This study investigates the corrosion response of Al-Li alloy following deformation along three strain paths, viz. uniaxial, plane strain, and equi-biaxial. The electrochemical studies have revealed that the dissolution behaviour of the as-received and deformed specimens is significantly influenced by grain orientation and grain boundary character distribution. The higher fraction of 〈001〉 // ND grains minimises the dissolution rate by forming a stable film over the specimen. The densely populated sub-grain boundaries, distributed uniformly throughout the microstructure, improve the charge transfer resistance and compensate for the deterioration in corrosion behaviour induced by the presence of higher fraction of 〈011〉 // ND grains. Further, a microstructure consisting of both 〈001〉 // ND and 〈011〉 // ND oriented grains induces micro-galvanic corrosion and forms a highly non-uniform film, degrading the overall corrosion response.