Opinion Article Research Articles

Doxycycline post-exposure prophylaxis for sexually transmitted infections in South Africa.

South Africa has a large burden of bacterial sexually transmitted infections (STIs) with high rates among men who have sex with men (MSM). Randomised controlled trials have recently demonstrated high effectiveness of doxycycline post-exposure prophylaxis (PEP) for prevention of bacterial STIs in MSM, with 70% - 85% reductions in Chlamydia trachomatis infection and syphilis, and approximately 50% reduction in Neisseria gonorrhoeae infection. Doxycycline PEP was not demonstrated to be effective in reducing C. trachomatis and N. gonorrhoeae infection among Kenyan cisgender women. Although no worrisome trends in antimicrobial resistance (AMR) were observed in the trials, important concerns remain about doxycycline PEP and AMR development in STIs, other pathogens, commensals, and the microbiome. Tetracycline resistance in N. gonorrhoeae is already widespread in South Africa, but emergence of AMR in other STIs would be concerning. Larger sample sizes of doxycycline PEP users with longer follow-up time are needed to understand the impact that doxycycline PEP may have on AMR at individual and population level. In this opinion article, we weigh the benefits of doxycycline PEP for prevention of bacterial STIs against the existing AMR concerns and data gaps in the South African context. Based on the current evidence, we conclude that it would be reasonable to offer doxycycline PEP to high-risk MSM on a case-by-case basis, provided that it is offered by experienced sexual health clinicians in settings that have access to diagnostic STI testing and ongoing AMR surveillance.

The representation of Asian-Americans amid COVID-19: A case study of The Washington Post and CNN

This paper focuses on the representation of the Asian-American community during the COVID-19 pandemic in the opinion articles of the US media about the growing expressions of violence against the community. These articles were posted in The Washington Post and CNN by an Asian-American journalist and an American journalist, respectively. Quantitatively, this study focuses on the proper nouns “Asian(s)” and “American(s)”. Qualitatively, it focuses on identifying patterns and interpreting the meanings underlying the discourse structures employed by each author. For these purposes, corpus linguistics and critical discourse analysis (CDA) were employed. Results show that the Asian-American author uses the proper nouns and rhetorical figures more than their American counterpart, who mostly uses quoting. This, since the former speaks from the community and the latter speaks to the community. It is suggested that the opinion articles discourse should be approached critically since they may influence the readers’ representations around the topic.

Uso de los FAB LAB en el desarrollo de capacidades de innovación en los docentes de Educación para el Trabajo

ABSTRACT This opinion article entitled: Use of FAB LAB in the development of innovation skills in teachers of Education for Work, aims to make known the importance of the use of FAB LAB in the development of innovation skills in teachers of Education for Work. To this end, a review of the emergence of FAB LAB and some examples of how they operate are presented. If such technologies are used by citizens, they would have the capacity to co-design their material culture, Malinowski (2021). It is concluded that it is necessary to boost innovation through technology.

Exploring the Use of Lung Ultrasonography to Assess Cardiac Surgery Patients: A Scoping Review

Objective: Lung ultrasonography (LUS) is a safe, quick, and portable diagnostic tool, which can accurately detect postoperative pulmonary complications, postsurgically, without ionizing radiation. The aim of this scoping review was to map the evidence base regarding the use of LUS to assess cardiac surgery patients. Materials and Methods: The JBI methodology was used to conduct this particular scoping review. Results: In total, 90 publications were identified and of those, 73 were research studies, six were narrative reviews, and 11 were narrative, opinion, and text articles. The studies that were included were predominantly observational cohorts and aimed to determine or compare LUS diagnostic ability, prognostic ability, or both. The LUS methods used with patients were heterogeneous and variably reported. Conclusion: Despite an increasing number of studies since 2014, standardized protocols for the use of LUS are yet to be widely adopted and remain an important area for further work. Future research should consider exploring perceptions and experiences of LUS, the use of LUS in treatment outcome measurement, and use by nonphysician health care professionals.

The need for clear criteria for the selection of participants in scientific workshops.

Scientific workshops are held to develop important documents for clinical practice and policymaking. In these workshops, people with different skills and backgrounds meet to discuss, plan and conduct the development of systematic reviews and clinical guidelines that will be references for researchers, clinicians, patients and other stakeholders, such as insurance companies. The aim of this opinion article is to initiate a discussion on the need for clear and measurable criteria for the selection of participants in scientific workshops. Some examples of workshops in different dental disciplines are used to illustrate that apparently there is no transparent reporting of the criteria used to select participants. Some ethical implications are described in this article, as well as some suggestions to increase transparency in the process of selecting the participants for these scientific workshops. It is expected that overall trust in research, including from parties not directly associated with it, will increase when these selection criteria are transparently reported.

Cell Therapy of Severe Ischemia in People with Diabetic Foot Ulcers-Do We Have Enough Evidence?

This current opinion article critically evaluates the efficacy of autologous cell therapy (ACT) for chronic limb-threatening ischemia (CLTI), especially in people with diabetes who are not candidates for standard revascularization. This treatment approach has been used in 'no-option' CLTI in the last two decades and more than 1700 patients have received ACT worldwide. Here we analyze the level of published evidence of ACT as well as our experience with this treatment method. Many studies have shown that ACT is safe and an effective method for patients with the most severe lower limb ischemia. However, some trials did not show any benefit of ACT, and there is some heterogeneity in the types of injected cells, route of administration and assessed endpoints. Nevertheless, we believe that ACT plays an important role in a comprehensive treatment of patients with diabetic foot and severe ischemia.

A scoping review of emotions and related constructs in simulation-based education research articles

BackgroundWhile acknowledgement of emotions’ importance in simulation-based education is emerging, there are concerns regarding how education researchers understand the concept of emotions for them to deliberately incorporate emotionally charged scenarios into simulation-based education. This concern is highlighted especially in the context of medical education often lacking strong theoretical integration. To map out how current simulation-based education literature conceptualises emotion, we conducted a scoping review on how emotions and closely related constructs (e.g. stress, and emotional intelligence) are conceptualised in simulation-based education articles that feature medical students, residents, and fellows.MethodsThe scoping review was based on articles published in the last decade identified through database searches (EMBASE and Medline) and hand-searched articles. Data extraction included the constructs featured in the articles, their definitions, instruments used, and the types of emotions captured. Only empirical articles were included (e.g. no review or opinion articles). Data were charted via descriptive analyses.ResultsA total of 141 articles were reviewed. Stress was featured in 88 of the articles, while emotions and emotional intelligence were highlighted in 45 and 34 articles respectively. Conceptualisations of emotions lacked integration of theory. Measurements of emotions mostly relied on self-reports while stress was often measured via physiological and self-report measurements. Negative emotions such as anxiety were sometimes seen as interchangeable with the term stress. No inferences were made about specific emotions of participants from their emotional intelligence.ConclusionsOur scoping review illustrates that learners in simulation-based education are most often anxious and fearful. However, this is partially due to medical education prioritising measuring negative emotions. Further theoretical integration when examining emotions and stress may help broaden the scope towards other kinds of emotions and better conceptualisations of their impact. We call for simulation education researchers to reflect on how they understand emotions, and whether their understanding may neglect any specific aspect of affective experiences their simulation participants may have.

Avoiding Uncertainty and Conflict: The Importance of Clear Expectations and Rules for Remote Workers

There is little doubt that COVID-19 has changed the workplace in numerous aspects. We witness dramatic transformations in turnover rates, extinction of professions, the basic motivation needs of employees etc. One of the most prominent changes we have seen is the rise of the remote workers and its consequences. Employees have worked from home prior the COVID-19 pandemic, but this phenomenon had grown exponentially during the pandemic. This rapid unprecedent rate required some industries to change completely the way the operate in terms of measurement, training, evaluating, managing, communicating etc. In this opinion article I will address this issue by identifying the complex consequences of remote working, mostly by discussing the importance of setting clear expectations and boundaries. I will also offer organizations some practices that could mitigate the negative outcomes of remote working.

Hematopoietic Stem Cells Transplant (HSCT)-Related Chronic Pulmonary Diseases: An Overview.

Recipients of HSCT have a high risk of infective and non-infective pulmonary diseases. Most patients with pulmonary involvement present multiple pathogenetic mechanisms simultaneously with complex interactions. Therefore, it can be difficult to distinguish the contributions of each one and to perform studies on this subject. In this opinion article, we discuss only chronic pulmonary manifestations, focusing on LONIPCs (late-onset non-infectious pulmonary complications). This term embraces drug-related toxicity, allergies, and chronic pulmonary graft versus host disease (GvHD) in all its recently identified clinical variants. Among LONIPCs, GvHD represents the most critical in terms of morbidity and mortality, despite the rapid development of new treatment options. A recently emerging perspective suggests that pulmonary lung rejection in transplant patients shares striking similarities with the pathogenesis of GvHD. In a pulmonary transplant, the donor organ is damaged by the host immune system, whereas in GvHD, the donor immune system damages the host organs. It constitutes the most significant breakthrough in recent years and is highly promising for both hematologists and thoracic transplant surgeons. The number of patients with LONIPCs is scarce, with heterogenous clinical characteristics often involving several pathogenetic mechanisms, making it challenging to conduct randomized controlled trials. Therefore, the body of evidence in this field is scarce and generally of low quality, leading to jeopardized choices in terms of immunosuppressive treatment. Moreover, it risks being outdated by common practice due to the quick evolution of knowledge about the diagnosis and treatment of LONIPCs. The literature is even more pitiful for children with pulmonary involvement related to HSCT.

Sustainable Service-Learning through Massive Open Online Courses

In this opinion article, I discuss the role of online learning, especially Massive Open Online Courses (MOOCs), in making what I call “resource-intensive pedagogies” more sustainable. Specifically, I zero in on the framework of service-learning. I present a case study of a long-standing and successful service-learning project in the context of teacher education. This case-based evidence suggests that MOOCs can be highly instrumental in individualizing course content and increasing the course concept’s scalability. The article ends by suggesting three avenues for further research to explore this nexus of online learning and resource-intensive pedagogies.

Edaphosphere: A Perspective of Soil Inside the Biosphere

The integration of soil into ecology in the current climate crisis is essential for correct environmental management. Soil is a part of ecosystems; above all, it is a component of the biosphere. It is necessary to establish a definition of soil that integrates biota and biodiversity without losing sight of the historical development of edaphology, the science that studies soil. In this opinion article, we proposes a definition for all soils grouped together in the edaphosphere, which is, in fact, a subsystem of the biosphere. In addition, we highlight the importance of the definition of soil provided by Vasily Dokuchaev, the founder of edaphology, with respect to the integration of soil into the biosphere and the differences between the concepts of pedosphere and edaphosphere.

Opinion: Atmospheric multiphase chemistry – past, present, and future

Abstract. Multiphase chemistry occurs between chemicals in different atmospheric phases, typically involving gas–solid and gas–liquid interactions. The importance of atmospheric multiphase chemistry has long been recognized. Its central role extends from acid precipitation and stratospheric ozone depletion to its impact on the oxidizing capacity of the troposphere and to the roles that aerosol particles play in driving chemistry–climate interactions and affecting human health. This opinion article briefly introduces the subject of multiphase chemistry and tracks its development before and after the start of Atmospheric Chemistry and Physics. Most of the article focuses on research opportunities and challenges in the field. Central themes are that a fundamental understanding of the chemistry at the molecular level underpins the ability of atmospheric chemistry to accurately predict environmental change and that the discipline of multiphase chemistry is strongest when tightly connected to atmospheric modeling and field observations.

Do respiratory physicians not care about people who smoke?

Nicotine containing vapes (e-cigarettes) are an effective tool to support people who smoke to quit tobacco. Despite this clinicians are wary of promoting vaping to their patients due to concerns that there may not be 'enough' evidence and about youth uptake of vaping. In this opinion article we discuss clinicians' views of vaping and consider the implications that harm misperceptions may have for public health.

Phenomics: conceptualization and importance for plant physiology.

Phenomics is a relatively new discipline of biology that has been widely applied in several fields, mainly in crop sciences. We reviewed the concepts used in this discipline (particularly for plants) and found a lack of consensus on what defines a phenomic study. Furthermore, phenomics has been primarily developed around its technical aspects (operationalization), while the conceptual framework of the actual research lags behind. Each research group has given its own interpretation of this 'omic' and thus unwittingly created a 'conceptual controversy'. Addressing this issue is of particular importance, as the experimental designs and concepts of phenomics are so diverse that it is difficult to compare studies. In this opinion article, we evaluate the conceptual framework of phenomics.

Synthesis of Attitudes and Opinions of Enthusiasts on Self-Directed Language Learning with Online Language Resources

This study synthesized the attitudes and opinions of language enthusiasts engaged in self-directed language learning through online resources. Enthusiasts include those who have learned languages online or have a keen interest in the mode, whether formally or informally. The motivation for this study stems from the increasing trend of language learners turning to online platforms, driven by technological convenience and recent events like the COVID-19 pandemic. Notably, research primarily focuses on these resources in formal settings, leaving a gap in understanding their role in informal learning. The researchers employed a qualitative phenomenological approach, analyzing twenty opinionated articles from diverse online sources. A purposive sampling technique ensured a balanced representation of positive, negative, and neutral opinions. Data analysis involved extracting and thematising perspectives from authors, commentators, respondents and customer reviews, covering language learning applications like Duolingo, Rosetta Stone and Babbel. Enthusiasts predominantly view online platforms as effective when combined with traditional methods, emphasizing learner motivation as crucial to technology-enhanced language learning. The study calls for innovative approaches from resource designers and administrators to sustain user engagement. In summary, this study enhances the understanding of enthusiasts' attitudes and opinions regarding self-directed language learning through online resources, highlighting the interplay between technology, motivation and effective language acquisition.

Keep It Simple: Using README Files to Advance Standardization in Chronobiology.

Standardization plays a crucial role in ensuring the reliability, reproducibility, and interoperability of research data in the biomedical sciences. Metadata standards are one foundation for the FAIR (Findable, Accessible, Interoperable, and Reusable) principles of data management. They facilitate data discovery, understanding, and reuse. However, the adoption of metadata standards in biological research lags in practice. Barriers such as complexity, lack of incentives, technical challenges, resource constraints, and resistance to change hinder widespread adoption. In the field of chronobiology, standardization is essential but faces particular challenges due to the longitudinal nature of experimental data, diverse model organisms, and varied measurement techniques. To address these challenges, we propose an approach that emphasizes simplicity and practicality: the development of README templates tailored for particular data types and species. Through this opinion article, our intention is to initiate a dialogue and commence a community-driven standardization process by engaging potential contributors and collaborators.

Incorporating phylogenetic conservatism and trait collinearity into machine learning frameworks can better predict macroinvertebrate traits

In the face of rapid environmental changes, understanding and monitoring biological traits and functional diversity are crucial for effective biomonitoring. However, when it comes to freshwater macroinvertebrates, a significant dearth of biological trait data poses a major challenge. In this opinion article, we put forward a machine-learning framework that incorporates phylogenetic conservatism and trait collinearity, aiming to provide a better vision for predicting macroinvertebrate traits in freshwater ecosystems. By adopting this proposed framework, we can advance biomonitoring efforts in freshwater ecosystems. Accurate predictions of macroinvertebrate traits enable us to assess functional diversity, identify environmental stressors, and monitor ecosystem health more effectively. This information is vital for making informed decisions regarding conservation and management strategies, especially in the context of rapidly changing environments.

Exploring electronic cigarette portrayals: a content and thematic analysis of African online news coverage

BackgroundElectronic cigarette use has surged internationally in recent years, with numerous countries noting an uptick in users. Despite this, the portrayal of e-cigarette usage in African news remains unclear.MethodsThis research investigates the subject, employing a mixed-methodology approach. The study units were news articles on electronic cigarette use retrieved from AllAfrica, an online African news archive. A total of 38 online news and opinion articles published between June 2017 and June 2022 qualified the exclusion and inclusion criteria. A content analysis revealed prevalent codes and themes, while a thematic analysis explored the association between news sources and framing.ResultsThe results indicate that articles and arguments presenting e-cigarettes positively outnumber those with a negative slant. The health impacts of electronic cigarettes emerged as the most discussed topic, with health authorities frequently cited as news sources. However, these health authorities often lacked a unified stance on e-cigarette safety.ConclusionThe lack of consensus among health officials could have public health consequences, possibly resulting in the formulation of uninformed policies.

Empowered through our diversity: How to bring in a new age of plant science collaboration

Societal Impact StatementClimate‐change and land‐use intensification are degrading ecosystems globally, impeding their services to humans (e.g., food security and human health). The United Nations 13th and 15th Sustainable Development Goals (SDGs) call for action to protect and restore ecosystems. Only transdisciplinary research can unravel the multitudes of interacting ecosystem parts that could help accomplish these SDGs. However, a major challenge will be overcoming material, social and other types of barriers that prevent collaborations. This study explores some of these challenges and seeks the views of the community through a survey to help develop a new age of plant science collaboration.SummaryIn this opinion article, we explore the problem of missed opportunities for collaboration in fields related to plant science. Lack of awareness of the scientific output, which can be gained from transdisciplinary collaborations, as well as the opportunities they can provide for early‐career scientists, may contribute to this. Here, we name communication barriers as particularly inhibitory to the formation of collaborations and propose possible solutions to overcome these barriers. Eventual action towards these solutions needs to be based on the opinions of the community. We thus intend this article to initiate a dialogue among researchers across the many disciplines of plant science about the feasibility of these proposed solutions. The questionnaire included with this article, intended for the broad plant research community, we believe could help us gain the necessary information to proceed in addressing communication barriers to transdisciplinary science collaborations. We provide a theoretical framework, examples and timely topics as discussion points to inspire participants of the questionnaire to contribute their voice to shaping a new age of plant science collaboration.

The Relationship between Whole-Milk Dairy Foods and Metabolic Health Highlights an Opportunity for Dietary Fat Recommendations to Evolve with the State of the Science.

The science of dietary fats has evolved, and a body of evidence indicates they are complex bioactive nutrients that have different effects on health depending on their food source, chain length, degree of saturation, and other factors that can be affected by food processing, handling, and storage. As such, it is becoming increasingly clear that the effects of foods on obesity and metabolic health cannot be predicted simply with their fat content. The aim of this opinion article is to provide a brief overview of select recent research on the effects of whole-milk dairy foods on body composition and indicators of metabolic health across the lifespan to show the gap between current knowledge and dietary guidance. As the state of the science on dietary fats and human health evolves to consider the complexity of food matrices, the total nutrient package they deliver, and the health impacts associated with dietary patterns, so too must guidelines for dietary fat.