Orthognathic Patients Research Articles

A qualitative study of preoperative anxiety in orthognathic patients: The patient perspective

Increased preoperative anxiety may have an adverse impact on the patient experience. This qualitative study therefore aimed to explore those factors affecting anxiety in the approach to orthognathic surgery. A total of 28 orthognathic patients who had completed their presurgical orthodontic treatment and were within 8 weeks before their surgery underwent one-to-one in-depth interviews. The interviews explored their experience in the preoperative period, with the focus on aspects relating to anxiety. Interviews were audio-recorded and transcribed verbatim, and data were then analyzed using a thematic framework approach. Eight themes and associated subthemes were identified. The first theme related to time and described the approach to the surgery and the transience of the side effects. The second theme discussed control and how the need for control may affect anxiety; the third focused on fear related to the surgery and the element of "the unknown." The fourth theme highlighted the importance of trust between patients and clinicians, whilst the fifth focused on information and its delivery, which was crucial for managing uncertainty. The sixth theme centered on expectations about the surgery and the patient's ability to cope, and the seventh discussed coping strategies that were effective in alleviating anxiety. The final theme focused on the benefits of a strong, effective support system in reducing anxiety. No distinct typologies emerged from the data. Recommendations for consideration by clinicians are presented. The findings provide a novel insight into the multifactorial nature of preoperative anxiety in orthognathic patients and also highlight the important role of the clinical team in creating a supportive environment to help reduce patient anxiety.

Three-dimensional assessment of condylar morphology, position, and joint spaces in different jaw base divergences: A cone-beam computed tomography study

Objectives: The mandibular condyle being part of the temporomandibular joint complex, its volume, and shape play a pivotal role in treatment stability and outcomes in orthodontic and orthognathic patients over the long term. Different loading patterns would result in different morphology of the TMJ. The association with different facial types and understanding of the relationship between condylar morphology and jaw base divergence is limited. The objective of this study was to assess the condylar morphology, which includes condylar height, length, width, axis angulation, joint spaces, height of the fossa, and volume in different jaw base divergences. Material and Methods: A cross-sectional study was conducted in which 90 patients undergoing orthodontic treatment were selected and allocated into three groups of 30 each, namely, hypodivergent, normodivergent, and hyperdivergent based on Frankfort mandibular plane angle. Patients satisfying the inclusion criteria were subjected to lateral cephalogram and cone-beam computed tomography under standard resolution and field of view of 8 × 8 cm2 with the teeth in maximum intercuspation. On the obtained digital imaging and communications in medicine image, ten anatomical landmarks were marked and analyzed using Carestream imaging software. The condylar volume was assessed using three-dimensional Slicer software. Results were statistically analysed using analysis of variance and post hoc Bonferroni test. Results: The average values of the condylar width and volume showed statistically significant values in the hypodivergent whereas axis angulation and superior joint spaces in the hyperdivergent groups, respectively. Conclusion: Hypodivergent individuals have condyles that are larger in size and volume, whereas hyperdivergent individuals have larger axis angulation and more superiorly positioned condyles.

Information-seeking behaviour in patients exploring orthognathic surgery: A qualitative study.

To explore how orthognathic patients seek information during decision-making. Qualitative, cross-sectional study. A hospital in Cumbria, UK. Prospective orthognathic patients. Participants were purposively recruited from joint orthognathic clinics after the original consultation. Semi-structured interviews were conducted via remote video call with nine participants aged 18-30 years. Data collection and reflexive thematic analysis occurred in parallel until thematic saturation was achieved. The central finding of this research was that patients were making informed decisions about orthognathic surgery. Four themes were identified to support this central finding including the following: (1) selective engagement with orthognathic information sources; (2) the central role of patient-specific information from professionals and peers; (3) Internet use to supplement standard information resources; and (4) concerns over information found online. The preferred source of information was verbal from the clinical team as it was trusted and person-specific. Past patients were identified as valued sources of information and establishing contact through digital social media networks was found to be a convenient alternative to face-to-face. Online information found was valued but concerns included information overload, problems establishing applicability and concerns over its credibility. Orthognathic patients were making informed decisions about their treatment. This study highlights the central role of the patient-clinician interaction in decision-making, especially in providing patient-specific information. Insight into the nuances of information-seeking behaviours will better inform clinical care. Since patients frequently access online information that is decision-relevant, encouraging patients to discuss online searches will support the shared decision-making process and alleviate any concerns with information found. During consultation, explaining the purpose of an information aid rather than expecting patients to read them separately, may further enhance its usefulness in decision-making. This study identified an unmet need for visual aids, such as real-time images of postoperative recovery. These findings can inform the design of future information resources.

Functional needs in orthognathic patients with different sagittal skeletal discrepancies

ObjectivesThis retrospective study aimed to evaluate the relationship between the Index of Orthognathic Functional Treatment Need (IOFTN) and sagittal skeletal discrepancy (ANB angle) among orthognathic patients. Study DesignRecords of 403 orthognathic patients (229 females/174 males, aged 16-50 years) were reviewed. Malocclusion type (incisor-based), sagittal skeletal relationship (ANB angle), and IOFTN scores were documented. Spearman correlation coefficient (r) and scatter plots were utilized to examine the relationship between functional need (IOFTN scores) and sagittal skeletal discrepancy (ANB angle). Regression analyses were conducted to determine the extent to which variations in IOFTN scores could be attributed to variations in ANB angles. ResultsClass III malocclusion/sagittal skeletal pattern were most prevalent (62.3%). The Spearman correlation coefficient (r) for the entire sample was -0.297 (P<0.001), indicating a weak negative correlation. Linear regression analysis demonstrated a coefficient of determination of 0.069, indicating that approximately 6.9% of the variance in IOFTN data could be accounted for by variations in ANB angles. Upon stratifying data by different malocclusions, coefficients of determination were 0.065, 0.034, and 0.089 for Class I, II, and Class III malocclusions, respectively. ConclusionThe observed linear relationships between sagittal skeletal discrepancy (ANB angle) and IOFTN score were weak and lacked clinical significance.

A retrospective investigation of orthognathic patients and functional needs

Abstract Purpose The present study aimed to explore the malocclusion trends, sagittal skeletal discrepancies, and the index of orthognathic functional treatment need (IOFTN) scores in a sample of Iranian and Turkish orthognathic patients. Methods Four hundred and three orthognathic patients were retrospectively examined (203 Iranian/200 Turkish, 229 females/174 males, aged between 16 and 50 years). The following variables were recorded: malocclusion type (incisor-based), overjet, sagittal skeletal relationship (ANB angle) and IOFTN scores. The sagittal skeletal relationships and malocclusion patterns of the orthognathic patients were statistically examined using Chi-square tests and further explored graphically. The relationship between the IOFTN scores and overjet, as well as the sagittal skeletal discrepancies (ANB angle) was evaluated using box plots and at the 95% confidence interval (CI) in different IOFTN treatment categories (1–3,4,5). The characteristics of a subgroup sample of orthognathic patients and previous studies that identified with low IOFTN scores (1–3) were also explored. Results Class III malocclusions and Class III skeletal patterns were the most prevalent (62.3%), forming 69% and 55.7% of the Turkish and Iranian samples, respectively. Turkish and Iranian samples had more Class III [Mean (SD) ANB angle = -1.24° (4.75°)] and Class II cases [Mean (SD) ANB angle=1.06° (5.63°)], respectively. The mean overjet and reverse overjet for Class II and III malocclusions were 6.96 mm (95% CI, 6.40–7.53 mm) and 3.26 mm (95% CI, 2.87–3.65 mm), respectively. The mean ANB angle for Class II and III malocclusions was 6.64° (95% CI, 6.15°–7.13°) and -3.57° (95% CI, -3.92° to -3.21°), respectively. IOFTN scores of 4 or 5 were identified in 93.8% of the sample. Patients with low IOFTN scores (&lt;4) presented with a nearly normal overjet (mean = 3.19 mm, 95% CI, 2.62-3.76 mm, range = 1–5 mm), accompanied by a wide range of ANB angles [mean (SD)=3.44° (3.86°), range = -4° to 9°] Conclusions The findings at the 95% CI for overjet and the ANB angle can be used as identifiers for patients who would benefit from orthognathic surgery. Analysing patients with a low IOFTN score, particularly with scores of 3.3, 3.10, 2.8, and 1.14, revealed that IOFTN could be used in conjunction with a clinical examination plus diagnostic imaging to facilitate the identification of orthognathic surgery patients.

Effect of surgery-first approach on quality of life and mental health of orthognathic patients: A systematic review and meta-analysis

ObjectivesThis study intends to explore the effects of the surgery-first approach (SFA) on quality of life and mental health of patients who undergo orthognathic surgery compared to the conventional three-stage approach (CTA). DataThe analysis included eight studies with a total of 307 patients, of which one was randomized controlled trial (RCT), one was clinical controlled trial (CCT), and six were non-randomized studies of interventions (NRSIs). SourcesElectronic databases such as Medline, Embase, Scopus, and Web of Science were searched for eligible trials up to April 2023. Study selectionRCTs, CCTs, and NRSIs, which compared the quality of life or mental health of orthognathic patients treated with SFA and CTA, were included in this study. The meta-analysis showed that the standardized mean differences (SMD) of Oral Health Impact Profiles-14 (OHIP-14) scores and the Orthognathic Quality of Life Questionnaire (OQLQ) between SFA and CTA were −1.58 (P = 0.05) and −2.99 (P < 0.00001) at the termination of the first-stage treatment, which altered to −0.94 (P = 0.54) and 0.09 (P = 0.65) after total treatment. Two studies applied the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) and the Beck Depression Inventory (BDI-II) to examine mental health, resulting in a trend similar to the former scales. ConclusionIn contrast to the conventional procedure, orthognathic treatment with SFA can instantly enhance the quality of life at the end of the first-stage treatment but has similar effects after the overall treatment. Moreover, SFA has a positive impact on psychological conditions. Clinical significanceThis study first systematically reviewed the effect of SFA on patients' mental well-being. According to our findings, it is better to select SFA if possible. Otherwise, the patient's psychological condition should be monitored appropriately throughout decompensation for better well-being both physically and mentally.

Systematic Review and Meta-Analysis of the Index of Orthognathic Functional Treatment Need for Detecting Subjects with Great Need for Orthognathic Surgery.

Index of Orthognathic Functional Treatment Need (IOFTN) Identifies patients with greatest need for orthognathic surgery. This systematic review looks into the available evidence on prevalence of patients with great treatment need (IOFTN 4&5) who had orthognathic surgery in previous studies. Literature search of the major electronic databases was carried out for articles published between 2014 and September 2023, looking for "Index of Orthognathic Functional Treatment Need","Orthognathic Surgery","IOFTN", "Epidemiology" and "Dentofacial Deformity". The prevalence of patients identified with IOFTN grades of 4&5 was calculated. A random-effect model was employed and the Forest and Galbraith plots were produced. The pooled prevalence estimate for subjects with IOFTN scores of 4&5 was calculated. The heterogeneity among studies was assessed with the I2 statistics. In total, 14 retrospective studies conducted between 2015 and 2019 in 7 countries (UK, New Zealand, Iran, Pakistan, Turkey, Malaysia, Japan) were included, reporting on 1339 orthognathic patients. The sample sizes ranged from 30 to 200. Only 7 studies reported on the subcategories of the IOFTN for grades 1, 2&3. The prevalence of orthognathic patients with IOFTN scores of 4 & 5 ranged from 79% to 100%. The heterogeneity I2 statistics was high (76%, random effects model) for 14 studies, but after removing 3 outlier studies reduced to zero. The pooled prevalence estimate for subjects with IOFTN scores of 4&5 was 93% (95% CI, 0.91-0.94%). According to this meta-analysis, IOFTN successfully identified 93% of patients who underwent orthognathic surgery with a great need for treatment (Grade 4 & 5). To enhance the identification of patients with well-compensated malocclusions, previous orthodontic treatment, or extreme occlusal deviations (e.g., proclination or retroclination of incisors), it would be advantageous to employ additional means alongside IOFTN for assessing orthognathic need in this group.

Male and Female Discrepancies in Anxiety, Depressive Symptoms, and Coping Strategies among Orthognathic Patients: A Cross-Sectional Analysis.

With an increasing understanding of the differences between men and women's psychological experiences, this study aimed to probe the sex-based differences in anxiety, depressive symptoms, and coping strategies among orthognathic patients. The study hypothesis was that female patients would show higher levels of anxiety and depressive symptoms than males, and that coping mechanisms would differ between male and female sexes. A cross-sectional design was adopted, examining orthognathic patients from the Department of Oral and Maxillo-Facial Surgery at the Emergency Clinical Municipal Hospital in Timisoara, Romania, from 2020 to 2023. Eligible participants (18+ years with no prior orthognathic treatment) completed a comprehensive online questionnaire 6 weeks before scheduled surgery. This was composed of validated self-report instruments comprising the SF-36, GAD-7, and the PHQ-9, and the COPE-60, along with additional sociodemographic data. Of the 127 orthognathic patients analyzed (68 men and 59 women, aged 18 to 65 years, mean age 32), men rated their physical health status slightly better on the SF-36 scale. However, the most notable difference was in mental health, with females scoring higher on both the PHQ-9 (indicative of depression) and the GAD-7 (indicative of anxiety) scales. Specifically, female participants exhibited average PHQ-9 scores 1.8 points higher and GAD-7 scores 1.5 points higher than their male counterparts. Coping mechanisms also varied: 42% of male patients primarily employed "Disengagement" strategies, while 58% of females predominantly used "Engagement" and "Emotion Focused" strategies. Emotion-focused coping was associated with a 1.6-fold increased risk of depressive symptoms. Sex differences play a crucial role in the psychological experiences of orthognathic patients, evident in anxiety and depression levels, perceived health status, and coping strategies. This underlines the importance of sex-tailored psychological support in the preoperative phase for orthognathic surgery patients.

Quantifying bone healing after mandibular displacement in orthognathic surgery

Impaired bony healing following bilateral sagittal split osteotomy (BSSO) is a major unmet medical need for affected patients, and rare occurrences can hinder the identification of underlying risk factors. We hypothesised that osseous union following BSSO can be quantified using volumetric analysis, and we aimed to identify the risk factors for impaired bone healing. The percentage change in bony volume was measured in orthognathic patients following BSSO using two consecutive postoperative cone-beam computed tomography scans. Patients’ characteristics and treatment parameters were documented, and correlation and regression analyses of these variables performed. Thirty-six patients (23 men and 13 women) with a mean (SD) age of 33.28 (11.86) years were included. The gap site (lingual versus buccal) (p < 0.01) had a significant impact on the change in volume. Age (p = 0.06) showed a trend towards significance. Initial width of the osteotomy gap, sex, and indication for surgery did not influence osseous healing. Increased age at surgery and the side of the buccal osteotomy are independent risk factors for impaired osseous healing following BSSO.

Multidisciplinary orthodontic-orthognathic management of severe skeletal Class III malocclusion and anterior open bite

This case report presents the multidisciplinary management of a patient with severe skeletal Class III malocclusion, anterior open bite, dentigerous cyst, and multiple restorations. The patient underwent orthodonticorthognathic treatment, autotransplantation, cyst removal, and esthetic rehabilitation with porcelain veneers. The presurgical orthodontic decompensation of the proclined upper incisors involved mini-screw-assisted entire upper arch distalization. The bimaxillary osteotomy included advancing the maxilla, mandibular setback, rotating the maxillomandibular complex clockwise, and moving the chin posteriorly. The role of multidisciplinary treatment is very important in orthognathic patients with compromised dentition. Autotransplantation could help patients avoid the need for prosthetic implants. Entire arch distalization could be a possible alternative to premolar extraction for presurgical orthodontic decompensation in cases of proclined incisors.

Surgical accuracy of CAD/CAM splints using virtual surgical planning in orthognathic surgery: policy implications for healthcare in Australia.

This study examines post-surgical outcomes of maxillary position using virtual surgical planning (VSP) with computer designed and manufactured surgical splints, without the use of costly patient specific implants (PSI), in the treatment of routine nonsyndromic orthognathic patients. The cost of these personalized medical devices and their impact in the setting of cranio-maxillofacial surgery is currently under review by The Department of Health and Aged Care in Australia. This is a single-centre retrospective analysis of 49 patients who underwent bimaxillary orthognathic surgery by a single surgeon at Epworth Richmond Hospital (Victoria, Australia) over a period spanning 2016 to 2020. Patients were included in the study provided their surgery was facilitated using VSP with manufacture of computer designed occlusal splints. Use of computer designed and manufactured splints were highly reliable in reproducing the virtual surgical plan, when using palatal plane, upper incisor angulation, and anterior upper facial height. Use of computer designed and manufactured splints provide a method of leveraging the accuracy of VSP methods, without the additional costs associated with PSI. These findings may assist in appropriate resource allocation and case stratification in patients undergoing orthognathic surgery.

Improvement in facial aesthetics of orthognathic patients after surgery-first approach

Facial appearance significantly affects psychosocial wellbeing, and an improvement in facial aesthetics is considered an essential outcome of orthognathic treatment. The surgery-first approach (SFA) has emerged as a promising alternative to the conventional orthodontics-first approach (OFA) due to its potential advantages in reducing treatment duration and cost, delivering early aesthetic improvement, and increasing patient satisfaction. However, its impact on final facial aesthetics and how it compares with the OFA has, to our knowledge, not yet been investigated. This retrospective study aimed to compare the improvement in facial aesthetics after orthognathic surgery in an SFA and an OFA group. Preoperative and postoperative 3-dimensional stereophotogrammetry facial images of 40 patients were evaluated by five professional assessors using the Global Aesthetic Improvement Scale (GAIS). Similar aesthetic improvement outcomes were found in both the SFA and OFA groups. The GAIS score significantly correlated with the following facial variables: upper lip projection, chin prominence, facial proportions, paranasal hollowing, lip competence, mandibular projection, and facial profile. No significant correlation was found between a change in aesthetic score and the surgical variables. There was a positive association between overall GAIS score and the gender and experience level of the individual assessors. This study suggests that aesthetic facial improvement achieved with the SFA is satisfactory and comparable to that of the OFA.

Translation, Transcultural Adaptation, and Validation of the Hebrew Language Version of the Orthognathic Quality of Life Questionnaire for the Assessment of Quality of Life in Orthognathic Patients.

Dentofacial deformities impose a negative impact on quality of life (QOL). Orthognathic surgery is the main pillar of treatment for these conditions and has proven its impact on the improvement of the functional and psychosocial aspects of QOL. The Orthognathic Quality of Life Questionnaire (OQLQ), developed by Cunningham and colleagues, is a well-established instrument for assessing QOL in patients with dentofacial deformities. The aim of this study was to perform a translation, transcultural adaptation, and validation of a Hebrew version of the OQLQ. Transcultural adaptation was done following guidelines proposed by Beaton and colleagues resulting in a pilot study conducted on 20 patients undergoing orthognathic surgery. Internal consistency, reliability, and sensitivity were evaluated by means of Cronbach alpha, intraclass correlation coefficient (test-retest), and Wilcoxon test, respectively. Validity was assessed by comparing the OQLQ with the Hebrew version of the Oral Health Impact Scale-14 (Oral Health Impact Profile Scale-14) using the Spearman correlation test. Internal consistency showed a good correlation between domains and excellent test-retest reliability. Sensitivity to change was statistically significant in all but 3 questions. The Hebrew version of the OQLQ exhibited a strong correlation with Oral Health Impact Profile Scale-14 in total score and moderate to high correlations among domains. The Hebrew version of the OQLQ is a valid and reliable and specific instrument to measure QOL for Hebrew-speaking patients undergoing orthognathic surgery.

A Cross-Sectional Study of Factors Influencing Pre-Operative Anxiety in Orthognathic Patients.

Orthognathic treatment is an important treatment modality to manage severe dentofacial discrepancies. Patients awaiting orthognathic surgery often experience increased anxiety, which may adversely affect post-operative recovery and treatment satisfaction. This study investigated the effects of a number of factors on pre-operative anxiety in orthognathic patients. Seventy patients prospectively recruited from three orthognathic centres in the UK completed a pre-operative questionnaire that included validated scales for measuring anxiety, social support, resilience, and coping styles. Sociodemographic data and satisfaction with the information provided by the clinical team were also elicited from the questionnaire. Univariable analysis showed that social support from a significant other (p = 0.026), resilience (p < 0.001), and satisfaction with the information provided by the clinical team (p = 0.002) were significantly associated with reduced anxiety, whilst avoidance coping (p < 0.001) and coping through seeking social support (p = 0.006) were significantly related to increased anxiety. With the exception of coping by seeking social support, these relationships retained significance in a multivariable regression analysis. Neither gender nor ethnicity moderated the effects of social support on pre-operative anxiety. These findings suggest potential avenues for clinicians to address with future interventions to reduce pre-operative anxiety. Further qualitative research may provide greater clarity on the relationship between these variables and anxiety.

Prickle planar cell polarity protein 1 involved in the pathogenesis of skeletal class Ⅲ malocclusion

Objective: To explore the mechanisms of prickle planar cell polarity protein 1 (PRICKLE1) involved in the occurrence of skeletal Class Ⅲ malocclusion. Methods: After extracting the genomic DNA of all family members of the skeletal Class Ⅲ malocclusion pedigree with maxillary hypoplasia collected in the Department of Orthodontics at the Affiliated Stomatological Hospital of Nanjing Medical University in October 2021, whole exome sequencing and Sanger sequencing were performed to screen pathogenic genes/mutation sites and validate the mutations. Jaw tissue was collected during the operation of orthognathic patients who were treated in the Department of Oral and Maxillofacial Surgery at the same hospital from October 2021 to December 2022. Following the extraction of human jaw bone marrow mesenchymal stem cells and transfection with overexpressing lentivirus (lentiviruses overexpressing the gene of interest served as the wild group, lentiviruses overexpressing mutation site served as the mutant group) and knockdown lentivirus (divided into knockdown group 1 and 2, with transfection interference negative lentiviruses as the control group). Various assays including real-time fluorescence quantitative PCR (RT-qPCR), Western blotting, proliferation and Transwell assays, alkaline phosphatase staining and alizarin red staining were performed. Construction of zebrafish animal model, antisense morpholino oligonucleotide (MO) were injected to knock down the expression of prickle1a and prickle1b in zebrafish (co-knocking group), and the control group was injected with standardized MO as a reference. Transcriptome sequencing, enrichment analysis and co-expression analysis were performed on the zebrafish craniofacial tissues of the two groups. Results: Two patients of this family carried this mutation PRICKLE1 c.113C>T. The transfection experiments showed that compared with the wild group (relative expression of PRICKLE1 was 21.97±0.60), the relative expression of mutant group (5.05±0.05) was significantly reduced (P<0.05), and cell proliferation and migration ability significantly enhanced (P<0.05), and osteogenic differentiation ability was significantly reduced (P<0.05). Compared with the control group, the proliferation and migration ability of cells in the two knockdown groups were significantly enhanced (P<0.05), and the osteogenic differentiation ability was significantly reduced (P<0.05). Zebrafish model experiments showed the width of the ethmoid plate was significantly reduced in the co-knocking group (282.50±61.77, t=5.29, P<0.001) compared with the control group (338.80±24.92). Transcriptome data and enrichment analysis showed that the differentially expressed genes were significantly enriched in the mitogen-activated protein kinase (MAPK) signaling pathway after the simultaneous knockdown of prickle1a and prickle1b in zebrafish. Conclusions: PRICKLE1 c.113C>T mutation might suppress the osteoblastic differentiation ability of jaw bone marrow mesenchymal stem cells by downregulating the MAPK signaling pathway, thereby involving the development of skeletal Class Ⅲ malocclusion.

Demographic of orthognatic cases seen in Kulliyyah of Dentistry IIUM

Orthognathic treatment is a combination of orthodontics and surgery, aimed to restore functional occlusion and the facial aesthetics. KOD orthognathic team has been established since 2018. There was no published demographic profile of the orthognathic patients referred. This study aimed to enumerate the demographic data and correlations for the orthognathic cases seen in KOD, IIUM from 2018 until December 2020. A total of 28 patients were referred for consultation. One patient was excluded as no referral letter was attached. Data were obtained from patients’ case notes, photos and study models. Data collected were then categorized into patients’ demographic profiles, clinical features, patients’ psychological status and treatment. The demographic pattern and correlations were analysed using SPSS version 25.0. Out of 27 patients, most patients were females (66.7%), Malay (55.6%) and within the age group of 21 to 30 years old (44.4%) and originated from Pahang (88%). Majority of patients presented with Class III skeletal base discrepancy (66.7%), facial asymmetry (76.0%), increased vertical dimension (51.9%), shifted chin point (83.3%), Class III incisal relationship (70.4%), reversed overjet (70.4%), reduced overbite (56.0%) and crossbite (77.7%). Significant relationships were found between skeletal base discrepancy with incisal relationship, overjet, crossbite, canine relationships and right molar relationship. 57.1% agreed to orthognathic surgery, 32.1% opted for orthodontic treatment alone whilst 10.7% refused any treatment. It is hoped that this baseline demographic data may aid in the management and resource planning for this team in the future.

Differences in the stability of the lesser and greater maxillary segments after cleft orthognathic surgery: A retrospective study using 3D analysis

The aim of this study was to determine whether significant differences in postoperative stability exist between the lesser and the greater maxillary segments after cleft orthognathic surgery in patients with and without residual alveolar cleft.A retrospective study of orthognathic patients with unilateral cleft was conducted. The patients were divided into two groups according to maxillary status before surgery, with group 1 comprising single-piece maxilla and group 2 comprising two-piece maxilla. Four maxillary points were used for intra- and intergroup comparisons of movements and relapses between the two maxillary segments.In total, 24 patients were included. The intragroup comparison showed significant differences in vertical relapses between lesser and greater segments in both group 1 (anterior, p = 0.004 and posterior, p = 0.01) and group 2 (posterior, p = 0.013). With regard to intergroup comparison, the lesser segments in the two groups differed in transverse movements (anterior, p = 0.048) and relapses (posterior; p = 0.04), while the greater segments differed in transverse movements (anterior, p = 0.014 and posterior, p = 0.019), with significant differences in relapses anteriorly (vertical, p = 0.031 and sagittal, p = 0.036) and posteriorly (transverse, p = 0.022).Maxillary changes following cleft orthognathic surgery showed significant differences between the lesser and the greater segments. These findings imply that 3D images should be used to assess each maxillary segment separately with regard to planning and outcome evaluation.

Characteristics of orthognathic multidisciplinary team clinics in England. Part 1: A questionnaire survey.

Orthognathic clinics across England are currently run in a multidisciplinary team (MDT) format. It is, however, likely that there is a large variation in the style of these clinics and care pathways for orthognathic patients across the country. This was a cross-sectional, online questionnaire with a primary aim to obtain information on the way orthognathic care is currently delivered throughout England. The secondary objectives were to determine the compliance to the minimum dataset for record collection. The questionnaire, disseminated to orthodontic consultants, detailed 27 items split into waiting lists for new patients, mechanics of the clinic, support for patients and record collection. A total of 36 participants responded (one was excluded) to give a total of 35 questionnaire responses. Descriptive statistics were used to analyse the data. Of the participants, 34% followed up their patients as per the commissioning guidelines at 1, 2 and 5 years after treatment. Of the participants, 20% said patients' mental health would be screened before adding them to a waiting list, with 26% of participants stating screening was not undertaken for all patients. Of the participants, 11% had available access to psychological support during the MDT meeting and 20% recorded the minimum dataset at the follow-up intervals. There are inconsistencies in the orthognathic MDT design across England. Acceptance criteria, support services available and records collected for patients showed substantial variation, highlighting the limited guidance offered by the commissioning guidelines and the potential need to revise the minimum dataset.

Is Beauty a Matter of Volume Distribution? Proposal of a New Aesthetic Three-Dimensional Guide in Orthognathic Surgery.

Orthognathic surgery is a multidisciplinary surgery in which the aesthetic results have become increasingly important, and consequently, also the predictability of the surgical outcomes. In this paper, we analyzed the volumetric distribution of the lower two-thirds of the face, in patients operated by orthognathic surgery and selected for their attractiveness. Our goal was to analyze the aesthetic volumetric distribution for gender and to propose our operating philosophy, that a normative distribution of facial volumes could be used like a new 3D aesthetic guide in orthognathic planning. A group of 46 orthognathic patients (26 females, 20 males) with the best postoperative aesthetic score was selected by a jury of plastic surgeons, orthodontists, and journalists. The mean soft tissue volumes of the malar, maxillary, mandibular, and chin regions were analyzed. Overall, we measured a mean female facial volume distribution of 38.7%, 29%, 27.6%, and 4.7%, respectively, in the malar, maxillary, mandibular, and chin regions, while in males, it was 37%, 26%, 30%, and 6%, respectively. In this paper, the expansion of facial volumes in orthognathic surgery is proposed as a key point for facial harmonization. Beauty could be scientifically interpreted as a balanced distribution of facial volumes, and the virtual study of this distribution can become an important part of the preoperative analysis, such as a "volumetric" 3D cephalometry, where the surgeon could use average values of aesthetic volumetric distribution as preoperative surgical references.

Cumulative exposure and lifetime cancer risk from diagnostic radiation in patients undergoing orthognathic surgery: a cross-sectional analysis

Radiation doses in dentomaxillofacial imaging are typically very low. However, diagnostic and follow-up protocols in orthognathic surgery result in a patient-specific risk in effective dose. Estimating the cancer risks from these exposures remains abstract for many maxillofacial surgeons. In this study, 40 orthognathic patients were randomly sampled and their cumulative effective dose (ED) calculated. The lifetime attributable risk of cancer (LAR) was calculated based on the standard radiological protocol for orthognathic surgery follow-up using methods described in the BEIR VII report and RadRAT. The mean cumulative ED of the 40 sampled patients at the end of their 2-year follow-up period was 1.91 ± 0.58 mSv. The LAR at the end of follow-up was 17.65 (90% confidence interval 6.46–32.90) per 100,000 person-years for male orthognathic patients and 13.93 (90% confidence interval 6.27–25.24) per 100,000 person-years for female orthognathic patients. This represents 0.70% and 0.68%, respectively, of the baseline cancer risk for oral, thyroid, and brain cancer combined. Although theoretical, these results provide a framework for interpreting radiation doses and cancer risks in patients undergoing orthognathic surgery. Considering the increased radiation sensitivity in children and adolescents, indication-oriented and patient-specific imaging protocols should be advised.