IntroductionIn portal hypertension patient, there will be splanchnic vasodilatation resulting in decreased effective arterial volume hence activation of antinaturetic factors causing sodium retention with impaired free water excretion. A patent shunt should reverse this sodium imbalance to normal. Hence, serial spot urine sodium is used as surrogate marker for shunt patency.BackgroundAn open shunt can frequently be estimated clinically by measuring serial urinary sodium concentrations. If the concentration is higher than 10 mg/dL, the shunt is almost certainly open. Our prospective study is designed to verify how best serial spot sodium predicts the patency of the shunt and its clinical relevance.Materials and Methods9 portal hypertensive patients with CHILDS A underwent splenorenal shunt for upper GI bleed. These patients serially followed with spot urine sodium on PRE OP base line, POD 1, POD 5, and at the time of discharge with simultaneous Doppler study of the shunt.Results2 patients had complete shunt obstruction with serial spot sodium of less than 10mg/dl. 3 patients had trickle flow of blood with partial thrombotic obstruction with serial spot sodium greater than 10mg/dl. 4 patients with patent shunt also showed greater than 10 mg/dl.ConclusionSerial Urine spot sodium as marker of shunt patency is correlating well for complete obstruction of the shunt. But, it could not differentiate partial shunt occlusion from patent shunt. Interestingly, it predicted the re-bleed earlier than clinical presentation in those complete shunt obstruction patients. IntroductionIn portal hypertension patient, there will be splanchnic vasodilatation resulting in decreased effective arterial volume hence activation of antinaturetic factors causing sodium retention with impaired free water excretion. A patent shunt should reverse this sodium imbalance to normal. Hence, serial spot urine sodium is used as surrogate marker for shunt patency. In portal hypertension patient, there will be splanchnic vasodilatation resulting in decreased effective arterial volume hence activation of antinaturetic factors causing sodium retention with impaired free water excretion. A patent shunt should reverse this sodium imbalance to normal. Hence, serial spot urine sodium is used as surrogate marker for shunt patency. BackgroundAn open shunt can frequently be estimated clinically by measuring serial urinary sodium concentrations. If the concentration is higher than 10 mg/dL, the shunt is almost certainly open. Our prospective study is designed to verify how best serial spot sodium predicts the patency of the shunt and its clinical relevance. An open shunt can frequently be estimated clinically by measuring serial urinary sodium concentrations. If the concentration is higher than 10 mg/dL, the shunt is almost certainly open. Our prospective study is designed to verify how best serial spot sodium predicts the patency of the shunt and its clinical relevance. Materials and Methods9 portal hypertensive patients with CHILDS A underwent splenorenal shunt for upper GI bleed. These patients serially followed with spot urine sodium on PRE OP base line, POD 1, POD 5, and at the time of discharge with simultaneous Doppler study of the shunt. 9 portal hypertensive patients with CHILDS A underwent splenorenal shunt for upper GI bleed. These patients serially followed with spot urine sodium on PRE OP base line, POD 1, POD 5, and at the time of discharge with simultaneous Doppler study of the shunt. Results2 patients had complete shunt obstruction with serial spot sodium of less than 10mg/dl. 3 patients had trickle flow of blood with partial thrombotic obstruction with serial spot sodium greater than 10mg/dl. 4 patients with patent shunt also showed greater than 10 mg/dl. 2 patients had complete shunt obstruction with serial spot sodium of less than 10mg/dl. 3 patients had trickle flow of blood with partial thrombotic obstruction with serial spot sodium greater than 10mg/dl. 4 patients with patent shunt also showed greater than 10 mg/dl. ConclusionSerial Urine spot sodium as marker of shunt patency is correlating well for complete obstruction of the shunt. But, it could not differentiate partial shunt occlusion from patent shunt. Interestingly, it predicted the re-bleed earlier than clinical presentation in those complete shunt obstruction patients. Serial Urine spot sodium as marker of shunt patency is correlating well for complete obstruction of the shunt. But, it could not differentiate partial shunt occlusion from patent shunt. Interestingly, it predicted the re-bleed earlier than clinical presentation in those complete shunt obstruction patients.
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