View Of Organization Research Articles

Engaging firms and populations in ecosystem web: deploying a multi-paradigmatic construct to resolve pluralism in organizational theory

Strategic management theorists, organizational ecologists, organizational theorists, and ecosystem theorists deploy different perspectives to theorize, model, and analyze organizational forms. Organizational constructs, independent of the unitary or aggregate level, can be seen along the duality of social determinism and free will. The four configurations of organizational forms, namely, system structure, strategic choice, natural selection, and collective action view, adapted from organizational theory literature, are modeled from the business ecosystem perspective. Disruptive forces in the environment warrant organizational forms that can withstand the disruption. Deploying business ecosystems as an integrative organizational theory construct can provide meaningful insights in the form of a novel architecture that can consolidate multi-paradigmatic perspectives appropriate for all organizational forms. This study leverages the power of analogy, transverses the conceptual underpinning of the term business ecosystem, reveals the intricacies of firm and population behavior, and explains relationships across various organizational forms within the ecosystem construct. Toward the end, the authors propose a business ecosystem as a multi-paradigmatic, meta-theoretical construct to map and navigate diverse organizational forms, thereby guiding the thoughts and actions of thinkers and practitioners in organizational theory.

Willingness to Pay for Community-based Health Insurance: A Systematic Review and Analysis of Factors Influencing Participation and Implications for Healthcare Financing

Willingness to pay (WTP) for community-based health insurance (CBHI) is a crucial factor in understanding individuals’ attitudes and behaviours towards participating in insurance schemes. This article aims to examine the concept of WTP for CBHI and its implications for healthcare financing and accessibility. The research gives an organized and retrospective view of the antecedents, decisions and outcomes (ADO) of CBHI using a systematic review. The article also provides an overview of the theories, contexts and methods (TCM) employed to gain this understanding. The analysis concludes by identifying existing knowledge gaps and suggesting relevant ideas for future WTP and CBHI research. This article contributes to the existing body of knowledge on WTP for CBHI and provides insights for policymakers and researchers seeking to enhance the sustainability and effectiveness of CBHI programmes.

Spatiotemporal transcriptomic map of glial cell response in a mouse model of acute brain ischemia

The role of nonneuronal cells in the resolution of cerebral ischemia remains to be fully understood. To decode key molecular and cellular processes that occur after ischemia, we performed spatial and single-cell transcriptomic profiling of the male mouse brain during the first week of injury. Cortical gene expression was severely disrupted, defined by inflammation and cell death in the lesion core, and glial scar formation orchestrated by multiple cell types on the periphery. The glial scar was identified as a zone with intense cell-cell communication, with prominent ApoE-Trem2 signaling pathway modulating microglial activation. For each of the three major glial populations, an inflammatory-responsive state, resembling the reactive states observed in neurodegenerative contexts, was observed. The recovered spectrum of ischemia-induced oligodendrocyte states supports the emerging hypothesis that oligodendrocytes actively respond to and modulate the neuroinflammatory stimulus. The findings are further supported by analysis of other spatial transcriptomic datasets from different mouse models of ischemic brain injury. Collectively, we present a landmark transcriptomic dataset accompanied by interactive visualization that provides a comprehensive view of spatiotemporal organization of processes in the postischemic mouse brain.

A IMPORTÂNCIA DO PLANO DE NEGÓCIO PARA O MICROEMPREENDEDOR INDIVIDUAL NA ABERTURA DE LOJA DE COSMÉTICOS

Objective: Emphasize the importance of the business plan for Individual Microentrepreneurs when opening a cosmetics store. Methods: This is bibliographical research, where data was collected by searching for articles in the Acervo Mais and Google Scholar databases, applying the filter of works in Portuguese, published in the last 5 years. For analysis of the results and discussion, five complete works were selected. Results: When you prepare a business plan you have a clearer and more organized view of the enterprise, making it easier to study your objectives and measure your results and put your ideas into practice. It was possible to identify that the perfumery and cosmetics sector is a great opportunity for Individual Microentrepreneurs and the business becomes more attractive and profitable with the sale of perfumes, makeup items and hair products. Final Considerations: It is viable to open a cosmetics store, due to the great customer demand and wide variety of products, even with competition, but it is essential to develop a business plan for this venture.

An integrated view of the structure and function of the human 4D nucleome.

The dynamic three-dimensional (3D) organization of the human genome (the "4D Nucleome") is closely linked to genome function. Here, we integrate a wide variety of genomic data generated by the 4D Nucleome Project to provide a detailed view of human 3D genome organization in widely used embryonic stem cells (H1-hESCs) and immortalized fibroblasts (HFFc6). We provide extensive benchmarking of 3D genome mapping assays and integrate these diverse datasets to annotate spatial genomic features across scales. The data reveal a rich complexity of chromatin domains and their sub-nuclear positions, and over one hundred thousand structural loops and promoter-enhancer interactions. We developed 3D models of population-based and individual cell-to-cell variation in genome structure, establishing connections between chromosome folding, nuclear organization, chromatin looping, gene transcription, and DNA replication. We demonstrate the use of computational methods to predict genome folding from DNA sequence, uncovering potential effects of genetic variants on genome structure and function. Together, this comprehensive analysis contributes insights into human genome organization and enhances our understanding of connections between the regulation of genome function and 3D genome organization in general.

The Effect of Ambidextrous CIO Leadership on Strategic Alignment Through Knowledge Integration Mechanisms

Information technology (IT)-business alignment continues to be a challenge for businesses. A potential reason may be the absence of relevant IT leadership capable of engaging IT and business units in a way that leads to alignment. Based on the knowledge integration view of organizations and the strategic leadership literature, we propose a model linking chief information officer (CIO) leadership style to IT-business alignment. We examine how ambidextrous CIO leadership behavior influences IT-business alignment through knowledge integration mechanisms, namely mechanisms that develop shared domain knowledge between IT and business specialists and mechanisms for collaborative integration of specialized IT and business knowledge. Analysis of cross-industry data collected from CIOs, top management team members, and IT specialists indicates that CIOs who can display both transformational and transactional leadership promote these mediating mechanisms. Moreover, the results show that these mechanisms have a substitutive effect, in that the effect of one mechanism diminishes when the other exists at a high level.

Construction 4.0 implementation for performance improvement: an innovation management perspective

Purpose The emergence of Construction 4.0 technologies provides an impetus for radical change and rejuvenates the interest of stakeholders in addressing long-standing performance issues in the construction sector. However, construction firms struggle to implement Construction 4.0 technologies for performance measurement and improvement. Therefore, the purpose of this research is to develop a conceptual model of innovation management for implementing Construction 4.0 that guides and facilitates the strategic transformation of construction firms. Design/methodology/approach A conceptual model of innovation management is presented, and the findings are synthesised based on a literature review, 20 semi-structured interviews, two focus group discussions, three workshops, expert consultation and observations on three digitally-enabled projects. Data were inductively analysed using thematic analysis. Findings The analysis of empirical data revealed: (i) Four scenarios that could lead the industry to different futures, based on the extent of research and development, and the extent of integration/collaboration; (ii) Construction 4.0 capability stages for a sustained implementation route; (iii) Possible business model configurations derived from servitisation strategies; and (iv) Skills management challenges for organisations. Research limitations/implications First, the empirical data was only collected in the UK with its unique industry context, which may limit the applicability of the results. Second, most of the research data comes from the private sector, without the views of public sector organisations. Third, the model needs to be further validated with specific data-driven use cases to address productivity and sustainability issues. Practical implications Successful Construction 4.0 transformation requires a concerted effort of stakeholders, including those in the supply chain, technology companies, innovation networks and government. Although a stakeholder’s action would depend on others’ actions, each stakeholder should undertake action that can influence the factors within their control (such as the extent of collaboration and investment) and the outcomes. Originality/value The conceptual model brings together and establishes the relationships between the scenarios, Construction 4.0 capability stages, business models and skills management. It provides the first step that guides the fuzzy front-end of Construction 4.0 implementation, underpins the transformation to the desired future and builds long-term innovation capabilities.

Transcription dynamics and genome organization in the mammalian nucleus: Recent advances.

Single-molecule tracking (SMT) has emerged as the dominant technology to investigate the dynamics of chromatin-transcription factor (TF) interactions. How long a TF needs to bind to a regulatory site to elicit a transcriptional response is a fundamentally important question. However, highly divergent estimates of TF binding have been presented in the literature, stemming from differences in photobleaching correction and data analysis. TF movement is often interpreted as specific or non-specific association with chromatin, yet the dynamic nature of the chromatin polymer is often overlooked. In this perspective, we highlight how recent SMT studies have reshaped our understanding of TF dynamics, chromatin mobility, and genome organization in the mammalian nucleus, focusing on the technical details and biological implications of these approaches. In a remarkable convergence of fixed and live-cell imaging, we show how super-resolution and SMT studies of chromatin have dovetailed to provide a convincing nanoscale view of genome organization.

Impact of Management Practices on Talent Retention Using Talent Analytics Metrics

Human resources are an evitable resource for achieving organizational goals. Human resources are no longer merely a factor of production but now play a crucial role in successful organizations. Every employee represents a bouquet of Competencies or talent. Many organizations view Human Resource Management as Talent Management. This study examines the relationship between talent analytics and employee retention. Talent analytics encompasses the processes, strategies, and technologies used to manage HR operations in an organization. Talent Analytics encompasses data-driven decision-making and analysis. Attrition among workers is the opposite of employee retention. Talent Analytics may favourably impact several aspects of Talent Management, including recruitment, training, retention, career promotion, and redeployment. solutions. Many organisations can use historical data to forecast future outcomes. Employees who frequently visit job sites are more likely to leave the organisation for better opportunities. An employee with a large number of unresolved professional grievances may depart the organisation. Over 250 employees in the industrial sector provided feedback on the use of Talent Analytics. All of these responders are from Chennai. Data research revealed that most respondents believe Talent Analytics improves employee retention. The researcher investigated the relationship between the availability of a Talent Analytics System in a respondent's organisation and their intention to stay.

Environmental factors affecting the mortality of population in Odesa Region

The presented research covers a significant part of the period of the COVID-19 pandemic and studies the role of environmental factors in formation of population mortality from main causes. The main causes of mortality among the population of Odesa Region during the studied period include diseases of circulatory system, COVID-19, neoplasms, external causes, diseases of digestive organs and diseases of respiratory organs. The aforesaid causes constitute 94-95% of all causes of mortality in Odesa Region. However, out of these six classes of diseases, only diseases of circulatory system, COVID-19 and diseases of respiratory organs and some of their nosological forms have simultaneous peaks in mortality, during which mortality of the Odesa Region population from all causes almost doubles. Over time, there is a certain redistribution of frequency of the causes of mortality among the six main causing diseases of the population`s mortality in the region. But this does not explain occurrence of simultaneous peaks in mortality from diseases of circulatory system, COVID-19, and diseases of respiratory organs. Formation of simultaneous peaks in mortality from non-infectious and infectious diseases cannot be explained by the influence of social or anthropogenic factors. This indicates the need to address a number of environmental factors of natural origin – meteorological, biometeorological and heliocosmic. The study shows the possibility of an existing linear statistical connection between these environmental factors and the mortality of the Odesa Region population from such classes of diseases as diseases of circulatory system, COVID-19 and diseases of respiratory organs, as well as the relevant nosological forms. The results of the correlation analysis between mortality rates from major diseases and the environmental factors studied showed weak correlations between them. It is fully consistent with the World Health Organization's view of the role of environmental conditions in shaping public health.

Research on Identification of the Capacity Influencing Factors of Youth Sports Clubs in China

Since the 1970s, nonprofit organizations have identified organizational capacity as the key to improving organizational effectiveness. Youth sports clubs have long been trapped in a predicament that makes it difficult for them to keep non-profit nature, operate independently and maintain high performance for a long time. This study investigates which influencing factors can act on the capacity of youth sports clubs to ensure their non-profit nature whilst achieving healthy and sustainable development. The organizational theory systems view emphasizes the relationship between open internal structures and the role of external environmental factors, therefore the capacity influencing factors of youth sports clubs can be comprehensively considered to achieve this by considering both the internal and external influencing components of organizational capacity. The focus of this study was obtained by searching 11 relevant policy documents, 21 papers, and in-depth interviews with 26 experts including youth sports club managers, coaches, and venue management personnel and scholars studying in the field of youth sports research or practice. The study revealed the internal and external influences on youth sports club capabilities, including strategic leadership, service innovation, resource acquisition, network relationships, policy, social media, and environmental uncertainty; and constructed a relationship between internal and external influences on youth sports club capabilities and organizational effectiveness. In addition, we found that Social media had the highest weight, policy had the lowest weight, and the rest of the influences did not differ significantly by the method of the weight calculation. We recommend that youth sports clubs increase the application of social media, stimulate employees' service and innovation ability, and cultivate the strategic leadership ability of leaders.

Mapping the imaginary of Information Communication Technologies (ICTs) in education: the case of Botswana

ABSTRACT This article investigates policy-as-discourse and policy-as-technology with specific focus on how the deployment of Information and Communication Technology (ICT) in education is positioned as a redemptive force in the case of Botswana. Therborn's theory of inequalities was adopted to catalogue ways in which supranational organisations and the national government of Botswana consider the potential of ICT and/ICT in education to address (in)equalities in Botswana. A deductive Directed Qualitative Content Analysis (DQICA) was adopted focusing on how the national government and supranational organisations view and present ICT in education in Botswana with regards to being an equaliser. The analysis of the evidence points to ICT in education being seen and operationalised to ameliorate existing inequalities in education and broader society, without, necessarily, questioning broader socioeconomic structural arrangements and factors sustaining inequalities.

Организационно-правовые модели управления крупными городами: городской округ с делением на административные районы, не являющиеся муниципальными образованиями, и городской округ с внутригородским делением

This work is devoted to the consideration and analysis of management models of large urban districts from the point of view of territorial organization. The constant increase in the territory and population in large municipalities with the status of urban districts requires certain changes in the mechanism of exercising power. Currently, there are two models in the Russian Federation that define the territorial organization of government in urban districts. At the first, a unified system of local self-government bodies is maintained, and at the same time, administrative districts are created where territorial divisions of citywide bodies operate to improve the quality of management of individual parts of the city. The second involves the creation of a two-level structure of local self-government bodies, when inner-city districts are formed as independent municipalities with their own competence. The study found that when choosing any of these organizational and legal models, there are a number of features and nuances that affect the quality and nature of the exercise of power, which should be taken into account when implementing and adapting them.

Systematic characterization of immunoglobulin loci and deep sequencing of the expressed repertoire in the Atlantic cod (Gadus morhua)

BackgroundThe Atlantic cod is a prolific species in the Atlantic, despite its inconsistent specific antibody response. It presents a peculiar case within vertebrate immunology due to its distinct immune system, characterized by the absence of MHCII antigen presentation pathway, required for T cell-dependent antibody responses. Thorough characterisation of immunoglobulin loci and analysis of the antibody repertoire is necessary to further our understanding of the Atlantic cod’s immune response on a molecular level.ResultsA comprehensive search of the cod genome (gadmor3.0) identified the complete set of IgH genes organized into three sequential translocons on chromosome 2, while IgL genes were located on chromosomes 2 and 5. The Atlantic cod displayed a moderate germline V gene diversity, comprising four V gene families for both IgH and IgL, each with distinct chromosomal locations and organizational structures. 5’RACE sequencing revealed a diverse range of heavy chain CDR3 sequences and relatively limited CDR3 diversity in light chains. The analysis highlighted a differential impact of V-gene germline CDR3 length on receptor CDR3 length between heavy and light chains, underlining different recombination processes.ConclusionsThis study reveals that the Atlantic cod, despite its inconsistent antibody response, maintains a level of immunoglobulin diversity comparable to other fish species. The findings suggest that the extensive recent duplications of kappa light chain genes do not result in increased repertoire diversity. This research provides a comprehensive view of the Atlantic cod's immunoglobulin gene organization and repertoire, necessary for future studies of antibody responses at the molecular level.

Perkawinan dengan Ahli Kitab Perspektif Ulama Indonesia: Sebuah Kajian Literatur

In the context of faith, People of the Book is a special term in the Koran and the study of Islamic law which differentiates it from other terms such as Muslim, believer, polytheist and unbeliever. Because it is a special term, interactions between Muslims, such as marriage with People of the Book, have different sharia legal implications from polytheists and infidels. However, the views of the scholars differ regarding who and the legal implications that accompany the People of the Book. Using qualitative methods and literature review, this research discusses the views of ulama or religious organizations regarding the People of the Book in discussions in academic journals for the 2019-2024 period. The search results regarding the views of ulama or religious organizations regarding the People of the Book are not single. There are groups that define it narrowly so that it has legal implications that marriage with People of the Book (Jews and Christians) becomes haram. Even if the man is Muslim. There are also those who allow it. Then there are groups that expand the definition of People of the Book not only limited to Christians/Christians but other religions such as Magi, Zoroastrians, Confucians and others so that it has implications for the permissibility of marriage with People of the Book.

Problems of civil protection of residential buildings in the cities of Ukraine in the context of sustainable development

The problems of civil defense (CD) of the population are relevant in the formation of new residential buildings and the reconstruction of existing residential areas from the point of view of urban planning organization of residential areas in the cities of Ukraine. The need to determine the compliance of the regulatory and legal provision of the civil defense process and the principles and techniques of the formation of residential buildings with protective structures in the conditions of military operations is one of the primary tasks. The largest number of defensive structures is being built in cities close to the existing front line. New requirements for the construction of protective structures form a new look of modern Ukrainian cities based on the latest research on threats of a military and terrorist nature. The existing methods of ensuring CD expose the lack of comprehensiveness in solving this problem. The need to provide residential buildings with protective structures exposes the need for rethinking their typology, implementing the latest scientific and technical achievements. The analysis of the existing situation of protective structures (shelters and storages) and the trend of building new ones indicates the problems faced by the spheres of architecture, urban planning and civil defense of Ukraine. Fragmentation and episodic nature in the provision of civil protection can be understood as a forced response to current challenges, however, in the future, this all-encompassing field must also be large-scale and take into account modern trends - sustainable development and the creation of a truly safe space for people and the surrounding environment.

STPDA: Leveraging spatial-temporal patterns for downstream analysis in spatial transcriptomic data

Spatial transcriptomics, a groundbreaking field in cellular biology, faces the challenge of effectively deciphering complex spatial-temporal gene expression patterns. Traditional data analysis methods often fail to capture the intricate nuances of this data, limiting the depth of understanding in spatial distribution and gene interactions. In response, we present Spatial-Temporal Patterns for Downstream Analysis (STPDA), a sophisticated computational framework tailored for spatial transcriptomic data analysis. STPDA leverages high-resolution mapping to bridge the gap between genomics and histopathology, offering a comprehensive perspective on the spatial dynamics of gene expression within tissues. This approach enables a view of cellular function and organization, marking a paradigm shift in our comprehension of biological systems. By employing Autoregressive Moving Average (ARMA) and Long Short-Term Memory (LSTM) models, STPDA effectively deciphers both global and local spatio-temporal dynamics in cellular environments. This integration of spatial-temporal patterns for downstream analysis offers a transformative approach to spatial transcriptomics data analysis. STPDA excels in various single-cell analytical tasks, including the identification of ligand-receptor interactions and cell type classification. Its ability to harness spatial-temporal patterns not only matches but frequently surpasses the performance of existing state-of-the-art methods. To ensure widespread usability and impact, we have encapsulated STPDA in a scalable and accessible Python package, addressing single-cell tasks through advanced spatial-temporal pattern analysis. This development promises to enhance our understanding of cellular biology, offering novel insights and therapeutic strategies, and represents a substantial advancement in the field of spatial transcriptomics.

Social systems for future manufacturing framework: An overarching view of people, organization and society

Drawing on insights from relevant scholarship in the areas of producing engineering, sociology of work and political economy, as well as a series of ‘webinars’ with R&D managers, production managers and trade union representatives conducted between 2021 and 22, we propose an interdisciplinary, multidimensional framework (‘social systems for future manufacturing’) as a means to better understand the shopfloor and societal implications of technological change in the context of the ‘fourth industrial revolution’. Our framework entails three distinct though interrelated levels of analysis (worker, manufacturing, as well as societal), all of which are necessary to engage with in order to understand the implications of digital transformation. We argue that the extent to which employee voice is institutionally embedded at societal level, will have an impact on the way in which new technology will be developed and implemented (namely in a labour-saving or labouraugmenting way). We also discuss relevant factors in terms of workforce skills development at individual and firm level, as well as in terms of national vocational training and development infrastructure, and how these are likely to determine industrial competitiveness in the context of the fourth industrial revolution. Theoretical and managerial implications around work organisation and workforce training are discussed.

A relational view of how social capital contributes to effective digital transformation outcomes

The specifics of why and how network relationships influence digital transformations have not yet been fully understood. We address this gap by drawing on the relational view of organisations to conceptualise network relationships as the source of requisite external non-generic complementarities for the development of dynamic capabilities (absorptive capacity, integration effort and big data analytics) essential for effective digital transformation outcomes. We follow a positivist research design to test the proposed hypotheses by collecting survey responses from informants from 183 Australian healthcare organisations. The statistical findings indicate that social capital affects the digital transformation outcomes through full individual mediations of absorptive capacity (0.13*), integration effort (0.13*) and big data analytics capability (0.05*) and a full serial mediation (0.01*). This empirical evidence provides two significant advancements to both theory and practice: a) by linking development of dynamic capabilities required for digital transformations to external non-generic complementarities embedded in network relationships; and b) by delineating specific pathways through which the dynamic capabilities of absorptive capacity, integration effort and big data analytics influence digital transformation outcomes.

Bordered welfare in Australia: Income management as a bordering technology of neoliberal and colonial governance

In this article we investigate the imposition of compulsory income management on racialised categories of welfare recipient in Australia, identify the contribution made by neoliberalism and settler colonialism in shaping that policy, and characterise income management as a form of ‘bordered welfare’. We begin by acknowledging that key features of neoliberal governance include an ideological aversion to the provision of welfare and the shifting of responsibility onto individuals to promote their own financial security and wellbeing. This has been accompanied by punitive approaches to welfare provision for those perceived to be deficient neoliberal citizens and a commitment to using financial levers, including the welfare system, to shape all manner of human behaviour. We trace the contours of the income management system and report the views of Aboriginal organisations and community leaders about their differential treatment as welfare recipients, noting that restrictions on financial autonomy are a well-documented form of surveillance and control historically directed towards Aboriginal Peoples in Australia. We conclude that this system operates as a form of bordered welfare that classifies certain categories of Aboriginal people as deficient citizens, subjecting them to differential, and detrimental, treatment driven by the ideologies and technologies of both neoliberalism and settler colonialism.