The power battery in an electric vehicle is an essential part, and the damage to the battery will have a substantial impact on its thermal characteristics. In order to improve the reliability of the air-cooled lithium-ion battery packs in the high temperature environments, this paper offers a more useful and general optimization strategy for the design of the thermal management system for the batteries which have a damaged battery. To ensure the optimal heat dissipation and prolong the battery string operation, the damaged batteries should be swapped out with the backup batteries. The relationship between the target and the design variables which was established using the quadratic polynomial response function is examined. The experimental cases are selected using the optimal Latin hypercube design approach. After optimizing through the multi-island genetic approach, the error between the simulation results and the prediction results is only 0.06 %. The maximum temperature and the maximum temperature difference of the ideal structure are reduced by 4.58 % and 28.05 %, respectively. Then, the backup battery is selected as the sole battery that has the highest temperature of the ideal structure, and each broken battery is replaced by the backup battery when the damaged position is determined. Finally, a parametric equation connecting the temperature and the flow rate is created, and the inlet flow rate is tuned to match the optimal heat dissipation state of the battery pack. The results of the battery thermal management system having a damaged battery in various situations have an important significance for adjusting the operating conditions of the cooling system for the batteries.
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