Bread is crucial for food security in Ethiopia, tackling protein malnutrition and vitamin A deficiency. To reduce reliance on imported wheat, supplementing wheat flour with local raw materials is essential. Therefore, this study aims to investigates blending ratio of chickpea and OFSP flour with wheat at different baking temperatures to prepare nutritionally enhanced and high-quality bread. The experiment was conducted in a full factorial design with two factors: flour blending ratio (80:10:10, 70:15:15, 60:20:20, 50:20:30 for wheat, chickpea, and OFSP respectively, and a control of 100% wheat flour) and baking temperatures (180°C, 200°C, and 220°C). The study analyzed the proximate composition of flour and bread, including moisture, ash, protein, fat, fiber, carbohydrates, and β-carotene, while also evaluating the bread's physical and organoleptic properties. Data analysis was conducted using SAS software package version 9.4. The proximate composition of bread showed that substituting wheat with chickpea and orange-fleshed sweet potato increased moisture (28.84 to 35.79%), protein (10.85 to 14.59%), fat (0.85 to 2.05%), fiber (1.49 to 1.84%), ash (0.93 to 2.06%), and β-carotene (0 to 8.04 µg/g of bread). However, it decreased carbohydrate (57.66 to 51.81%) and energy content (281.64 to 257.10 Kcal/100g), due to wheat flour high source of carbohydrate and energy. On the contrary, bread loaf weight increased (123.28 to 131.29 g) due to the superior water absorption capacity of chickpea and OFSP flours compared to wheat. However, loaf volume (359.17 to 205.83 cm³) and specific volume (2.91 to 1.58 cm³/g) decreased due to reduced gluten content in wheat flour. As the proportion of chickpea and OFSP flour increased, sensory acceptability ratings on a 7-point scale decreased: color (6.19 to 2.77), texture (5.78 to 2.62), flavor (5.70 to 2.44), and overall acceptability (5.90 to 2.58) of the bread. In conclusion, blending wheat with chickpea and OFSP flour in bread formulations enhances nutritional quality, especially protein and beta-carotene. Utilizing locally underutilized raw materials is a viable alternative for the growing population.