Structural damage identification (SDI) methods using incomplete modal information can avoid the extension for unmeasured degrees of freedom, but the absence of essential damage information often leads to the failure of SDI. To address this problem, a novel SDI method based on dual sensitivity analysis and optimal sensors placement technique is proposed in this study. Firstly, in the optimal sensor placement technique, an improved eigenvector sensitivity method combined with weighted modal kinetic energy is proposed, which enables the acquisition of eigenvector information related to damage sensitivity, and incorporates it into the modal strain energy sensitivity matrix to obtain the dual sensitivity analysis matrix. Then, the sparsity of structural damage is considered, and the L1 sparse regularization is selected and introduced into the dual sensitivity analysis damage equation for better SDI results. Finally, to assess the effectiveness of the proposed method, a series of numerical simulations and experimental verifications were carried out under different structural damage scenarios. The results indicate that the proposed method can efficiently localize and quantify the structural damage with minimal modal information in one single step.