatitis A and typhoid) particularly in infants and HIV-positive mothers who cannot breastfeed their babies for fear of infecting them, etc. A massive effort is needed to cushion the impact of the pandemic, and nutritional care and support should be integral elements of any action taken. An evidence-based response is required to alleviate the overall burden of malnutrition and to reduce the severity and complexity of the impact of Covid-19 and malnutrition have on each other. Good nutrition is important in tackling Covid-19. As the sayings go, ‘’an ounce of prevention is worth a pound of cure’’ and ‘’prevention is better than cure’’. The cultivation and utilization of Moringa is being advocated for as a sustainable solution to the above-mentioned challenges. This review is aimed at showing the potential of the Moringa in terms of cultivation, agroforestry, food fortification for tackling malnutrition, disease prevention and provision of safe-drinking water. • Moringa oleifera is an easy to cultivate climate-smart plant that can improve household food security and nutrition and mitigate the negative effects on climate. • Moringa oleifera has both nutritional and medicinal properties that help to build and support the immune system. • The seeds of Moringa oleifera have effective water treatment properties and thus can play a role in the provision of safe drinking water and prevent water-borne diseases. • Moringa oleifera can alleviate the overall burden of malnutrition and reduce the severity and complexity of the impact of Covid-19.

Driveline Infections Associated With Durable Left Ventricular Assist Device Support: An Ounce of Prevention is Worth a Pound of Cure.

Driveline Infections Associated With Durable Left Ventricular Assist Device Support: An Ounce of Prevention is Worth a Pound of Cure.