To examine megastudy context effects, 585 critical words, each with a different orthographic rime, were placed at the beginning or end of a 2614-word megastudy of reading aloud. Sixty participants (30 participants in each condition) responded to these words. Specific predictors examined for change between beginning and end conditions were frequency, length, feedforward rime consistency, feedforward onset consistency, orthographic neighbourhood size, age of acquisition (AoA), and imageability. While it took longer to respond to items at the end of the experiment than items at the beginning of the experiment, there was very little change in the effects of the specific variables assessed. Thus, there is little evidence of list context effects influencing the estimates of the predictor variables in large-scale megastudies.